JP2021534794A5 - - Google Patents
Info
- Publication number
- JP2021534794A5 JP2021534794A5 JP2021510957A JP2021510957A JP2021534794A5 JP 2021534794 A5 JP2021534794 A5 JP 2021534794A5 JP 2021510957 A JP2021510957 A JP 2021510957A JP 2021510957 A JP2021510957 A JP 2021510957A JP 2021534794 A5 JP2021534794 A5 JP 2021534794A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- composition according
- viral vector
- gars
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024107253A JP2024133570A (ja) | 2018-08-29 | 2024-07-03 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
| JP2026072273A JP2026120817A (ja) | 2018-08-29 | 2026-04-24 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862724604P | 2018-08-29 | 2018-08-29 | |
| US62/724,604 | 2018-08-29 | ||
| PCT/US2019/048832 WO2020047268A1 (en) | 2018-08-29 | 2019-08-29 | Products and methods for inhibition of expression of mutant gars protein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107253A Division JP2024133570A (ja) | 2018-08-29 | 2024-07-03 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021534794A JP2021534794A (ja) | 2021-12-16 |
| JP2021534794A5 true JP2021534794A5 (enExample) | 2022-08-31 |
Family
ID=67953864
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021510957A Pending JP2021534794A (ja) | 2018-08-29 | 2019-08-29 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
| JP2024107253A Withdrawn JP2024133570A (ja) | 2018-08-29 | 2024-07-03 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
| JP2026072273A Pending JP2026120817A (ja) | 2018-08-29 | 2026-04-24 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107253A Withdrawn JP2024133570A (ja) | 2018-08-29 | 2024-07-03 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
| JP2026072273A Pending JP2026120817A (ja) | 2018-08-29 | 2026-04-24 | 変異型ｇａｒｓタンパク質の発現を阻害するための生成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20210324417A1 (enExample) |
| EP (1) | EP3844284A1 (enExample) |
| JP (3) | JP2021534794A (enExample) |
| AU (1) | AU2019328270B2 (enExample) |
| CA (1) | CA3110665A1 (enExample) |
| WO (1) | WO2020047268A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022015715A1 (en) * | 2020-07-13 | 2022-01-20 | The Trustees Of The University Of Pennsylvania | Compositions useful for treatment of charcot-marie-tooth disease |
| WO2022119826A1 (en) * | 2020-12-01 | 2022-06-09 | Research Institute At Nationwide Children's Hospital | Products and methods for inhibition of expression of peripheral myelin protein-22 |
| US20240401046A1 (en) * | 2021-10-07 | 2024-12-05 | Research Institute At Nationwide Children' S Hospital | Products and methods for myelin protein zero silencing and treating cmt1b disease |
| IT202200009395A1 (it) * | 2022-05-09 | 2022-08-09 | Giam Pharma Int Sarl | Attività antitumorale del meso-(p-acetamidophenyl)-calix[4]pirrolo mediante l’Inibizione dell’attività enzimatica della proteina Glicil-tRNA Sintasi 1 (GARS1) |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| EP0733103B1 (en) | 1993-11-09 | 2004-03-03 | Targeted Genetics Corporation | Generation of high titers of recombinant aav vectors |
| DE69433922T2 (de) | 1993-11-09 | 2005-07-28 | Medical College Of Ohio, Toledo | Stabile zellinie, die in der lage ist, das replikationsgen des adenoassoziertenvirus zu exprimieren |
| US5658785A (en) | 1994-06-06 | 1997-08-19 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
| US5856152A (en) | 1994-10-28 | 1999-01-05 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV vector and methods of use therefor |
| WO1996017947A1 (en) | 1994-12-06 | 1996-06-13 | Targeted Genetics Corporation | Packaging cell lines for generation of high titers of recombinant aav vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| JPH11511326A (ja) | 1995-08-30 | 1999-10-05 | ジエンザイム コーポレイション | アデノウィルスおよびａａｖの精製 |
| JPH11514853A (ja) | 1995-09-08 | 1999-12-21 | ジエンザイム コーポレイション | 遺伝子治療のための改良されたａａｖベクター |
| US5910434A (en) | 1995-12-15 | 1999-06-08 | Systemix, Inc. | Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant |
| EP1696036B1 (en) | 1996-09-06 | 2010-04-21 | The Trustees of The University of Pennsylvania | Use of recombinant adeno-associated virus in the manufacture of a medicament for gene therapy via muscle cells |
| CA2995542A1 (en) | 1997-09-05 | 1999-03-11 | Genzyme Corporation | Methods for generating high titer helper-free preparations of recombinant aav vectors |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6258595B1 (en) | 1999-03-18 | 2001-07-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for helper-free production of recombinant adeno-associated viruses |
| JP2004514407A (ja) | 2000-04-28 | 2004-05-20 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 異種キャプシド中にシュードタイピングされたａａｖ５キャプシドおよびａａｖ５ベクターを含む組換えａａｖベクター |
| WO2002053703A2 (en) | 2001-01-05 | 2002-07-11 | Children's Hospital, Inc. | Aav2 vectors and methods |
| DK2359869T3 (en) | 2001-12-17 | 2019-04-15 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof |
| WO2008134646A2 (en) * | 2007-04-26 | 2008-11-06 | University Of Iowa Research Foundation | Rna interference suppression of neurodegenerative diseases and methods of use thereof |
| DK2164967T3 (en) * | 2007-05-31 | 2015-10-19 | Univ Iowa Res Found | Reduction of off-target rna interferenstoksicitet |
| JP6116479B2 (ja) * | 2010-07-12 | 2017-04-19 | エータイアー ファーマ， インコーポレイテッド | グリシルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| DE102012007232B4 (de) | 2012-04-07 | 2014-03-13 | Susanne Weller | Verfahren zur Herstellung von rotierenden elektrischen Maschinen |
| JP2015092462A (ja) | 2013-09-30 | 2015-05-14 | Tdk株式会社 | 正極及びそれを用いたリチウムイオン二次電池 |
| WO2015141521A1 (ja) | 2014-03-21 | 2015-09-24 | 株式会社日立国際電気 | 基板処理装置、半導体装置の製造方法及び記録媒体 |
| JP6197169B2 (ja) | 2014-09-29 | 2017-09-20 | 東芝メモリ株式会社 | 半導体装置の製造方法 |
| WO2017153936A1 (en) * | 2016-03-10 | 2017-09-14 | Novartis Ag | Chemically modified messenger rna's |
-
2019
- 2019-08-29 AU AU2019328270A patent/AU2019328270B2/en active Active
- 2019-08-29 CA CA3110665A patent/CA3110665A1/en active Pending
- 2019-08-29 WO PCT/US2019/048832 patent/WO2020047268A1/en not_active Ceased
- 2019-08-29 EP EP19768951.6A patent/EP3844284A1/en active Pending
- 2019-08-29 JP JP2021510957A patent/JP2021534794A/ja active Pending
- 2019-08-29 US US17/271,377 patent/US20210324417A1/en active Pending
-
2024
- 2024-07-03 JP JP2024107253A patent/JP2024133570A/ja not_active Withdrawn
-
2026
- 2026-04-24 JP JP2026072273A patent/JP2026120817A/ja active Pending