|
CA136551A
(en)
|
1911-08-03 |
1911-10-31 |
Hedwig Heeron |
Rolling mill
|
|
US4690915A
(en)
|
1985-08-08 |
1987-09-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adoptive immunotherapy as a treatment modality in humans
|
|
IE20030749A1
(en)
|
1991-05-03 |
2003-11-12 |
Indiana University Foundation |
Human notch and delta binding domains in torporythmic proteins, and methods based thereon
|
|
US5420032A
(en)
|
1991-12-23 |
1995-05-30 |
Universitge Laval |
Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence
|
|
US5792632A
(en)
|
1992-05-05 |
1998-08-11 |
Institut Pasteur |
Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
|
|
US5780300A
(en)
|
1995-09-29 |
1998-07-14 |
Yale University |
Manipulation of non-terminally differentiated cells using the notch pathway
|
|
WO1997034634A1
(en)
|
1996-03-20 |
1997-09-25 |
Sloan-Kettering Institute For Cancer Research |
Single chain fv constructs of anti-ganglioside gd2 antibodies
|
|
CN1524583A
(zh)
*
|
1996-11-07 |
2004-09-01 |
|
能够表达Notch-配体的基因在制备用于免疫治疗的药物中的应用
|
|
EP1109921A4
(en)
|
1998-09-04 |
2002-08-28 |
Sloan Kettering Inst Cancer |
FUSION RECEPTORS SPECIFIC TO MEMBRANE SPECIFIC PROSTATIC ANTIGEN AND USES THEREOF
|
|
US20020131960A1
(en)
|
2000-06-02 |
2002-09-19 |
Michel Sadelain |
Artificial antigen presenting cells and methods of use thereof
|
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
|
US6689744B2
(en)
|
2000-09-22 |
2004-02-10 |
Genentech, Inc. |
Notch receptor agonists and uses
|
|
US20030119771A1
(en)
|
2001-08-22 |
2003-06-26 |
Rompaey Luc Van |
Modulators of bone homeostasis identified in a high-throughput screen
|
|
JP2003093048A
(ja)
*
|
2001-09-26 |
2003-04-02 |
Asahi Kasei Corp |
新規細胞製剤製造用培養媒体
|
|
US20030170238A1
(en)
|
2002-03-07 |
2003-09-11 |
Gruenberg Micheal L. |
Re-activated T-cells for adoptive immunotherapy
|
|
AU2003215869B2
(en)
|
2002-03-15 |
2008-04-24 |
Cellectis |
Hybrid and single chain meganucleases and use thereof
|
|
AU2003226537A1
(en)
*
|
2002-04-05 |
2003-10-27 |
Lorantis Limited |
Modulators of the notch signalling pathway and uses thereof in medical treatment
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
EP1549347A1
(en)
*
|
2002-10-09 |
2005-07-06 |
Lorantis Limited |
Modulation of immune function
|
|
JP2006517533A
(ja)
*
|
2003-01-23 |
2006-07-27 |
ロランティス リミテッド |
Notchシグナル伝達経路のアクチベーターを用いる自己免疫疾患の治療
|
|
EP3202899B1
(en)
|
2003-01-28 |
2020-10-21 |
Cellectis |
Custom-made meganuclease and use thereof
|
|
CA2589279A1
(en)
*
|
2004-11-24 |
2006-06-01 |
Val-Chum, S.E.C. |
Methods to identify, prepare, and use naive t cell recent thymic emigrants
|
|
WO2007027226A2
(en)
*
|
2005-04-28 |
2007-03-08 |
Board Of Regents, The University Of Texas System |
Systems and methods for the production of differentiated cells
|
|
ES2582091T3
(es)
|
2005-10-18 |
2016-09-09 |
Precision Biosciences |
Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas
|
|
PE20080891A1
(es)
|
2006-10-19 |
2008-08-25 |
Genentech Inc |
Anticuerpos anti-notch3 y composiciones que los comprenden
|
|
RU2461569C2
(ru)
|
2006-10-19 |
2012-09-20 |
Дженентек, Инк. |
Агонистические антитела против notch3 и их применение для лечения notch3-ассоциированных заболеваний
|
|
WO2008092445A2
(de)
*
|
2007-01-30 |
2008-08-07 |
Deutsches Rheuma-Forschungszentrum Berlin |
Verfahren zur modulation der immunantwort durch aktivierung oder inaktivierung des notch und/oder stat4 signalweges
|
|
SI2856876T1
(en)
|
2007-03-30 |
2018-04-30 |
Memorial Sloan-Kettering Cancer Center |
Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes
|
|
CA2742969A1
(en)
|
2008-11-07 |
2010-05-14 |
Fabrus Llc |
Anti-dll4 antibodies and uses thereof
|
|
US20110286916A1
(en)
|
2008-11-20 |
2011-11-24 |
Jose Miguel Aste-Amezaga |
Generation and characterization of anti-notch antibodies for therapeutic and diagnostic use
|
|
WO2010141249A2
(en)
|
2009-06-02 |
2010-12-09 |
Merck Sharp & Dohme Corp. |
Generation, characterization and uses thereof of anti-notch3 antibodies
|
|
US8586526B2
(en)
|
2010-05-17 |
2013-11-19 |
Sangamo Biosciences, Inc. |
DNA-binding proteins and uses thereof
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
WO2013126726A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Double transgenic t cells comprising a car and a tcr and their methods of use
|
|
AU2013266968B2
(en)
|
2012-05-25 |
2017-06-29 |
Emmanuelle CHARPENTIER |
Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
|
|
US10316289B2
(en)
*
|
2012-09-06 |
2019-06-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T memory stem cell populations
|
|
US20140186843A1
(en)
|
2012-12-12 |
2014-07-03 |
Massachusetts Institute Of Technology |
Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
|
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
|
US10696946B2
(en)
*
|
2013-02-22 |
2020-06-30 |
The Board Of Trustees Of The University Of Illinois |
T-REG cell expansion
|
|
US9683039B2
(en)
|
2013-03-14 |
2017-06-20 |
New York University |
Notch agonists for the treatment of cancer
|
|
CA2930877A1
(en)
|
2013-11-18 |
2015-05-21 |
Crispr Therapeutics Ag |
Crispr-cas system materials and methods
|
|
CA2948871A1
(en)
|
2014-05-22 |
2015-11-26 |
Fred Hutchinson Cancer Research Center |
Lilrb2 and notch-mediated expansion of hematopoietic precursor cells
|
|
CN106459919B
(zh)
|
2014-06-04 |
2021-03-23 |
弗莱德哈钦森癌症研究中心 |
使用notch 1和/或notch 2激动剂扩增和植入干细胞
|
|
HK1243631A1
(zh)
*
|
2014-10-27 |
2018-07-20 |
Fred Hutchinson Cancer Research Center |
用於提高过继细胞免疫疗法效力的组合物和方法
|
|
US10947502B2
(en)
*
|
2015-10-20 |
2021-03-16 |
FUJIFILM Cellular Dynamics, Inc. |
Methods for directed differentiation of pluripotent stem cells to immune cells
|
|
AU2016341529B2
(en)
*
|
2015-10-22 |
2023-03-30 |
Juno Therapeutics Gmbh |
Methods for culturing cells and kits and apparatus for same
|
|
SG11201803419PA
(en)
*
|
2015-10-30 |
2018-05-30 |
The Regents Of The Universtiy Of California |
Methods of generating t-cells from stem cells and immunotherapeutic methods using the t-cells
|
|
WO2017173551A1
(en)
*
|
2016-04-08 |
2017-10-12 |
The Governing Council Of The University Of Toronto |
Method for generating progenitor t cells from stem and/or progenitor cells and use of same
|
|
US11261250B2
(en)
|
2016-07-22 |
2022-03-01 |
Fred Hutchinson Cancer Research Center |
Bi-specific molecule for cell-specific Notch inhibition and related methods and compositions
|