|
CA136551A
(en)
|
1911-08-03 |
1911-10-31 |
Hedwig Heeron |
Rolling mill
|
|
US4690915A
(en)
|
1985-08-08 |
1987-09-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adoptive immunotherapy as a treatment modality in humans
|
|
IE20030749A1
(en)
|
1991-05-03 |
2003-11-12 |
Indiana University Foundation |
Human notch and delta binding domains in torporythmic proteins, and methods based thereon
|
|
US5420032A
(en)
|
1991-12-23 |
1995-05-30 |
Universitge Laval |
Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence
|
|
US5792632A
(en)
|
1992-05-05 |
1998-08-11 |
Institut Pasteur |
Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
|
|
US5780300A
(en)
|
1995-09-29 |
1998-07-14 |
Yale University |
Manipulation of non-terminally differentiated cells using the notch pathway
|
|
WO1997034634A1
(en)
|
1996-03-20 |
1997-09-25 |
Sloan-Kettering Institute For Cancer Research |
Single chain fv constructs of anti-ganglioside gd2 antibodies
|
|
CZ295997B6
(cs)
*
|
1996-11-07 |
2005-12-14 |
Lorantis Limited |
Farmaceutický prostředek s obsahem ligandu Notch a způsob tvorby T-buněk
|
|
JP2002524081A
(ja)
|
1998-09-04 |
2002-08-06 |
スローン − ケッタリング インスティチュート フォー キャンサー リサーチ |
前立腺−特異的膜抗原に特異的な融合受容体およびその使用
|
|
US20020131960A1
(en)
|
2000-06-02 |
2002-09-19 |
Michel Sadelain |
Artificial antigen presenting cells and methods of use thereof
|
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
|
US6689744B2
(en)
|
2000-09-22 |
2004-02-10 |
Genentech, Inc. |
Notch receptor agonists and uses
|
|
US20030119771A1
(en)
|
2001-08-22 |
2003-06-26 |
Rompaey Luc Van |
Modulators of bone homeostasis identified in a high-throughput screen
|
|
JP2003093048A
(ja)
*
|
2001-09-26 |
2003-04-02 |
Asahi Kasei Corp |
新規細胞製剤製造用培養媒体
|
|
US20030170238A1
(en)
|
2002-03-07 |
2003-09-11 |
Gruenberg Micheal L. |
Re-activated T-cells for adoptive immunotherapy
|
|
US20060078552A1
(en)
|
2002-03-15 |
2006-04-13 |
Sylvain Arnould |
Hybrid and single chain meganucleases and use thereof
|
|
JP2006506322A
(ja)
*
|
2002-04-05 |
2006-02-23 |
ロランティス リミテッド |
内科療法
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
WO2004032969A1
(en)
*
|
2002-10-09 |
2004-04-22 |
Lorantis Limited |
Modulation of immune function
|
|
JP2006517533A
(ja)
*
|
2003-01-23 |
2006-07-27 |
ロランティス リミテッド |
Notchシグナル伝達経路のアクチベーターを用いる自己免疫疾患の治療
|
|
US20060153826A1
(en)
|
2003-01-28 |
2006-07-13 |
Sylvain Arnould |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
|
|
US20080112934A1
(en)
*
|
2004-11-24 |
2008-05-15 |
Rafick-Pierre Sekaly |
Methods To Identify, Prepare, And Use Naive T Cell Recent Thymic Emigrants
|
|
WO2007027226A2
(en)
*
|
2005-04-28 |
2007-03-08 |
Board Of Regents, The University Of Texas System |
Systems and methods for the production of differentiated cells
|
|
CA2891996A1
(en)
|
2005-10-18 |
2007-04-26 |
Duke University |
Rationally-designed meganucleases with altered sequence specificity and dna-binding affinity
|
|
EP2081962B1
(en)
|
2006-10-19 |
2018-10-03 |
Genentech, Inc. |
Novel anti-notch3 antibodies and their use in the detection and diagnosis of disease
|
|
AR063494A1
(es)
|
2006-10-19 |
2009-01-28 |
Genentech Inc |
Anticuerpos agonistas anti notch3 y su uso en el tratamiento de las enfermedades relacionadas con el gen notch3
|
|
WO2008092445A2
(de)
*
|
2007-01-30 |
2008-08-07 |
Deutsches Rheuma-Forschungszentrum Berlin |
Verfahren zur modulation der immunantwort durch aktivierung oder inaktivierung des notch und/oder stat4 signalweges
|
|
CA2682527C
(en)
|
2007-03-30 |
2017-07-11 |
Memorial Sloan-Kettering Cancer Center |
Constitutive expression of costimulatory ligands on adoptively transferred t lymphocytes
|
|
DK2356270T3
(da)
|
2008-11-07 |
2016-12-12 |
Fabrus Llc |
Kombinatoriske antistofbiblioteker og anvendelser deraf
|
|
WO2010059543A1
(en)
|
2008-11-20 |
2010-05-27 |
Merck Sharp & Dohme Corp. |
Generation and characterization of anti-notch antibodies for therapeutic and diagnostic use
|
|
WO2010141249A2
(en)
|
2009-06-02 |
2010-12-09 |
Merck Sharp & Dohme Corp. |
Generation, characterization and uses thereof of anti-notch3 antibodies
|
|
JP6208580B2
(ja)
|
2010-05-17 |
2017-10-04 |
サンガモ セラピューティクス, インコーポレイテッド |
新規のdna結合タンパク質及びその使用
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
WO2013126726A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Double transgenic t cells comprising a car and a tcr and their methods of use
|
|
EP3241902B1
(en)
|
2012-05-25 |
2018-02-28 |
The Regents of The University of California |
Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
|
|
US10316289B2
(en)
*
|
2012-09-06 |
2019-06-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T memory stem cell populations
|
|
WO2014093718A1
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
|
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
|
US10696946B2
(en)
*
|
2013-02-22 |
2020-06-30 |
The Board Of Trustees Of The University Of Illinois |
T-REG cell expansion
|
|
US9683039B2
(en)
|
2013-03-14 |
2017-06-20 |
New York University |
Notch agonists for the treatment of cancer
|
|
EP3760719A1
(en)
|
2013-11-18 |
2021-01-06 |
CRISPR Therapeutics AG |
Crispr-cas system materials and methods
|
|
KR20170007449A
(ko)
|
2014-05-22 |
2017-01-18 |
프레드 헛친슨 켄서 리서치 센터 |
조혈 전구체 세포의 lilrb2 및 노치 매개 증식
|
|
BR112016028537A2
(pt)
|
2014-06-04 |
2017-08-22 |
Hutchinson Fred Cancer Res |
expansão e enxerto de células-tronco utilizando agonistas de notch 1 e/ou de notch 2
|
|
MX389823B
(es)
*
|
2014-10-27 |
2025-03-20 |
Fred Hutchinson Cancer Center |
Composiciones y metodos para reforzar la eficacia de inmunoterapia celular adoptiva.
|
|
CN108431211B
(zh)
*
|
2015-10-20 |
2026-03-24 |
富士胶片细胞动力公司 |
通过遗传编程的多谱系造血前体细胞产生
|
|
SG11201803330WA
(en)
*
|
2015-10-22 |
2018-05-30 |
Juno Therapeutics Gmbh |
Methods for culturing cells and kits and apparatus for same
|
|
MX2018005274A
(es)
*
|
2015-10-30 |
2019-09-19 |
The Regents Of The Universtiy Of California |
Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.
|
|
JP7049261B2
(ja)
*
|
2016-04-08 |
2022-04-06 |
ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント |
幹細胞および/または前駆細胞からt前駆細胞を作製する方法ならびに該t前駆細胞の使用
|
|
US11261250B2
(en)
|
2016-07-22 |
2022-03-01 |
Fred Hutchinson Cancer Research Center |
Bi-specific molecule for cell-specific Notch inhibition and related methods and compositions
|