JP2021502414A5 - - Google Patents
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- JP2021502414A5 JP2021502414A5 JP2020544357A JP2020544357A JP2021502414A5 JP 2021502414 A5 JP2021502414 A5 JP 2021502414A5 JP 2020544357 A JP2020544357 A JP 2020544357A JP 2020544357 A JP2020544357 A JP 2020544357A JP 2021502414 A5 JP2021502414 A5 JP 2021502414A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- population
- expanded
- complex
- tumor antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022060497A JP7420856B2 (ja) | 2017-11-08 | 2022-03-31 | Ｔ細胞を製造する組成物及び方法 |
| JP2024001623A JP7728373B2 (ja) | 2017-11-08 | 2024-01-10 | Ｔ細胞を製造する組成物及び方法 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762583229P | 2017-11-08 | 2017-11-08 | |
| US62/583,229 | 2017-11-08 | ||
| US201762588590P | 2017-11-20 | 2017-11-20 | |
| US62/588,590 | 2017-11-20 | ||
| US201862618445P | 2018-01-17 | 2018-01-17 | |
| US62/618,445 | 2018-01-17 | ||
| US201862737625P | 2018-09-27 | 2018-09-27 | |
| US62/737,625 | 2018-09-27 | ||
| PCT/US2018/059896 WO2019094642A1 (en) | 2017-11-08 | 2018-11-08 | T cell manufacturing compositions and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022060497A Division JP7420856B2 (ja) | 2017-11-08 | 2022-03-31 | Ｔ細胞を製造する組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021502414A JP2021502414A (ja) | 2021-01-28 |
| JP2021502414A5 true JP2021502414A5 (https=) | 2021-12-16 |
| JP7054418B2 JP7054418B2 (ja) | 2022-04-13 |
Family
ID=66438061
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544357A Active JP7054418B2 (ja) | 2017-11-08 | 2018-11-08 | Ｔ細胞を製造する組成物及び方法 |
| JP2022060497A Active JP7420856B2 (ja) | 2017-11-08 | 2022-03-31 | Ｔ細胞を製造する組成物及び方法 |
| JP2024001623A Active JP7728373B2 (ja) | 2017-11-08 | 2024-01-10 | Ｔ細胞を製造する組成物及び方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022060497A Active JP7420856B2 (ja) | 2017-11-08 | 2022-03-31 | Ｔ細胞を製造する組成物及び方法 |
| JP2024001623A Active JP7728373B2 (ja) | 2017-11-08 | 2024-01-10 | Ｔ細胞を製造する組成物及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US11162072B2 (https=) |
| EP (1) | EP3706784A4 (https=) |
| JP (3) | JP7054418B2 (https=) |
| KR (2) | KR20230008254A (https=) |
| CN (2) | CN120519386A (https=) |
| BR (1) | BR112020008927A2 (https=) |
| CA (1) | CA3081840A1 (https=) |
| SG (1) | SG11202004116QA (https=) |
| WO (1) | WO2019094642A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018187515A1 (en) | 2017-04-04 | 2018-10-11 | Avidea Technologies, Inc. | Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response |
| CA3081840A1 (en) | 2017-11-08 | 2019-05-16 | Neon Therapeutics, Inc. | T cell manufacturing compositions and methods |
| BR112020025764A2 (pt) | 2018-06-19 | 2021-05-11 | Biontech Us Inc. | neoantígenos e usos dos mesmos |
| KR20210040355A (ko) * | 2018-06-19 | 2021-04-13 | 바이오엔테크 유에스 인크. | 네오항원 및 이의 용도 |
| CA3132028A1 (en) | 2019-03-30 | 2020-10-08 | Biontech Us Inc. | Compositions and methods for preparing t cell compositions and uses thereof |
| TWI777160B (zh) * | 2019-05-08 | 2022-09-11 | 美商百歐恩泰美國公司 | T細胞製備組合物及方法 |
| GB201911066D0 (en) | 2019-08-02 | 2019-09-18 | Achilles Therapeutics Ltd | T cell therapy |
| CN110514845B (zh) * | 2019-08-22 | 2022-09-27 | 深圳新合睿恩生物医疗科技有限公司 | 一种肿瘤新生抗原免疫原性检测方法及检测平台 |
| CA3162703A1 (en) * | 2019-11-27 | 2021-06-03 | Myst Therapeutics, Llc | Method of producing tumor-reactive t cell composition using modulatory agents |
| JP2023505726A (ja) | 2019-12-12 | 2023-02-10 | アキレス セラピューティクス ユーケー リミテッド | 配列決定のための核酸を得る方法 |
| GB201918290D0 (en) | 2019-12-12 | 2020-01-29 | Achilles Therapeutics Ltd | Method |
| WO2021219990A1 (en) | 2020-04-28 | 2021-11-04 | Achilles Therapeutics Uk Limited | T cell therapy |
| US12365871B2 (en) | 2020-04-28 | 2025-07-22 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| EP4146794A1 (en) * | 2020-05-04 | 2023-03-15 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| AU2021325082A1 (en) | 2020-08-13 | 2023-04-20 | Biontech Us Inc. | RAS neoantigens and uses thereof |
| US20230374455A1 (en) | 2020-08-13 | 2023-11-23 | Biontech Us Inc. | T cell manufacturing compositions and methods |
| AU2021388167A1 (en) * | 2020-11-25 | 2023-07-06 | Geneius Biotechnology, Inc. | Antigen specific t cells and methods of making and using same |
| MX2023007003A (es) | 2020-12-14 | 2023-08-18 | Biontech Us Inc | Antigenos especificos de tejidos para la inmunoterapia del cancer. |
| EP4320435A1 (en) | 2021-04-09 | 2024-02-14 | Achilles Therapeutics UK Limited | Batch release assay for pharmaceutical products relating to t cell therapies |
| GB202109886D0 (en) | 2021-07-08 | 2021-08-25 | Achilles Therapeutics Uk Ltd | Assay |
| IL312121A (en) * | 2021-10-15 | 2024-06-01 | Biontech Us Inc | T cell manufacturing compositions and methods |
| GB202210006D0 (en) | 2022-07-07 | 2022-08-24 | Achilles Therapeutics Uk Ltd | Analysis of T cell samples |
| AU2024234571A1 (en) * | 2023-03-15 | 2025-09-25 | Gaia Biomedicine Inc. | Solution for suspending cells and use thereof |
| WO2025245492A1 (en) * | 2024-05-24 | 2025-11-27 | Biontech Us Inc. | Compositions and methods for t cell manufacturing and uses thereof |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
| PT633929E (pt) | 1992-04-01 | 2004-07-30 | Merix Bioscience Inc | Metodo para proliferacao (in vitro) de precursores de celulas dentifricas e sua utilizacao para produzir imunogenios |
| AU4998993A (en) | 1992-08-07 | 1994-03-03 | Epimmune, Inc. | Hla binding peptides and their uses |
| CN1118572A (zh) | 1993-03-05 | 1996-03-13 | 萨依特尔有限公司 | Hla-a2.1组合肽及其用途 |
| US5849589A (en) | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| WO2004022709A2 (en) | 2002-09-06 | 2004-03-18 | Mannkind Corporation | Epitope sequences |
| US7276478B2 (en) * | 2003-09-25 | 2007-10-02 | Zymogenetics, Inc. | Methods of treating autoimmune diseases using IL-21 |
| WO2006015497A1 (en) * | 2004-08-13 | 2006-02-16 | Val-Chum, S.E.C. | Methods of use of a dkk1 protein, immunogenic polypeptides thereof, nucleic acid encoding the dkk1 protein or polypeptides, or ligands thereof for detecting tumors; and for eliciting immune response against tumors |
| WO2006110582A1 (en) * | 2005-04-08 | 2006-10-19 | Xcyte Therapies, Inc. | Compositions and methods for the treatment of burns and sepsis |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| ES2579762T3 (es) | 2006-03-01 | 2016-08-16 | Janssen Pharmaceutica N.V. | Tratamiento del cáncer combinando agente linfo - reductor con CLTs y citoquinas |
| US9809797B2 (en) * | 2007-10-03 | 2017-11-07 | National Institutes Of Health (Nih) U.S. Dept. Of Health And Human Services (Dhhs) Division Of Extramural Inventions And Technology | Enhanced generation of cytotoxic T-lymphocytes by IL-21 mediated FOXP3 suppression |
| BR112012029066A2 (pt) | 2010-05-14 | 2020-09-01 | The General Hospital Corporation | composições e processos de identificação de neoantígenos específicos de tumor. |
| WO2012159643A1 (en) | 2011-05-24 | 2012-11-29 | Biontech Ag | Individualized vaccines for cancer |
| EP2749639B1 (en) | 2012-02-10 | 2016-10-12 | Hakushinkouseikai Foundation | Proliferating agent for monocyte, culture medium for proliferating monocyte, method for producing monocyte, method for producing dendritic cell, and method for producing dendritic cell vaccine |
| US20150104441A1 (en) | 2013-10-11 | 2015-04-16 | Oslo Universitetssykehus Hf | Identification of disease-driving antigens |
| EP3082853A2 (en) | 2013-12-20 | 2016-10-26 | The Broad Institute, Inc. | Combination therapy with neoantigen vaccine |
| JP6661544B2 (ja) * | 2014-04-24 | 2020-03-11 | ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 遺伝子改変したｔ細胞の自動生成法 |
| CN103923880B (zh) * | 2014-05-08 | 2016-03-30 | 成都百赛泰科生物科技有限公司 | 一种高效增殖、靶向杀伤肿瘤的ctl制备方法 |
| US10973894B2 (en) | 2014-10-02 | 2021-04-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human | Methods of isolating T cells having antigenic specificity for a cancer-specific mutation |
| WO2016180852A1 (en) * | 2015-05-12 | 2016-11-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for preparing antigen-specific t cells from an umbilical cord blood sample |
| AU2016297014B2 (en) | 2015-07-21 | 2021-06-17 | Novartis Ag | Methods for improving the efficacy and expansion of immune cells |
| AU2016306408B2 (en) | 2015-08-10 | 2021-02-11 | Toray Industries, Inc. | Immune inducer |
| WO2017044661A1 (en) | 2015-09-09 | 2017-03-16 | Immune Design Corp. | Ny-eso-1 specific tcrs and methods of use thereof |
| EP3347051A4 (en) | 2015-09-10 | 2019-04-24 | Affigen, Inc. | SEQUENCING SELECTING TUMOR THEROSTICAS |
| CN109153727A (zh) | 2016-04-15 | 2019-01-04 | 酵活有限公司 | 靶向免疫治疗剂的多特异性抗原结合构建体 |
| EP3446119A1 (en) | 2016-04-18 | 2019-02-27 | The Broad Institute Inc. | Improved hla epitope prediction |
| US11236145B2 (en) | 2017-03-23 | 2022-02-01 | Immatics Biotechnologies Gmbh | T cell receptors and immune therapy using the same against PRAME positive cancers |
| AU2018337960B2 (en) | 2017-09-20 | 2025-08-14 | Neximmune, Inc. | Cell compositions comprising antigen-specific T cells for adoptive therapy |
| CA3081840A1 (en) | 2017-11-08 | 2019-05-16 | Neon Therapeutics, Inc. | T cell manufacturing compositions and methods |
| WO2020047449A2 (en) | 2018-08-31 | 2020-03-05 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| AU2019404547B2 (en) | 2018-12-21 | 2025-01-30 | Biontech Us Inc. | Method and systems for prediction of HLA class II-specific epitopes and characterization of CD4+ T cells |
| TWI777160B (zh) | 2019-05-08 | 2022-09-11 | 美商百歐恩泰美國公司 | T細胞製備組合物及方法 |
| US20230374455A1 (en) | 2020-08-13 | 2023-11-23 | Biontech Us Inc. | T cell manufacturing compositions and methods |
| IL312121A (en) | 2021-10-15 | 2024-06-01 | Biontech Us Inc | T cell manufacturing compositions and methods |
| IL321246A (en) | 2022-12-09 | 2025-08-01 | Biontech Us Inc | Compositions and methods for producing T cells |
-
2018
- 2018-11-08 CA CA3081840A patent/CA3081840A1/en active Pending
- 2018-11-08 KR KR1020227046367A patent/KR20230008254A/ko not_active Ceased
- 2018-11-08 JP JP2020544357A patent/JP7054418B2/ja active Active
- 2018-11-08 KR KR1020207016435A patent/KR102484433B1/ko active Active
- 2018-11-08 CN CN202510236442.4A patent/CN120519386A/zh active Pending
- 2018-11-08 SG SG11202004116QA patent/SG11202004116QA/en unknown
- 2018-11-08 EP EP18875943.5A patent/EP3706784A4/en active Pending
- 2018-11-08 WO PCT/US2018/059896 patent/WO2019094642A1/en not_active Ceased
- 2018-11-08 BR BR112020008927-3A patent/BR112020008927A2/pt unknown
- 2018-11-08 CN CN201880085909.8A patent/CN111867618B/zh active Active
-
2020
- 2020-01-06 US US16/735,555 patent/US11162072B2/en active Active
-
2021
- 2021-10-05 US US17/494,633 patent/US12258581B2/en active Active
-
2022
- 2022-03-31 JP JP2022060497A patent/JP7420856B2/ja active Active
-
2024
- 2024-01-10 JP JP2024001623A patent/JP7728373B2/ja active Active
-
2025
- 2025-01-27 US US19/038,215 patent/US20250188414A1/en active Pending
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