JP2021501596A5 - - Google Patents
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- JP2021501596A5 JP2021501596A5 JP2020524540A JP2020524540A JP2021501596A5 JP 2021501596 A5 JP2021501596 A5 JP 2021501596A5 JP 2020524540 A JP2020524540 A JP 2020524540A JP 2020524540 A JP2020524540 A JP 2020524540A JP 2021501596 A5 JP2021501596 A5 JP 2021501596A5
- Authority
- JP
- Japan
- Prior art keywords
- expansion
- lymphocytes
- interleukin
- apc
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762582163P | 2017-11-06 | 2017-11-06 | |
| US62/582,163 | 2017-11-06 | ||
| PCT/EP2018/080343 WO2019086711A1 (en) | 2017-11-06 | 2018-11-06 | Method for expansion of lymphocytes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021501596A JP2021501596A (ja) | 2021-01-21 |
| JP2021501596A5 true JP2021501596A5 (https=) | 2021-10-28 |
| JP7357613B2 JP7357613B2 (ja) | 2023-10-06 |
Family
ID=64332272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020524540A Active JP7357613B2 (ja) | 2017-11-06 | 2018-11-06 | リンパ球の拡大方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20200338125A1 (https=) |
| EP (1) | EP3707245A1 (https=) |
| JP (1) | JP7357613B2 (https=) |
| CN (1) | CN111801415A (https=) |
| AU (1) | AU2018361561C1 (https=) |
| CA (1) | CA3081479A1 (https=) |
| WO (1) | WO2019086711A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113613725B (zh) | 2018-11-05 | 2025-09-23 | 路德维格癌症研究所有限公司 | 人源化和变体TGF-β1特异性抗体及其方法和用途 |
| EP3877053A1 (en) | 2018-11-05 | 2021-09-15 | Ludwig Institute for Cancer Research Ltd | Humanized and variant tgf-beta3 specific antibodies and methods and uses thereof |
| WO2020263919A1 (en) * | 2019-06-24 | 2020-12-30 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | A peptide-based screening method to identify neoantigens for use with tumor infiltrating lymphocytes |
| JP7337373B2 (ja) * | 2019-07-29 | 2023-09-04 | サイアス株式会社 | 抗原特異的ｔ細胞の製造方法 |
| MX2022007416A (es) * | 2019-12-18 | 2022-09-19 | Cbio As | Proceso mejorado para el cultivo de linfocitos infiltrantes de tumor para uso terapeutico. |
| CA3158133A1 (en) | 2020-04-28 | 2021-11-04 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| EP4159843A4 (en) * | 2020-05-29 | 2024-07-31 | Shanghai Juncell Therapeutics Co., Ltd. | MEDIUM FOR SEEDING CELLS OF TUMOR INFILTRATING LYMPHOCYTES AND ITS APPLICATION |
| AU2021320556A1 (en) | 2020-08-07 | 2023-03-09 | Neogene Therapeutics B.V. | Methods to enrich genetically engineered T cells |
| WO2022040202A1 (en) * | 2020-08-17 | 2022-02-24 | Northwestern University | B-cell based immunotherapy for the treatment of glioblastoma and other cancers |
| EP4239059A4 (en) | 2020-11-19 | 2024-05-15 | Suzhou Grit Biotechnology Co., Ltd. | METHOD FOR CULTIVATION OF TUMOR INFILTRATING LYMPHOCYTES AND USE THEREOF |
| CN112501308B (zh) * | 2020-11-30 | 2025-10-10 | 中国水产科学研究院珠江水产研究所 | 一组鳖科动物线粒体全基因组扩增通用引物 |
| WO2022135525A1 (zh) * | 2020-12-24 | 2022-06-30 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的制备方法及其用途 |
| CN114686430A (zh) * | 2020-12-31 | 2022-07-01 | 上海赛比曼生物科技有限公司 | 一种制备til的方法 |
| TW202242097A (zh) * | 2021-01-20 | 2022-11-01 | 荷蘭商新基因治療公司 | 經工程化之抗原呈現細胞 |
| CN115315509B (zh) * | 2021-02-08 | 2024-05-07 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的制备方法及其用途 |
| JP2024517793A (ja) * | 2021-04-30 | 2024-04-23 | ティゲン・ファーマ・ソシエテ・アノニム | 単一容器リンパ球拡大 |
| US20240207319A1 (en) | 2021-05-06 | 2024-06-27 | Ludwig Institute For Cancer Research Ltd | Compositions and methods for immunotherapy |
| US20240287456A1 (en) * | 2021-06-22 | 2024-08-29 | Achilles Therapeutics Uk Limited | A method for producing antigen-specific t cells |
| CN117616115A (zh) * | 2021-08-03 | 2024-02-27 | 苏州沙砾生物科技有限公司 | 一种修饰的肿瘤浸润淋巴细胞及其用途 |
| EP4405464A4 (en) * | 2021-09-21 | 2025-12-03 | Univ Chicago | METHODS AND COMPOSITION USING PATIENT-DERIVED AUTOLOGOUS NEOANTIGENS FOR CANCER TREATMENT |
| CN115433713B (zh) * | 2022-03-03 | 2023-10-27 | 中山大学孙逸仙纪念医院深汕中心医院 | 一种自体肿瘤引流淋巴结淋巴细胞的制备方法及其应用 |
| WO2024261339A1 (en) | 2023-06-23 | 2024-12-26 | Tigen Pharma Sa | Lymphocyte-stimulatory matrix (lsm) and uses thereof for expansion of lymphocyte populations |
| WO2025081198A1 (en) * | 2023-10-13 | 2025-04-17 | Northwestern University | B cell production and expansion |
| WO2025131119A1 (en) * | 2023-12-22 | 2025-06-26 | Everest Medicines (China) Co., Ltd. | Cancer vaccines and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| US6291430B1 (en) | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| KR20030032922A (ko) | 2000-02-24 | 2003-04-26 | 싸이트 테라피스 인코포레이티드 | 세포의 동시 자극 및 농축 |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| JP5170934B2 (ja) | 2001-08-16 | 2013-03-27 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 改良ｄｎａリポフェクションならびに／または徐放性プロドラッグおよび薬物療法のための試薬の合成と使用 |
| US8034334B2 (en) | 2002-09-06 | 2011-10-11 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy |
| ES2971647T3 (es) | 2005-04-15 | 2024-06-06 | Macrogenics Inc | Diacuerpos covalentes y usos de los mismos |
| US9963510B2 (en) | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| EP1995316A1 (de) | 2007-05-25 | 2008-11-26 | Qiagen GmbH | Verfahren zur schonenden Zellaufreinigung, Zellgewinnung und Transfektion von Zellen |
| EP2009095A1 (en) | 2007-06-28 | 2008-12-31 | Innovalor AG | Method of generating glucose-responsive cells |
| WO2009094273A2 (en) | 2008-01-15 | 2009-07-30 | Yale University | Compositions and methods for adoptive and active immunotherapy |
| CN101824400B (zh) * | 2009-03-05 | 2012-08-08 | 中国科学院微生物研究所 | 一种放大增殖抗原特异性t细胞的方法 |
| US8383099B2 (en) * | 2009-08-28 | 2013-02-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adoptive cell therapy with young T cells |
| EP2569633B1 (en) * | 2010-05-14 | 2016-02-10 | The General Hospital Corporation | Compositions and methods of identifying tumor specific neoantigens |
| WO2012044999A2 (en) | 2010-10-01 | 2012-04-05 | Ludwig Institute For Cancer Research Ltd. | Reversible protein multimers, methods for their production and use |
| KR101749195B1 (ko) * | 2011-12-12 | 2017-06-20 | 셀 메디카 리미티드 | T 세포들을 증식시키는 방법 |
| RU2739770C2 (ru) * | 2014-06-11 | 2020-12-28 | полибайосепт ГмбХ | Экспансия лимфоцитов с использованием композиции цитокинов для активной клеточной иммунотерапии |
| CA3017170C (en) * | 2014-09-17 | 2021-03-23 | The Johns Hopkins University | Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells |
| JP6599450B2 (ja) * | 2014-10-02 | 2019-10-30 | アメリカ合衆国 | がん特異的突然変異に対し抗原特異性を有するｔ細胞を単離する方法 |
| WO2016145578A1 (en) * | 2015-03-13 | 2016-09-22 | Syz Cell Therapy Co. | Methods of cancer treatment using activated t cells |
| EP3452082A1 (en) * | 2016-05-04 | 2019-03-13 | Fred Hutchinson Cancer Research Center | Cell-based neoantigen vaccines and uses thereof |
-
2018
- 2018-11-06 EP EP18804249.3A patent/EP3707245A1/en active Pending
- 2018-11-06 WO PCT/EP2018/080343 patent/WO2019086711A1/en not_active Ceased
- 2018-11-06 AU AU2018361561A patent/AU2018361561C1/en active Active
- 2018-11-06 CN CN201880079423.3A patent/CN111801415A/zh active Pending
- 2018-11-06 JP JP2020524540A patent/JP7357613B2/ja active Active
- 2018-11-06 US US16/761,711 patent/US20200338125A1/en active Pending
- 2018-11-06 CA CA3081479A patent/CA3081479A1/en active Pending
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