JP2021534784A5 - - Google Patents

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Publication number
JP2021534784A5
JP2021534784A5 JP2021510693A JP2021510693A JP2021534784A5 JP 2021534784 A5 JP2021534784 A5 JP 2021534784A5 JP 2021510693 A JP2021510693 A JP 2021510693A JP 2021510693 A JP2021510693 A JP 2021510693A JP 2021534784 A5 JP2021534784 A5 JP 2021534784A5
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JP
Japan
Prior art keywords
isolated polynucleotide
amino acid
cells
seq
sequence identity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021510693A
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English (en)
Japanese (ja)
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JP7627080B2 (ja
JP2021534784A (ja
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Priority claimed from PCT/US2019/048814 external-priority patent/WO2020047257A1/en
Publication of JP2021534784A publication Critical patent/JP2021534784A/ja
Publication of JP2021534784A5 publication Critical patent/JP2021534784A5/ja
Priority to JP2025009061A priority Critical patent/JP2025066785A/ja
Application granted granted Critical
Publication of JP7627080B2 publication Critical patent/JP7627080B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021510693A 2018-08-31 2019-08-29 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物 Active JP7627080B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025009061A JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862725599P 2018-08-31 2018-08-31
US62/725,599 2018-08-31
PCT/US2019/048814 WO2020047257A1 (en) 2018-08-31 2019-08-29 Methods and compositions comprising b7h3 chimeric antigen receptors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025009061A Division JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Publications (3)

Publication Number Publication Date
JP2021534784A JP2021534784A (ja) 2021-12-16
JP2021534784A5 true JP2021534784A5 (enExample) 2023-03-20
JP7627080B2 JP7627080B2 (ja) 2025-02-05

Family

ID=69643750

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021510693A Active JP7627080B2 (ja) 2018-08-31 2019-08-29 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物
JP2025009061A Pending JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Family Applications After (1)

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JP2025009061A Pending JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Country Status (8)

Country Link
US (2) US12173071B2 (enExample)
EP (1) EP3844191A4 (enExample)
JP (2) JP7627080B2 (enExample)
CN (1) CN113039206A (enExample)
AU (1) AU2019333149A1 (enExample)
CA (1) CA3110858A1 (enExample)
IL (1) IL281129A (enExample)
WO (1) WO2020047257A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119504997A (zh) 2021-02-09 2025-02-25 苏州宜联生物医药有限公司 生物活性物偶联物及其制备方法和用途
WO2023155808A1 (zh) 2022-02-16 2023-08-24 苏州宜联生物医药有限公司 抗体-艾日布林或其衍生物的偶联物、其中间体、制备方法、药物组合物和用途
WO2023221975A1 (zh) 2022-05-18 2023-11-23 苏州宜联生物医药有限公司 包含蛋白降解剂类生物活性化合物的抗体药物偶联物及其制备方法和用途
KR20250099721A (ko) * 2022-11-04 2025-07-02 티-맥시멈 파마슈티컬 (수저우) 컴퍼니 리미티드 B7h3을 표적으로 하는 범용형 car-t 세포 및 이의 제조 방법과 응용
WO2024106941A1 (ko) * 2022-11-15 2024-05-23 주식회사 셀랩메드 B7-h3 키메라 항원 수용체 및 이의 용도
KR20260017010A (ko) * 2023-04-24 2026-02-04 엘피스 바이오파마슈티컬즈 장갑 항-b7h3 car-t 세포 및 암 치료에 있어서의 그 용도
WO2025235801A1 (en) 2024-05-08 2025-11-13 City Of Hope Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy
CN119792297B (zh) * 2024-11-11 2026-05-05 中国人民解放军军事科学院军事医学研究院 PNP抑制剂Forodesine在治疗脑肿瘤中的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827642A (en) 1994-08-31 1998-10-27 Fred Hutchinson Cancer Research Center Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
US10155038B2 (en) * 2007-02-02 2018-12-18 Yale University Cells prepared by transient transfection and methods of use thereof
ES2717629T3 (es) 2009-11-03 2019-06-24 Hope City Receptor del factor de crecimiento epidérmico truncado (EGFRt) para selección de células T transducidas
PH12018501083A1 (en) 2010-03-04 2019-02-18 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
PH12012501751A1 (en) * 2010-03-04 2012-11-12 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
PL3824905T3 (pl) 2012-08-20 2025-05-05 Fred Hutchinson Cancer Center Sposób i kompozycje do immunoterapii komórkowej
US9790282B2 (en) * 2013-03-25 2017-10-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD276 polypeptides, proteins, and chimeric antigen receptors
AU2014342020C1 (en) * 2013-10-31 2019-09-05 Fred Hutchinson Cancer Research Center Modified hematopoietic stem/progenitor and non-T effector cells, and uses thereof
AU2015243849B2 (en) 2014-04-10 2020-12-17 Seattle Children's Hospital (dba Seattle Children's Research Institute) Transgene genetic tags and methods of use
JP6985934B2 (ja) * 2015-04-29 2021-12-22 フレッド ハッチンソン キャンサー リサーチ センター 操作された造血幹細胞／前駆細胞及び非ｔエフェクター細胞、ならびにその使用
US10562952B2 (en) 2015-09-10 2020-02-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD276 chimeric antigen receptors
WO2017172981A2 (en) * 2016-03-29 2017-10-05 University Of Southern California Chimeric antigen receptors targeting cancer
US10188749B2 (en) * 2016-04-14 2019-01-29 Fred Hutchinson Cancer Research Center Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
US11326182B2 (en) 2016-04-29 2022-05-10 Voyager Therapeutics, Inc. Compositions for the treatment of disease
IL273961B2 (en) * 2017-10-18 2025-04-01 Precigen Inc Polypeptide compositions containing spacers
US12473344B2 (en) * 2018-07-06 2025-11-18 The Board Of Trustees Of The Leland Stanford Junior University Chimeric antigen receptor polypeptides and methods of using same

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