JP2021530217A5 - - Google Patents
Info
- Publication number
- JP2021530217A5 JP2021530217A5 JP2021500519A JP2021500519A JP2021530217A5 JP 2021530217 A5 JP2021530217 A5 JP 2021530217A5 JP 2021500519 A JP2021500519 A JP 2021500519A JP 2021500519 A JP2021500519 A JP 2021500519A JP 2021530217 A5 JP2021530217 A5 JP 2021530217A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- isolated nucleic
- polypeptide
- cell
- acid according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024022330A JP2024073449A (ja) | 2018-07-10 | 2024-02-16 | Ｒｏｒ－１特異的キメラ抗原受容体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862696075P | 2018-07-10 | 2018-07-10 | |
| US62/696,075 | 2018-07-10 | ||
| PCT/US2019/041213 WO2020014366A1 (en) | 2018-07-10 | 2019-07-10 | Ror-1 specific chimeric antigen receptors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024022330A Division JP2024073449A (ja) | 2018-07-10 | 2024-02-16 | Ｒｏｒ－１特異的キメラ抗原受容体およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021530217A JP2021530217A (ja) | 2021-11-11 |
| JP2021530217A5 true JP2021530217A5 (https=) | 2022-07-12 |
Family
ID=69141807
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021500519A Pending JP2021530217A (ja) | 2018-07-10 | 2019-07-10 | Ｒｏｒ−１特異的キメラ抗原受容体およびその使用 |
| JP2024022330A Pending JP2024073449A (ja) | 2018-07-10 | 2024-02-16 | Ｒｏｒ－１特異的キメラ抗原受容体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024022330A Pending JP2024073449A (ja) | 2018-07-10 | 2024-02-16 | Ｒｏｒ－１特異的キメラ抗原受容体およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12275772B2 (https=) |
| EP (1) | EP3820484A4 (https=) |
| JP (2) | JP2021530217A (https=) |
| KR (1) | KR20210043562A (https=) |
| CN (1) | CN112714769A (https=) |
| AU (1) | AU2019301147B2 (https=) |
| CA (1) | CA3105816A1 (https=) |
| IL (1) | IL280029A (https=) |
| SG (1) | SG11202100205UA (https=) |
| WO (1) | WO2020014366A1 (https=) |
| ZA (1) | ZA202100391B (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| US11771718B2 (en) * | 2017-10-18 | 2023-10-03 | Precigen, Inc. | Polypeptide compositions comprising spacers |
| CA3105816A1 (en) | 2018-07-10 | 2020-01-16 | Precigen, Inc. | Ror-1 specific chimeric antigen receptors and uses thereof |
| JP7632868B2 (ja) * | 2018-10-26 | 2025-02-19 | 国立大学法人信州大学 | 高効率な遺伝子改変細胞の作製方法 |
| WO2021050789A1 (en) | 2019-09-10 | 2021-03-18 | Obsidian Therapeutics, Inc. | Ca2-il15 fusion proteins for tunable regulation |
| WO2021189008A1 (en) | 2020-03-20 | 2021-09-23 | Lyell Immunopharma, Inc. | Novel recombinant cell surface markers |
| CN115916963A (zh) | 2020-03-27 | 2023-04-04 | 门德斯有限公司 | 白血病来源的经修饰细胞用于增强过继性细胞治疗的效力的离体用途 |
| CN113584083A (zh) * | 2020-04-30 | 2021-11-02 | 深圳市深研生物科技有限公司 | 用于逆转录病毒载体的生产细胞和包装细胞及其制备方法 |
| EP4171617A1 (en) | 2020-06-30 | 2023-05-03 | Mendus B.V. | Use of leukemia-derived cells in ovarian cancer vaccines |
| CA3196677A1 (en) | 2020-11-05 | 2022-05-12 | Erik Hans MANTING | Use of tumor-independent antigens in immunotherapies |
| CN116648457A (zh) * | 2020-12-31 | 2023-08-25 | 亘喜生物科技（上海）有限公司 | 膜融合蛋白及其在免疫细胞中的应用 |
| AU2022205683A1 (en) * | 2021-01-11 | 2023-07-06 | Precigen, Inc. | Chimeric receptor therapy |
| JP2024506249A (ja) | 2021-01-22 | 2024-02-13 | メンドゥス・ベスローテン・フェンノートシャップ | 腫瘍ワクチン接種の方法 |
| JP2024505093A (ja) * | 2021-02-01 | 2024-02-02 | ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア | 神経内分泌がんの治療 |
| US12144827B2 (en) | 2021-02-25 | 2024-11-19 | Lyell Immunopharma, Inc. | ROR1 targeting chimeric antigen receptor |
| WO2022188652A1 (zh) * | 2021-03-09 | 2022-09-15 | 四川科伦博泰生物医药股份有限公司 | Ror1结合蛋白及其用途 |
| IL310901A (en) * | 2021-08-18 | 2024-04-01 | Univ Pennsylvania | Compositions and methods for chimeric antigen receptors specific to b cell receptors |
| IL312204A (en) | 2021-10-28 | 2024-06-01 | Lyell Immunopharma Inc | Methods for culturing cells expressing ror1-binding protein |
| IL316226A (en) * | 2022-05-24 | 2024-12-01 | Caribou Biosciences Inc | Anti-ror1 antibody and ror1-targeting engineered cells |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| CN118206620A (zh) * | 2022-12-09 | 2024-06-18 | 上海细胞治疗集团股份有限公司 | 一种多肽标签及其应用 |
| CN116284246B (zh) * | 2022-12-12 | 2025-11-14 | 江苏三联生物工程股份有限公司 | 信号肽、核酸片段、重组表达载体、宿主细胞及其应用 |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| WO2025194140A1 (en) * | 2024-03-15 | 2025-09-18 | Port Therapeutics, Inc. | Thermally controlled gene expression and uses thereof |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| AU734051B2 (en) | 1996-04-05 | 2001-05-31 | Salk Institute For Biological Studies, The | Hormone-mediated methods for modulating expression of exogenous genes in mammalian systems, and products related thereto |
| EP0998560A1 (en) | 1997-07-10 | 2000-05-10 | The Salk Institute For Biological Studies | Modified lepidopteran receptors and hybrid multifunctional proteins for use in regulation of transgene expression |
| US6333318B1 (en) | 1998-05-14 | 2001-12-25 | The Salk Institute For Biological Studies | Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto |
| US9242014B2 (en) * | 2010-06-15 | 2016-01-26 | The Regents Of The University Of California | Receptor tyrosine kinase-like orphan receptor 1 (ROR1) single chain Fv antibody fragment conjugates and methods of use thereof |
| EP3828205A1 (en) * | 2010-10-01 | 2021-06-02 | Oxford BioTherapeutics Ltd | Anti-ror1 antibodies |
| EP3604339B1 (en) * | 2011-01-14 | 2021-03-10 | The Regents Of The University Of California | Therapeutic antibodies against ror-1 protein and methods for use of same |
| JP6189754B2 (ja) * | 2011-03-04 | 2017-08-30 | イントレキソン コーポレーション | タンパク質を条件的に発現するベクター |
| RU2766608C2 (ru) * | 2012-04-11 | 2022-03-15 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток |
| CN104854133B (zh) * | 2012-10-12 | 2018-10-30 | 新加坡科技研究局 | 用于制备重组抗体治疗剂的最佳重链和轻链信号肽 |
| US9657105B2 (en) * | 2013-03-15 | 2017-05-23 | City Of Hope | CD123-specific chimeric antigen receptor redirected T cells and methods of their use |
| EP3783098A1 (en) | 2013-05-14 | 2021-02-24 | Board Of Regents, The University Of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| JP2017501712A (ja) | 2013-12-18 | 2017-01-19 | イントレキソン コーポレーション | 単鎖ｉｌ−１２核酸、ポリペプチド、およびそれらの使用 |
| WO2016016344A1 (en) * | 2014-07-29 | 2016-02-04 | Cellectis | Ror1(ntrkr1)specific chimeric antigen receptors for cancer immunotherapy |
| US10544201B2 (en) * | 2014-07-31 | 2020-01-28 | Cellectis | ROR1 specific multi-chain chimeric antigen receptor |
| EP3197911A4 (en) | 2014-09-22 | 2018-06-20 | Intrexon Corporation | Improved therapeutic control of heterodimeric and single chain forms of interleukin-12 |
| ES2818103T3 (es) * | 2015-01-16 | 2021-04-09 | Juno Therapeutics Inc | Anticuerpos y receptores de antígenos quiméricos específicos para ROR1 |
| WO2016187216A1 (en) * | 2015-05-18 | 2016-11-24 | Bluebird Bio, Inc. | Anti-ror1 chimeric antigen receptors |
| WO2017062953A1 (en) | 2015-10-10 | 2017-04-13 | Intrexon Corporation | Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12 |
| CA3012344A1 (en) | 2016-02-12 | 2017-08-17 | University Of Massachusetts | Anti-angiogenic mirna therapeutics for inhibiting corneal neovascularization |
| KR20230148844A (ko) * | 2016-03-29 | 2023-10-25 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
| CA3025667A1 (en) * | 2016-06-08 | 2017-12-14 | Intrexon Corporation | Cd33 specific chimeric antigen receptors |
| KR20190090390A (ko) * | 2016-11-30 | 2019-08-01 | 인트렉손 코포레이션 | 스테로이드 투여 및 면역요법 |
| US11408005B2 (en) * | 2016-12-12 | 2022-08-09 | Seattle Children's Hospital | Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells |
| EP3568474A1 (en) * | 2017-01-10 | 2019-11-20 | Intrexon Corporation | Modulating expression of polypeptides via new gene switch expression systems |
| CA3065930A1 (en) | 2017-06-07 | 2018-12-13 | Intrexon Corporation | Expression of novel cell tags |
| US11771718B2 (en) | 2017-10-18 | 2023-10-03 | Precigen, Inc. | Polypeptide compositions comprising spacers |
| US11649455B2 (en) | 2018-03-30 | 2023-05-16 | University Of Geneva | Micro RNA expression constructs and uses thereof |
| CA3105816A1 (en) | 2018-07-10 | 2020-01-16 | Precigen, Inc. | Ror-1 specific chimeric antigen receptors and uses thereof |
-
2019
- 2019-07-10 CA CA3105816A patent/CA3105816A1/en active Pending
- 2019-07-10 AU AU2019301147A patent/AU2019301147B2/en active Active
- 2019-07-10 KR KR1020217002650A patent/KR20210043562A/ko not_active Ceased
- 2019-07-10 CN CN201980059126.7A patent/CN112714769A/zh active Pending
- 2019-07-10 WO PCT/US2019/041213 patent/WO2020014366A1/en not_active Ceased
- 2019-07-10 EP EP19833113.4A patent/EP3820484A4/en active Pending
- 2019-07-10 JP JP2021500519A patent/JP2021530217A/ja active Pending
- 2019-07-10 SG SG11202100205UA patent/SG11202100205UA/en unknown
-
2021
- 2021-01-07 IL IL280029A patent/IL280029A/en unknown
- 2021-01-07 US US17/143,386 patent/US12275772B2/en active Active
- 2021-01-19 ZA ZA2021/00391A patent/ZA202100391B/en unknown
-
2024
- 2024-02-16 JP JP2024022330A patent/JP2024073449A/ja active Pending
-
2025
- 2025-03-12 US US19/077,365 patent/US20260035432A1/en active Pending
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