JP2021520813A5 - - Google Patents

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Publication number
JP2021520813A5
JP2021520813A5 JP2020555518A JP2020555518A JP2021520813A5 JP 2021520813 A5 JP2021520813 A5 JP 2021520813A5 JP 2020555518 A JP2020555518 A JP 2020555518A JP 2020555518 A JP2020555518 A JP 2020555518A JP 2021520813 A5 JP2021520813 A5 JP 2021520813A5
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JP
Japan
Prior art keywords
cell
cells
nucleic acid
chimeric receptor
acid molecule
Prior art date
Application number
JP2020555518A
Other languages
English (en)
Japanese (ja)
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JP7562417B2 (ja
JP2021520813A (ja
JPWO2019199165A5 (https=
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Priority claimed from PCT/NL2019/050212 external-priority patent/WO2019199165A1/en
Publication of JP2021520813A publication Critical patent/JP2021520813A/ja
Publication of JP2021520813A5 publication Critical patent/JP2021520813A5/ja
Publication of JPWO2019199165A5 publication Critical patent/JPWO2019199165A5/ja
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Publication of JP7562417B2 publication Critical patent/JP7562417B2/ja
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JP2020555518A 2018-04-10 2019-04-10 キメラノッチ受容体 Active JP7562417B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18166498.8 2018-04-10
EP18166498 2018-04-10
PCT/NL2019/050212 WO2019199165A1 (en) 2018-04-10 2019-04-10 Chimeric notch receptors

Publications (4)

Publication Number Publication Date
JP2021520813A JP2021520813A (ja) 2021-08-26
JP2021520813A5 true JP2021520813A5 (https=) 2022-04-19
JPWO2019199165A5 JPWO2019199165A5 (https=) 2022-04-19
JP7562417B2 JP7562417B2 (ja) 2024-10-07

Family

ID=62063276

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020555518A Active JP7562417B2 (ja) 2018-04-10 2019-04-10 キメラノッチ受容体

Country Status (9)

Country Link
US (1) US20210139556A1 (https=)
EP (1) EP3774867A1 (https=)
JP (1) JP7562417B2 (https=)
KR (1) KR20210008840A (https=)
CN (1) CN112243442A (https=)
AU (1) AU2019252878B2 (https=)
CA (1) CA3096812A1 (https=)
IL (1) IL277859A (https=)
WO (1) WO2019199165A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116790647B (zh) * 2023-02-06 2024-04-16 森瑞斯生物科技(深圳)有限公司 一种低背景、高信号强度的2-吡咯烷酮生物传感器及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047878A1 (en) * 2004-11-03 2006-05-11 British Columbia Cancer Agency Branch Cancer therapeutics and methods for their use
CN104402998A (zh) * 2008-07-08 2015-03-11 昂考梅德药品有限公司 分离的抗体
SG191039A1 (en) * 2010-12-15 2013-08-30 Wyeth Llc Anti-notch1 antibodies
EP2970479B1 (en) * 2013-03-14 2019-04-24 Novartis AG Antibodies against notch 3
BR112016028537A2 (pt) * 2014-06-04 2017-08-22 Hutchinson Fred Cancer Res expansão e enxerto de células-tronco utilizando agonistas de notch 1 e/ou de notch 2
FR3026744B1 (fr) * 2014-10-06 2024-04-19 Hopitaux Paris Assist Publique Methode de generation de progeniteurs de cellules t
WO2016138034A1 (en) * 2015-02-24 2016-09-01 The Regents Of The University Of California Binding-triggered transcriptional switches and methods of use thereof
WO2017123559A2 (en) * 2016-01-11 2017-07-20 The Board Of Trustees Of The Leland Stanford Junior University Chimeric proteins and methods of regulating gene expression
JP7500195B2 (ja) * 2016-08-23 2024-06-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア タンパク質分解により切断可能なキメラポリペプチド及びそれらの使用方法
US11325957B2 (en) * 2017-06-19 2022-05-10 Cell Design Labs, Inc. Methods and compositions for reducing the immunogenicity of chimeric notch receptors

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Asano et al. Multimerization of anti‐(epidermal growth factor receptor) IgG fragments induces an antitumor effect: the case for humanized 528 scFv multimers
Agaugue et al. The high expression of NKG2D ligands on tumor and the lack of surface expression on healthy tissues provides a strong rationale to support NKG2D-based therapeutic approaches for cancer
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