JP2021512614A5 - - Google Patents

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Publication number
JP2021512614A5
JP2021512614A5 JP2020542380A JP2020542380A JP2021512614A5 JP 2021512614 A5 JP2021512614 A5 JP 2021512614A5 JP 2020542380 A JP2020542380 A JP 2020542380A JP 2020542380 A JP2020542380 A JP 2020542380A JP 2021512614 A5 JP2021512614 A5 JP 2021512614A5
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JP
Japan
Prior art keywords
cells
seq
adhesion receptor
target cell
receptor
Prior art date
Application number
JP2020542380A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019155286A5 (https=
JP2021512614A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/000141 external-priority patent/WO2019155286A2/en
Publication of JP2021512614A publication Critical patent/JP2021512614A/ja
Publication of JP2021512614A5 publication Critical patent/JP2021512614A5/ja
Publication of JPWO2019155286A5 publication Critical patent/JPWO2019155286A5/ja
Pending legal-status Critical Current

Links

JP2020542380A 2018-02-09 2019-02-07 ナチュラルキラー細胞免疫療法における接着受容体構築物及びその使用 Pending JP2021512614A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862628797P 2018-02-09 2018-02-09
US62/628,797 2018-02-09
US201862736965P 2018-09-26 2018-09-26
US62/736,965 2018-09-26
PCT/IB2019/000141 WO2019155286A2 (en) 2018-02-09 2019-02-07 Adhesion receptor constructs and uses thereof in natural killer cell immunotherapy

Publications (3)

Publication Number Publication Date
JP2021512614A JP2021512614A (ja) 2021-05-20
JP2021512614A5 true JP2021512614A5 (https=) 2022-02-09
JPWO2019155286A5 JPWO2019155286A5 (https=) 2022-02-09

Family

ID=67548047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542380A Pending JP2021512614A (ja) 2018-02-09 2019-02-07 ナチュラルキラー細胞免疫療法における接着受容体構築物及びその使用

Country Status (8)

Country Link
US (1) US20210054409A1 (https=)
EP (1) EP3749686A4 (https=)
JP (1) JP2021512614A (https=)
CN (1) CN111712516A (https=)
AU (1) AU2019219452A1 (https=)
CA (1) CA3089167A1 (https=)
SG (1) SG11202007183PA (https=)
WO (1) WO2019155286A2 (https=)

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Publication number Priority date Publication date Assignee Title
AU2015259877B2 (en) 2014-05-15 2021-02-25 National University Of Singapore Modified natural killer cells and uses thereof
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
KR102660336B1 (ko) 2017-03-27 2024-04-26 내셔널 유니버시티 오브 싱가포르 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
MX2019011570A (es) 2017-03-27 2019-11-18 Nat Univ Singapore Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
AU2019219454A1 (en) 2018-02-09 2020-08-27 National University Of Singapore Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
CN112055717B (zh) 2018-04-02 2024-04-26 新加坡国立大学 用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
US12590148B2 (en) 2018-11-26 2026-03-31 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
CN110396131B (zh) * 2019-08-23 2020-07-10 北京鼎成肽源生物技术有限公司 一种ErbB2单链抗体、靶向人ErbB2的嵌合抗原受体、重组载体、重组细胞和应用
CA3150224A1 (en) 2019-09-10 2021-03-18 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
CN115197326B (zh) * 2022-06-27 2025-05-16 安徽医科大学第一附属医院 融合蛋白及其编码基因和重组载体以及它们的应用
CN116554300B (zh) * 2023-04-27 2023-10-24 湖北医药学院 一种能与艰难拟梭菌毒素TcdB相互作用的多肽及其应用
CN120098148B (zh) * 2025-05-09 2025-07-22 四川康德赛医疗科技有限公司 一种工程化巨噬细胞制备及抗纤维化的应用

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US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
CA2782333C (en) * 2009-12-02 2019-06-04 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
EP2948544A4 (en) * 2013-01-28 2016-08-03 St Jude Childrens Res Hospital CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
AU2015259877B2 (en) * 2014-05-15 2021-02-25 National University Of Singapore Modified natural killer cells and uses thereof
EP3157958B1 (en) * 2014-06-18 2020-05-06 Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus Car-expressing nk-92 cells as cell therapeutic agents
WO2017027325A1 (en) * 2015-08-07 2017-02-16 Imaginab, Inc. Antigen binding constructs to target molecules
EP4074731A1 (en) * 2015-11-04 2022-10-19 City of Hope Chimeric antigen receptors targeting her2
SG11201810640RA (en) * 2016-06-08 2018-12-28 Intrexon Corp Cd33 specific chimeric antigen receptors
KR102660336B1 (ko) * 2017-03-27 2024-04-26 내셔널 유니버시티 오브 싱가포르 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도

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