JP2021512614A5 - - Google Patents

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Publication number
JP2021512614A5
JP2021512614A5 JP2020542380A JP2020542380A JP2021512614A5 JP 2021512614 A5 JP2021512614 A5 JP 2021512614A5 JP 2020542380 A JP2020542380 A JP 2020542380A JP 2020542380 A JP2020542380 A JP 2020542380A JP 2021512614 A5 JP2021512614 A5 JP 2021512614A5
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JP
Japan
Prior art keywords
cells
seq
adhesion receptor
target cell
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020542380A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021512614A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/000141 external-priority patent/WO2019155286A2/en
Publication of JP2021512614A publication Critical patent/JP2021512614A/ja
Publication of JP2021512614A5 publication Critical patent/JP2021512614A5/ja
Pending legal-status Critical Current

Links

JP2020542380A 2018-02-09 2019-02-07 ナチュラルキラー細胞免疫療法における接着受容体構築物及びその使用 Pending JP2021512614A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862628797P 2018-02-09 2018-02-09
US62/628,797 2018-02-09
US201862736965P 2018-09-26 2018-09-26
US62/736,965 2018-09-26
PCT/IB2019/000141 WO2019155286A2 (en) 2018-02-09 2019-02-07 Adhesion receptor constructs and uses thereof in natural killer cell immunotherapy

Publications (2)

Publication Number Publication Date
JP2021512614A JP2021512614A (ja) 2021-05-20
JP2021512614A5 true JP2021512614A5 (https=) 2022-02-09

Family

ID=67548047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542380A Pending JP2021512614A (ja) 2018-02-09 2019-02-07 ナチュラルキラー細胞免疫療法における接着受容体構築物及びその使用

Country Status (8)

Country Link
US (1) US20210054409A1 (https=)
EP (1) EP3749686A4 (https=)
JP (1) JP2021512614A (https=)
CN (1) CN111712516A (https=)
AU (1) AU2019219452A1 (https=)
CA (1) CA3089167A1 (https=)
SG (1) SG11202007183PA (https=)
WO (1) WO2019155286A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3143134T3 (da) 2014-05-15 2021-01-04 Nat Univ Singapore Modificerede, naturlige dræberceller og anvendelser deraf
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
BR112019019917A2 (pt) 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
CA3056591A1 (en) 2017-03-27 2018-10-04 National University Of Singapore Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
EP3749685A4 (en) 2018-02-09 2021-12-22 National University of Singapore ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY
JP7334985B2 (ja) 2018-04-02 2023-08-29 ナショナル ユニヴァーシティー オブ シンガポール 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
CA3120563A1 (en) 2018-11-26 2020-06-04 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
CN110396131B (zh) * 2019-08-23 2020-07-10 北京鼎成肽源生物技术有限公司 一种ErbB2单链抗体、靶向人ErbB2的嵌合抗原受体、重组载体、重组细胞和应用
WO2021050789A1 (en) 2019-09-10 2021-03-18 Obsidian Therapeutics, Inc. Ca2-il15 fusion proteins for tunable regulation
CN115197326B (zh) * 2022-06-27 2025-05-16 安徽医科大学第一附属医院 融合蛋白及其编码基因和重组载体以及它们的应用
CN116554300B (zh) * 2023-04-27 2023-10-24 湖北医药学院 一种能与艰难拟梭菌毒素TcdB相互作用的多肽及其应用
CN120098148B (zh) * 2025-05-09 2025-07-22 四川康德赛医疗科技有限公司 一种工程化巨噬细胞制备及抗纤维化的应用

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
AU2010325969B2 (en) * 2009-12-02 2016-10-20 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen
EP2948544A4 (en) * 2013-01-28 2016-08-03 St Jude Childrens Res Hospital CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
DK3143134T3 (da) * 2014-05-15 2021-01-04 Nat Univ Singapore Modificerede, naturlige dræberceller og anvendelser deraf
ES2806776T3 (es) * 2014-06-18 2021-02-18 Chemotherapeutisches Forschungsinstitut Georg Speyer Haus Células NK-92 que expresan CAR como agentes terapéuticos celulares
US11254744B2 (en) * 2015-08-07 2022-02-22 Imaginab, Inc. Antigen binding constructs to target molecules
KR20180083874A (ko) * 2015-11-04 2018-07-23 사울 제이. 프라이스맨 Her2를 표적화하는 키메라 항원 수용체
CA3025667A1 (en) * 2016-06-08 2017-12-14 Intrexon Corporation Cd33 specific chimeric antigen receptors
BR112019019917A2 (pt) * 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais

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