JP2024514308A5 - - Google Patents

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Publication number
JP2024514308A5
JP2024514308A5 JP2023560349A JP2023560349A JP2024514308A5 JP 2024514308 A5 JP2024514308 A5 JP 2024514308A5 JP 2023560349 A JP2023560349 A JP 2023560349A JP 2023560349 A JP2023560349 A JP 2023560349A JP 2024514308 A5 JP2024514308 A5 JP 2024514308A5
Authority
JP
Japan
Prior art keywords
nucleic acid
acid molecule
domain
molecule according
variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023560349A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024514308A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/022575 external-priority patent/WO2022212525A2/en
Publication of JP2024514308A publication Critical patent/JP2024514308A/ja
Publication of JP2024514308A5 publication Critical patent/JP2024514308A5/ja
Pending legal-status Critical Current

Links

JP2023560349A 2021-03-30 2022-03-30 CAR T細胞療法及びIFNγ Pending JP2024514308A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163168210P 2021-03-30 2021-03-30
US63/168,210 2021-03-30
PCT/US2022/022575 WO2022212525A2 (en) 2021-03-30 2022-03-30 Car t cell therapy and ifn gamma

Publications (2)

Publication Number Publication Date
JP2024514308A JP2024514308A (ja) 2024-04-01
JP2024514308A5 true JP2024514308A5 (https=) 2025-04-08

Family

ID=81384825

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023560349A Pending JP2024514308A (ja) 2021-03-30 2022-03-30 CAR T細胞療法及びIFNγ

Country Status (5)

Country Link
US (1) US20240366662A1 (https=)
EP (1) EP4314040A2 (https=)
JP (1) JP2024514308A (https=)
CN (1) CN117242090A (https=)
WO (1) WO2022212525A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025235801A1 (en) 2024-05-08 2025-11-13 City Of Hope Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2331566B1 (en) * 2008-08-26 2015-10-07 City of Hope Method and compositions for enhanced anti-tumor effector functioning of t cells
CN113307880B (zh) * 2014-01-13 2025-07-04 希望之城公司 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法
BR112017005631A2 (pt) 2014-09-19 2018-06-26 City Of Hope células t com receptor de antígeno coestimulador quimérico direcionadas à il13ra2
KR102558502B1 (ko) * 2014-12-05 2023-07-20 시티 오브 호프 Cs1 표적화된 키메라 항원 수용체-변형된 t 세포
EP3359574B1 (en) 2015-10-06 2020-04-22 City of Hope Chimeric antigen receptors targeted to psca
IL302560B2 (en) * 2015-10-13 2025-08-01 Hope City Chimeric antigen receptors containing a chlorotoxin domain
KR20180083874A (ko) 2015-11-04 2018-07-23 사울 제이. 프라이스맨 Her2를 표적화하는 키메라 항원 수용체
IL287889B2 (en) * 2016-02-05 2024-03-01 Hope City Administration of engineered t cells for treatment of cancers in the central nervous system
EP3743445A1 (en) * 2018-01-26 2020-12-02 City of Hope Chimeric antigen receptors and methods for reducing off target toxicity
WO2020028275A1 (en) * 2018-07-30 2020-02-06 The Board Of Trustees Of The Leland Stanford Junior University Interferon-gamma biased agonists
EP3830133A1 (en) * 2018-08-01 2021-06-09 City of Hope Tag72 targeted chimeric antigen receptor modified t cells for treatment of tag72-positive tumors
US10918667B2 (en) * 2018-11-20 2021-02-16 Innovative Cellular Therapeutics CO., LTD. Modified cell expressing therapeutic agent and uses thereof
CN119776440A (zh) * 2020-03-09 2025-04-08 成都臻愈生物医药科技有限公司 IFN-γ在制备抗肿瘤辅助药物中的应用
CA3175123A1 (en) * 2020-03-12 2021-09-16 City Of Hope Targeted chimeric antigen receptor modified t cells for treatment of il13r.alpha.2 positive malignancies

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