JP2021526823A5 - - Google Patents

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Publication number
JP2021526823A5
JP2021526823A5 JP2020568694A JP2020568694A JP2021526823A5 JP 2021526823 A5 JP2021526823 A5 JP 2021526823A5 JP 2020568694 A JP2020568694 A JP 2020568694A JP 2020568694 A JP2020568694 A JP 2020568694A JP 2021526823 A5 JP2021526823 A5 JP 2021526823A5
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modified oligonucleotide
modified
compound according
oligomer compound
nucleic acid
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JP2020568694A
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JP2021526823A (ja
JP7557378B2 (ja
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Priority claimed from PCT/US2019/037215 external-priority patent/WO2019241648A1/en
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Priority to JP2024158702A priority Critical patent/JP2025000690A/ja
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JP2020568694A 2018-06-14 2019-06-14 Ｓｔｍｎ２発現を増加させるための化合物及び方法 Active JP7557378B2 (ja)

Priority Applications (1)

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JP2024158702A JP2025000690A (ja) 2018-06-14 2024-09-13 Ｓｔｍｎ２発現を増加させるための化合物及び方法

Applications Claiming Priority (3)

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US201862685192P 2018-06-14 2018-06-14
US62/685,192 2018-06-14
PCT/US2019/037215 WO2019241648A1 (en) 2018-06-14 2019-06-14 Compounds and methods for increasing stmn2 expression

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Publications (3)

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JP2021526823A JP2021526823A (ja) 2021-10-11
JP2021526823A5 true JP2021526823A5 (enExample) 2022-06-22
JP7557378B2 JP7557378B2 (ja) 2024-09-27

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JP2024158702A Pending JP2025000690A (ja) 2018-06-14 2024-09-13 Ｓｔｍｎ２発現を増加させるための化合物及び方法

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US (2) US11833168B2 (enExample)
EP (1) EP3807411A4 (enExample)
JP (2) JP7557378B2 (enExample)
AU (1) AU2019287635B2 (enExample)
CA (1) CA3103429A1 (enExample)
WO (1) WO2019241648A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202006528XA (en) 2018-01-12 2020-08-28 Bristol Myers Squibb Co Antisense oligonucleotides targeting alpha-synuclein and uses thereof
CN120310791A (zh) 2018-01-12 2025-07-15 百时美施贵宝公司 靶向α-突触核蛋白的反义寡核苷酸及其用途
CA3103429A1 (en) 2018-06-14 2019-12-19 Don W. Cleveland Compounds and methods for increasing stmn2 expression
CA3126918A1 (en) * 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
EP3976010A4 (en) * 2019-06-03 2023-08-02 Quralis Corporation Oligonucleotides and methods of use for treating neurological diseases
WO2021076964A1 (en) * 2019-10-17 2021-04-22 Icahn School Of Medicine At Mount Sinai Stathmin 2 (stmn2) as a therapeutic target for parkinson's disease
EP4127172A4 (en) * 2020-03-25 2025-06-04 President and Fellows of Harvard College Methods and compositions for restoring STMN2 levels
EP4162051A4 (en) * 2020-06-03 2025-07-09 Quralis Corp TREATMENT OF NEUROLOGICAL DISEASES USING GENE TRANSCRIPT MODULATORS
CN116528878A (zh) * 2020-06-03 2023-08-01 奎里斯公司 使用基因转录物调控剂治疗神经学疾病
JP2023534557A (ja) * 2020-07-23 2023-08-09 エフ． ホフマン－ラ ロシュ アーゲー Ｒｎａ結合タンパク質部位を標的とするオリゴヌクレオチド
WO2022018155A1 (en) 2020-07-23 2022-01-27 F. Hoffmann-La Roche Ag Lna oligonucleotides for splice modulation of stmn2
WO2023222858A1 (en) 2022-05-18 2023-11-23 F. Hoffmann-La Roche Ag Improved oligonucleotides targeting rna binding protein sites

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