JP2024540537A5 - - Google Patents

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Publication number
JP2024540537A5
JP2024540537A5 JP2024529579A JP2024529579A JP2024540537A5 JP 2024540537 A5 JP2024540537 A5 JP 2024540537A5 JP 2024529579 A JP2024529579 A JP 2024529579A JP 2024529579 A JP2024529579 A JP 2024529579A JP 2024540537 A5 JP2024540537 A5 JP 2024540537A5
Authority
JP
Japan
Prior art keywords
nucleic acid
oligomer compound
modified oligonucleotide
modified
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529579A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540537A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/080113 external-priority patent/WO2023092057A1/en
Publication of JP2024540537A publication Critical patent/JP2024540537A/ja
Publication of JP2024540537A5 publication Critical patent/JP2024540537A5/ja
Pending legal-status Critical Current

Links

JP2024529579A 2021-11-18 2022-11-18 プログラニュリン発現を調節するための化合物及び方法 Pending JP2024540537A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163281057P 2021-11-18 2021-11-18
US63/281,057 2021-11-18
PCT/US2022/080113 WO2023092057A1 (en) 2021-11-18 2022-11-18 Compounds and methods for modulating progranulin expression

Publications (2)

Publication Number Publication Date
JP2024540537A JP2024540537A (ja) 2024-10-31
JP2024540537A5 true JP2024540537A5 (enExample) 2025-11-06

Family

ID=86397858

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529579A Pending JP2024540537A (ja) 2021-11-18 2022-11-18 プログラニュリン発現を調節するための化合物及び方法

Country Status (4)

Country Link
US (1) US20250109396A1 (enExample)
EP (1) EP4433591A1 (enExample)
JP (1) JP2024540537A (enExample)
WO (1) WO2023092057A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024321134A1 (en) 2023-08-10 2026-02-19 Harness Therapeutics Limited Functional nucleic acid
WO2025104638A1 (en) * 2023-11-17 2025-05-22 Universita' Degli Studi Di Brescia Antisense oligonucleotides for modulation of progranulin splicing
GB202401412D0 (en) 2024-02-02 2024-03-20 Harness Therapeutics Ltd Functional nucleic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007284651B2 (en) * 2006-08-09 2014-03-20 Institute For Systems Biology Organ-specific proteins and methods of their use
CN106967799A (zh) * 2017-03-24 2017-07-21 杭州艾迪康医学检验中心有限公司 检测btk基因突变的方法、寡核苷酸及其应用
US12595479B2 (en) * 2019-03-20 2026-04-07 President And Fellows Of Harvard College Antisense oligonucleotide-based progranulin augmentation therapy in neurodegenerative diseases
WO2021229036A1 (en) * 2020-05-13 2021-11-18 F. Hoffmann-La Roche Ag Oligonucleotide agonists targeting progranulin

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