JP2021525746A5 - - Google Patents

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Publication number
JP2021525746A5
JP2021525746A5 JP2020566737A JP2020566737A JP2021525746A5 JP 2021525746 A5 JP2021525746 A5 JP 2021525746A5 JP 2020566737 A JP2020566737 A JP 2020566737A JP 2020566737 A JP2020566737 A JP 2020566737A JP 2021525746 A5 JP2021525746 A5 JP 2021525746A5
Authority
JP
Japan
Prior art keywords
composition
subject
food
sepiapterin
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020566737A
Other languages
English (en)
Japanese (ja)
Other versions
JP7547215B2 (ja
JP2021525746A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/034515 external-priority patent/WO2019232126A1/en
Publication of JP2021525746A publication Critical patent/JP2021525746A/ja
Publication of JP2021525746A5 publication Critical patent/JP2021525746A5/ja
Priority to JP2024146283A priority Critical patent/JP7855033B2/ja
Application granted granted Critical
Publication of JP7547215B2 publication Critical patent/JP7547215B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020566737A 2018-05-30 2019-05-30 テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法 Active JP7547215B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024146283A JP7855033B2 (ja) 2018-05-30 2024-08-28 テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862677926P 2018-05-30 2018-05-30
US62/677,926 2018-05-30
US201862771397P 2018-11-26 2018-11-26
US62/771,397 2018-11-26
US201962822365P 2019-03-22 2019-03-22
US62/822,365 2019-03-22
GC2019-37662 2019-05-28
GC201937662 2019-05-28
PCT/US2019/034515 WO2019232126A1 (en) 2018-05-30 2019-05-30 Compositions and methods for increasing tetrahydrobiopterin plasma exposure

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024146283A Division JP7855033B2 (ja) 2018-05-30 2024-08-28 テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2021525746A JP2021525746A (ja) 2021-09-27
JP2021525746A5 true JP2021525746A5 (enExample) 2022-06-03
JP7547215B2 JP7547215B2 (ja) 2024-09-09

Family

ID=68699016

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020566737A Active JP7547215B2 (ja) 2018-05-30 2019-05-30 テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法

Country Status (10)

Country Link
US (2) US12257252B2 (enExample)
EP (1) EP3801534B1 (enExample)
JP (1) JP7547215B2 (enExample)
CN (1) CN112654356A (enExample)
BR (1) BR112020024329A2 (enExample)
CA (1) CA3102105A1 (enExample)
DK (1) DK3801534T3 (enExample)
FI (1) FI3801534T3 (enExample)
MX (1) MX2020012980A (enExample)
WO (1) WO2019232126A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA46973A (fr) 2016-11-29 2019-10-09 Censa Pharmaceuticals Inc Polymorphes de sépiaptérine et leurs sels
MA46972A (fr) 2016-11-29 2019-10-09 Censa Pharmaceuticals Inc Forme polymorphe de sépiaptérine
JP7811085B2 (ja) 2017-09-01 2026-02-04 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピアプテリンを含む医薬組成物及びその使用
FI3801536T3 (fi) * 2018-05-30 2024-08-29 Ptc Therapeutics Mp Inc Sepiapteriinin antaminen ilman ruokaa käytettäväksi menetelmässä sepiapteriinin plasma-altistuksen lisäämiseksi
EP3801534B1 (en) 2018-05-30 2026-02-18 PTC Therapeutics MP, Inc. Treatment of phenylketonuria with sepiapterin
EP4093405A1 (en) * 2020-01-24 2022-11-30 PTC Therapeutics MP, Inc. Methods for treating parkinson's disease with sepiapterin

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WO2005048926A2 (en) 2003-11-13 2005-06-02 The General Hospital Corporation Methods for treating pain
PL1708690T3 (pl) 2003-11-17 2017-01-31 Biomarin Pharmaceutical Inc. Leczenie fenyloketonurii za pomocą BH4
JP5184783B2 (ja) 2003-11-17 2013-04-17 バイオマリン ファーマシューティカル インコーポレイテッド テトラヒドロビオプテリン、及びテトラヒドロビオプテリン類似体の製造方法
EP1687308B1 (en) 2003-11-17 2019-06-12 Merck & Cie Process for preparating (6R)-L-erythrotetrahydrobiopterin hydrochloride crystalline form B from other crystalline forms
KR20070084270A (ko) 2004-11-17 2007-08-24 바이오마린 파머수티컬 인크. 안정한 정제 제형물
JP2008523090A (ja) 2004-12-08 2008-07-03 バイオマリン ファーマシューティカル インコーポレイテッド 新生児肺高血圧症の治療のための方法および組成物
BRPI0609421B1 (pt) 2005-04-28 2021-06-01 Shiratori Pharmaceutical Co., Ltd. Processos para produção de um composto 1,1-bis-alquil sulfonila, para produção de um composto aldeído, e para produção de um derivado de hidrazona
US20080075666A1 (en) 2006-08-25 2008-03-27 Dudley Samuel C Jr Methods and compositions for treating diastolic dysfunction
LT2545939T (lt) 2007-04-11 2021-03-10 Biomarin Pharmaceutical Inc. Tetrahidrobiopterinas, skirtas gydyti ligas, susijusias supadidėjusiu fenilalanino kiekiu
WO2010017570A2 (de) 2008-08-12 2010-02-18 Orpha Swiss Gmbh Pharmazeutische darreichungsform enthaltend tetrahydrobiopterin
EP2562176B1 (en) 2010-04-22 2018-08-15 Nihon University Medicinal agent and beverage/food for preventing cerebral dysfunction and improving same
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
CN103458900A (zh) * 2011-03-01 2013-12-18 鲁必康研究私人有限公司 四氢生物蝶呤的稳定组合物
US9216178B2 (en) * 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
CN104736539B (zh) 2012-05-07 2017-09-01 白鸟制药株式会社 墨蝶呤和四氢乳酰蝶呤的制造法
EP3213062B1 (en) 2014-10-31 2020-02-12 Children's Medical Center Corporation Methods and assays relating to sepiapterin reductase inhibition
MA46972A (fr) 2016-11-29 2019-10-09 Censa Pharmaceuticals Inc Forme polymorphe de sépiaptérine
MA46973A (fr) 2016-11-29 2019-10-09 Censa Pharmaceuticals Inc Polymorphes de sépiaptérine et leurs sels
JP7811085B2 (ja) * 2017-09-01 2026-02-04 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピアプテリンを含む医薬組成物及びその使用
EP3801534B1 (en) 2018-05-30 2026-02-18 PTC Therapeutics MP, Inc. Treatment of phenylketonuria with sepiapterin
FI3801536T3 (fi) 2018-05-30 2024-08-29 Ptc Therapeutics Mp Inc Sepiapteriinin antaminen ilman ruokaa käytettäväksi menetelmässä sepiapteriinin plasma-altistuksen lisäämiseksi
AU2019277372B2 (en) * 2018-05-30 2024-12-19 Ptc Therapeutics Mp, Inc. Pharmaceutically acceptable salts of sepiapterin
IL290321B1 (en) 2019-08-05 2026-04-01 Ptc Therapeutics Inc Use of spiapterin and its metabolites for radiation exposure treatment
IL291565B1 (en) * 2019-09-25 2026-04-01 Ptc Therapeutics Inc Method for treating phenylalanine irregularity

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