JP2021525746A5 - - Google Patents
Info
- Publication number
- JP2021525746A5 JP2021525746A5 JP2020566737A JP2020566737A JP2021525746A5 JP 2021525746 A5 JP2021525746 A5 JP 2021525746A5 JP 2020566737 A JP2020566737 A JP 2020566737A JP 2020566737 A JP2020566737 A JP 2020566737A JP 2021525746 A5 JP2021525746 A5 JP 2021525746A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- subject
- food
- sepiapterin
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024146283A JP7855033B2 (ja) | 2018-05-30 | 2024-08-28 | テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862677926P | 2018-05-30 | 2018-05-30 | |
| US62/677,926 | 2018-05-30 | ||
| US201862771397P | 2018-11-26 | 2018-11-26 | |
| US62/771,397 | 2018-11-26 | ||
| US201962822365P | 2019-03-22 | 2019-03-22 | |
| US62/822,365 | 2019-03-22 | ||
| GC2019-37662 | 2019-05-28 | ||
| GC201937662 | 2019-05-28 | ||
| PCT/US2019/034515 WO2019232126A1 (en) | 2018-05-30 | 2019-05-30 | Compositions and methods for increasing tetrahydrobiopterin plasma exposure |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024146283A Division JP7855033B2 (ja) | 2018-05-30 | 2024-08-28 | テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525746A JP2021525746A (ja) | 2021-09-27 |
| JP2021525746A5 true JP2021525746A5 (enExample) | 2022-06-03 |
| JP7547215B2 JP7547215B2 (ja) | 2024-09-09 |
Family
ID=68699016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566737A Active JP7547215B2 (ja) | 2018-05-30 | 2019-05-30 | テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12257252B2 (enExample) |
| EP (1) | EP3801534B1 (enExample) |
| JP (1) | JP7547215B2 (enExample) |
| CN (1) | CN112654356A (enExample) |
| BR (1) | BR112020024329A2 (enExample) |
| CA (1) | CA3102105A1 (enExample) |
| DK (1) | DK3801534T3 (enExample) |
| FI (1) | FI3801534T3 (enExample) |
| MX (1) | MX2020012980A (enExample) |
| WO (1) | WO2019232126A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA46973A (fr) | 2016-11-29 | 2019-10-09 | Censa Pharmaceuticals Inc | Polymorphes de sépiaptérine et leurs sels |
| MA46972A (fr) | 2016-11-29 | 2019-10-09 | Censa Pharmaceuticals Inc | Forme polymorphe de sépiaptérine |
| JP7811085B2 (ja) | 2017-09-01 | 2026-02-04 | ピーティーシー セラピューティクス エムピー,インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
| FI3801536T3 (fi) * | 2018-05-30 | 2024-08-29 | Ptc Therapeutics Mp Inc | Sepiapteriinin antaminen ilman ruokaa käytettäväksi menetelmässä sepiapteriinin plasma-altistuksen lisäämiseksi |
| EP3801534B1 (en) | 2018-05-30 | 2026-02-18 | PTC Therapeutics MP, Inc. | Treatment of phenylketonuria with sepiapterin |
| EP4093405A1 (en) * | 2020-01-24 | 2022-11-30 | PTC Therapeutics MP, Inc. | Methods for treating parkinson's disease with sepiapterin |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5925323A (ja) | 1982-03-03 | 1984-02-09 | 鐘淵化学工業株式会社 | プテリン誘導体からなる脳内神経伝達物質の関わる疾病の治療剤 |
| US5910304A (en) | 1982-12-13 | 1999-06-08 | Texas A&M University System | Low-dose oral administration of interferons |
| CA1320905C (en) | 1986-11-06 | 1993-08-03 | Joseph M. Cummins | Treatment of immuno-resistant disease |
| JP2002515965A (ja) | 1995-08-18 | 2002-05-28 | ダブリュー. ランドリ,ドナルド | 抗体触媒反応の調節による有機化合物の検出 |
| US6036949A (en) | 1998-03-05 | 2000-03-14 | Amarillo Biosciences, Inc. | Treatment of fibromyalgia with low doses of interferon |
| US8188043B2 (en) | 1999-07-28 | 2012-05-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine in therapeutic angiogenesis and vasculogenesis |
| FR2859996B1 (fr) | 2003-09-19 | 2006-02-03 | Aventis Pharma Sa | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
| WO2005048926A2 (en) | 2003-11-13 | 2005-06-02 | The General Hospital Corporation | Methods for treating pain |
| PL1708690T3 (pl) | 2003-11-17 | 2017-01-31 | Biomarin Pharmaceutical Inc. | Leczenie fenyloketonurii za pomocą BH4 |
| JP5184783B2 (ja) | 2003-11-17 | 2013-04-17 | バイオマリン ファーマシューティカル インコーポレイテッド | テトラヒドロビオプテリン、及びテトラヒドロビオプテリン類似体の製造方法 |
| EP1687308B1 (en) | 2003-11-17 | 2019-06-12 | Merck & Cie | Process for preparating (6R)-L-erythrotetrahydrobiopterin hydrochloride crystalline form B from other crystalline forms |
| KR20070084270A (ko) | 2004-11-17 | 2007-08-24 | 바이오마린 파머수티컬 인크. | 안정한 정제 제형물 |
| JP2008523090A (ja) | 2004-12-08 | 2008-07-03 | バイオマリン ファーマシューティカル インコーポレイテッド | 新生児肺高血圧症の治療のための方法および組成物 |
| BRPI0609421B1 (pt) | 2005-04-28 | 2021-06-01 | Shiratori Pharmaceutical Co., Ltd. | Processos para produção de um composto 1,1-bis-alquil sulfonila, para produção de um composto aldeído, e para produção de um derivado de hidrazona |
| US20080075666A1 (en) | 2006-08-25 | 2008-03-27 | Dudley Samuel C Jr | Methods and compositions for treating diastolic dysfunction |
| LT2545939T (lt) | 2007-04-11 | 2021-03-10 | Biomarin Pharmaceutical Inc. | Tetrahidrobiopterinas, skirtas gydyti ligas, susijusias supadidėjusiu fenilalanino kiekiu |
| WO2010017570A2 (de) | 2008-08-12 | 2010-02-18 | Orpha Swiss Gmbh | Pharmazeutische darreichungsform enthaltend tetrahydrobiopterin |
| EP2562176B1 (en) | 2010-04-22 | 2018-08-15 | Nihon University | Medicinal agent and beverage/food for preventing cerebral dysfunction and improving same |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| CN103458900A (zh) * | 2011-03-01 | 2013-12-18 | 鲁必康研究私人有限公司 | 四氢生物蝶呤的稳定组合物 |
| US9216178B2 (en) * | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
| CN104736539B (zh) | 2012-05-07 | 2017-09-01 | 白鸟制药株式会社 | 墨蝶呤和四氢乳酰蝶呤的制造法 |
| EP3213062B1 (en) | 2014-10-31 | 2020-02-12 | Children's Medical Center Corporation | Methods and assays relating to sepiapterin reductase inhibition |
| MA46972A (fr) | 2016-11-29 | 2019-10-09 | Censa Pharmaceuticals Inc | Forme polymorphe de sépiaptérine |
| MA46973A (fr) | 2016-11-29 | 2019-10-09 | Censa Pharmaceuticals Inc | Polymorphes de sépiaptérine et leurs sels |
| JP7811085B2 (ja) * | 2017-09-01 | 2026-02-04 | ピーティーシー セラピューティクス エムピー,インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
| EP3801534B1 (en) | 2018-05-30 | 2026-02-18 | PTC Therapeutics MP, Inc. | Treatment of phenylketonuria with sepiapterin |
| FI3801536T3 (fi) | 2018-05-30 | 2024-08-29 | Ptc Therapeutics Mp Inc | Sepiapteriinin antaminen ilman ruokaa käytettäväksi menetelmässä sepiapteriinin plasma-altistuksen lisäämiseksi |
| AU2019277372B2 (en) * | 2018-05-30 | 2024-12-19 | Ptc Therapeutics Mp, Inc. | Pharmaceutically acceptable salts of sepiapterin |
| IL290321B1 (en) | 2019-08-05 | 2026-04-01 | Ptc Therapeutics Inc | Use of spiapterin and its metabolites for radiation exposure treatment |
| IL291565B1 (en) * | 2019-09-25 | 2026-04-01 | Ptc Therapeutics Inc | Method for treating phenylalanine irregularity |
-
2019
- 2019-05-30 EP EP19810058.8A patent/EP3801534B1/en active Active
- 2019-05-30 WO PCT/US2019/034515 patent/WO2019232126A1/en not_active Ceased
- 2019-05-30 CA CA3102105A patent/CA3102105A1/en active Pending
- 2019-05-30 FI FIEP19810058.8T patent/FI3801534T3/fi active
- 2019-05-30 DK DK19810058.8T patent/DK3801534T3/da active
- 2019-05-30 BR BR112020024329-9A patent/BR112020024329A2/pt unknown
- 2019-05-30 US US17/059,632 patent/US12257252B2/en active Active
- 2019-05-30 JP JP2020566737A patent/JP7547215B2/ja active Active
- 2019-05-30 CN CN201980050730.3A patent/CN112654356A/zh active Pending
- 2019-05-30 MX MX2020012980A patent/MX2020012980A/es unknown
-
2025
- 2025-03-04 US US19/070,026 patent/US20250195529A1/en active Pending
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