JP2021524744A - 分子遺伝子シグネチャーとその使用方法 - Google Patents

分子遺伝子シグネチャーとその使用方法 Download PDF

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JP2021524744A
JP2021524744A JP2020564841A JP2020564841A JP2021524744A JP 2021524744 A JP2021524744 A JP 2021524744A JP 2020564841 A JP2020564841 A JP 2020564841A JP 2020564841 A JP2020564841 A JP 2020564841A JP 2021524744 A JP2021524744 A JP 2021524744A
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hla
cancer
expression level
biological sample
patient
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JP2021524744A5 (https=
JPWO2019226514A5 (https=
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ウォーレン サラ
ウォーレン サラ
ダナハー パトリック
ダナハー パトリック
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ナノストリング テクノロジーズ，インコーポレイティド
ナノストリング テクノロジーズ，インコーポレイティド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2020564841A 2018-05-21 2019-05-20 分子遺伝子シグネチャーとその使用方法 Pending JP2021524744A (ja)

Priority Applications (1)

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JP2024034926A JP2024053048A (ja) 2018-05-21 2024-03-07 分子遺伝子シグネチャーとその使用方法

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US201862674285P 2018-05-21 2018-05-21
US62/674,285 2018-05-21
US201862747853P 2018-10-19 2018-10-19
US62/747,853 2018-10-19
PCT/US2019/033052 WO2019226514A2 (en) 2018-05-21 2019-05-20 Molecular gene signatures and methods of using same

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JP2021524744A true JP2021524744A (ja) 2021-09-16
JP2021524744A5 JP2021524744A5 (https=) 2022-05-30
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JP2024034926A Pending JP2024053048A (ja) 2018-05-21 2024-03-07 分子遺伝子シグネチャーとその使用方法

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US (1) US20210363590A1 (https=)
EP (1) EP3797173A2 (https=)
JP (2) JP2021524744A (https=)
CN (1) CN112771177A (https=)
AU (1) AU2019275404A1 (https=)
CA (1) CA3100200A1 (https=)
WO (1) WO2019226514A2 (https=)

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US20230062248A1 (en) * 2020-01-31 2023-03-02 Allarity Therapeutics Europe ApS Methods for predicting ixabepilone responsiveness in cancer patients
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US20230257825A1 (en) * 2022-02-04 2023-08-17 City Of Hope Breast cancer biomarkers and methods of use
US20260002216A1 (en) * 2022-02-18 2026-01-01 London Health Sciences Centre Research Inc. Immune Classification Tool for Determining Survival Outcomes in Cancer
CN115896290B (zh) * 2022-11-29 2023-11-24 中国人民解放军海军军医大学 Trim21基因检测在肿瘤诊断、治疗选择和预后评估中的应用
WO2024227553A1 (en) * 2023-05-01 2024-11-07 The Chancellor, Masters And Scholars Of The University Of Oxford Biomarkers for use in cancer treatment and predicting responsiveness to a cancer therapy
WO2024234348A1 (en) * 2023-05-17 2024-11-21 Yanjun Wang Biomarker for immune checkpoint blockade therapy in nsclc
CN119685476A (zh) * 2024-05-29 2025-03-25 深圳湾实验室 一种与癌症预后相关的基因标志物及其应用
CN120775978A (zh) * 2025-03-14 2025-10-14 浙江省肿瘤医院 乳头状甲状腺癌早期预测标志物的筛选方法及应用

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US20210363590A1 (en) 2021-11-25
EP3797173A2 (en) 2021-03-31
WO2019226514A2 (en) 2019-11-28
CN112771177A (zh) 2021-05-07
WO2019226514A3 (en) 2019-12-26
AU2019275404A1 (en) 2020-12-03
CA3100200A1 (en) 2019-11-28
JP2024053048A (ja) 2024-04-12

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