|
US5112739A
(en)
|
1988-08-02 |
1992-05-12 |
Polaroid Corporation |
Enzyme controlled release system
|
|
DE19512484A1
(de)
|
1995-04-04 |
1996-10-17 |
Bayer Ag |
Kohlenhydratmodifizierte Cytostatika
|
|
EP0795334B1
(de)
|
1996-03-12 |
2006-02-01 |
Sanofi-Aventis Deutschland GmbH |
Neuartige Prodrugs für die Therapie von Tumoren und entzündlichen Erkrankungen
|
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
WO1998019705A1
(en)
|
1996-11-05 |
1998-05-14 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
WO2004050089A1
(en)
|
2002-12-05 |
2004-06-17 |
Schering Ag |
Epothilone analogs for site specific delivery in the treatment of proliferative diseases
|
|
EP3434275A1
(en)
|
2003-11-06 |
2019-01-30 |
Seattle Genetics, Inc. |
Assay for cancer cells based on the use of auristatin conjugates with antibodies
|
|
US20060088522A1
(en)
|
2004-09-10 |
2006-04-27 |
Wyeth |
Humanized anti-5T4 antibodies and anti-5T4/calicheamicin conjugates
|
|
SI1912671T1
(en)
|
2005-07-18 |
2018-01-31 |
Seattle Genetics, Inc. |
Conjugates beta-glucuronide linker-drug
|
|
CN101287500A
(zh)
|
2005-08-19 |
2008-10-15 |
恩多塞特公司 |
多药物配体缀合物
|
|
KR20090039739A
(ko)
*
|
2006-08-03 |
2009-04-22 |
아스트라제네카 아베 |
αＶβ６에 대해 작용하는 항체 및 그의 용도
|
|
KR20090057235A
(ko)
|
2006-09-15 |
2009-06-04 |
엔존 파마슈티컬즈, 인코포레이티드 |
리신계 폴리머 링커
|
|
UA94628C2
(ru)
|
2006-10-27 |
2011-05-25 |
Дженентек, Инк. |
Гуманизированное моноклональное антитело, которое связывается с steap-1, и его применение
|
|
KR101512203B1
(ko)
|
2006-11-10 |
2015-04-15 |
가부시키가이샤 리부텍쿠 |
ｉｎ ｖｉｖｏ 에서 항종양 활성을 갖는 항인간 Ｄｌｋ－１ 항체
|
|
CL2007003622A1
(es)
*
|
2006-12-13 |
2009-08-07 |
Medarex Inc |
Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales.
|
|
WO2009016647A1
(en)
|
2007-08-01 |
2009-02-05 |
Council Of Scientific & Industrial Research |
Pyrrolo [2,1-c][1, 4] benzodiazepine-glycoside prodrugs useful as a selective anti tumor agent
|
|
AU2008312457B2
(en)
|
2007-10-19 |
2014-04-17 |
Genentech, Inc. |
Cysteine engineered anti-TENB2 antibodies and antibody drug conjugates
|
|
WO2009116670A1
(ja)
|
2008-03-17 |
2009-09-24 |
株式会社リブテック |
in vivoで抗腫瘍活性を有する抗ヒトDlk-1抗体
|
|
AU2010238723A1
(en)
|
2009-04-23 |
2011-11-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-human ROR1 antibodies
|
|
WO2011066418A1
(en)
|
2009-11-25 |
2011-06-03 |
Academia Sinica |
The tumor-selective anti-cancer prodrug bqc-g
|
|
FR2960153B1
(fr)
|
2010-05-20 |
2012-08-17 |
Centre Nat Rech Scient |
Nouveaux bras autoreactifs et prodrogues les comprenant
|
|
US9591882B2
(en)
|
2010-08-05 |
2017-03-14 |
Robert LaGrand Duffin |
Absorbent sleeve
|
|
EP3219731A1
(en)
|
2010-10-01 |
2017-09-20 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
|
KR20120107741A
(ko)
|
2011-03-22 |
2012-10-04 |
한국생명공학연구원 |
패혈증 단백질 치료제의 효능 분석 및 스크리닝 방법
|
|
KR101438265B1
(ko)
|
2011-04-04 |
2014-09-05 |
한국생명공학연구원 |
Ｄｌｋ１ 특이적 인간 항체 및 이를 포함하는 약학적 조성물
|
|
WO2012138102A2
(ko)
|
2011-04-04 |
2012-10-11 |
한국생명공학연구원 |
Ｄｌｋ１ 특이적 인간 항체 및 이를 포함하는 약학적 조성물
|
|
WO2012148427A1
(en)
|
2011-04-29 |
2012-11-01 |
Hewlett-Packard Development Company, L.P. |
Systems and methods for in-memory processing of events
|
|
US20120308584A1
(en)
|
2011-05-08 |
2012-12-06 |
Legochem Biosciences, Inc. |
Protein-active agent conjugates and method for preparing the same
|
|
US9526798B2
(en)
|
2011-10-14 |
2016-12-27 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
US9884123B2
(en)
|
2012-01-03 |
2018-02-06 |
Invictus Oncology Pvt. Ltd. |
Ligand-targeted molecules and methods thereof
|
|
EP4706769A2
(en)
*
|
2012-12-03 |
2026-03-11 |
NovImmune SA |
Anti-cd47 antibodies and methods of use thereof
|
|
BR112015014669B1
(pt)
|
2012-12-21 |
2023-09-26 |
Medimmune Limited |
Compostos pirrolobenzodiazepinas, conjugados compreendendo os mesmos e uso destes para tratar uma doença proliferativa
|
|
KR20220041957A
(ko)
|
2013-03-15 |
2022-04-01 |
아비에 도이치란트 게엠베하 운트 콤파니 카게 |
항-egfr 항체 약물 접합체 제형
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2015052533A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
AU2014337555C1
(en)
|
2013-10-15 |
2021-01-28 |
Seagen Inc. |
PEGylated drug-linkers for improved Ligand-Drug Conjugate pharmacokinetics
|
|
JP6609563B2
(ja)
|
2013-11-26 |
2019-11-20 |
ノバルティス アーゲー |
ケトンで修飾されたポリペプチドをオキシム複合化する方法
|
|
WO2015095755A1
(en)
|
2013-12-19 |
2015-06-25 |
Seattle Genetics, Inc. |
Methylene carbamate linkers for use with targeted-drug conjugates
|
|
EP2913064A1
(en)
|
2014-02-26 |
2015-09-02 |
celares GmbH |
Branched drug-linker conjugates for the coupling to biological targeting molecules
|
|
KR101628872B1
(ko)
*
|
2014-05-28 |
2016-06-09 |
주식회사 레고켐 바이오사이언스 |
자가-희생 기를 포함하는 화합물
|
|
WO2015197582A1
(en)
*
|
2014-06-27 |
2015-12-30 |
Innate Pharma |
Monomeric multispecific antigen binding proteins
|
|
TWI805109B
(zh)
*
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
HRP20241124T1
(hr)
|
2014-09-11 |
2024-11-22 |
Seagen Inc. |
Ciljana isporuka lijekovitih tvari koje sadrže tercijarni amin
|
|
US20160158377A1
(en)
|
2014-12-09 |
2016-06-09 |
Abbvie Inc. |
BCL-XL Inhibitory Compounds and Antibody Drug Conjugates Including the Same
|
|
KR20160080832A
(ko)
|
2014-12-29 |
2016-07-08 |
주식회사 레고켐 바이오사이언스 |
리피바디 유도체-약물 복합체, 그 제조방법 및 용도
|
|
CA2973978A1
(en)
|
2015-01-14 |
2016-07-21 |
The Brigham And Women's Hospital, Inc. |
Treatment of cancer with anti-lap monoclonal antibodies
|
|
AR103442A1
(es)
|
2015-01-16 |
2017-05-10 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígenos quiméricos específicos de ror1
|
|
PL3250237T3
(pl)
|
2015-01-30 |
2021-12-13 |
Sutro Biopharma, Inc. |
Pochodne hemiasterliny do koniugacji i terapii
|
|
WO2016142768A1
(en)
|
2015-03-10 |
2016-09-15 |
Eureka Therapeutics, Inc. |
Ror2 antibody
|
|
WO2017051254A1
(en)
|
2015-09-25 |
2017-03-30 |
Legochem Biosciences, Inc. |
Compositions and methods related to anti-egfr antibody drug conjugates
|
|
WO2017051249A1
(en)
*
|
2015-09-25 |
2017-03-30 |
Legochem Biosciences, Inc. |
Compositions and methods related to anti-cd19 antibody drug conjugates
|
|
MX2018004515A
(es)
|
2015-10-13 |
2019-04-15 |
Eureka Therapeutics Inc |
Agentes de anticuerpo especificos para cd19 humano y usos de los mismos.
|
|
US11167040B2
(en)
|
2015-11-25 |
2021-11-09 |
Legochem Biosciences, Inc. |
Conjugates comprising peptide groups and methods related thereto
|
|
CN107847605B
(zh)
*
|
2015-11-25 |
2021-12-24 |
乐高化学生物科学股份有限公司 |
包含分支接头的抗体-药物缀合物及其相关方法
|
|
LT3380124T
(lt)
|
2015-11-25 |
2024-06-25 |
Ligachem Biosciences Inc. |
Konjugatai, apimantys savaime skaidančias grupes, ir su jais susiję būdai
|
|
RU2651776C2
(ru)
|
2015-12-01 |
2018-04-23 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Биспецифические антитела против cd3*cd19
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
CA3040812A1
(en)
*
|
2016-11-04 |
2018-05-11 |
Novimmune Sa |
Anti-cd19 antibodies and methods of use thereof
|
|
JP2019535731A
(ja)
|
2016-11-21 |
2019-12-12 |
オービーアイ ファーマ，インコーポレイテッド |
コンジュゲートさせた生物学的分子、医薬組成物及び方法
|
|
CN110300601B
(zh)
|
2017-02-08 |
2024-01-05 |
Adc治疗有限公司 |
吡咯并苯并二氮杂䓬-抗体缀合物
|
|
KR101938800B1
(ko)
|
2017-03-29 |
2019-04-10 |
주식회사 레고켐 바이오사이언스 |
피롤로벤조디아제핀 이량체 전구체 및 이의 리간드-링커 접합체 화합물
|
|
WO2018182341A1
(ko)
|
2017-03-29 |
2018-10-04 |
주식회사 레고켐 바이오사이언스 |
피롤로벤조디아제핀 이량체 전구체 및 이의 리간드-링커 접합체 화합물
|
|
AR113224A1
(es)
|
2017-04-28 |
2020-02-19 |
Novartis Ag |
Conjugados de anticuerpo que comprenden un agonista de sting
|
|
CA3067829A1
(en)
|
2017-06-23 |
2018-12-27 |
VelosBio Inc. |
Ror1 antibody immunoconjugates
|
|
KR20190018400A
(ko)
|
2017-08-14 |
2019-02-22 |
주식회사 레고켐 바이오사이언스 |
EGFRvIII에 대한 항체를 포함하는 항체 약물 접합체
|
|
US11306141B2
(en)
|
2017-09-08 |
2022-04-19 |
Y-Biologics Inc. |
Antibody against human DLK1 and use thereof
|
|
IL278480B1
(en)
|
2018-05-09 |
2026-04-01 |
Ligachem Biosciences Inc |
Compositions and methods related to anti-CD19 antibody drug conjugates
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|
|
KR20200084802A
(ko)
|
2019-01-03 |
2020-07-13 |
주식회사 레고켐 바이오사이언스 |
안전성이 향상된 피롤로벤조디아제핀 이량체 화합물 및 이의 용도
|
|
MX2021010453A
(es)
|
2019-03-06 |
2021-09-21 |
Legochem Biosciences Inc |
Conjugados anticuerpo-farmaco que comprenden anticuerpos contra dlk1 humana y uso de estos.
|
|
CN110784759B
(zh)
|
2019-08-12 |
2022-08-12 |
腾讯科技（深圳）有限公司 |
弹幕信息处理方法、装置、电子设备及存储介质
|
|
KR20210028544A
(ko)
|
2019-09-04 |
2021-03-12 |
주식회사 레고켐 바이오사이언스 |
인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도
|