JP2021523206A5 - - Google Patents

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Publication number
JP2021523206A5
JP2021523206A5 JP2020564219A JP2020564219A JP2021523206A5 JP 2021523206 A5 JP2021523206 A5 JP 2021523206A5 JP 2020564219 A JP2020564219 A JP 2020564219A JP 2020564219 A JP2020564219 A JP 2020564219A JP 2021523206 A5 JP2021523206 A5 JP 2021523206A5
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JP
Japan
Prior art keywords
alkyl
membered monocyclic
occurrence
independently
alkynyl
Prior art date
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Application number
JP2020564219A
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English (en)
Japanese (ja)
Other versions
JP7359782B2 (ja
JP2021523206A (ja
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Priority claimed from PCT/US2019/032018 external-priority patent/WO2019222101A1/en
Publication of JP2021523206A publication Critical patent/JP2021523206A/ja
Publication of JP2021523206A5 publication Critical patent/JP2021523206A5/ja
Application granted granted Critical
Publication of JP7359782B2 publication Critical patent/JP7359782B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020564219A 2018-05-14 2019-05-13 ブルトン型チロシンキナーゼに対する阻害剤 Active JP7359782B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862671053P 2018-05-14 2018-05-14
US62/671,053 2018-05-14
PCT/US2019/032018 WO2019222101A1 (en) 2018-05-14 2019-05-13 Inhibiting agents for bruton's tyrosine kinase

Publications (3)

Publication Number Publication Date
JP2021523206A JP2021523206A (ja) 2021-09-02
JP2021523206A5 true JP2021523206A5 (enExample) 2022-05-18
JP7359782B2 JP7359782B2 (ja) 2023-10-11

Family

ID=67002348

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020564219A Active JP7359782B2 (ja) 2018-05-14 2019-05-13 ブルトン型チロシンキナーゼに対する阻害剤

Country Status (9)

Country Link
US (1) US10899753B2 (enExample)
EP (1) EP3793994B1 (enExample)
JP (1) JP7359782B2 (enExample)
AR (1) AR115085A1 (enExample)
ES (1) ES2968222T3 (enExample)
MA (1) MA52629A (enExample)
TW (1) TW202016097A (enExample)
UY (1) UY38233A (enExample)
WO (1) WO2019222101A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11820760B2 (en) * 2018-10-15 2023-11-21 Biogen Ma Inc. Crystalline polymorphs of Bruton's tyrosine kinase inhibitors
CN110627775B (zh) * 2019-10-24 2026-01-30 特科罗生物科技(成都)有限公司 一种小分子化合物
EP4081514A1 (en) * 2019-12-23 2022-11-02 Biogen MA Inc. Btk inhibitors
CN112062691B (zh) * 2020-06-18 2022-12-09 中国农业科学院油料作物研究所 一种柠檬醛苯丁酸肟酯类化合物及其合成方法和应用
EP4313023A1 (en) 2021-04-02 2024-02-07 Biogen MA Inc. Combination treatment methods of multiple sclerosis
KR20240128831A (ko) 2021-12-30 2024-08-27 베이진 스위찰랜드 게엠베하 브루톤 티로신 키나아제(btk) 억제제와 e3 리가아제 리간드의 접합에 의한 btk의 분해 및 사용 방법
JP7805983B2 (ja) 2022-03-22 2026-01-26 アッヴィ・インコーポレイテッド ブルトン型チロシンキナーゼを分解するためのピリミジン

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
KR20140131955A (ko) 2012-03-09 2014-11-14 카나 바이오사이언스 인코포레이션 신규 트리아진 유도체
EP3444251B1 (en) 2013-12-11 2023-06-07 Biogen MA Inc. Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology
AU2014362231B2 (en) 2013-12-11 2019-04-04 Biogen Ma Inc. Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology
US20180282310A1 (en) 2015-06-10 2018-10-04 Biogen Ma Inc. Forms and compositions of biaryl inhibitors of bruton's tyrosine kinase

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