JP2021522246A - 癌治療のための併用 - Google Patents
癌治療のための併用 Download PDFInfo
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- JP2021522246A JP2021522246A JP2020559437A JP2020559437A JP2021522246A JP 2021522246 A JP2021522246 A JP 2021522246A JP 2020559437 A JP2020559437 A JP 2020559437A JP 2020559437 A JP2020559437 A JP 2020559437A JP 2021522246 A JP2021522246 A JP 2021522246A
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- pharmaceutically acceptable
- acceptable salt
- compound
- azd5991
- acalabrutinib
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| DK4054582T3 (da) | 2019-11-04 | 2025-12-01 | Astrazeneca Ab | Terapeutiske kombinationer af acalabrutinib og capivasertib til behandling af b-celle-maligniteter |
| AU2020409006A1 (en) * | 2019-12-18 | 2022-06-30 | Zeno Management, Inc. | Macrocyclic compounds |
| JP7900421B2 (ja) | 2021-06-11 | 2026-08-04 | ギリアード サイエンシーズ， インコーポレイテッド | Ｍｃｌ－１阻害剤と抗がん剤との組み合わせ |
| TWI861509B (zh) | 2021-06-11 | 2024-11-11 | 美商基利科學股份有限公司 | Mcl-1抑制劑與抗體藥物接合物之組合 |
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| CN103889987B (zh) | 2011-07-19 | 2016-09-14 | 默沙东有限责任公司 | 作为btk抑制剂的选择的咪唑并吡嗪类 |
| MX2017001656A (es) * | 2014-08-08 | 2017-07-24 | Pharmacyclics Llc | Combinaciones de inhibidor de tirosina cinasa de bruton y usos de estas. |
| CR20180499A (es) * | 2016-04-22 | 2019-01-25 | Astrazeneca Ab | Inhibidores de mcl1 macrocicliclos para tratar el cancer |
| CN107056786B (zh) * | 2016-10-14 | 2019-05-07 | 苏州明锐医药科技有限公司 | 阿卡替尼的制备方法 |
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| EA202092540A1 (ru) | 2021-03-17 |
| SG11202010528XA (en) | 2020-11-27 |
| AU2019263026A1 (en) | 2020-12-17 |
| WO2019211721A1 (en) | 2019-11-07 |
| MX2020011453A (es) | 2020-12-07 |
| MA52499A (fr) | 2021-04-14 |
| BR112020022020A2 (pt) | 2021-02-02 |
| EP3787620A1 (en) | 2021-03-10 |
| TW202014184A (zh) | 2020-04-16 |
| CA3097486A1 (en) | 2019-11-07 |
| US20210030718A1 (en) | 2021-02-04 |
| KR20210005182A (ko) | 2021-01-13 |
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