JP2021522208A5 - - Google Patents

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Publication number
JP2021522208A5
JP2021522208A5 JP2020558036A JP2020558036A JP2021522208A5 JP 2021522208 A5 JP2021522208 A5 JP 2021522208A5 JP 2020558036 A JP2020558036 A JP 2020558036A JP 2020558036 A JP2020558036 A JP 2020558036A JP 2021522208 A5 JP2021522208 A5 JP 2021522208A5
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JP
Japan
Prior art keywords
cells
exogenous
receptor
cd8αβ
optionally
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JP2020558036A
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English (en)
Japanese (ja)
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JP7529265B2 (ja
JP2021522208A (ja
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Priority claimed from PCT/US2019/028202 external-priority patent/WO2019204662A1/en
Publication of JP2021522208A publication Critical patent/JP2021522208A/ja
Publication of JP2021522208A5 publication Critical patent/JP2021522208A5/ja
Application granted granted Critical
Publication of JP7529265B2 publication Critical patent/JP7529265B2/ja
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JP2020558036A 2018-04-19 2019-04-18 CD8abおよびクラス1制限T細胞受容体の強制発現による細胞傷害性CD8細胞へのCD4 T細胞の再プログラミング Active JP7529265B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862659971P 2018-04-19 2018-04-19
US62/659,971 2018-04-19
PCT/US2019/028202 WO2019204662A1 (en) 2018-04-19 2019-04-18 Reprogramming cd4 t cells into cytotoxic cd8 cells by forced expression of cd8ab and class 1 restricted t cell receptors

Publications (3)

Publication Number Publication Date
JP2021522208A JP2021522208A (ja) 2021-08-30
JP2021522208A5 true JP2021522208A5 (enExample) 2022-04-25
JP7529265B2 JP7529265B2 (ja) 2024-08-06

Family

ID=68239931

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020558036A Active JP7529265B2 (ja) 2018-04-19 2019-04-18 CD8abおよびクラス1制限T細胞受容体の強制発現による細胞傷害性CD8細胞へのCD4 T細胞の再プログラミング

Country Status (12)

Country Link
US (2) US12377147B2 (enExample)
EP (1) EP3781177A4 (enExample)
JP (1) JP7529265B2 (enExample)
KR (1) KR20210003826A (enExample)
CN (1) CN112188895A (enExample)
AU (1) AU2019256536C1 (enExample)
CA (1) CA3097396A1 (enExample)
IL (1) IL278044B2 (enExample)
MA (1) MA52536A (enExample)
MX (1) MX2020011023A (enExample)
SG (1) SG11202010262TA (enExample)
WO (1) WO2019204662A1 (enExample)

Families Citing this family (8)

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CA3097396A1 (en) 2018-04-19 2019-10-24 Baylor College Of Medicine Reprogramming cd4 t cells into cytotoxic cd8 cells by forced expression of cd8ab and class 1 restricted t cell receptors
WO2020049496A1 (en) * 2018-09-05 2020-03-12 Glaxosmithkline Intellectual Property Development Limited T cell modification
GB201819540D0 (en) 2018-11-30 2019-01-16 Adaptimmune Ltd T cell modification
WO2020243134A1 (en) 2019-05-27 2020-12-03 Immatics US, Inc. Viral vectors and their use in adoptive cellular therapy
TW202241938A (zh) * 2020-12-31 2022-11-01 美商英麥提克斯股份有限公司 Cd8多肽、組合物及其使用方法
US12234473B2 (en) 2020-12-31 2025-02-25 Immatics US, Inc. CD8 polypeptides, compositions, and methods of using thereof
WO2022233956A1 (en) 2021-05-05 2022-11-10 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame
EP4501954A1 (en) 2023-08-02 2025-02-05 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft A nucleic acid encoding a cd8 alpha beta co-receptor, cells and pharmaceutical compositions comprising the same

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CA3097396A1 (en) 2018-04-19 2019-10-24 Baylor College Of Medicine Reprogramming cd4 t cells into cytotoxic cd8 cells by forced expression of cd8ab and class 1 restricted t cell receptors
WO2020049496A1 (en) 2018-09-05 2020-03-12 Glaxosmithkline Intellectual Property Development Limited T cell modification
GB201819540D0 (en) 2018-11-30 2019-01-16 Adaptimmune Ltd T cell modification

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