JP2016513458A5 - - Google Patents

Download PDF

Info

Publication number
JP2016513458A5
JP2016513458A5 JP2016501065A JP2016501065A JP2016513458A5 JP 2016513458 A5 JP2016513458 A5 JP 2016513458A5 JP 2016501065 A JP2016501065 A JP 2016501065A JP 2016501065 A JP2016501065 A JP 2016501065A JP 2016513458 A5 JP2016513458 A5 JP 2016513458A5
Authority
JP
Japan
Prior art keywords
cell
cancer
tmz
tumor
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016501065A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016513458A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/022786 external-priority patent/WO2014164554A1/en
Publication of JP2016513458A publication Critical patent/JP2016513458A/ja
Publication of JP2016513458A5 publication Critical patent/JP2016513458A5/ja
Pending legal-status Critical Current

Links

JP2016501065A 2013-03-10 2014-03-10 化学療法耐性免疫細胞 Pending JP2016513458A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361775668P 2013-03-10 2013-03-10
US61/775,668 2013-03-10
PCT/US2014/022786 WO2014164554A1 (en) 2013-03-10 2014-03-10 Chemotherapy-resistant immune cells

Publications (2)

Publication Number Publication Date
JP2016513458A JP2016513458A (ja) 2016-05-16
JP2016513458A5 true JP2016513458A5 (enExample) 2017-04-06

Family

ID=50639912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016501065A Pending JP2016513458A (ja) 2013-03-10 2014-03-10 化学療法耐性免疫細胞

Country Status (5)

Country Link
US (1) US20160024175A1 (enExample)
EP (1) EP2968601A1 (enExample)
JP (1) JP2016513458A (enExample)
HK (1) HK1220614A1 (enExample)
WO (1) WO2014164554A1 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3246042T3 (da) 2009-11-02 2019-10-14 Univ Emory Lægemiddelresistent immunterapi til behandling af cancer
SG11201505858VA (en) 2013-01-28 2015-09-29 St Jude Childrens Res Hospital A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
EP2997134B1 (en) 2013-05-14 2020-06-24 Board of Regents, The University of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
CA2913052A1 (en) 2013-05-24 2014-11-27 Board Of Regents, The University Of Texas System Chimeric antigen receptor-targeting monoclonal antibodies
WO2015080981A1 (en) * 2013-11-27 2015-06-04 Baylor College Of Medicine Csgp4-specific chimeric antigen receptor for cancer
DK3105335T3 (da) 2014-02-14 2020-01-13 Univ Texas Kimære antigenreceptorer og fremgangsmåder til fremstilling heraf
EP3805371A1 (en) 2014-05-15 2021-04-14 National University of Singapore Modified natural killer cells and uses thereof
AU2015292744C1 (en) 2014-07-21 2021-01-21 Novartis Ag Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
JP6831777B2 (ja) 2014-07-21 2021-02-17 ノバルティス アーゲー Cd33キメラ抗原受容体を使用する癌の処置
CA2964783C (en) * 2014-11-05 2024-01-23 Board Of Regents, The University Of Texas System Chimeric antigen receptors (car) to selectively target protein complexes
EP3227317A4 (en) * 2014-12-02 2018-04-25 Roger Williams Hospital Methods and compositons for treating cancer
HK1246180A1 (zh) * 2014-12-31 2018-09-07 Celgene Corporation 使用自然杀伤细胞治疗血液病症、实体瘤或感染性疾病的方法
US20160208018A1 (en) 2015-01-16 2016-07-21 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for ror1
US11497767B2 (en) 2015-02-18 2022-11-15 Enlivex Therapeutics R&D Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11512289B2 (en) 2015-02-18 2022-11-29 Enlivex Therapeutics Rdo Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11000548B2 (en) 2015-02-18 2021-05-11 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11318163B2 (en) 2015-02-18 2022-05-03 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11596652B2 (en) 2015-02-18 2023-03-07 Enlivex Therapeutics R&D Ltd Early apoptotic cells for use in treating sepsis
US11304976B2 (en) 2015-02-18 2022-04-19 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
JP6803339B2 (ja) 2015-04-21 2020-12-23 エンリヴェックス セラピューティクス リミテッド 治療用のプールされた血液アポトーシス細胞調製物及びそれらの使用
US12005078B2 (en) * 2015-09-03 2024-06-11 The Uab Research Foundation Genetically engineered drug resistant T cells and methods of using the same
JP7029401B2 (ja) 2016-02-02 2022-03-03 フレッド ハッチンソン キャンサー リサーチ センター 抗ror1抗体およびその使用
JP6884155B2 (ja) 2016-02-18 2021-06-09 エンリヴェックス セラピューティクス リミテッド 癌治療のための併用免疫療法及びサイトカイン制御療法
EP3500262A4 (en) * 2016-08-18 2020-03-25 The UAB Research Foundation COMPOSITIONS AND METHODS FOR CANCER IMMUNOTHERAPY
CA3044393A1 (en) * 2016-12-09 2018-06-14 The Uab Research Foundation Chimeric chlorotoxin receptors
CN110376718A (zh) * 2016-12-30 2019-10-25 玉晶光电(厦门)有限公司 光学成像镜头
CN117363636A (zh) 2017-03-27 2024-01-09 新加坡国立大学 一种编码嵌合受体的多核苷酸
MX2019011570A (es) 2017-03-27 2019-11-18 Nat Univ Singapore Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
US10561686B2 (en) * 2018-01-12 2020-02-18 Innovative Cellular Therapeutics CO., LTD. Modified cell expansion and uses thereof
JP7360174B2 (ja) 2018-02-09 2023-10-12 ナショナル ユニヴァーシティー オブ シンガポール ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用
US12441787B2 (en) 2018-04-02 2025-10-14 National University Of Singapore Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
US10869888B2 (en) 2018-04-17 2020-12-22 Innovative Cellular Therapeutics CO., LTD. Modified cell expansion and uses thereof
IL279367B2 (en) 2018-06-13 2026-05-01 Novartis Ag BCMA chimeric antigen receptors and their uses
WO2020044239A1 (en) 2018-08-29 2020-03-05 National University Of Singapore A method to specifically stimulate survival and expansion of genetically-modified immune cells
US12240915B2 (en) 2018-08-30 2025-03-04 Innovative Cellular Therapeutics Holdings, Ltd. Chimeric antigen receptor cells for treating solid tumor
US10918667B2 (en) 2018-11-20 2021-02-16 Innovative Cellular Therapeutics CO., LTD. Modified cell expressing therapeutic agent and uses thereof
CN113226340A (zh) 2018-11-26 2021-08-06 恩卡尔塔公司 同时扩增多种免疫细胞类型的方法、相关组合物及其在癌症免疫疗法中的用途
KR20210137085A (ko) 2019-03-05 2021-11-17 엔카르타, 인크. Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
US12702708B2 (en) 2019-08-21 2026-08-11 Innovative Cellular Therapeutics Holdings, Ltd. Presenting cell and use thereof in cell therapy
US12076343B2 (en) 2020-02-19 2024-09-03 Innovative Cellular Therapeutics Holdings, Ltd. Engineered safety in cell therapy
EP3915576A1 (en) * 2020-05-28 2021-12-01 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Chimeric antigen receptors specific for p95her2 and uses thereof
US12043654B2 (en) 2020-06-02 2024-07-23 Innovative Cellular Therapeutics Holdings, Ltd. Anti-GCC antibody and CAR thereof for treating digestive system cancer
MX2024003887A (es) 2021-10-14 2024-07-09 Arsenal Biosciences Inc Células inmunitarias que tienen arnch coespresados y sistemas de compuerta lógica.
JP2026504619A (ja) * 2022-11-07 2026-02-06 ネオイミューンテック, インコーポレイテッド 非メチル化mgmtプロモーターを含む腫瘍を治療する方法
TW202442689A (zh) 2023-03-03 2024-11-01 美商亞森諾生物科學公司 靶向psma及ca9之系統

Similar Documents

Publication Publication Date Title
Luo et al. Progress and prospect of immunotherapy for triple-negative breast cancer
Zhou et al. Mechanisms of tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance
JP6867347B2 (ja) 免疫療法のためのエンゲージャー細胞
Li et al. Increasing the safety and efficacy of chimeric antigen receptor T cell therapy
JP2016520302A5 (enExample)
JP2019517788A5 (enExample)
Huang et al. IGF1R-and ROR1-specific CAR T cells as a potential therapy for high risk sarcomas
Fiorenza et al. CAR-T Cell Therapy for Acute Myeloid Leukemia: Preclinical Rationale, Current Clinical Progress, and Barriers to Success: S. Fiorenza, CJ Turtle
Helmy et al. Cancer immunotherapy: accomplishments to date and future promise
Comoli et al. Development of adaptive immune effector therapies in solid tumors
JP2017503472A5 (enExample)
JP2022025110A (ja) 操作されたt細胞を用いて癌を処置するための方法
JP2015535689A5 (enExample)
IL276554B1 (en) Non-hla restricted t cell receptors and uses thereof
JP2021513347A5 (enExample)
Guo et al. Chimeric antigen receptor‐modified T cells for solid tumors: challenges and prospects
JP2019532997A5 (enExample)
JP2021521818A (ja) 有効な免疫療法のための抗原−サイトカイン複合体に用いた免疫エフェクター細胞及び分子アダプター
JP2022513053A5 (enExample)
JP2021512914A5 (enExample)
RU2015116901A (ru) Композиции и способы для имуннотерапии
JP2014512183A5 (enExample)
Azadi et al. Recent advances on immune targeted therapy of colorectal cancer using bi-specific antibodies and therapeutic vaccines
JP2018537536A5 (enExample)
JP2021522208A5 (enExample)