JP2016513458A - 化学療法耐性免疫細胞 - Google Patents

化学療法耐性免疫細胞 Download PDF

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JP2016513458A
JP2016513458A JP2016501065A JP2016501065A JP2016513458A JP 2016513458 A JP2016513458 A JP 2016513458A JP 2016501065 A JP2016501065 A JP 2016501065A JP 2016501065 A JP2016501065 A JP 2016501065A JP 2016513458 A JP2016513458 A JP 2016513458A
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cells
cell
cancer
tmz
tumor
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JP2016513458A5 (enExample
Inventor
チョウ、ケヴィン、クォン−ホン
イー、チョンチェン
シェーファー、ドナルド、アール．
ゴットシャルク、ステファン、エム．ジー．
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Baylor College of Medicine
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Baylor College of Medicine
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61K38/45—Transferases (2)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
    • A61K40/4205—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ ErbB4
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    • C12N9/10—Transferases (2.)
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    • C12N9/1007—Methyltransferases (general) (2.1.1.)
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/47—Brain; Nervous system
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    • C07K2319/00—Fusion polypeptide
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
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    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
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    • C12Y201/01063—Methylated-DNA-[protein]-cysteine S-methyltransferase (2.1.1.63), i.e. O6-methylguanine-DNA methyltransferase

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2016501065A 2013-03-10 2014-03-10 化学療法耐性免疫細胞 Pending JP2016513458A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361775668P 2013-03-10 2013-03-10
US61/775,668 2013-03-10
PCT/US2014/022786 WO2014164554A1 (en) 2013-03-10 2014-03-10 Chemotherapy-resistant immune cells

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JP2016513458A true JP2016513458A (ja) 2016-05-16
JP2016513458A5 JP2016513458A5 (enExample) 2017-04-06

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US (1) US20160024175A1 (enExample)
EP (1) EP2968601A1 (enExample)
JP (1) JP2016513458A (enExample)
HK (1) HK1220614A1 (enExample)
WO (1) WO2014164554A1 (enExample)

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JP2023529082A (ja) * 2020-05-28 2023-07-07 フンダシオ プリヴァーダ インスティトゥト ディンヴェスティガシオ オンコロジカ デ ヴァイ エブロン ｐ９５ＨＥＲ２に特異的なキメラ抗原受容体及びその使用

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
JP2020500903A (ja) * 2016-12-09 2020-01-16 ザ ユーエイビー リサーチ ファウンデーション キメラクロロトキシン受容体
JP2023078149A (ja) * 2016-12-09 2023-06-06 ザ ユーエイビー リサーチ ファウンデーション キメラクロロトキシン受容体
JP2023529082A (ja) * 2020-05-28 2023-07-07 フンダシオ プリヴァーダ インスティトゥト ディンヴェスティガシオ オンコロジカ デ ヴァイ エブロン ｐ９５ＨＥＲ２に特異的なキメラ抗原受容体及びその使用

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