JP2021522190A5 - - Google Patents
Info
- Publication number
- JP2021522190A5 JP2021522190A5 JP2020557325A JP2020557325A JP2021522190A5 JP 2021522190 A5 JP2021522190 A5 JP 2021522190A5 JP 2020557325 A JP2020557325 A JP 2020557325A JP 2020557325 A JP2020557325 A JP 2020557325A JP 2021522190 A5 JP2021522190 A5 JP 2021522190A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- cvb1
- modified
- pharmaceutical composition
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810338046.2 | 2018-04-16 | ||
| CN201810338046.2A CN110387353B (zh) | 2018-04-16 | 2018-04-16 | 一种用于治疗肿瘤的柯萨奇b组病毒 |
| PCT/CN2019/082608 WO2019201192A1 (zh) | 2018-04-16 | 2019-04-15 | 一种用于治疗肿瘤的柯萨奇b组病毒 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021522190A JP2021522190A (ja) | 2021-08-30 |
| JP2021522190A5 true JP2021522190A5 (enExample) | 2022-04-19 |
| JP7336791B2 JP7336791B2 (ja) | 2023-09-01 |
Family
ID=68240424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020557325A Active JP7336791B2 (ja) | 2018-04-16 | 2019-04-15 | 腫瘍を治療するためのコクサッキーウイルスｂ群 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210154249A1 (enExample) |
| EP (1) | EP3783100A4 (enExample) |
| JP (1) | JP7336791B2 (enExample) |
| KR (1) | KR102768669B1 (enExample) |
| CN (1) | CN110387353B (enExample) |
| AU (1) | AU2019254948B2 (enExample) |
| CA (1) | CA3097306A1 (enExample) |
| WO (1) | WO2019201192A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220267799A1 (en) * | 2019-08-05 | 2022-08-25 | Virogin Biotech Canada Ltd | Genetically modified enterovirus vectors |
| CN116751288A (zh) * | 2020-04-26 | 2023-09-15 | 北京万泰生物药业股份有限公司 | 针对柯萨奇病毒b1型的单克隆抗体及其用途 |
| CN118086228A (zh) * | 2022-11-28 | 2024-05-28 | 厦门大学 | 用于治疗肿瘤的柯萨奇b组1型病毒 |
| CN116769733B (zh) * | 2023-08-02 | 2023-11-03 | 中国医学科学院医学生物学研究所 | 一种柯萨奇病毒b组4型毒株及应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101065144B (zh) * | 2004-08-20 | 2012-06-13 | 溶瘤病毒有限公司 | 治疗血液癌症的方法和组合物 |
| US20100111873A1 (en) | 2007-02-20 | 2010-05-06 | Russell Stephen J | Treating cancer with viral nucleic acid |
| AU2012204467B2 (en) * | 2011-01-04 | 2016-08-18 | Sillajen, Inc. | Generation of antibodies to tumor antigens and generation of tumor specific complement dependent cytotoxicity by administration of oncolytic vaccinia virus |
| CN104936608A (zh) * | 2012-11-21 | 2015-09-23 | 杜克大学 | 用于人肿瘤的溶瘤脊髓灰质炎病毒 |
| JP6396891B2 (ja) * | 2013-04-17 | 2018-09-26 | 新日本製薬株式会社 | 遺伝子改変コクサッキーウイルス |
| CN103981152B (zh) * | 2014-04-16 | 2015-01-21 | 武汉博威德生物技术有限公司 | 一种柯萨奇病毒及其制备抗肿瘤药物之应用 |
| ES2833425T3 (es) * | 2014-07-16 | 2021-06-15 | Roussy Inst Gustave | Combinación de virus oncolítico con moduladores de punto de control inmunitario |
| JP7138946B2 (ja) * | 2016-09-27 | 2022-09-20 | セイター セラピューティクス エルエルシー | 最適化された腫瘍溶解性ウイルスおよびその使用 |
| CN109568350B (zh) * | 2017-09-29 | 2023-02-03 | 厦门大学 | 一种用于治疗肿瘤的柯萨奇病毒 |
-
2018
- 2018-04-16 CN CN201810338046.2A patent/CN110387353B/zh active Active
-
2019
- 2019-04-15 JP JP2020557325A patent/JP7336791B2/ja active Active
- 2019-04-15 WO PCT/CN2019/082608 patent/WO2019201192A1/zh not_active Ceased
- 2019-04-15 AU AU2019254948A patent/AU2019254948B2/en active Active
- 2019-04-15 US US17/047,783 patent/US20210154249A1/en active Pending
- 2019-04-15 KR KR1020207033014A patent/KR102768669B1/ko active Active
- 2019-04-15 EP EP19788373.9A patent/EP3783100A4/en active Pending
- 2019-04-15 CA CA3097306A patent/CA3097306A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6961788B2 (ja) | プログラム可能な腫瘍溶解性ウイルスワクチン系及びその適用 | |
| Jia et al. | Cancer gene therapy targeting cellular apoptosis machinery | |
| JP2021522190A5 (enExample) | ||
| JP6419706B2 (ja) | ミニプロモーターカセットを含むレトロウイルスベクター | |
| JP2008545406A5 (enExample) | ||
| JP2020528890A5 (enExample) | ||
| CN103981155B (zh) | 靶向肝癌溶瘤腺病毒的构建法和应用 | |
| US7364727B2 (en) | Metastatic colon cancer specific promoter and uses thereof | |
| WO2008031331A1 (fr) | Adénovirus recombinant orienté cible coexprimant p53 et p53aip1 humains | |
| CN110387353B (zh) | 一种用于治疗肿瘤的柯萨奇b组病毒 | |
| Shen et al. | Specific CEA-producing colorectal carcinoma cell killing with recombinant adenoviral vector containing cytosine deaminase gene | |
| CN104178460B (zh) | 一种受转录和转录后双调控的溶瘤腺病毒及其构建方法 | |
| Gao et al. | Gene therapy targeting hepatocellular carcinoma by a dual-regulated oncolytic adenovirus harboring the focal adhesion kinase shRNA | |
| JP2020537534A5 (enExample) | ||
| Shi et al. | Construction of a targeting adenoviral vector carrying AFP promoter for expressing EGFP gene in AFP producing hepatocarcinoma cell | |
| Durai et al. | Principles and applications of gene therapy in colon cancer | |
| JP2025049296A (ja) | 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 | |
| WO2016187908A1 (zh) | 重组溶瘤腺病毒及其应用 | |
| EP2345428B1 (en) | Preparation method of prostate tumor-targeted double-regulated oncolytic adenovirus expressing superantigen gene | |
| CN1242051A (zh) | 用于肿瘤治疗和预防的致细胞病变病毒 | |
| CN103981185B (zh) | 肝癌特异性gp73核心启动子及其筛选构建方法 | |
| US20210128653A1 (en) | Replication-enhanced oncolytic adenoviruses | |
| EP3822355A1 (en) | Anti-tumor composition | |
| RU2814581C1 (ru) | Генетический вектор Ad6/3-hTERT-GMCSF, содержащий геномные последовательности рекомбинантного аденовируса 6 серотипа, промотор теломеразы человека, ген гранулоцитарно-макрофагального колониестимулирующего фактора человека, а также ген белка файбер со встройкой домена fiber knob аденовируса 3 серотипа, обладающий повышенной трансдукцией в опухолевые клетки | |
| JP2022513347A5 (enExample) |