JP2021521274A5 - - Google Patents
Info
- Publication number
- JP2021521274A5 JP2021521274A5 JP2021504589A JP2021504589A JP2021521274A5 JP 2021521274 A5 JP2021521274 A5 JP 2021521274A5 JP 2021504589 A JP2021504589 A JP 2021504589A JP 2021504589 A JP2021504589 A JP 2021504589A JP 2021521274 A5 JP2021521274 A5 JP 2021521274A5
- Authority
- JP
- Japan
- Prior art keywords
- pdl
- cancer
- pharmaceutical composition
- composition according
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024005463A JP2024054138A (ja) | 2018-04-12 | 2024-01-17 | がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18382248 | 2018-04-12 | ||
| EP18382248.5 | 2018-04-12 | ||
| EP18382326.9 | 2018-05-14 | ||
| EP18382326 | 2018-05-14 | ||
| EP18382360.8 | 2018-05-25 | ||
| EP18382360 | 2018-05-25 | ||
| EP19382132 | 2019-02-22 | ||
| EP19382132.9 | 2019-02-22 | ||
| PCT/IB2019/000423 WO2019197903A1 (en) | 2018-04-12 | 2019-04-11 | Combination of lif inhibitors and pd-1 axis inhibitors for use in treating cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005463A Division JP2024054138A (ja) | 2018-04-12 | 2024-01-17 | がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021521274A JP2021521274A (ja) | 2021-08-26 |
| JP2021521274A5 true JP2021521274A5 (enExample) | 2022-04-18 |
| JP7423598B2 JP7423598B2 (ja) | 2024-01-29 |
Family
ID=67060425
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021504589A Active JP7423598B2 (ja) | 2018-04-12 | 2019-04-11 | がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ |
| JP2024005463A Ceased JP2024054138A (ja) | 2018-04-12 | 2024-01-17 | がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005463A Ceased JP2024054138A (ja) | 2018-04-12 | 2024-01-17 | がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210130453A1 (enExample) |
| EP (1) | EP3774895A1 (enExample) |
| JP (2) | JP7423598B2 (enExample) |
| KR (1) | KR20210021287A (enExample) |
| CN (1) | CN112585164A (enExample) |
| AU (1) | AU2019251289B2 (enExample) |
| CA (1) | CA3096779A1 (enExample) |
| IL (1) | IL277918A (enExample) |
| MA (1) | MA52231A (enExample) |
| SG (1) | SG11202009966SA (enExample) |
| WO (1) | WO2019197903A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3555132T1 (sl) * | 2016-12-19 | 2024-04-30 | Medimmune Limited | Protitelesa proti LIF in njihove uporabe |
| SG11202011170YA (en) * | 2018-05-14 | 2020-12-30 | Medimmune Ltd | Antibodies against lif and dosage forms thereof |
| CN114929741A (zh) * | 2019-12-04 | 2022-08-19 | 免疫医疗有限公司 | 针对lif的抗体及其用途 |
| WO2021183370A1 (en) | 2020-03-11 | 2021-09-16 | Purdue Research Foundation | Compounds with immunomodulatory activity and therapeutic uses thereof |
| WO2023159152A2 (en) * | 2022-02-17 | 2023-08-24 | Immune-Onc Therapeutics, Inc. | Combination therapy of lilrb antagonist and pd-1/pd-l1 axis inhibitor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| EP0307434B2 (en) | 1987-03-18 | 1998-07-29 | Scotgen Biopharmaceuticals, Inc. | Altered antibodies |
| ATE255131T1 (de) | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| AU4231393A (en) * | 1992-05-08 | 1993-12-13 | Genentech Inc. | Antibodies to leukemia inhibitory factor |
| JPH08511420A (ja) | 1993-06-16 | 1996-12-03 | セルテック・セラピューテイクス・リミテッド | 抗 体 |
| KR100940380B1 (ko) | 1999-01-15 | 2010-02-02 | 제넨테크, 인크. | 효과기 기능이 변화된 폴리펩티드 변이체 |
| US7361740B2 (en) | 2002-10-15 | 2008-04-22 | Pdl Biopharma, Inc. | Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis |
| EP2371860A1 (en) | 2010-04-05 | 2011-10-05 | Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron | Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation |
| JP2017527582A (ja) | 2014-09-10 | 2017-09-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Ｋ−Ｒａｓによって媒介されるシグナリング経路および悪性疾患の抗ｈＬＩＦ抗体によるターゲティング方法 |
| EP3173483A1 (en) * | 2015-11-27 | 2017-05-31 | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron | Agents for the treatment of diseases associated with undesired cell proliferation |
| SI3555132T1 (sl) | 2016-12-19 | 2024-04-30 | Medimmune Limited | Protitelesa proti LIF in njihove uporabe |
| US10583191B2 (en) * | 2016-12-19 | 2020-03-10 | Mosaic Biomedicals Slu | Antibodies against LIF and uses thereof |
-
2019
- 2019-04-11 WO PCT/IB2019/000423 patent/WO2019197903A1/en not_active Ceased
- 2019-04-11 AU AU2019251289A patent/AU2019251289B2/en not_active Ceased
- 2019-04-11 EP EP19733546.6A patent/EP3774895A1/en not_active Withdrawn
- 2019-04-11 CN CN201980038348.0A patent/CN112585164A/zh active Pending
- 2019-04-11 US US17/046,599 patent/US20210130453A1/en not_active Abandoned
- 2019-04-11 SG SG11202009966SA patent/SG11202009966SA/en unknown
- 2019-04-11 CA CA3096779A patent/CA3096779A1/en active Pending
- 2019-04-11 JP JP2021504589A patent/JP7423598B2/ja active Active
- 2019-04-11 KR KR1020207032587A patent/KR20210021287A/ko not_active Ceased
- 2019-04-11 MA MA052231A patent/MA52231A/fr unknown
-
2020
- 2020-10-11 IL IL277918A patent/IL277918A/en unknown
-
2024
- 2024-01-17 JP JP2024005463A patent/JP2024054138A/ja not_active Ceased
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