JP2023508202A5 - - Google Patents

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Publication number
JP2023508202A5
JP2023508202A5 JP2022539245A JP2022539245A JP2023508202A5 JP 2023508202 A5 JP2023508202 A5 JP 2023508202A5 JP 2022539245 A JP2022539245 A JP 2022539245A JP 2022539245 A JP2022539245 A JP 2022539245A JP 2023508202 A5 JP2023508202 A5 JP 2023508202A5
Authority
JP
Japan
Prior art keywords
antibody
amino acid
acid sequence
seq
antibody fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022539245A
Other languages
English (en)
Japanese (ja)
Other versions
JP7633259B2 (ja
JP2023508202A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/NL2020/050813 external-priority patent/WO2021133167A1/en
Publication of JP2023508202A publication Critical patent/JP2023508202A/ja
Priority to JP2023060823A priority Critical patent/JP2023076596A/ja
Publication of JP2023508202A5 publication Critical patent/JP2023508202A5/ja
Priority to JP2025018365A priority patent/JP2025083342A/ja
Application granted granted Critical
Publication of JP7633259B2 publication Critical patent/JP7633259B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022539245A 2019-12-24 2020-12-22 TGF-βRII結合タンパク質 Active JP7633259B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023060823A JP2023076596A (ja) 2019-12-24 2023-04-04 TGF-βRII結合タンパク質
JP2025018365A JP2025083342A (ja) 2019-12-24 2025-02-06 TGF-βRII結合タンパク質

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL2024576 2019-12-24
NL2024576 2019-12-24
PCT/NL2020/050813 WO2021133167A1 (en) 2019-12-24 2020-12-22 Tgf-beta-rii binding proteins

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2023060823A Division JP2023076596A (ja) 2019-12-24 2023-04-04 TGF-βRII結合タンパク質
JP2025018365A Division JP2025083342A (ja) 2019-12-24 2025-02-06 TGF-βRII結合タンパク質

Publications (3)

Publication Number Publication Date
JP2023508202A JP2023508202A (ja) 2023-03-01
JP2023508202A5 true JP2023508202A5 (enExample) 2023-04-25
JP7633259B2 JP7633259B2 (ja) 2025-02-19

Family

ID=69700252

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2022539245A Active JP7633259B2 (ja) 2019-12-24 2020-12-22 TGF-βRII結合タンパク質
JP2023060823A Pending JP2023076596A (ja) 2019-12-24 2023-04-04 TGF-βRII結合タンパク質
JP2025018365A Pending JP2025083342A (ja) 2019-12-24 2025-02-06 TGF-βRII結合タンパク質

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023060823A Pending JP2023076596A (ja) 2019-12-24 2023-04-04 TGF-βRII結合タンパク質
JP2025018365A Pending JP2025083342A (ja) 2019-12-24 2025-02-06 TGF-βRII結合タンパク質

Country Status (13)

Country Link
US (1) US12570747B2 (enExample)
EP (2) EP4269433A3 (enExample)
JP (3) JP7633259B2 (enExample)
KR (2) KR20230145542A (enExample)
CN (3) CN116199780A (enExample)
AR (2) AR120914A1 (enExample)
AU (2) AU2020412201B2 (enExample)
BR (1) BR112022012522A2 (enExample)
IL (2) IL294181A (enExample)
MX (2) MX2022007919A (enExample)
PH (1) PH12022551527A1 (enExample)
TW (2) TW202417513A (enExample)
WO (1) WO2021133167A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116199780A (zh) * 2019-12-24 2023-06-02 美勒斯公司 TGF-β-RII结合蛋白质
PE20241477A1 (es) * 2021-11-19 2024-07-17 Merus Nv Unidades de union multiespecificas que comprenden los dominios de union a pd-1 y tgf-brii
CN120731229A (zh) 2022-12-20 2025-09-30 美勒斯公司 FAP结合域以及结合FAP和TGF-βRII的双特异性结合部分

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001206899A (ja) * 1999-11-18 2001-07-31 Japan Tobacco Inc TGF−βII型受容体に対するヒトモノクローナル抗体及びその医薬用途
DK2314629T4 (da) 2002-07-18 2023-02-06 Merus Nv Rekombinant produktion af blandinger af antistoffer
EP2147594B1 (en) 2008-06-27 2013-11-13 Merus B.V. Antibody producing non-human mammals
JO3096B1 (ar) 2008-11-07 2017-03-15 Imclone Llc الأجسام المضادة لمستقبل ii مضاد tgfb
WO2012093125A1 (en) 2011-01-06 2012-07-12 Glaxo Group Limited Ligands that bind tgf-beta receptor ii
HUE042040T2 (hu) 2012-09-27 2019-06-28 Merus Nv Bispecifikus IGG antitestek mint T-sejt kapcsolók
WO2017015622A2 (en) * 2015-07-22 2017-01-26 Scholar Rock, Inc Gdf11 binding proteins and uses thereof
AR109770A1 (es) * 2016-10-18 2019-01-23 Lilly Co Eli ANTICUERPOS DEL RECEPTOR II DE TGF-b
MA52212A (fr) 2018-03-30 2021-02-17 Merus Nv Anticorps multivalent
CN116199780A (zh) * 2019-12-24 2023-06-02 美勒斯公司 TGF-β-RII结合蛋白质

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