JP2021523906A5 - - Google Patents

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Publication number
JP2021523906A5
JP2021523906A5 JP2020563980A JP2020563980A JP2021523906A5 JP 2021523906 A5 JP2021523906 A5 JP 2021523906A5 JP 2020563980 A JP2020563980 A JP 2020563980A JP 2020563980 A JP2020563980 A JP 2020563980A JP 2021523906 A5 JP2021523906 A5 JP 2021523906A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
pharmaceutical composition
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020563980A
Other languages
English (en)
Japanese (ja)
Other versions
JP7536654B2 (ja
JP2021523906A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/000541 external-priority patent/WO2019220204A2/en
Publication of JP2021523906A publication Critical patent/JP2021523906A/ja
Publication of JP2021523906A5 publication Critical patent/JP2021523906A5/ja
Priority to JP2024130558A priority Critical patent/JP2024160301A/ja
Application granted granted Critical
Publication of JP7536654B2 publication Critical patent/JP7536654B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020563980A 2018-05-14 2019-05-13 Lifに対する抗体及びそれらの投与形態 Active JP7536654B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024130558A JP2024160301A (ja) 2018-05-14 2024-08-07 Lifに対する抗体及びそれらの投与形態

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP18382327.7 2018-05-14
EP18382327 2018-05-14
EP18382359.0 2018-05-25
EP18382359 2018-05-25
EP19382208.7 2019-03-26
EP19382208 2019-03-26
EP19382331 2019-05-03
EP19382331.7 2019-05-03
PCT/IB2019/000541 WO2019220204A2 (en) 2018-05-14 2019-05-13 Antibodies against lif and dosage forms thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024130558A Division JP2024160301A (ja) 2018-05-14 2024-08-07 Lifに対する抗体及びそれらの投与形態

Publications (3)

Publication Number Publication Date
JP2021523906A JP2021523906A (ja) 2021-09-09
JP2021523906A5 true JP2021523906A5 (enExample) 2022-05-20
JP7536654B2 JP7536654B2 (ja) 2024-08-20

Family

ID=67902550

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020563980A Active JP7536654B2 (ja) 2018-05-14 2019-05-13 Lifに対する抗体及びそれらの投与形態
JP2024130558A Pending JP2024160301A (ja) 2018-05-14 2024-08-07 Lifに対する抗体及びそれらの投与形態

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024130558A Pending JP2024160301A (ja) 2018-05-14 2024-08-07 Lifに対する抗体及びそれらの投与形態

Country Status (10)

Country Link
US (1) US20220064279A1 (enExample)
EP (1) EP3794031A2 (enExample)
JP (2) JP7536654B2 (enExample)
KR (1) KR20210008514A (enExample)
CN (1) CN112638941A (enExample)
AU (1) AU2019269131B2 (enExample)
CA (1) CA3099406A1 (enExample)
MA (1) MA52021A (enExample)
SG (1) SG11202011170YA (enExample)
WO (1) WO2019220204A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019291307B2 (en) * 2018-06-18 2024-04-04 Fundacio Privada Institucio Catalana de Recerca i Estudis Avancats Combination of LIF inhibitors and platinum-based antineoplastic agents for use in treating cancer
CN120241997A (zh) 2019-02-18 2025-07-04 伊莱利利公司 治疗性抗体制剂
EP4069736A1 (en) * 2019-12-04 2022-10-12 MedImmune Limited Antibodies against lif and uses thereof
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
PL209392B1 (pl) 1999-01-15 2011-08-31 Genentech Inc Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
ES2363358B1 (es) 2009-04-03 2012-06-21 FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
EP2371860A1 (en) 2010-04-05 2011-10-05 Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation
WO2016040657A1 (en) * 2014-09-10 2016-03-17 The Regents Of The University Of California TARGETING K-RAS-MEDIATED SIGNALING PATHWAYS AND MALIGNANCY BY ANTI-hLIF ANTIBODIES
CA2963712A1 (en) 2014-10-21 2016-04-28 Ablynx Nv Treatment of il-6r related diseases
EP3173483A1 (en) * 2015-11-27 2017-05-31 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Agents for the treatment of diseases associated with undesired cell proliferation
US10583191B2 (en) * 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof
WO2019197903A1 (en) * 2018-04-12 2019-10-17 Mosaic Biomedicals Slu Combination of lif inhibitors and pd-1 axis inhibitors for use in treating cancer

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