JP2021520344A5 - - Google Patents

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Publication number
JP2021520344A5
JP2021520344A5 JP2020553619A JP2020553619A JP2021520344A5 JP 2021520344 A5 JP2021520344 A5 JP 2021520344A5 JP 2020553619 A JP2020553619 A JP 2020553619A JP 2020553619 A JP2020553619 A JP 2020553619A JP 2021520344 A5 JP2021520344 A5 JP 2021520344A5
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JP
Japan
Prior art keywords
lactic acid
gemcitabine
oligo
cancer
conjugate
Prior art date
Application number
JP2020553619A
Other languages
English (en)
Japanese (ja)
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JP2021520344A (ja
JPWO2019195164A5 (https=
JP7495352B2 (ja
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Priority claimed from PCT/US2019/025174 external-priority patent/WO2019195164A1/en
Publication of JP2021520344A publication Critical patent/JP2021520344A/ja
Publication of JPWO2019195164A5 publication Critical patent/JPWO2019195164A5/ja
Publication of JP2021520344A5 publication Critical patent/JP2021520344A5/ja
Application granted granted Critical
Publication of JP7495352B2 publication Critical patent/JP7495352B2/ja
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JP2020553619A 2018-04-02 2019-04-01 物理的安定性の向上および抗腫瘍効果の増強のためのミセルにおけるオリゴ乳酸コンジュゲートのステレオコンプレックス Active JP7495352B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862651365P 2018-04-02 2018-04-02
US62/651,365 2018-04-02
PCT/US2019/025174 WO2019195164A1 (en) 2018-04-02 2019-04-01 Stereocomplex of oligolactic acid conjugates in micelles for improved physical stability and enhanced antitumor efficacy

Publications (4)

Publication Number Publication Date
JP2021520344A JP2021520344A (ja) 2021-08-19
JPWO2019195164A5 JPWO2019195164A5 (https=) 2022-04-04
JP2021520344A5 true JP2021520344A5 (https=) 2022-04-04
JP7495352B2 JP7495352B2 (ja) 2024-06-04

Family

ID=66175512

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020553619A Active JP7495352B2 (ja) 2018-04-02 2019-04-01 物理的安定性の向上および抗腫瘍効果の増強のためのミセルにおけるオリゴ乳酸コンジュゲートのステレオコンプレックス

Country Status (6)

Country Link
US (2) US20210128736A1 (https=)
JP (1) JP7495352B2 (https=)
KR (1) KR20200139737A (https=)
CN (1) CN112105390A (https=)
CA (1) CA3095788A1 (https=)
WO (1) WO2019195164A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110652595B (zh) * 2019-10-21 2022-11-29 南通大学附属医院 一种聚亮氨酸-聚天冬氨酸嵌段共聚物立构复合载药胶束及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8416234D0 (en) 1984-06-26 1984-08-01 Ici Plc Biodegradable amphipathic copolymers
KR0180334B1 (ko) 1995-09-21 1999-03-20 김윤 블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법
JP5048690B2 (ja) * 2006-03-08 2012-10-17 クローズ 特に種子発芽および植物発生のための遅延性効果の農業処理剤
US8668919B2 (en) * 2009-03-03 2014-03-11 Abbott Cardiovascular Systems Inc. Polymer for creating hemocompatible surface
CN103599073A (zh) * 2013-11-15 2014-02-26 无锡中科光远生物材料有限公司 一种负载有靶向抗癌药物的plga微米颗粒的制备方法
CN104961786B (zh) * 2015-06-05 2018-09-25 苏州大学 基于吉西他滨结构的前体药物及其应用
ES2804251T3 (es) 2016-03-14 2021-02-05 Wisconsin Alumni Res Found Conjugados y micelas de ácido oligoláctico con eficacia anticáncer mejorada
WO2017201407A1 (en) * 2016-05-20 2017-11-23 Massachusetts Institute Of Technology Hydrogel particle of cystamine cross-linked dextran aldehyde containing imine conjugated doxorubicin and rgd peptide for chemotherapy

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