JP2021519306A5 - - Google Patents
Info
- Publication number
- JP2021519306A5 JP2021519306A5 JP2020551912A JP2020551912A JP2021519306A5 JP 2021519306 A5 JP2021519306 A5 JP 2021519306A5 JP 2020551912 A JP2020551912 A JP 2020551912A JP 2020551912 A JP2020551912 A JP 2020551912A JP 2021519306 A5 JP2021519306 A5 JP 2021519306A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- composition according
- mutations
- her2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862648629P | 2018-03-27 | 2018-03-27 | |
| US62/648,629 | 2018-03-27 | ||
| US201862688049P | 2018-06-21 | 2018-06-21 | |
| US62/688,049 | 2018-06-21 | ||
| PCT/US2019/024353 WO2019191279A2 (en) | 2018-03-27 | 2019-03-27 | Compounds with anti-tumor activity against cancer cells bearing her2 exon 19 mutations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021519306A JP2021519306A (ja) | 2021-08-10 |
| JP2021519306A5 true JP2021519306A5 (enExample) | 2022-04-01 |
| JP7386174B2 JP7386174B2 (ja) | 2023-11-24 |
Family
ID=68060750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551912A Active JP7386174B2 (ja) | 2018-03-27 | 2019-03-27 | Ｈｅｒ２エクソン１９変異を有するがん細胞に対する抗腫瘍活性を有する化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210361655A1 (enExample) |
| EP (1) | EP3773551B1 (enExample) |
| JP (1) | JP7386174B2 (enExample) |
| KR (1) | KR102899689B1 (enExample) |
| CN (1) | CN112088000A (enExample) |
| AU (1) | AU2019243738B2 (enExample) |
| BR (1) | BR112020019251A2 (enExample) |
| CA (1) | CA3094108A1 (enExample) |
| IL (1) | IL277373A (enExample) |
| MX (1) | MX2020010121A (enExample) |
| PH (1) | PH12020551495A1 (enExample) |
| RU (1) | RU2020134932A (enExample) |
| SG (1) | SG11202009498RA (enExample) |
| WO (1) | WO2019191279A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210107023A (ko) * | 2018-12-21 | 2021-08-31 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 암 치료를 위한 조합 요법 |
| US20220143023A1 (en) * | 2019-03-29 | 2022-05-12 | Board Of Regents, The University Of Texas System | Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 insertions |
| US12629375B2 (en) | 2019-03-29 | 2026-05-19 | Board Of Regents, The University Of Texas System | Compounds with anti-tumor activity against cancer cells bearing HER2 exon 21 insertions |
| JP7709384B2 (ja) * | 2019-04-17 | 2025-07-16 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | チロシンキナーゼ阻害剤耐性ｅｇｆｒ変異を有するがんに対する化合物 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824311A (en) | 1987-11-30 | 1998-10-20 | Trustees Of The University Of Pennsylvania | Treatment of tumors with monoclonal antibodies against oncogene antigens |
| US4870287A (en) | 1988-03-03 | 1989-09-26 | Loma Linda University Medical Center | Multi-station proton beam therapy system |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| US5851795A (en) | 1991-06-27 | 1998-12-22 | Bristol-Myers Squibb Company | Soluble CTLA4 molecules and uses thereof |
| US5846945A (en) | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
| US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
| JPH08506247A (ja) | 1993-07-09 | 1996-07-09 | アムジェン ボールダー インコーポレイテッド | 組換えｃｔｌａ４ポリペプチドおよびその製造方法 |
| GB9506466D0 (en) | 1994-08-26 | 1995-05-17 | Prolifix Ltd | Cell cycle regulated repressor and dna element |
| US5760395A (en) | 1996-04-18 | 1998-06-02 | Universities Research Assoc., Inc. | Method and apparatus for laser-controlled proton beam radiology |
| US5739169A (en) | 1996-05-31 | 1998-04-14 | Procept, Incorporated | Aromatic compounds for inhibiting immune response |
| US5869245A (en) | 1996-06-05 | 1999-02-09 | Fox Chase Cancer Center | Mismatch endonuclease and its use in identifying mutations in targeted polynucleotide strands |
| US5844905A (en) | 1996-07-09 | 1998-12-01 | International Business Machines Corporation | Extensions to distributed MAC protocols with collision avoidance using RTS/CTS exchange |
| EP0970128A1 (en) | 1997-03-21 | 2000-01-12 | Brigham And Women's Hospital | Immunotherapeutic ctla-4 binding peptides |
| US6723564B2 (en) | 1998-05-07 | 2004-04-20 | Sequenom, Inc. | IR MALDI mass spectrometry of nucleic acids using liquid matrices |
| ES2706547T3 (es) | 1998-12-23 | 2019-03-29 | Pfizer | Anticuerpos monoclonales humanos para CTLA-4 |
| NZ517202A (en) | 1999-08-24 | 2004-05-28 | Medarex Inc | Human CTLA-4 antibodies and their uses |
| US7605238B2 (en) | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| WO2003082210A2 (en) | 2002-03-26 | 2003-10-09 | Massachusetts Institute Of Technology | Targets, methods, and reagents for diagnosis and treatment of schizophrenia |
| US20060104968A1 (en) | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| US7871607B2 (en) | 2003-03-05 | 2011-01-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases |
| EP3530736A3 (en) | 2005-05-09 | 2019-11-06 | ONO Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics |
| TWI377944B (en) | 2007-06-05 | 2012-12-01 | Hanmi Holdings Co Ltd | Novel amide derivative for inhibiting the growth of cancer cells |
| PT2170959E (pt) | 2007-06-18 | 2014-01-07 | Merck Sharp & Dohme | Anticorpos para o receptor humano de morte programada pd-1 |
| PT2242773T (pt) | 2008-02-11 | 2017-09-15 | Cure Tech Ltd | Anticorpos monoclonais para o tratamento de tumores |
| US8168757B2 (en) | 2008-03-12 | 2012-05-01 | Merck Sharp & Dohme Corp. | PD-1 binding proteins |
| WO2010014784A2 (en) | 2008-08-01 | 2010-02-04 | Bristol-Myers Squibb Company | Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases |
| WO2010098788A2 (en) | 2008-08-25 | 2010-09-02 | Amplimmune, Inc. | Pd-i antagonists and methods for treating infectious disease |
| EP2504028A4 (en) | 2009-11-24 | 2014-04-09 | Amplimmune Inc | SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2 |
| EP3053932B1 (en) | 2010-02-19 | 2020-07-22 | Xencor, Inc. | Novel ctla4-ig immunoadhesins |
| KR101217526B1 (ko) | 2010-06-11 | 2013-01-02 | 한미사이언스 주식회사 | 아마이드 유도체 또는 이의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물 |
| US8828391B2 (en) * | 2011-05-17 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Method for EGFR directed combination treatment of non-small cell lung cancer |
| KR101317809B1 (ko) * | 2011-06-07 | 2013-10-16 | 한미약품 주식회사 | 암세포의 성장을 억제하는 아마이드 유도체 및 비금속염 활택제를 포함하는 약학 조성물 |
| JP2014022858A (ja) | 2012-07-17 | 2014-02-03 | Murata Mfg Co Ltd | 電力増幅器 |
| US9308236B2 (en) | 2013-03-15 | 2016-04-12 | Bristol-Myers Squibb Company | Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions |
| CN105682683A (zh) | 2013-08-02 | 2016-06-15 | 阿杜罗生物科技控股有限公司 | 结合cd27激动剂以及免疫检查点抑制以用于免疫刺激 |
| US20180057603A1 (en) * | 2013-08-09 | 2018-03-01 | The Trustees Of The University Of Pennsylvania | Combination of IFN-gamma with Anti-ERBB Antibody for the Treatment of Cancers |
| SMT202300039T1 (it) | 2013-09-13 | 2023-03-17 | Beigene Switzerland Gmbh | Anticorpi anti-pd1 e loro uso come terapia e per diagnostica |
| EP3699589A1 (en) * | 2014-12-12 | 2020-08-26 | Celcuity Inc. | Methods of measuring erbb signaling pathway activity to diagnose and treat cancer patients |
| CN107250108B (zh) * | 2015-02-05 | 2020-11-27 | 特尔诺沃有限公司 | 用于治疗癌症的irs/stat3双重调节剂与抗癌剂的组合 |
| BR112019010020A2 (pt) * | 2016-11-17 | 2019-08-20 | Univ Texas | compostos com atividade anti-tumoral contra células cancerosas contendo mutações de egfr ou her2 exon 20 |
| KR20190054826A (ko) * | 2017-11-14 | 2019-05-22 | 한미약품 주식회사 | 암의 포지오티닙 치료에 대한 반응을 나타내는 바이오마커 및 그의 용도 |
| KR20210107023A (ko) * | 2018-12-21 | 2021-08-31 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 암 치료를 위한 조합 요법 |
| WO2020136417A2 (en) * | 2018-12-27 | 2020-07-02 | Pratik Sharma | Manoeuvring subsystem of unmanned aerial vehicle |
-
2019
- 2019-03-27 JP JP2020551912A patent/JP7386174B2/ja active Active
- 2019-03-27 MX MX2020010121A patent/MX2020010121A/es unknown
- 2019-03-27 AU AU2019243738A patent/AU2019243738B2/en not_active Expired - Fee Related
- 2019-03-27 US US17/042,012 patent/US20210361655A1/en active Pending
- 2019-03-27 EP EP19775368.4A patent/EP3773551B1/en active Active
- 2019-03-27 BR BR112020019251-1A patent/BR112020019251A2/pt not_active IP Right Cessation
- 2019-03-27 RU RU2020134932A patent/RU2020134932A/ru unknown
- 2019-03-27 CN CN201980022143.3A patent/CN112088000A/zh active Pending
- 2019-03-27 CA CA3094108A patent/CA3094108A1/en active Pending
- 2019-03-27 WO PCT/US2019/024353 patent/WO2019191279A2/en not_active Ceased
- 2019-03-27 KR KR1020207029032A patent/KR102899689B1/ko active Active
- 2019-03-27 SG SG11202009498RA patent/SG11202009498RA/en unknown
-
2020
- 2020-09-15 IL IL277373A patent/IL277373A/en unknown
- 2020-09-17 PH PH12020551495A patent/PH12020551495A1/en unknown
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