JP2022529945A5 - - Google Patents

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Publication number
JP2022529945A5
JP2022529945A5 JP2021561673A JP2021561673A JP2022529945A5 JP 2022529945 A5 JP2022529945 A5 JP 2022529945A5 JP 2021561673 A JP2021561673 A JP 2021561673A JP 2021561673 A JP2021561673 A JP 2021561673A JP 2022529945 A5 JP2022529945 A5 JP 2022529945A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
composition according
mutations
egfr
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Granted
Application number
JP2021561673A
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English (en)
Japanese (ja)
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JP7709384B2 (ja
JP2022529945A (ja
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Priority claimed from PCT/US2020/028540 external-priority patent/WO2020214824A1/en
Publication of JP2022529945A publication Critical patent/JP2022529945A/ja
Publication of JP2022529945A5 publication Critical patent/JP2022529945A5/ja
Application granted granted Critical
Publication of JP7709384B2 publication Critical patent/JP7709384B2/ja
Active legal-status Critical Current
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JP2021561673A 2019-04-17 2020-04-16 チロシンキナーゼ阻害剤耐性egfr変異を有するがんに対する化合物 Active JP7709384B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962835343P 2019-04-17 2019-04-17
US62/835,343 2019-04-17
PCT/US2020/028540 WO2020214824A1 (en) 2019-04-17 2020-04-16 Compounds against cancer bearing tyrosine kinase inhibitor resistant egfr mutations

Publications (3)

Publication Number Publication Date
JP2022529945A JP2022529945A (ja) 2022-06-27
JP2022529945A5 true JP2022529945A5 (enExample) 2023-04-24
JP7709384B2 JP7709384B2 (ja) 2025-07-16

Family

ID=72837936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021561673A Active JP7709384B2 (ja) 2019-04-17 2020-04-16 チロシンキナーゼ阻害剤耐性egfr変異を有するがんに対する化合物

Country Status (13)

Country Link
US (1) US20220175779A1 (enExample)
EP (1) EP3956035A4 (enExample)
JP (1) JP7709384B2 (enExample)
KR (1) KR20220004089A (enExample)
CN (1) CN113993592A (enExample)
AU (1) AU2020257395A1 (enExample)
BR (1) BR112021020601A2 (enExample)
CA (1) CA3132819A1 (enExample)
IL (1) IL287115A (enExample)
MX (1) MX2021012705A (enExample)
PH (1) PH12021552579A1 (enExample)
SG (1) SG11202111120VA (enExample)
WO (1) WO2020214824A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202108311RA (en) 2019-02-26 2021-09-29 Janssen Biotech Inc Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
PH12021552798A1 (en) 2019-05-14 2022-09-19 Janssen Biotech Inc Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
JP7783182B2 (ja) 2020-02-12 2025-12-09 ヤンセン バイオテツク,インコーポレーテツド c-METエクソン14スキッピング変異を有する患者の治療
AU2022212123A1 (en) * 2021-01-29 2023-09-07 Board Of Regents, The University Of Texas System Methods of treating cancer with kinase inhibitors
JP2024505056A (ja) * 2021-01-29 2024-02-02 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム ポジオチニブを用いてがんを処置する方法
CA3242316A1 (en) 2021-12-30 2023-07-06 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of flt3
CN115998743B (zh) * 2023-01-16 2024-05-28 威尚(上海)生物医药有限公司 喹唑啉类化合物在克服奥希替尼耐药中的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3120851A1 (en) * 2015-07-21 2017-01-25 Pangaea Biotech S.L. 4-amino-6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8h)-one for treatment of solid cancers
US20190125751A1 (en) * 2016-05-18 2019-05-02 Boehringer Ingelheim International Gmbh Anticancer combination therapy
MA46852A (fr) * 2016-11-17 2019-09-25 Univ Texas Composés à activité antitumorale contre des cellules cancéreuses porteuses de mutations egfr ou her2 exon 20
WO2018213770A1 (en) * 2017-05-19 2018-11-22 Regents Of The University Of Minnesota Therapeutic methods
CA3094108A1 (en) * 2018-03-27 2019-10-03 Board Of Regents, The University Of Texas Systems Compounds with anti-tumor activity against cancer cells bearing her2 exon 19 mutations
CA3101657A1 (en) * 2018-06-25 2020-01-02 Spectrum Pharmaceuticals, Inc. Combination of poziotinib with cytotoxic agent and/or other molecularly targeted agent and use thereof
US20210346383A1 (en) * 2018-09-04 2021-11-11 Rain Therapeutics Inc. Compounds, compositions and methods for treating or preventing her-driven cancers
SG11202108311RA (en) * 2019-02-26 2021-09-29 Janssen Biotech Inc Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
PH12021552110A1 (en) * 2019-03-29 2022-06-06 Univ Texas Compounds with anti-tumor activity against cancer cells bearing her2 exon 21 insertions
AU2020254499A1 (en) * 2019-03-29 2021-10-28 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing EGFR or HER2 exon 20 insertions

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