JP2022529016A5 - - Google Patents

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Publication number
JP2022529016A5
JP2022529016A5 JP2021561677A JP2021561677A JP2022529016A5 JP 2022529016 A5 JP2022529016 A5 JP 2022529016A5 JP 2021561677 A JP2021561677 A JP 2021561677A JP 2021561677 A JP2021561677 A JP 2021561677A JP 2022529016 A5 JP2022529016 A5 JP 2022529016A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
composition according
egfr
tki
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021561677A
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English (en)
Japanese (ja)
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JP2022529016A (ja
JP7822597B2 (ja
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Priority claimed from PCT/US2020/028547 external-priority patent/WO2020214831A1/en
Publication of JP2022529016A publication Critical patent/JP2022529016A/ja
Publication of JP2022529016A5 publication Critical patent/JP2022529016A5/ja
Application granted granted Critical
Publication of JP7822597B2 publication Critical patent/JP7822597B2/ja
Active legal-status Critical Current
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JP2021561677A 2019-04-17 2020-04-16 チロシンキナーゼ阻害剤耐性egfr変異を有するがん細胞に対する抗腫瘍活性を有する化合物 Active JP7822597B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962835354P 2019-04-17 2019-04-17
US62/835,354 2019-04-17
PCT/US2020/028547 WO2020214831A1 (en) 2019-04-17 2020-04-16 Compounds with anti-tumor activity against cancer cells bearing tyrosine kinase inhibitor resistant egfr mutations

Publications (3)

Publication Number Publication Date
JP2022529016A JP2022529016A (ja) 2022-06-16
JP2022529016A5 true JP2022529016A5 (enExample) 2023-04-24
JP7822597B2 JP7822597B2 (ja) 2026-03-03

Family

ID=72837840

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021561677A Active JP7822597B2 (ja) 2019-04-17 2020-04-16 チロシンキナーゼ阻害剤耐性egfr変異を有するがん細胞に対する抗腫瘍活性を有する化合物

Country Status (7)

Country Link
US (1) US20220193074A1 (enExample)
EP (1) EP3955928A4 (enExample)
JP (1) JP7822597B2 (enExample)
KR (1) KR20220003546A (enExample)
CN (1) CN113784718A (enExample)
CA (1) CA3132816A1 (enExample)
WO (1) WO2020214831A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021010265A (es) 2019-02-26 2021-09-23 Janssen Biotech Inc Terapias de combinacion y estratificacion de pacientes con anticuerpos anti-egfr/c-met biespecificos.
US12629375B2 (en) 2019-03-29 2026-05-19 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing HER2 exon 21 insertions
MY208668A (en) 2019-05-14 2025-05-23 Janssen Biotech Inc Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
BR112022015140A2 (pt) 2020-02-12 2022-10-11 Janssen Biotech Inc Tratamento de pacientes que têm mutações de salto do éxon 14 de c-met
WO2023129667A1 (en) 2021-12-30 2023-07-06 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of flt3
CN120265328A (zh) * 2022-11-03 2025-07-04 德州大学系统董事会 用于非小细胞肺癌的检测和治疗的方法
CN115998743B (zh) * 2023-01-16 2024-05-28 威尚(上海)生物医药有限公司 喹唑啉类化合物在克服奥希替尼耐药中的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107530434A (zh) * 2015-04-23 2018-01-02 免疫医疗有限公司 非小细胞肺癌egfr突变阳性的联合疗法
BR112019010020A2 (pt) * 2016-11-17 2019-08-20 Univ Texas compostos com atividade anti-tumoral contra células cancerosas contendo mutações de egfr ou her2 exon 20
EP3585389A4 (en) * 2017-02-22 2020-12-23 G1 Therapeutics, Inc. EGFR-CAUSED CANCER TREATMENT WITH LESS SIDE EFFECTS

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