JP2021518384A5 - - Google Patents
Info
- Publication number
- JP2021518384A5 JP2021518384A5 JP2020550176A JP2020550176A JP2021518384A5 JP 2021518384 A5 JP2021518384 A5 JP 2021518384A5 JP 2020550176 A JP2020550176 A JP 2020550176A JP 2020550176 A JP2020550176 A JP 2020550176A JP 2021518384 A5 JP2021518384 A5 JP 2021518384A5
- Authority
- JP
- Japan
- Prior art keywords
- triazole
- dihydro
- aminomethyl
- fluoropropane
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023128580A JP2023145748A (ja) | 2018-03-21 | 2023-08-07 | 新規トリアゾロン誘導体またはその塩、およびこれらを含む医薬組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2018-0032548 | 2018-03-21 | ||
| KR1020180032548A KR20190110736A (ko) | 2018-03-21 | 2018-03-21 | 신규의 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| PCT/IB2019/052278 WO2019180646A1 (en) | 2018-03-21 | 2019-03-20 | Novel triazolone derivatives or salts thereof and pharmaceutical compositions comprising the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023128580A Division JP2023145748A (ja) | 2018-03-21 | 2023-08-07 | 新規トリアゾロン誘導体またはその塩、およびこれらを含む医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021518384A JP2021518384A (ja) | 2021-08-02 |
| JP2021518384A5 true JP2021518384A5 (enExample) | 2022-03-11 |
| JP7383627B2 JP7383627B2 (ja) | 2023-11-20 |
Family
ID=67986894
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550176A Active JP7383627B2 (ja) | 2018-03-21 | 2019-03-20 | 新規トリアゾロン誘導体またはその塩、およびこれらを含む医薬組成物 |
| JP2023128580A Pending JP2023145748A (ja) | 2018-03-21 | 2023-08-07 | 新規トリアゾロン誘導体またはその塩、およびこれらを含む医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023128580A Pending JP2023145748A (ja) | 2018-03-21 | 2023-08-07 | 新規トリアゾロン誘導体またはその塩、およびこれらを含む医薬組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10995086B2 (enExample) |
| EP (1) | EP3768675B1 (enExample) |
| JP (2) | JP7383627B2 (enExample) |
| KR (2) | KR20190110736A (enExample) |
| CN (1) | CN111886233B (enExample) |
| AR (1) | AR115007A1 (enExample) |
| AU (1) | AU2019237344B2 (enExample) |
| CA (1) | CA3093057A1 (enExample) |
| TW (1) | TWI803600B (enExample) |
| WO (1) | WO2019180646A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190110736A (ko) | 2018-03-21 | 2019-10-01 | 주식회사유한양행 | 신규의 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| KR20190110740A (ko) | 2018-03-21 | 2019-10-01 | 주식회사유한양행 | 신규의 아릴 또는 헤테로아릴 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| KR20200004036A (ko) | 2018-07-03 | 2020-01-13 | 주식회사유한양행 | (e)-(2-(클로로메틸)-3-플루오로알릴)카바메이트 유도체의 제조방법 |
| TW202039486A (zh) | 2018-12-14 | 2020-11-01 | 南韓商柳韓洋行股份有限公司 | 三唑并吡啶-3-酮化物或其鹽及包含彼之醫藥組合物 |
| TWI835945B (zh) | 2018-12-14 | 2024-03-21 | 南韓商柳韓洋行股份有限公司 | 3,3-二氟烯丙胺化物或其鹽及包含彼的醫藥組合物 |
| AU2020206477B2 (en) | 2019-01-11 | 2022-11-10 | Transthera Sciences (Nanjing), Inc. | Haloallylamine compounds and application thereof |
| KR20220145981A (ko) * | 2021-04-22 | 2022-11-01 | 주식회사유한양행 | 트리아졸론, 테트라졸론, 및 이미다졸론, 또는 그의 염, 및 그를 포함하는 제약 조성물 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2725148A1 (de) | 1977-06-03 | 1978-12-14 | Hoechst Ag | 1-aryl-4-alkyl-1,2,4-triazol-5-one und verfahren zu ihrer herstellung |
| WO2005014530A2 (en) | 2003-08-08 | 2005-02-17 | La Jolla Pharmaceutical Co. | Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment of diseases |
| KR100572996B1 (ko) | 2003-08-12 | 2006-04-25 | 한국화학연구원 | 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법 |
| AU2005216955A1 (en) | 2004-02-25 | 2005-09-09 | La Jolla Pharmaceutical Company | Amines and amides for the treatment of diseases |
| TW200726765A (en) | 2005-06-17 | 2007-07-16 | Bristol Myers Squibb Co | Triazolopyridine cannabinoid receptor 1 antagonists |
| US20070293548A1 (en) | 2006-03-31 | 2007-12-20 | Wang Eric Y | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases |
| EP2139333A4 (en) * | 2007-03-28 | 2010-11-10 | Merck Sharp & Dohme | SUBSTITUTED PYRID- [3,2-E] - [1,2,4] -TRIAZOL- [4,3-C] -PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS |
| WO2008119662A1 (en) | 2007-03-29 | 2008-10-09 | F. Hoffmann-La Roche Ag | Non-nucleoside reverse transcriptase inhibitors |
| GB0722075D0 (en) | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
| CN101917845A (zh) | 2007-11-21 | 2010-12-15 | 法马克西斯制药公司 | Ssao/vap-1的卤代烯丙胺抑制剂及其用途 |
| WO2010096722A1 (en) | 2009-02-20 | 2010-08-26 | Takeda Pharmaceutical Company Limited | 3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors |
| EP2822931B1 (en) | 2012-03-09 | 2017-05-03 | Inception 2, Inc. | Triazolone compounds and uses thereof |
| US9192617B2 (en) | 2012-03-20 | 2015-11-24 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
| AU2013255103B2 (en) | 2012-05-02 | 2016-09-29 | Syntara Limited | Substituted 3-haloallylamine inhibitors of SSAO and uses thereof |
| BR112015026631A2 (pt) * | 2013-04-25 | 2017-07-25 | Yuhan Corp | compostos ou sais farmaceuticamente aceitáveis dos mesmos e respectivos usos, composição farmacêutica e método para prevenir ou tratar diabetes melito em mamífero |
| US9758523B2 (en) | 2014-07-10 | 2017-09-12 | Incyte Corporation | Triazolopyridines and triazolopyrazines as LSD1 inhibitors |
| WO2016092375A1 (en) * | 2014-12-11 | 2016-06-16 | Zenith Epigenetics Corp. | Substituted heterocycles as bromodomain inhibitors |
| WO2016101119A1 (en) | 2014-12-23 | 2016-06-30 | Merck Sharp & Dohme Corp. | Fused heteroaryl derivatives as orexin receptor antagonists |
| TW201722958A (zh) * | 2015-09-15 | 2017-07-01 | 葛蘭素史克智慧財產（第二）有限公司 | 化學化合物 |
| EA201891674A1 (ru) | 2016-02-12 | 2019-01-31 | Фармаксис Лтд. | Ингибиторы лизилоксидаз, представляющие собой индольные и азаиндольные производные галогеналлиламина, и их применения |
| EP3452469A1 (en) | 2016-05-03 | 2019-03-13 | Bayer Pharma Aktiengesellschaft | Fluoroalkyl-substituted aryltriazole derivatives and uses thereof |
| WO2018027892A1 (en) | 2016-08-12 | 2018-02-15 | Eli Lilly And Company | Amino pyrimidine ssao inhibitors |
| US20210212968A1 (en) | 2016-10-19 | 2021-07-15 | Boehringer Ingelheim International Gmbh | Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof |
| EP3589619A4 (en) | 2017-03-02 | 2020-12-16 | Pharmaxis Ltd. | LYSYL OXIDASE INHIBITORS, HALOGENOALLYLAMINE PYRAZOLE DERIVATIVES AND THEIR USES |
| US20200087248A1 (en) | 2017-04-28 | 2020-03-19 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Fluoroallylamine Derivative And Use Thereof |
| AU2018287777B2 (en) | 2017-06-20 | 2020-05-21 | Shandong Danhong Pharmaceutical Co., Ltd. | SSAO inhibitor |
| CN109810041B (zh) | 2017-11-21 | 2023-08-15 | 药捷安康(南京)科技股份有限公司 | 卤代烯丙基胺类ssao/vap-1抑制剂及其应用 |
| CN109988109B (zh) | 2017-12-29 | 2020-12-29 | 广东东阳光药业有限公司 | 抑制ssao/vap-1的胺类化合物及其用途 |
| KR20190110736A (ko) * | 2018-03-21 | 2019-10-01 | 주식회사유한양행 | 신규의 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| KR20190110740A (ko) | 2018-03-21 | 2019-10-01 | 주식회사유한양행 | 신규의 아릴 또는 헤테로아릴 트라이아졸론 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| CN110938059A (zh) | 2018-09-25 | 2020-03-31 | 上海轶诺药业有限公司 | 胺基脲敏感性胺氧化酶抑制剂制备及其应用 |
| WO2020063854A1 (zh) | 2018-09-27 | 2020-04-02 | 南京明德新药研发有限公司 | 作为vap-1抑制剂的喹啉类衍生物 |
| CA3114166A1 (en) | 2018-09-28 | 2020-04-02 | Acucela Inc. | Inhibitors of vap-1 |
| MX2021003559A (es) | 2018-09-28 | 2021-08-24 | Acucela Inc | Inhibidores de vap-1. |
| CN112789277B (zh) | 2018-10-22 | 2022-11-04 | 广东东阳光药业有限公司 | 胍类衍生物及其用途 |
| EP3870162A4 (en) | 2018-10-24 | 2022-08-24 | Metacrine, Inc. | SSAO INHIBITORS AND USES THEREOF |
| TW202039486A (zh) | 2018-12-14 | 2020-11-01 | 南韓商柳韓洋行股份有限公司 | 三唑并吡啶-3-酮化物或其鹽及包含彼之醫藥組合物 |
| TWI835945B (zh) | 2018-12-14 | 2024-03-21 | 南韓商柳韓洋行股份有限公司 | 3,3-二氟烯丙胺化物或其鹽及包含彼的醫藥組合物 |
| AU2020206477B2 (en) | 2019-01-11 | 2022-11-10 | Transthera Sciences (Nanjing), Inc. | Haloallylamine compounds and application thereof |
-
2018
- 2018-03-21 KR KR1020180032548A patent/KR20190110736A/ko active Pending
-
2019
- 2019-03-20 WO PCT/IB2019/052278 patent/WO2019180646A1/en not_active Ceased
- 2019-03-20 JP JP2020550176A patent/JP7383627B2/ja active Active
- 2019-03-20 CN CN201980020696.5A patent/CN111886233B/zh active Active
- 2019-03-20 AU AU2019237344A patent/AU2019237344B2/en not_active Ceased
- 2019-03-20 EP EP19772403.2A patent/EP3768675B1/en active Active
- 2019-03-20 KR KR1020207029750A patent/KR102788118B1/ko active Active
- 2019-03-20 CA CA3093057A patent/CA3093057A1/en active Pending
- 2019-03-20 US US16/359,985 patent/US10995086B2/en active Active
- 2019-03-21 TW TW108109864A patent/TWI803600B/zh not_active IP Right Cessation
- 2019-03-21 AR ARP190100713A patent/AR115007A1/es not_active Application Discontinuation
-
2021
- 2021-03-22 US US17/208,887 patent/US11780830B2/en active Active
-
2023
- 2023-08-07 JP JP2023128580A patent/JP2023145748A/ja active Pending
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