JP2021514385A5 - - Google Patents
Info
- Publication number
- JP2021514385A5 JP2021514385A5 JP2020565534A JP2020565534A JP2021514385A5 JP 2021514385 A5 JP2021514385 A5 JP 2021514385A5 JP 2020565534 A JP2020565534 A JP 2020565534A JP 2020565534 A JP2020565534 A JP 2020565534A JP 2021514385 A5 JP2021514385 A5 JP 2021514385A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- group
- halogen
- heterocycloalkyl
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18305134.1 | 2018-02-08 | ||
| EP18305134 | 2018-02-08 | ||
| PCT/EP2019/053081 WO2019154956A1 (en) | 2018-02-08 | 2019-02-08 | Non-fused thiophene derivatives and their uses |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021514385A JP2021514385A (ja) | 2021-06-10 |
| JP2021514385A5 true JP2021514385A5 (https=) | 2022-02-15 |
| JPWO2019154956A5 JPWO2019154956A5 (https=) | 2022-02-15 |
| JP7399110B2 JP7399110B2 (ja) | 2023-12-15 |
Family
ID=61283124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020565534A Active JP7399110B2 (ja) | 2018-02-08 | 2019-02-08 | 非縮合チオフェン誘導体及びそれらの使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11767316B2 (https=) |
| EP (2) | EP3749649A1 (https=) |
| JP (1) | JP7399110B2 (https=) |
| KR (2) | KR102871188B1 (https=) |
| CN (1) | CN111936471B (https=) |
| AU (1) | AU2019219123B2 (https=) |
| BR (1) | BR112020015743A2 (https=) |
| CA (1) | CA3087830A1 (https=) |
| CO (1) | CO2020009106A2 (https=) |
| EA (1) | EA202091897A1 (https=) |
| IL (1) | IL275893B2 (https=) |
| MX (1) | MX2020007917A (https=) |
| PH (1) | PH12020551175A1 (https=) |
| SG (1) | SG11202006723SA (https=) |
| WO (2) | WO2019154953A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020015743A2 (pt) | 2018-02-08 | 2020-12-15 | Enyo Pharma | Derivados de tiofeno não fundido e seus usos |
| MX2020007918A (es) | 2018-02-08 | 2020-12-03 | Enyo Pharma | Derivados fusionados de tiofeno y sus usos. |
| CN114555577A (zh) * | 2019-10-17 | 2022-05-27 | 埃尼奥制药公司 | 用于治疗门静脉炎症和纤维化的噻吩衍生物 |
| CA3164134A1 (en) | 2019-12-06 | 2021-06-10 | Vertex Pharmaceuticals Incorporated | Substituted tetrahydrofurans as modulators of sodium channels |
| AU2021224588B2 (en) | 2020-02-18 | 2024-07-18 | Gilead Sciences, Inc. | Antiviral compounds |
| TWI775313B (zh) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| WO2022020714A1 (en) * | 2020-07-24 | 2022-01-27 | Inipharm, Inc. | Thiophene hsd17b13 inhibitors and uses thereof |
| EP4192448A1 (en) | 2020-08-05 | 2023-06-14 | ENYO Pharma | Thiophen compounds for use in the treatment of renal fibrosis |
| CN116670118B (zh) | 2020-11-13 | 2026-02-06 | 伊尼制药公司 | 二氯苯酚hsd17b13抑制剂及其用途 |
| CN112851633B (zh) * | 2021-01-19 | 2021-12-07 | 上海应用技术大学 | 一种2-氨基噻吩类神经氨酸酶抑制剂及其制备方法与应用 |
| EP4323362B1 (en) | 2021-04-16 | 2025-05-07 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
| SI4347031T1 (sl) | 2021-06-04 | 2026-01-30 | Vertex Pharmaceuticals Incorporated | N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov |
| AU2022328698B2 (en) | 2021-08-18 | 2025-02-20 | Gilead Sciences, Inc. | Phospholipid compounds and methods of making and using the same |
| WO2024037604A1 (zh) * | 2022-08-17 | 2024-02-22 | 彭光浩 | 基于多种碳氮代谢途径的分枝杆菌、分离方法及用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9924092D0 (en) | 1999-10-13 | 1999-12-15 | Zeneca Ltd | Pyrimidine derivatives |
| US20050085531A1 (en) * | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
| DE10359791A1 (de) * | 2003-12-19 | 2005-07-21 | Bayer Healthcare Ag | Substituierte Thiophene |
| JP5411141B2 (ja) * | 2007-09-10 | 2014-02-12 | カルシメディカ，インク． | 細胞内カルシウムを調節する化合物 |
| US8389567B2 (en) | 2007-12-12 | 2013-03-05 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US7906553B2 (en) * | 2008-08-27 | 2011-03-15 | Calcimedica, Inc. | Substituted thiophene modulators of intracellular calcium |
| US20110319416A1 (en) | 2009-01-28 | 2011-12-29 | Emory University | Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions |
| WO2011097607A1 (en) * | 2010-02-08 | 2011-08-11 | Southern Research Institute | Anti-viral treatment and assay to screen for anti-viral agent |
| US20150126519A1 (en) * | 2012-03-20 | 2015-05-07 | Fred Hutchinson Cancer Research Center | Antibiotic compounds and compositions, and methods for identification thereof |
| EP2679591A1 (en) * | 2012-06-29 | 2014-01-01 | Poxel | Thienopyridone derivatives useful as activators of AMPK |
| WO2015187827A1 (en) | 2014-06-03 | 2015-12-10 | The Trustees Of The University Of Pennsylvania | Novel effective antiviral compounds and methods using same |
| TW201607930A (zh) | 2014-07-18 | 2016-03-01 | 百濟神州有限公司 | 作為ｔ７９０ｍ／ｗｔ－ｅｇｆｒ的選擇性和不可逆的激酶抑制劑的５－氨基－４－氨甲醯基－吡唑化合物及其用途 |
| KR20190098204A (ko) | 2016-12-29 | 2019-08-21 | 엔요 파마 | 항바이러스제로서의 티오펜 유도체 |
| BR112020015743A2 (pt) | 2018-02-08 | 2020-12-15 | Enyo Pharma | Derivados de tiofeno não fundido e seus usos |
| MX2020007918A (es) | 2018-02-08 | 2020-12-03 | Enyo Pharma | Derivados fusionados de tiofeno y sus usos. |
| WO2019154958A1 (en) | 2018-02-08 | 2019-08-15 | Enyo Pharma | Use of modulators of neet proteins for the treatment of infection |
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2019
- 2019-02-08 BR BR112020015743-0A patent/BR112020015743A2/pt not_active IP Right Cessation
- 2019-02-08 EP EP19703332.7A patent/EP3749649A1/en not_active Withdrawn
- 2019-02-08 EP EP19703333.5A patent/EP3749650A1/en active Pending
- 2019-02-08 EA EA202091897A patent/EA202091897A1/ru unknown
- 2019-02-08 JP JP2020565534A patent/JP7399110B2/ja active Active
- 2019-02-08 CN CN201980012287.0A patent/CN111936471B/zh active Active
- 2019-02-08 IL IL275893A patent/IL275893B2/en unknown
- 2019-02-08 CA CA3087830A patent/CA3087830A1/en active Pending
- 2019-02-08 SG SG11202006723SA patent/SG11202006723SA/en unknown
- 2019-02-08 WO PCT/EP2019/053077 patent/WO2019154953A1/en not_active Ceased
- 2019-02-08 US US16/967,744 patent/US11767316B2/en active Active
- 2019-02-08 KR KR1020247027773A patent/KR102871188B1/ko active Active
- 2019-02-08 US US16/967,753 patent/US11840527B2/en active Active
- 2019-02-08 AU AU2019219123A patent/AU2019219123B2/en not_active Ceased
- 2019-02-08 KR KR1020207023770A patent/KR20200141026A/ko not_active Ceased
- 2019-02-08 WO PCT/EP2019/053081 patent/WO2019154956A1/en not_active Ceased
- 2019-02-08 MX MX2020007917A patent/MX2020007917A/es unknown
-
2020
- 2020-07-24 CO CONC2020/0009106A patent/CO2020009106A2/es unknown
- 2020-08-03 PH PH12020551175A patent/PH12020551175A1/en unknown