JP2024506530A5 - - Google Patents

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Publication number
JP2024506530A5
JP2024506530A5 JP2023545262A JP2023545262A JP2024506530A5 JP 2024506530 A5 JP2024506530 A5 JP 2024506530A5 JP 2023545262 A JP2023545262 A JP 2023545262A JP 2023545262 A JP2023545262 A JP 2023545262A JP 2024506530 A5 JP2024506530 A5 JP 2024506530A5
Authority
JP
Japan
Prior art keywords
group
alkyl
aryl
heterocyclyl
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023545262A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024506530A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/051650 external-priority patent/WO2022157392A1/en
Publication of JP2024506530A publication Critical patent/JP2024506530A/ja
Publication of JP2024506530A5 publication Critical patent/JP2024506530A5/ja
Pending legal-status Critical Current

Links

JP2023545262A 2021-01-25 2022-01-25 フェロトーシス制御性細胞死の阻害剤としてのインドール、6-および7-アザインドール誘導体の使用 Pending JP2024506530A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21305085.9 2021-01-25
EP21305085 2021-01-25
PCT/EP2022/051650 WO2022157392A1 (en) 2021-01-25 2022-01-25 Use of indole, 6- and 7-azaindole derivatives as inhibitors of ferroptosis regulated cell death

Publications (2)

Publication Number Publication Date
JP2024506530A JP2024506530A (ja) 2024-02-14
JP2024506530A5 true JP2024506530A5 (https=) 2025-01-31

Family

ID=74553738

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023545262A Pending JP2024506530A (ja) 2021-01-25 2022-01-25 フェロトーシス制御性細胞死の阻害剤としてのインドール、6-および7-アザインドール誘導体の使用

Country Status (6)

Country Link
US (1) US20240116923A1 (https=)
EP (1) EP4281070A1 (https=)
JP (1) JP2024506530A (https=)
CN (1) CN117529317A (https=)
CA (1) CA3205853A1 (https=)
WO (1) WO2022157392A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250127084A (ko) 2022-12-02 2025-08-26 시비라이프 조절된 괴사 억제제와 n-아세틸시스테인의 상승작용적 조합
WO2025078659A1 (en) 2023-10-12 2025-04-17 Seabelife Method and kit for inducing cell differentiation, and regulated necrotic cell death inhibitor for use for regenerating damaged tissues
WO2025206255A1 (ja) * 2024-03-29 2025-10-02 富士フイルム株式会社 被験物質の評価方法および被験物質の評価キット

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011248175A1 (en) * 2010-05-06 2012-10-25 Merck Sharp & Dohme Corp. Aza-Indole derivatives useful as modulators of FAAH
WO2017054216A1 (zh) * 2015-10-01 2017-04-06 史利利 电磁炉及线圈盘
WO2017064216A1 (en) * 2015-10-13 2017-04-20 Institut National De La Sante Et De La Recherche Medicale (Inserm) N1- and n7-substituted sibiriline derivatives and their use as inhibitor of cellular necroptosis
ES2885474T3 (es) * 2015-10-13 2021-12-13 Inst Nat Sante Rech Med Derivados de sibirilina para la utilización en la prevención y/o tratamiento de trastornos asociados a la necroptosis celular
WO2019106434A1 (en) * 2017-12-01 2019-06-06 Collaborative Medicinal Development Pty. Ltd. Heterobicyclic aromatic derivatives for the treatment of ferroptosis-related disorders
AU2019390478A1 (en) * 2018-11-27 2021-07-08 The Trustees Of Columbia University In The City Of New York Compounds, compositions, and methods for modulating ferroptosis and treating excitotoxic disorders
BR112021017831A2 (pt) * 2019-03-11 2021-11-30 Collaborative Medicinal Dev Llc Derivados heteroaromáticos e aromáticos heterobicíclicos para o tratamento de distúrbios relacionados com ferroptose

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