JP2020523351A5 - - Google Patents

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Publication number
JP2020523351A5
JP2020523351A5 JP2019568599A JP2019568599A JP2020523351A5 JP 2020523351 A5 JP2020523351 A5 JP 2020523351A5 JP 2019568599 A JP2019568599 A JP 2019568599A JP 2019568599 A JP2019568599 A JP 2019568599A JP 2020523351 A5 JP2020523351 A5 JP 2020523351A5
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JP
Japan
Prior art keywords
alkyl
formula
heterocycloalkyl
cycloalkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2019568599A
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English (en)
Japanese (ja)
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JP2020523351A (ja
JP7257338B2 (ja
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Publication date
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Priority claimed from PCT/US2018/037503 external-priority patent/WO2018232094A1/en
Publication of JP2020523351A publication Critical patent/JP2020523351A/ja
Publication of JP2020523351A5 publication Critical patent/JP2020523351A5/ja
Priority to JP2023060086A priority Critical patent/JP7636460B2/ja
Application granted granted Critical
Publication of JP7257338B2 publication Critical patent/JP7257338B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019568599A 2017-06-15 2018-06-14 Ａｌｋ２キナーゼのイミダゾール含有阻害剤 Active JP7257338B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023060086A JP7636460B2 (ja) 2017-06-15 2023-04-03 Ａｌｋ２キナーゼのイミダゾール含有阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762520150P 2017-06-15 2017-06-15
US62/520,150 2017-06-15
PCT/US2018/037503 WO2018232094A1 (en) 2017-06-15 2018-06-14 Imidazole-containing inhibitors of alk2 kinase

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023060086A Division JP7636460B2 (ja) 2017-06-15 2023-04-03 Ａｌｋ２キナーゼのイミダゾール含有阻害剤

Publications (3)

Publication Number Publication Date
JP2020523351A JP2020523351A (ja) 2020-08-06
JP2020523351A5 true JP2020523351A5 (https=) 2021-07-26
JP7257338B2 JP7257338B2 (ja) 2023-04-13

Family

ID=64659499

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019568599A Active JP7257338B2 (ja) 2017-06-15 2018-06-14 Ａｌｋ２キナーゼのイミダゾール含有阻害剤
JP2023060086A Active JP7636460B2 (ja) 2017-06-15 2023-04-03 Ａｌｋ２キナーゼのイミダゾール含有阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023060086A Active JP7636460B2 (ja) 2017-06-15 2023-04-03 Ａｌｋ２キナーゼのイミダゾール含有阻害剤

Country Status (21)

Country Link
US (3) US11661426B2 (https=)
EP (1) EP3638229A4 (https=)
JP (2) JP7257338B2 (https=)
KR (2) KR20240063970A (https=)
CN (2) CN119060060A (https=)
AR (1) AR112027A1 (https=)
AU (2) AU2018283053C1 (https=)
BR (1) BR112019026517A2 (https=)
CA (1) CA3066164A1 (https=)
CL (1) CL2019003669A1 (https=)
CO (1) CO2020000194A2 (https=)
EA (1) EA202090052A1 (https=)
IL (2) IL312670B2 (https=)
MA (1) MA49401A (https=)
MX (2) MX2019015226A (https=)
MY (1) MY204609A (https=)
NZ (1) NZ800669A (https=)
PH (1) PH12019502781A1 (https=)
SG (1) SG10202112496SA (https=)
TW (1) TWI833696B (https=)
WO (1) WO2018232094A1 (https=)

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KR20220140515A (ko) 2020-01-13 2022-10-18 버지 애널리틱스, 인크. 치환된 피라졸로-피리미딘 및 그의 용도
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US12508262B2 (en) 2020-04-30 2025-12-30 Keros Therapeutics, Inc. Methods of using ALK2 inhibitors
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
IL303812A (en) * 2020-12-21 2023-08-01 Biocryst Pharm Inc Dosing regimens for oral ALK2 kinase inhibitors
EP4346806A4 (en) * 2021-05-25 2025-07-23 Biocryst Pharm Inc IMIDAZOLE-CONTAINING ALK2 KINASE INHIBITORS
WO2023107705A1 (en) 2021-12-10 2023-06-15 Incyte Corporation Bicyclic amines as cdk12 inhibitors
AU2023249795A1 (en) 2022-04-08 2024-10-17 Shy Therapeutics, Llc Compounds that interact with ras superfamily proteins for treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
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WO2025240752A1 (en) * 2024-05-15 2025-11-20 University Of Miami Mmp-13 antagonists

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