JP2021514384A5 - - Google Patents
Info
- Publication number
- JP2021514384A5 JP2021514384A5 JP2020565533A JP2020565533A JP2021514384A5 JP 2021514384 A5 JP2021514384 A5 JP 2021514384A5 JP 2020565533 A JP2020565533 A JP 2020565533A JP 2020565533 A JP2020565533 A JP 2020565533A JP 2021514384 A5 JP2021514384 A5 JP 2021514384A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- group
- alkyloxy
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18305133.3 | 2018-02-08 | ||
| EP18305133 | 2018-02-08 | ||
| PCT/EP2019/053074 WO2019154950A1 (en) | 2018-02-08 | 2019-02-08 | Fused thiophene derivatives and their uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021514384A JP2021514384A (ja) | 2021-06-10 |
| JP2021514384A5 true JP2021514384A5 (https=) | 2022-02-15 |
| JP7399109B2 JP7399109B2 (ja) | 2023-12-15 |
Family
ID=61283123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020565533A Active JP7399109B2 (ja) | 2018-02-08 | 2019-02-08 | 縮合チオフェン誘導体及びそれらの使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11492347B2 (https=) |
| EP (2) | EP3749658A1 (https=) |
| JP (1) | JP7399109B2 (https=) |
| KR (1) | KR20200141436A (https=) |
| CN (1) | CN111954668A (https=) |
| AU (1) | AU2019216793B2 (https=) |
| BR (1) | BR112020015907A2 (https=) |
| CA (1) | CA3087829A1 (https=) |
| EA (1) | EA202091889A1 (https=) |
| IL (1) | IL275905A (https=) |
| MX (1) | MX2020007918A (https=) |
| WO (2) | WO2019154949A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX388576B (es) | 2016-06-07 | 2025-03-20 | Jacobio Pharmaceuticals Co Ltd | Derivados heterociclicos novedosos utiles como inhibidores de shp2. |
| EA202190196A1 (ru) | 2017-03-23 | 2021-08-31 | Джакобио Фармасьютикалс Ко., Лтд. | Новые гетероциклические производные, применимые в качестве ингибиторов shp2 |
| CA3087830A1 (en) | 2018-02-08 | 2019-08-15 | Enyo Pharma | Non-fused thiophene derivatives and their uses |
| EA202091889A1 (ru) | 2018-02-08 | 2020-10-29 | Энио Фарма | Конденсированные производные тиофена и их применение |
| US20210393623A1 (en) | 2018-09-26 | 2021-12-23 | Jacobio Pharmaceuticals Co., Ltd. | Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors |
| WO2020210582A1 (en) * | 2019-04-11 | 2020-10-15 | University Of The Sciences | Allosteric agonists and positive allosteric modulators of glucagon-like peptide 1 receptor |
| RU2756587C9 (ru) * | 2021-02-12 | 2021-10-12 | Акционерное общество "Отисифарм" | Производные 2-ацетамидо-6-гидрокси-бензотиофена и их фармацевтически приемлемые соли, обладающие противовирусной активностью |
| CA3211099A1 (en) * | 2021-02-16 | 2022-08-25 | Hadasit Medical Research Services And Development Ltd. | Lysosome-associated membrane protein targeting compounds and uses thereof |
| TWI815475B (zh) * | 2021-05-27 | 2023-09-11 | 財團法人國家衛生研究院 | Ｃｄｇｓｈ鐵硫結構域２活化劑及其用途 |
| CN113264917B (zh) * | 2021-05-28 | 2022-07-01 | 华南理工大学 | 一种抗乙肝病毒化合物及其制备方法和应用 |
| CN113501807A (zh) * | 2021-06-10 | 2021-10-15 | 重庆科技学院 | 四氢苯并噻吩类化合物及药物组合物的制备方法和用途 |
| WO2023114761A2 (en) * | 2021-12-14 | 2023-06-22 | West Virginia University Board of Governors on behalf of West Virginia University | Targeting ero1 alpha with aurone derivatives |
| CN114891013A (zh) * | 2022-05-06 | 2022-08-12 | 南方科技大学 | 三尖杉碱类化合物的衍生物及其制备方法、药物组合物和用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2281925A1 (en) * | 1997-02-26 | 1998-09-03 | Ciblex Corporation | Inhibitors of leaderless protein export |
| US20040171603A1 (en) | 2001-05-18 | 2004-09-02 | Janos Pato | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor |
| WO2005023818A2 (en) | 2003-09-10 | 2005-03-17 | Gpc Biotech Ag | Heterobicyclic compounds as pharmaceutically active agents |
| WO2006093518A2 (en) * | 2004-06-25 | 2006-09-08 | Apath, Llc | Thienyl compounds for treating virus-related conditions |
| WO2006044826A2 (en) | 2004-10-20 | 2006-04-27 | Compass Pharmaceuticals Llc | Thiophens and their use as anti-tumor agents |
| WO2009026172A2 (en) * | 2007-08-17 | 2009-02-26 | The Regents Of The University Of California | New approach for designing diabetes drugs |
| US20110015239A1 (en) * | 2007-12-14 | 2011-01-20 | The Regents Of The University Of California | Inhibitors of calcium-activated chloride channels |
| US20110319416A1 (en) * | 2009-01-28 | 2011-12-29 | Emory University | Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions |
| US20130085133A1 (en) * | 2010-02-08 | 2013-04-04 | Sourthern Research Institute Office of Commercialization and Intellectual Prop. | Anti-viral treatment and assay to screenfor anti-viral agent |
| US8765803B1 (en) * | 2011-03-02 | 2014-07-01 | Stc.Unm | Rab7 GTPase inhibitors and related methods of treatment |
| WO2012148889A1 (en) * | 2011-04-28 | 2012-11-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibitors of human apurinic/apyrimidinic endonuclease 1 |
| EA201590197A1 (ru) | 2012-08-23 | 2015-07-30 | Алиос Биофарма, Инк. | Соединения для лечения парамиксовирусных вирусных инфекций |
| JP2014169257A (ja) * | 2013-03-05 | 2014-09-18 | Kyowa Hakko Kirin Co Ltd | 縮環チオフェン誘導体 |
| US10647725B2 (en) * | 2016-04-21 | 2020-05-12 | The University Of Toledo | Anti-infective 2-aminothiophenes |
| EP3562818B1 (en) | 2016-12-29 | 2022-05-18 | ENYO Pharma | Thiophene derivatives as antiviral agents |
| CA3087830A1 (en) | 2018-02-08 | 2019-08-15 | Enyo Pharma | Non-fused thiophene derivatives and their uses |
| US20210038566A1 (en) | 2018-02-08 | 2021-02-11 | Enyo Pharma | Use of modulators of neet proteins for the treatment of infection |
| EA202091889A1 (ru) | 2018-02-08 | 2020-10-29 | Энио Фарма | Конденсированные производные тиофена и их применение |
-
2019
- 2019-02-08 EA EA202091889A patent/EA202091889A1/ru unknown
- 2019-02-08 CN CN201980012508.4A patent/CN111954668A/zh active Pending
- 2019-02-08 EP EP19703105.7A patent/EP3749658A1/en not_active Withdrawn
- 2019-02-08 MX MX2020007918A patent/MX2020007918A/es unknown
- 2019-02-08 WO PCT/EP2019/053072 patent/WO2019154949A1/en not_active Ceased
- 2019-02-08 CA CA3087829A patent/CA3087829A1/en active Pending
- 2019-02-08 BR BR112020015907-7A patent/BR112020015907A2/pt not_active Application Discontinuation
- 2019-02-08 KR KR1020207023774A patent/KR20200141436A/ko not_active Ceased
- 2019-02-08 JP JP2020565533A patent/JP7399109B2/ja active Active
- 2019-02-08 WO PCT/EP2019/053074 patent/WO2019154950A1/en not_active Ceased
- 2019-02-08 AU AU2019216793A patent/AU2019216793B2/en not_active Ceased
- 2019-02-08 US US16/967,746 patent/US11492347B2/en active Active
- 2019-02-08 US US16/967,751 patent/US11603368B2/en active Active
- 2019-02-08 EP EP19703106.5A patent/EP3749659A1/en not_active Withdrawn
-
2020
- 2020-07-07 IL IL275905A patent/IL275905A/en unknown
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