JP2021513529A5 - - Google Patents

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Publication number
JP2021513529A5
JP2021513529A5 JP2020542626A JP2020542626A JP2021513529A5 JP 2021513529 A5 JP2021513529 A5 JP 2021513529A5 JP 2020542626 A JP2020542626 A JP 2020542626A JP 2020542626 A JP2020542626 A JP 2020542626A JP 2021513529 A5 JP2021513529 A5 JP 2021513529A5
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JP
Japan
Prior art keywords
alpha
liposome
composition according
polyglutamine
methyl
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Granted
Application number
JP2020542626A
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English (en)
Japanese (ja)
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JP7487107B2 (ja
JP2021513529A (ja
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Priority claimed from PCT/US2019/017002 external-priority patent/WO2019157146A1/en
Publication of JP2021513529A publication Critical patent/JP2021513529A/ja
Publication of JP2021513529A5 publication Critical patent/JP2021513529A5/ja
Priority to JP2024075984A priority Critical patent/JP7679114B2/ja
Application granted granted Critical
Publication of JP7487107B2 publication Critical patent/JP7487107B2/ja
Priority to JP2025072834A priority patent/JP2025107218A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020542626A 2018-02-07 2019-02-07 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用 Active JP7487107B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024075984A JP7679114B2 (ja) 2018-02-07 2024-05-08 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用
JP2025072834A JP2025107218A (ja) 2018-02-07 2025-04-25 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用

Applications Claiming Priority (41)

Application Number Priority Date Filing Date Title
US201862627703P 2018-02-07 2018-02-07
US201862627716P 2018-02-07 2018-02-07
US201862627741P 2018-02-07 2018-02-07
US201862627731P 2018-02-07 2018-02-07
US201862627714P 2018-02-07 2018-02-07
US62/627,731 2018-02-07
US62/627,714 2018-02-07
US62/627,741 2018-02-07
US62/627,716 2018-02-07
US62/627,703 2018-02-07
US201862630744P 2018-02-14 2018-02-14
US201862630728P 2018-02-14 2018-02-14
US201862630671P 2018-02-14 2018-02-14
US201862630637P 2018-02-14 2018-02-14
US201862630713P 2018-02-14 2018-02-14
US201862630820P 2018-02-14 2018-02-14
US201862630825P 2018-02-14 2018-02-14
US201862630634P 2018-02-14 2018-02-14
US201862630629P 2018-02-14 2018-02-14
US62/630,820 2018-02-14
US62/630,637 2018-02-14
US62/630,713 2018-02-14
US62/630,634 2018-02-14
US62/630,629 2018-02-14
US62/630,744 2018-02-14
US62/630,671 2018-02-14
US62/630,728 2018-02-14
US62/630,825 2018-02-14
US201862636294P 2018-02-28 2018-02-28
US62/636,294 2018-02-28
US201862662374P 2018-04-25 2018-04-25
US62/662,374 2018-04-25
US201862702732P 2018-07-24 2018-07-24
US201862702561P 2018-07-24 2018-07-24
US62/702,561 2018-07-24
US62/702,732 2018-07-24
US201862764943P 2018-08-17 2018-08-17
US201862764955P 2018-08-17 2018-08-17
US62/764,943 2018-08-17
US62/764,955 2018-08-17
PCT/US2019/017002 WO2019157146A1 (en) 2018-02-07 2019-02-07 Alpha polyglutamated antifolates and uses thereof

Related Child Applications (1)

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JP2024075984A Division JP7679114B2 (ja) 2018-02-07 2024-05-08 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用

Publications (3)

Publication Number Publication Date
JP2021513529A JP2021513529A (ja) 2021-05-27
JP2021513529A5 true JP2021513529A5 (enExample) 2022-02-16
JP7487107B2 JP7487107B2 (ja) 2024-05-20

Family

ID=67549609

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020542626A Active JP7487107B2 (ja) 2018-02-07 2019-02-07 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用
JP2024075984A Active JP7679114B2 (ja) 2018-02-07 2024-05-08 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用
JP2025072834A Pending JP2025107218A (ja) 2018-02-07 2025-04-25 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用

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JP2024075984A Active JP7679114B2 (ja) 2018-02-07 2024-05-08 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用
JP2025072834A Pending JP2025107218A (ja) 2018-02-07 2025-04-25 アルファポリグルタミン酸化葉酸代謝拮抗薬およびその使用

Country Status (6)

Country Link
US (2) US12076402B2 (enExample)
EP (1) EP3749313A4 (enExample)
JP (3) JP7487107B2 (enExample)
CN (1) CN111867593A (enExample)
CA (1) CA3090500A1 (enExample)
WO (1) WO2019157146A1 (enExample)

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US12220431B2 (en) 2018-02-07 2025-02-11 L.E.A.F. Holdings Group Llc Gamma polyglutamated antifolates and uses thereof
EP3749319A4 (en) 2018-02-07 2022-06-22 L.E.A.F Holdings Group LLC TETRAHYDROFOLATES ALPHA POLYGLUTAMATE AND THEIR USES
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JP7462950B2 (ja) 2018-02-14 2024-04-08 エル.イー.エー.エフ. ホールディングス グループ エルエルシー ガンマポリグルタミン酸化メトトレキセートおよびその使用
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US12310966B2 (en) 2018-02-07 2025-05-27 L.E.A.F. Holdings Group Llc Alpha polyglutamated aminopterin and uses thereof
EP3749314A4 (en) 2018-02-07 2022-02-23 L.E.A.F Holdings Group LLC ALPHA-POLYGLUTAMATE METHOTREXATE AND ITS USES
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CA3090753A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated pralatrexate and uses thereof
US12350271B2 (en) 2018-02-14 2025-07-08 L.E.A.F. Holdings Group Llc Gamma polyglutamated aminopterin and uses thereof
WO2019160735A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated tetrahydrofolates and uses thereof
US20230000997A1 (en) 2019-08-06 2023-01-05 L.E.A.F. Holdings Group Llc Processes of preparing polyglutamated antifolates and uses of their compositions

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