JP2021513550A5 - - Google Patents

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Publication number
JP2021513550A5
JP2021513550A5 JP2020543517A JP2020543517A JP2021513550A5 JP 2021513550 A5 JP2021513550 A5 JP 2021513550A5 JP 2020543517 A JP2020543517 A JP 2020543517A JP 2020543517 A JP2020543517 A JP 2020543517A JP 2021513550 A5 JP2021513550 A5 JP 2021513550A5
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JP
Japan
Prior art keywords
oxidized
tetrahydrofolate
liposome
optionally
polyglutamate
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JP2020543517A
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English (en)
Japanese (ja)
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JP2021513550A (ja
JP7442822B2 (ja
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Priority claimed from PCT/US2019/016966 external-priority patent/WO2019160735A1/en
Publication of JP2021513550A publication Critical patent/JP2021513550A/ja
Publication of JP2021513550A5 publication Critical patent/JP2021513550A5/ja
Priority to JP2024020715A priority Critical patent/JP7676056B2/ja
Application granted granted Critical
Publication of JP7442822B2 publication Critical patent/JP7442822B2/ja
Priority to JP2025070591A priority patent/JP2025111607A/ja
Active legal-status Critical Current
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JP2020543517A 2018-02-14 2019-02-07 γポリグルタミン酸化テトラヒドロ葉酸およびその使用 Active JP7442822B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024020715A JP7676056B2 (ja) 2018-02-14 2024-02-14 γポリグルタミン酸化テトラヒドロ葉酸およびその使用
JP2025070591A JP2025111607A (ja) 2018-02-14 2025-04-22 γポリグルタミン酸化テトラヒドロ葉酸およびその使用

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201862630824P 2018-02-14 2018-02-14
US62/630,824 2018-02-14
US201862636289P 2018-02-28 2018-02-28
US62/636,289 2018-02-28
US201862662372P 2018-04-25 2018-04-25
US62/662,372 2018-04-25
US201862702774P 2018-07-24 2018-07-24
US62/702,774 2018-07-24
US201862764945P 2018-08-17 2018-08-17
US62/764,945 2018-08-17
PCT/US2019/016966 WO2019160735A1 (en) 2018-02-14 2019-02-07 Gamma polyglutamated tetrahydrofolates and uses thereof

Related Child Applications (1)

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JP2024020715A Division JP7676056B2 (ja) 2018-02-14 2024-02-14 γポリグルタミン酸化テトラヒドロ葉酸およびその使用

Publications (3)

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JP2021513550A JP2021513550A (ja) 2021-05-27
JP2021513550A5 true JP2021513550A5 (enExample) 2022-03-03
JP7442822B2 JP7442822B2 (ja) 2024-03-05

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JP2020543517A Active JP7442822B2 (ja) 2018-02-14 2019-02-07 γポリグルタミン酸化テトラヒドロ葉酸およびその使用
JP2024020715A Active JP7676056B2 (ja) 2018-02-14 2024-02-14 γポリグルタミン酸化テトラヒドロ葉酸およびその使用
JP2025070591A Pending JP2025111607A (ja) 2018-02-14 2025-04-22 γポリグルタミン酸化テトラヒドロ葉酸およびその使用

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JP2024020715A Active JP7676056B2 (ja) 2018-02-14 2024-02-14 γポリグルタミン酸化テトラヒドロ葉酸およびその使用
JP2025070591A Pending JP2025111607A (ja) 2018-02-14 2025-04-22 γポリグルタミン酸化テトラヒドロ葉酸およびその使用

Country Status (6)

Country Link
US (1) US12048766B2 (enExample)
EP (1) EP3755335A4 (enExample)
JP (3) JP7442822B2 (enExample)
CN (1) CN111971047A (enExample)
CA (1) CA3090992A1 (enExample)
WO (1) WO2019160735A1 (enExample)

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US12220431B2 (en) 2018-02-07 2025-02-11 L.E.A.F. Holdings Group Llc Gamma polyglutamated antifolates and uses thereof
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EP3749318A4 (en) 2018-02-07 2022-07-06 L.E.A.F Holdings Group LLC GAMMA-POLYGLUTAMATED RALTITREXED AND ITS USES
WO2019157121A1 (en) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Alpha polyglutamated lometrexol and uses thereof
WO2019160735A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated tetrahydrofolates and uses thereof
JP7462950B2 (ja) 2018-02-14 2024-04-08 エル.イー.エー.エフ. ホールディングス グループ エルエルシー ガンマポリグルタミン酸化メトトレキセートおよびその使用
CA3090753A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated pralatrexate and uses thereof
US12350271B2 (en) 2018-02-14 2025-07-08 L.E.A.F. Holdings Group Llc Gamma polyglutamated aminopterin and uses thereof
WO2019160734A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated lometrexol and uses thereof

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US12350271B2 (en) 2018-02-14 2025-07-08 L.E.A.F. Holdings Group Llc Gamma polyglutamated aminopterin and uses thereof
CA3090753A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated pralatrexate and uses thereof
JP7462950B2 (ja) 2018-02-14 2024-04-08 エル.イー.エー.エフ. ホールディングス グループ エルエルシー ガンマポリグルタミン酸化メトトレキセートおよびその使用
WO2019160734A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated lometrexol and uses thereof
WO2019160735A1 (en) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Gamma polyglutamated tetrahydrofolates and uses thereof
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