JP2021510516A5 - - Google Patents
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- JP2021510516A5 JP2021510516A5 JP2020538794A JP2020538794A JP2021510516A5 JP 2021510516 A5 JP2021510516 A5 JP 2021510516A5 JP 2020538794 A JP2020538794 A JP 2020538794A JP 2020538794 A JP2020538794 A JP 2020538794A JP 2021510516 A5 JP2021510516 A5 JP 2021510516A5
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- 239000012530 fluid Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 6
- 239000000523 sample Substances 0.000 claims 5
- 239000012488 sample solution Substances 0.000 claims 5
- 239000007853 buffer solution Substances 0.000 claims 4
- 238000006467 substitution reaction Methods 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
- 238000002032 lab-on-a-chip Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/875,905 | 2018-01-19 | ||
| US15/875,905 US10946380B2 (en) | 2018-01-19 | 2018-01-19 | Microfluidic chips for particle purification and fractionation |
| PCT/IB2019/050272 WO2019142087A1 (en) | 2018-01-19 | 2019-01-14 | Microfluidic chips for particle purification and fractionation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021510516A JP2021510516A (ja) | 2021-04-30 |
| JP2021510516A5 true JP2021510516A5 (enExample) | 2021-06-17 |
Family
ID=67299122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538794A Pending JP2021510516A (ja) | 2018-01-19 | 2019-01-14 | 粒子の精製および分画のための方法およびマイクロ流体装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10946380B2 (enExample) |
| JP (1) | JP2021510516A (enExample) |
| CN (1) | CN111615552B (enExample) |
| DE (1) | DE112019000463B4 (enExample) |
| GB (1) | GB2583625A (enExample) |
| WO (1) | WO2019142087A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11458474B2 (en) | 2018-01-19 | 2022-10-04 | International Business Machines Corporation | Microfluidic chips with one or more vias |
| US20190226953A1 (en) | 2018-01-19 | 2019-07-25 | International Business Machines Corporation | Microscale and mesoscale condenser devices |
| US10946380B2 (en) | 2018-01-19 | 2021-03-16 | International Business Machines Corporation | Microfluidic chips for particle purification and fractionation |
| US20200316230A1 (en) * | 2019-04-08 | 2020-10-08 | Vanderbilt University | Devices and methods for radiopharmaceutical synthesis |
| US11266989B2 (en) * | 2019-08-07 | 2022-03-08 | International Business Machines Corporation | Immunodetection and separation on nanoDLD |
| US11517873B2 (en) | 2019-10-29 | 2022-12-06 | International Business Machines Corporation | Controlled chemical synthesis using polymer substrates and nanofluidic separation systems |
| US11565262B2 (en) * | 2020-03-10 | 2023-01-31 | International Business Machines Corporation | Continous band-pass filter size separation using a negative angle DLD array |
| CN111821601A (zh) * | 2020-05-27 | 2020-10-27 | 深圳艾素科技有限公司 | 一种电子过滤装置及其操作方法 |
| CN111778138B (zh) * | 2020-07-06 | 2022-01-11 | 中南大学 | 一种分选血浆中外泌体的微流控器件及其使用方法 |
| CN113652333B (zh) * | 2021-08-03 | 2023-03-21 | 中国科学院上海微系统与信息技术研究所 | 一种优化流体分布的微柱式多相位移通道 |
| CN114574357B (zh) * | 2022-02-14 | 2025-11-11 | 大连交通大学 | 一种基于确定性侧向位移和介电泳技术联用的微藻与细菌分选装置 |
| TWI889038B (zh) * | 2023-04-14 | 2025-07-01 | 前瞻優勢生醫股份有限公司 | 微流體微粒分選器 |
| CN117504956B (zh) * | 2023-10-16 | 2024-12-17 | 北京大学 | 一种微纳流控芯片及生化标志物分子的分离方法 |
| WO2025212802A1 (en) * | 2024-04-02 | 2025-10-09 | The General Hospital Corporation | Molecular analysis of cytology specimens |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2726018B2 (ja) | 1995-07-07 | 1998-03-11 | 株式会社サクション瓦斯機関製作所 | 多管式熱交換器 |
| US7892681B2 (en) | 2005-07-19 | 2011-02-22 | Pelton Walter E | System of distributed electrochemical cells integrated with microelectronic structures |
| ES2341103T3 (es) | 2002-10-23 | 2010-06-15 | The Trustees Of Princeton University | Procedimiento de separacion continua de particulas usando reticulados de obstaculos alineados asimetricamente respecto a campos. |
| WO2005100401A2 (en) * | 2004-03-31 | 2005-10-27 | Adnagen Ag | Monoclonal antibodies with specificity for fetal erythroid cells |
| US7281387B2 (en) | 2004-04-29 | 2007-10-16 | Carrier Commercial Refrigeration Inc. | Foul-resistant condenser using microchannel tubing |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| JP2008538282A (ja) * | 2005-04-05 | 2008-10-23 | セルポイント ダイアグノスティクス， インコーポレイテッド | 装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法 |
| WO2006124597A2 (en) | 2005-05-12 | 2006-11-23 | Foster Ron B | Infinitely stackable interconnect device and method |
| US7863189B2 (en) | 2007-01-05 | 2011-01-04 | International Business Machines Corporation | Methods for fabricating silicon carriers with conductive through-vias with low stress and low defect density |
| FR2931141B1 (fr) | 2008-05-13 | 2011-07-01 | Commissariat Energie Atomique | Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri |
| EP2304414B1 (en) | 2008-07-24 | 2017-03-15 | The Trustees of Princeton University | Bump array device having asymmetric gaps for segregation of particles |
| US8093099B2 (en) | 2008-09-26 | 2012-01-10 | International Business Machines Corporation | Lock and key through-via method for wafer level 3D integration and structures produced |
| WO2010124155A1 (en) | 2009-04-23 | 2010-10-28 | Logos Energy, Inc. | Lateral displacement array for microfiltration |
| US9039996B2 (en) | 2010-10-12 | 2015-05-26 | Stmicroelectronics, Inc. | Silicon substrate optimization for microarray technology |
| CN102052803B (zh) | 2010-12-13 | 2012-11-28 | 上海环球制冷设备有限公司 | 集成冷凝满液式蒸发器装置及使用方法 |
| WO2012094642A2 (en) | 2011-01-06 | 2012-07-12 | On-Q-ity | Circulating tumor cell capture on a microfluidic chip incorporating both affinity and size |
| US20170271207A9 (en) | 2011-01-29 | 2017-09-21 | International Business Machines Corporation | Novel 3D Integration Method Using SOI Substrates And Structures Produced Thereby |
| CN102856329B (zh) | 2011-06-30 | 2015-02-11 | 中芯国际集成电路制造(上海)有限公司 | 一种硅通孔封装方法 |
| CN108212237B (zh) * | 2013-03-06 | 2020-12-08 | 哈佛学院院长及董事 | 形成相对单分散液滴的装置和方法 |
| CN105247042B (zh) * | 2013-03-15 | 2021-06-11 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| CN110186835B (zh) | 2013-03-15 | 2022-05-31 | Gpb科学有限公司 | 颗粒的片上微流体处理 |
| WO2014166000A1 (en) * | 2013-04-11 | 2014-10-16 | The Governing Council Of The University Of Toronto | Device for capture of particles in a flow |
| US10202577B2 (en) | 2013-10-18 | 2019-02-12 | The General Hospital Corporation | Microfluidic sorting using high gradient magnetic fields |
| JP6604945B2 (ja) | 2013-11-22 | 2019-11-13 | ザ ジェネラル ホスピタル コーポレイション | 粒子クラスタを単離するためのマイクロ流体方法およびシステム |
| CA2966623C (en) | 2014-11-03 | 2024-02-20 | The General Hospital Corporation | Concentrating particles in a microfluidic device |
| US9636675B2 (en) | 2014-11-26 | 2017-05-02 | International Business Machines Corporation | Pillar array structure with uniform and high aspect ratio nanometer gaps |
| US9835538B2 (en) | 2014-11-26 | 2017-12-05 | International Business Machines Corporation | Biopolymer separation using nanostructured arrays |
| US10058895B2 (en) | 2014-11-26 | 2018-08-28 | International Business Machines Corporation | Continuous flow, size-based separation of entities down to the nanometer scale using nanopillar arrays |
| CN105161473A (zh) | 2015-07-09 | 2015-12-16 | 江苏中圣压力容器装备制造有限公司 | 硅基毛细泵回路微型冷却器 |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| CN105293428B (zh) | 2015-10-19 | 2017-04-19 | 北京航天控制仪器研究所 | 一种mems器件的全硅化圆片级真空封装方法及封装器件 |
| US9700891B2 (en) | 2015-11-13 | 2017-07-11 | International Business Machines Corporation | Integrated nanofluidic arrays for high capacity colloid separation |
| WO2017087940A1 (en) | 2015-11-20 | 2017-05-26 | University Of Kansas | Non-invasive monitoring cancer using integrated microfluidic profiling of circulating microvesicles |
| US10507466B2 (en) | 2016-04-27 | 2019-12-17 | International Business Machines Corporation | Metal assisted chemical etching for fabricating high aspect ratio and straight silicon nanopillar arrays for sorting applications |
| CN109328098A (zh) | 2016-06-20 | 2019-02-12 | 凸版印刷株式会社 | 液体介质的置换方法及用于该方法的流路设备 |
| US10386276B2 (en) | 2016-09-20 | 2019-08-20 | International Business Machines Corporation | Phosphoprotein detection using a chip-based pillar array |
| US10010883B2 (en) * | 2016-09-20 | 2018-07-03 | International Business Machines Corporation | Deterministic lateral displacement arrays |
| US10253350B2 (en) | 2016-09-20 | 2019-04-09 | International Business Machines Corporation | Separation of molecules using nanopillar arrays |
| US20200038861A1 (en) * | 2016-10-07 | 2020-02-06 | The Regents Of The University Of Michigan | Systems and methods for high throughput screening |
| US20190226953A1 (en) | 2018-01-19 | 2019-07-25 | International Business Machines Corporation | Microscale and mesoscale condenser devices |
| US10946380B2 (en) | 2018-01-19 | 2021-03-16 | International Business Machines Corporation | Microfluidic chips for particle purification and fractionation |
| US11149298B2 (en) | 2018-06-13 | 2021-10-19 | International Business Machines Corporation | Detection of nucleic acid sequences using deterministic lateral displacement arrays |
| US11033901B2 (en) | 2018-10-23 | 2021-06-15 | International Business Machines Corporation | Biomarker detection using integrated purification-detection devices |
-
2018
- 2018-01-19 US US15/875,905 patent/US10946380B2/en active Active
-
2019
- 2019-01-14 JP JP2020538794A patent/JP2021510516A/ja active Pending
- 2019-01-14 GB GB2010486.5A patent/GB2583625A/en not_active Withdrawn
- 2019-01-14 DE DE112019000463.8T patent/DE112019000463B4/de active Active
- 2019-01-14 CN CN201980008710.XA patent/CN111615552B/zh active Active
- 2019-01-14 WO PCT/IB2019/050272 patent/WO2019142087A1/en not_active Ceased
-
2020
- 2020-12-23 US US17/132,849 patent/US11872560B2/en active Active
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