FR2931141B1 - Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri - Google Patents
Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur triInfo
- Publication number
- FR2931141B1 FR2931141B1 FR0802575A FR0802575A FR2931141B1 FR 2931141 B1 FR2931141 B1 FR 2931141B1 FR 0802575 A FR0802575 A FR 0802575A FR 0802575 A FR0802575 A FR 0802575A FR 2931141 B1 FR2931141 B1 FR 2931141B1
- Authority
- FR
- France
- Prior art keywords
- sorting
- amas
- preference
- cells
- microfluidic system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
- B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
- B01F23/414—Emulsifying characterised by the internal structure of the emulsion
- B01F23/4145—Emulsions of oils, e.g. fuel, and water
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
- Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2525—Stabilizing or preserving
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0802575A FR2931141B1 (fr) | 2008-05-13 | 2008-05-13 | Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri |
EP09290311.1A EP2119503B1 (fr) | 2008-05-13 | 2009-04-29 | Système microfluidique et procédé pour le tri d'amas de cellules et pour leur encapsulation en continu suite à leur tri |
JP2009112687A JP5414347B2 (ja) | 2008-05-13 | 2009-05-07 | 細胞集団を選別するため、および選別後の細胞集団を連続的にカプセル化するためのマイクロ流体システムおよび方法 |
US12/437,901 US8263023B2 (en) | 2008-05-13 | 2009-05-08 | Microfluidic system and method for sorting cell clusters and for the continuous encapsulation thereof following sorting thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0802575A FR2931141B1 (fr) | 2008-05-13 | 2008-05-13 | Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2931141A1 FR2931141A1 (fr) | 2009-11-20 |
FR2931141B1 true FR2931141B1 (fr) | 2011-07-01 |
Family
ID=40134794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0802575A Active FR2931141B1 (fr) | 2008-05-13 | 2008-05-13 | Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri |
Country Status (4)
Country | Link |
---|---|
US (1) | US8263023B2 (fr) |
EP (1) | EP2119503B1 (fr) |
JP (1) | JP5414347B2 (fr) |
FR (1) | FR2931141B1 (fr) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9574832B2 (en) * | 2007-12-28 | 2017-02-21 | Intel Corporation | Enabling an aluminum heat exchanger with a working fluid |
FR2946895A1 (fr) * | 2009-06-19 | 2010-12-24 | Commissariat Energie Atomique | Systeme microfluidique et procede correspondant pour le transfert d'elements entre phases liquides et utilisation de ce systeme pour extraire ces elements |
CN102714649B (zh) | 2009-12-01 | 2015-02-18 | 日本电气株式会社 | 数据传输方法、数据接收方法、数据调制设备、数据解调设备 |
ITTO20100068U1 (it) * | 2010-04-20 | 2011-10-21 | Eltek Spa | Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici |
EP2594332B1 (fr) * | 2010-07-13 | 2020-03-04 | Tokyo Institute of Technology | Appareil pour la production de microgouttelettes de liquide |
ES2669870T3 (es) * | 2010-07-22 | 2018-05-29 | Gencell Biosystems Limited | Células de líquido compuesto |
AU2011302302B2 (en) | 2010-09-14 | 2014-12-11 | The Regents Of The University Of California | Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices |
US9090865B2 (en) | 2010-10-29 | 2015-07-28 | The Regents Of The University Of California | Systems and methods for particle classification and sorting |
US8870733B2 (en) * | 2010-11-19 | 2014-10-28 | Kensey Nash Corporation | Centrifuge |
CN102095284B (zh) * | 2011-01-30 | 2013-03-27 | 杭州沈氏换热器有限公司 | 一种换热器的微通道换热体的制造方法 |
US20120214224A1 (en) * | 2011-02-01 | 2012-08-23 | Chan Eugene Y | Flow based clinical analysis |
US20120202284A1 (en) * | 2011-02-07 | 2012-08-09 | Empire Technology Development Llc | Cell sorting apparatus and method |
US20120208255A1 (en) * | 2011-02-14 | 2012-08-16 | Geosynfuels, Llc | Apparatus and process for production of an encapsulated cell product |
CN102530833B (zh) * | 2011-12-02 | 2014-10-29 | 江苏大学 | 一种封闭式微流控通道刻蚀方法与自动刻蚀装置 |
WO2013116696A1 (fr) * | 2012-02-03 | 2013-08-08 | University Of Cincinnati | Procédés microfluidiques pour la séparation passive de cellules et de particules |
WO2013177560A1 (fr) | 2012-05-25 | 2013-11-28 | The Regents Of The University Of California | Systèmes microfluidiques pour piégeage et séparation de particules |
US9222874B2 (en) * | 2012-06-27 | 2015-12-29 | The United States Of America As Represented By The Secretary Of The Army | Systems and methods for individually trapping particles from air and measuring the optical spectra or other properties of individual trapped particles |
WO2014062719A2 (fr) | 2012-10-15 | 2014-04-24 | Nanocellect Biomedical, Inc. | Systèmes, appareil et procédés de tri de particules |
CN104812492A (zh) | 2012-11-27 | 2015-07-29 | 基因细胞生物系统有限公司 | 处理液体样品 |
CN113512522A (zh) | 2013-03-15 | 2021-10-19 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
WO2014145152A2 (fr) | 2013-03-15 | 2014-09-18 | Gpb Scientific, Llc | Traitement microfluidique intégré de particules |
US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
WO2014145237A1 (fr) * | 2013-03-15 | 2014-09-18 | Dialyflux, Llc | Surfaces permettant de manipuler un flux de particules |
CN106029885A (zh) | 2014-02-10 | 2016-10-12 | 基因细胞生物系统有限公司 | 复合液体池(clc)介导的核酸文库制备装置及其使用方法 |
WO2015200857A1 (fr) | 2014-06-27 | 2015-12-30 | The Regents Of The University Of California | Appareil et procédé pour analyse sans marqueur de cellules rares provenant de fluides corporels |
EP3209766A4 (fr) | 2014-10-20 | 2018-08-15 | University of Utah Research Foundation | Système de traitement d'échantillons tissulaires et procédés associés |
WO2016205742A1 (fr) * | 2015-06-17 | 2016-12-22 | The Regents Of The University Of California | Dispositif microfluidique à haut rendement pour le piégeage de cellules tumorales circulantes |
US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
US9862941B2 (en) | 2015-10-14 | 2018-01-09 | Pioneer Hi-Bred International, Inc. | Single cell microfluidic device |
KR101758826B1 (ko) * | 2015-11-27 | 2017-07-18 | 한국과학기술연구원 | 용액의 이온농도 조절을 이용한 미세유체칩 여과 방법 및 장치 |
KR101807256B1 (ko) * | 2016-01-26 | 2017-12-08 | 한양대학교 에리카산학협력단 | 입자 분리 장치 및 입자 분리 방법 |
CA3016871A1 (fr) * | 2016-03-07 | 2017-09-14 | Hitachi Chemical Advanced Therapeutics Solutions, LLC | Systeme ferme pour le marquage et la selection de cellules vivantes |
WO2017184854A1 (fr) * | 2016-04-20 | 2017-10-26 | Nathan Swami | Systèmes et procédés d'isolation et de transplantation d'îlots pancréatiques |
US10717086B2 (en) | 2016-08-29 | 2020-07-21 | The Regents Of The University Of California | Integrated system for isolation and emulsification of particles and cells |
US10010883B2 (en) | 2016-09-20 | 2018-07-03 | International Business Machines Corporation | Deterministic lateral displacement arrays |
US11090653B2 (en) | 2016-10-11 | 2021-08-17 | The Regents Of The University Of California | Systems and methods to encapsulate and preserve organic matter for analysis |
FR3058328B1 (fr) * | 2016-11-07 | 2019-01-25 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Equipement de tri de particules presentes dans un echantillon fluidique |
US10471425B2 (en) | 2017-02-16 | 2019-11-12 | International Business Machines Corporation | Automated machine for sorting of biological fluids |
US10780438B2 (en) | 2017-06-09 | 2020-09-22 | The Regents Of The University Of California | High-efficiency encapsulation in droplets based on hydrodynamic vortices control |
US11517901B2 (en) | 2017-06-09 | 2022-12-06 | The Regents Of The University Of California | High-efficiency particle encapsulation in droplets with particle spacing and downstream droplet sorting |
EP3677337A4 (fr) * | 2017-08-30 | 2021-05-26 | Kyocera Corporation | Dispositif de séparation de particules et procédé de production de particules l'utilisant |
US10844353B2 (en) | 2017-09-01 | 2020-11-24 | Gpb Scientific, Inc. | Methods for preparing therapeutically active cells using microfluidics |
WO2019075409A1 (fr) * | 2017-10-12 | 2019-04-18 | The Regents Of The University Of California | Isolement et identification sans étiquette microfluidique de cellules à l'aide d'une imagerie de durée de vie de fluorescence (flim) |
WO2019079787A1 (fr) | 2017-10-20 | 2019-04-25 | The Regents Of The University Of California | Systèmes microfluidiques et procédés pour la transfection cellulaire via des lipoflex |
US11499127B2 (en) | 2017-10-20 | 2022-11-15 | The Regents Of The University Of California | Multi-layered microfluidic systems for in vitro large-scale perfused capillary networks |
US20190210016A1 (en) * | 2018-01-05 | 2019-07-11 | Genturi, Inc. | Duty cycle optimization in single-molecule detection |
US11458474B2 (en) | 2018-01-19 | 2022-10-04 | International Business Machines Corporation | Microfluidic chips with one or more vias |
US20190226953A1 (en) | 2018-01-19 | 2019-07-25 | International Business Machines Corporation | Microscale and mesoscale condenser devices |
US10946380B2 (en) | 2018-01-19 | 2021-03-16 | International Business Machines Corporation | Microfluidic chips for particle purification and fractionation |
JP2019152477A (ja) * | 2018-03-01 | 2019-09-12 | 株式会社エンプラス | 液体取扱装置 |
US11673107B2 (en) | 2018-05-01 | 2023-06-13 | Hewlett-Packard Development Company, L.P. | Sequential encapsulation of reagents |
US10697719B2 (en) | 2018-08-09 | 2020-06-30 | International Business Machines Corporation | Monitoring a recirculating cooling system for bacterial growth |
WO2020066306A1 (fr) * | 2018-09-28 | 2020-04-02 | 富士フイルム株式会社 | Structure cellulaire, procédé de production de structure cellulaire, procédé de culture cellulaire et voie de micro-écoulement |
WO2020072303A1 (fr) * | 2018-10-03 | 2020-04-09 | Verily Life Sciences Llc | Systèmes et procédés pour maintenir des débits volumétriques constants dans un canal de fluide |
US20210394183A1 (en) * | 2018-11-14 | 2021-12-23 | Sindy Kam Yan TANG | Microfluidic device and diagnostic methods for allergy testing based on detection of basophil activation |
BE1026910B1 (nl) * | 2018-12-21 | 2020-07-22 | Pharmafluidics N V | Chemische reactoren |
CN109943475A (zh) * | 2019-04-12 | 2019-06-28 | 广西医科大学第一附属医院 | 一种微流控分选芯片及其分选系统 |
CN114126762B (zh) * | 2019-04-30 | 2023-01-03 | 伯克利之光生命科技公司 | 用于包封和测定细胞的方法 |
CN114207407A (zh) * | 2019-05-31 | 2022-03-18 | 安伯斯顿生物科学股份有限公司 | 低丰度事件的微流体确定 |
FR3117884B1 (fr) | 2020-12-21 | 2024-02-16 | Commissariat Energie Atomique | Système de tri par taille de particules expulsées par centrifugation et procédé de configuration d'un tel système |
CN114100706B (zh) * | 2021-10-18 | 2022-08-19 | 吉林大学 | 一种基于粒子漂移的粒子分选方法及系统 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5770029A (en) * | 1996-07-30 | 1998-06-23 | Soane Biosciences | Integrated electrophoretic microdevices |
AU720662B2 (en) * | 1995-04-07 | 2000-06-08 | Albert Einstein College Of Medicine Of Yeshiva University | Recombinant B-cell and uses thereof |
US6540895B1 (en) * | 1997-09-23 | 2003-04-01 | California Institute Of Technology | Microfabricated cell sorter for chemical and biological materials |
JP3081880B2 (ja) | 1998-03-30 | 2000-08-28 | 農林水産省食品総合研究所長 | マイクロスフィアの連続製造装置 |
US6132685A (en) * | 1998-08-10 | 2000-10-17 | Caliper Technologies Corporation | High throughput microfluidic systems and methods |
AU2001290879A1 (en) | 2000-09-15 | 2002-03-26 | California Institute Of Technology | Microfabricated crossflow devices and methods |
AU2002230524A1 (en) | 2000-11-16 | 2002-05-27 | California Institute Of Technology | Apparatus and methods for conducting assays and high throughput screening |
WO2002044689A2 (fr) * | 2000-11-28 | 2002-06-06 | The Regents Of The University Of California | Commutation et tri optiques d'echantillons et microparticules biologiques transportes dans un dispositif microfluidique, notamment des puces biologiques incorporees |
JP4182195B2 (ja) | 2001-09-03 | 2008-11-19 | 独立行政法人農業・食品産業技術総合研究機構 | 単分散複合型エマルションの製造装置 |
EP1499706A4 (fr) * | 2002-04-01 | 2010-11-03 | Fluidigm Corp | Systemes d'analyse de particules microfluidiques |
US7452507B2 (en) * | 2002-08-02 | 2008-11-18 | Sandia Corporation | Portable apparatus for separating sample and detecting target analytes |
JPWO2004026457A1 (ja) | 2002-09-18 | 2006-06-15 | 中嶋 光敏 | マイクロカプセルの製造方法 |
ATE463292T1 (de) | 2002-10-23 | 2010-04-15 | Univ Princeton | Verfahren zur kontinuierlichen teilchentrennung unter verwendungvon zu feldern asymmetrisch ausgerichteten hindernisarrays |
JP2004154747A (ja) * | 2002-11-02 | 2004-06-03 | Minoru Seki | 連続粒子分離機構及びその装置 |
WO2004071638A2 (fr) | 2003-02-11 | 2004-08-26 | Regents Of The University Of California, The | Dispositifs microfluidiques pour cisaillement visqueux commande et formation de vesicules amphiphiles |
US20060078893A1 (en) * | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
EP1533605A3 (fr) * | 2003-11-19 | 2006-05-31 | Aisin Seiki Kabushiki Kaisha | Microsystème de commande pour le transfert de liquide |
US20050133480A1 (en) | 2003-12-19 | 2005-06-23 | Xerox Corporation | Methods for making internal die filters with multiple passageways which are fluidically in parallel |
EP1742979A4 (fr) | 2004-04-23 | 2008-05-21 | Eugenia Kumacheva | Procede de production de particules polymeres ayant une taille, une forme, une morphologie et une composition selectionnees |
US7759111B2 (en) | 2004-08-27 | 2010-07-20 | The Regents Of The University Of California | Cell encapsulation microfluidic device |
US20070009668A1 (en) | 2004-11-18 | 2007-01-11 | Wyman Jason L | Microencapsulation of particles in a polymer solution by selective withdrawal through a high viscosity low density fluid and subsequent crosslinking |
WO2006078841A1 (fr) | 2005-01-21 | 2006-07-27 | President And Fellows Of Harvard College | Systemes et procedes de formation de gouttelettes fluidiques encapsulees dans des particules telles que des particules colloidales |
WO2006079007A2 (fr) | 2005-01-21 | 2006-07-27 | President And Fellows Of Harvard College | Microconcentrateur/microfiltre |
US20070054119A1 (en) | 2005-03-04 | 2007-03-08 | Piotr Garstecki | Systems and methods of forming particles |
US7851189B2 (en) * | 2005-03-07 | 2010-12-14 | Boston Scientific Scimed, Inc. | Microencapsulated compositions for endoluminal tissue engineering |
US7775370B2 (en) | 2005-03-21 | 2010-08-17 | Utah State University | Particle sorting by fluidic vectoring |
JP2006263693A (ja) | 2005-03-22 | 2006-10-05 | Minoru Seki | 微粒子の連続分離機構及び装置 |
US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
GB0508983D0 (en) * | 2005-05-03 | 2005-06-08 | Oxford Gene Tech Ip Ltd | Cell analyser |
US7998328B2 (en) * | 2005-06-27 | 2011-08-16 | Cfd Research Corporation | Method and apparatus for separating particles by dielectrophoresis |
JP2007021465A (ja) | 2005-07-12 | 2007-02-01 | Minoru Seki | 粒子を連続的に濃縮・分離するための流路構造および方法 |
US20070059781A1 (en) | 2005-09-15 | 2007-03-15 | Ravi Kapur | System for size based separation and analysis |
JP2009509143A (ja) * | 2005-09-15 | 2009-03-05 | アルテミス ヘルス,インク. | 分析改善システムおよび方法 |
US7964078B2 (en) * | 2005-11-07 | 2011-06-21 | The Regents Of The University Of California | Microfluidic device for cell and particle separation |
WO2007114794A1 (fr) * | 2006-03-31 | 2007-10-11 | Nam Trung Nguyen | regulation active pour reseau microfluidique a gouttelettes |
-
2008
- 2008-05-13 FR FR0802575A patent/FR2931141B1/fr active Active
-
2009
- 2009-04-29 EP EP09290311.1A patent/EP2119503B1/fr active Active
- 2009-05-07 JP JP2009112687A patent/JP5414347B2/ja active Active
- 2009-05-08 US US12/437,901 patent/US8263023B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2119503A3 (fr) | 2012-02-22 |
FR2931141A1 (fr) | 2009-11-20 |
EP2119503A2 (fr) | 2009-11-18 |
US20090286300A1 (en) | 2009-11-19 |
JP5414347B2 (ja) | 2014-02-12 |
US8263023B2 (en) | 2012-09-11 |
JP2009273461A (ja) | 2009-11-26 |
EP2119503B1 (fr) | 2015-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2931141B1 (fr) | Systeme microfluidique et procede pour le tri d'amas de cellules et de preference pour leur encapsulation en continu suite a leur tri | |
GB2449560B (en) | Method and apparatus for real-time polars | |
HK1157262A1 (en) | System and method for plasma reduced platelet collection | |
EP2260646A4 (fr) | Procédé et systèmes pour la collecte de vidéos et analyse associée | |
PL2190950T3 (pl) | Sposób i urządzenie do wytwarzania ciekłego biopaliwa ze stałej biomasy | |
EP2040843A4 (fr) | Appareil et procédé pour une séparation continue de particules | |
FR2931006B1 (fr) | Systeme et procede pour la reconnaissance visuelle | |
FR2934911B1 (fr) | Systeme automatise de guidage et de reconnaissance et procede pour ledit systeme | |
EP2213712A4 (fr) | Procédé de séparation de triglycéride 1,3-disaturé-2-insaturé | |
EP2109526A4 (fr) | Appareil, système et procédé de soudage par friction à mouvement continu | |
EP2169070A4 (fr) | Procédé d'introduction d'une substance étrangère dans une cellule ayant une paroi cellulaire | |
GB2462234B (en) | Process for the separation of diastereomers | |
EP2214751A4 (fr) | Procédé et dispositif pour une différenciation de substances | |
IL205150A0 (en) | Method and system for controlled rate freezing of biological material | |
EP2352533A4 (fr) | Système et procédé pour séparer des cellules de liquides biologiques | |
FR2923494B1 (fr) | Membranes imper-respirantes et leur procede de fabrication | |
EP2190974A4 (fr) | Appareil et procédé pour déshydrater des matières biologiques | |
FR2937449B1 (fr) | Procede et systeme d'enrichissement de mel | |
IL209008A0 (en) | System and method for ip target traffic analysis | |
EP2181428A4 (fr) | Procédé et système d'analyse et d'optimisation de produits et services | |
EP2577520A4 (fr) | Procédé et appareil destinés à générer des bouts de code basés sur des cartes | |
PL2229784T3 (pl) | Sposób i urządzenie do wytwarzania w czasie rzeczywistym obrazów typu multiview | |
FR2904326B1 (fr) | Compositions de lubrifiants, procede pour leur preparation, et leur utilisation | |
FR2967972B1 (fr) | Procede de commande d'un systeme de flottabilite pour aeronef et systeme de flottabilite mettant en oeuvre ledit procede, et aeronef | |
FR2924553B1 (fr) | Procede pour ameliorer l'integrite de moyens de communication |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 8 |
|
PLFP | Fee payment |
Year of fee payment: 9 |
|
PLFP | Fee payment |
Year of fee payment: 10 |
|
PLFP | Fee payment |
Year of fee payment: 11 |
|
PLFP | Fee payment |
Year of fee payment: 12 |
|
PLFP | Fee payment |
Year of fee payment: 13 |
|
PLFP | Fee payment |
Year of fee payment: 14 |
|
PLFP | Fee payment |
Year of fee payment: 15 |
|
PLFP | Fee payment |
Year of fee payment: 16 |