JP2021502816A5 - - Google Patents

Download PDF

Info

Publication number
JP2021502816A5
JP2021502816A5 JP2020526478A JP2020526478A JP2021502816A5 JP 2021502816 A5 JP2021502816 A5 JP 2021502816A5 JP 2020526478 A JP2020526478 A JP 2020526478A JP 2020526478 A JP2020526478 A JP 2020526478A JP 2021502816 A5 JP2021502816 A5 JP 2021502816A5
Authority
JP
Japan
Prior art keywords
cells
cell population
antibody
engineered
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020526478A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021502816A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/061384 external-priority patent/WO2019099744A1/en
Publication of JP2021502816A publication Critical patent/JP2021502816A/ja
Publication of JP2021502816A5 publication Critical patent/JP2021502816A5/ja
Pending legal-status Critical Current

Links

JP2020526478A 2017-11-15 2018-11-15 δ3γδT細胞集団の選択的増殖方法及びその組成物 Pending JP2021502816A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762586782P 2017-11-15 2017-11-15
US62/586,782 2017-11-15
PCT/US2018/061384 WO2019099744A1 (en) 2017-11-15 2018-11-15 METHODS FOR SELECTIVE EXPANSION OF δ3 γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF

Publications (2)

Publication Number Publication Date
JP2021502816A JP2021502816A (ja) 2021-02-04
JP2021502816A5 true JP2021502816A5 (https=) 2021-12-23

Family

ID=64755702

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020526478A Pending JP2021502816A (ja) 2017-11-15 2018-11-15 δ3γδT細胞集団の選択的増殖方法及びその組成物

Country Status (12)

Country Link
US (1) US12221480B2 (https=)
EP (1) EP3710472A1 (https=)
JP (1) JP2021502816A (https=)
KR (1) KR20200098518A (https=)
CN (1) CN111801349A (https=)
AU (1) AU2018370120C1 (https=)
CA (1) CA3082818A1 (https=)
IL (1) IL274640B2 (https=)
MX (1) MX2020005005A (https=)
SG (1) SG11202004506WA (https=)
WO (1) WO2019099744A1 (https=)
ZA (1) ZA202003097B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020117862A1 (en) 2018-12-03 2020-06-11 Adicet Bio, Inc. Methods for selective in vivo expansion of gamma delta t-cell populations and compositions thereof
WO2020220016A1 (en) * 2019-04-26 2020-10-29 H. Lee Moffitt Cancer Center And Research Institute, Inc. Artificial antigen presenting cells comprising ligands for nkg2d for expanding immune cells for immunotherapy
JP2023504185A (ja) * 2019-12-03 2023-02-01 アディセット バイオ, インコーポレイテッド γδT細胞集団を多価薬剤で増殖させるための方法及びその組成物
JP2024539088A (ja) * 2021-10-20 2024-10-28 ユニバーシティ オブ ピッツバーグ -オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 腫瘍浸潤ガンマ-デルタt細胞を拡大するための方法及び材料

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260223A (en) 1986-07-03 1993-11-09 President & Fellows Of Harvard College Methods for detection of human gamma, γ T cell receptor
US5185250A (en) 1986-07-03 1993-02-09 T Cell Sciences, Inc. Human γ, δT cell antigen receptor polypeptides and nucleic acids
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
JPH07505773A (ja) 1992-04-03 1995-06-29 ヤング アレキサンダー ティー 標的化されたウイルスベクターを用いた遺伝子治療
CA2110946A1 (en) 1992-12-09 1994-06-10 Elazar Rabbani Induction of immunocompatibility by nucleic acid
AU783250B2 (en) 1999-06-17 2005-10-06 Dartmouth College Autologous adoptive immunotherapy with primed antigen-specific T cells or B cells
US6737398B1 (en) 1999-09-30 2004-05-18 National Jewish Medical And Research Center Modulation of γδ T cells to regulate airway hyperresponsiveness
WO2001022816A1 (en) 1999-09-30 2001-04-05 National Jewish Medical And Research Center MODULATION OF ηδ T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS
EP1476547B1 (en) 2002-01-23 2006-12-06 The University of Utah Research Foundation Targeted chromosomal mutagenesis using zinc finger nucleases
CN1306027C (zh) 2002-12-12 2007-03-21 中国医学科学院基础医学研究所 一种体外扩增γδT淋巴细胞的方法
US20060205089A1 (en) 2003-04-14 2006-09-14 Montana State University Mapping discontinuous antibody or aptamer epitopes for protein structure determination and other applications
US7985739B2 (en) 2003-06-04 2011-07-26 The Board Of Trustees Of The Leland Stanford Junior University Enhanced sleeping beauty transposon system and methods for using the same
JP5139800B2 (ja) 2004-06-03 2013-02-06 ノビミューン エスアー 抗cd3抗体およびその使用方法
US7340913B2 (en) 2004-08-05 2008-03-11 Manitowoc Foodservice Companies, Inc. Ice machine and ice-making assembly including a water distributor
US20080026986A1 (en) 2006-06-05 2008-01-31 Rong-Fu Wang Reversal of the suppressive function of specific t cells via toll-like receptor 8 signaling
CA2914170C (en) 2006-09-08 2018-10-30 Abbvie Bahamas Ltd. Interleukin-13 binding proteins
AU2009288354A1 (en) 2008-08-26 2010-03-11 Macrogenics Inc. T-cell receptor antibodies and methods of use thereof
KR101866578B1 (ko) 2010-01-22 2018-06-11 다우 아그로사이언시즈 엘엘씨 표적화된 게놈 교체
CA2993567C (en) 2010-07-21 2022-06-28 Sangamo Biosciences, Inc. Methods and compositions for modification of a t-cell receptor gene
KR20140033029A (ko) 2011-04-01 2014-03-17 메모리얼 슬로안-케터링 캔서 센터 에이치엘에이 에이2에 의해 제공된 더블유티1 펩타이드에 특이적인 티 세포 수용체 유사 항체
CN103635573B (zh) 2011-05-19 2016-05-11 分子医学研究所 包含γδT细胞的淋巴细胞系、其组合物及生产方法
WO2013074916A1 (en) 2011-11-18 2013-05-23 Board Of Regents, The University Of Texas System Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla
HRP20201595T1 (hr) 2011-11-28 2020-12-11 Merck Patent Gmbh Anti-pd-l1 protutijela i njihova uporaba
EP2684600A1 (en) 2012-07-10 2014-01-15 Laboratoires Meiners Sarl Core-shell capsules and methods for encapsulation of reactive ingredients by diffusional exchange through spherical capsule membranes
US20150259645A1 (en) 2012-11-08 2015-09-17 INSERM (Institut National de la Santé et de la Recherche Médicale Method for inducing il-2-free proliferation of gamma delta t cells
CN102994448A (zh) 2012-12-13 2013-03-27 上海柯莱逊生物技术有限公司 一种体外扩增γδT细胞的方法
WO2014134412A1 (en) 2013-03-01 2014-09-04 Regents Of The University Of Minnesota Talen-based gene correction
JP2016539929A (ja) 2013-10-25 2016-12-22 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 免疫療法のためのポリクローナルγδT細胞
EP3129404B1 (en) 2014-04-10 2026-01-28 LAVA Therapeutics N.V. Immunoglobulins binding human vgamma9vdelta2 t cell receptors
WO2016081518A2 (en) * 2014-11-17 2016-05-26 Adicet Bio, Inc. Engineered gamma delta t-cells
AU2016274633B2 (en) * 2015-06-09 2022-04-21 Gammadelta Therapeutics Ltd Methods for the production of TCR gamma delta+ T cells
EP3322801A1 (en) 2015-07-15 2018-05-23 Juno Therapeutics, Inc. Engineered cells for adoptive cell therapy
EP3454870A4 (en) 2016-05-12 2020-03-04 Adicet Bio Inc. METHOD FOR SELECTIVE EXPANSION OF GAMMA DELTA T CELL POPULATIONS AND COMPOSITIONS THEREOF

Similar Documents

Publication Publication Date Title
KR102618231B1 (ko) 변형된 만능성 줄기 세포, 및 제조 및 사용 방법
JP5184732B2 (ja) T細胞亜集団に特異的なモノクローナル抗体およびポリクローナル抗体の組成物および使用方法
JP2017535292A5 (https=)
TW202140530A (zh) 前列腺特異性膜抗原car及其使用方法
CN111566201A (zh) 使用用于表达嵌合抗原受体(car)或转基因t细胞受体(tcr)的病毒载体转导细胞的方法
EP4545639A2 (en) Engineered gamma delta t-cells
CN112912494A (zh) γ-δT细胞和自然杀伤细胞的治疗制剂以及制造和使用方法
US20200353004A1 (en) Regulatory T Cell Expressing a Chimeric Antigen Receptor
US20120315269A1 (en) Immunoglobulin-like transcript (ilt) receptors as cd8 antagonists
CN104884095A (zh) Cart19用于耗减正常b细胞以诱导耐受的用途
JP2021502816A5 (https=)
CN108138148A (zh) T细胞的激活和扩增
WO2019154313A1 (zh) 一种分离的嵌合抗原受体以及包含其的修饰t细胞及用途
KR20220144888A (ko) 최적화된 다기능 t 세포를 포함하는 키메라 수용체 t 세포를 사용하는 치료
US11697677B2 (en) Chimeric molecules providing targeted costimulation for adoptive cell therapy
US20240197873A1 (en) Modified tumor-infiltrating lymphocyte and use thereof
CN118891290A (zh) 细胞免疫疗法的组合物和方法
CN110819596A (zh) 具有增强的迁移能力的修饰的细胞
AU727955B2 (en) Cellular vaccines and immunotherapeutics and methods for their preparation
Lankester et al. Will post-transplantation cell therapies for pediatric patients become standard of care?
WO2024193714A1 (zh) 细胞免疫疗法的组合物和方法
WO2025214498A1 (en) Composition and method of cellular immunotherapy
EP4714981A1 (en) Immune effector cell and use thereof
WO2025213573A1 (zh) 细胞免疫疗法的组合物和方法
WO2024130179A1 (en) T cell receptors binding hpv-16 epitopes