JP2021501611A5 - - Google Patents

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Publication number
JP2021501611A5
JP2021501611A5 JP2020544351A JP2020544351A JP2021501611A5 JP 2021501611 A5 JP2021501611 A5 JP 2021501611A5 JP 2020544351 A JP2020544351 A JP 2020544351A JP 2020544351 A JP2020544351 A JP 2020544351A JP 2021501611 A5 JP2021501611 A5 JP 2021501611A5
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JP
Japan
Prior art keywords
cas12c
nucleic acid
polypeptide
guide rna
acid encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020544351A
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English (en)
Japanese (ja)
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JP2021501611A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/058512 external-priority patent/WO2019089796A1/en
Publication of JP2021501611A publication Critical patent/JP2021501611A/ja
Publication of JP2021501611A5 publication Critical patent/JP2021501611A5/ja
Pending legal-status Critical Current

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JP2020544351A 2017-11-01 2018-10-31 Cas12c組成物及び使用方法 Pending JP2021501611A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762580392P 2017-11-01 2017-11-01
US62/580,392 2017-11-01
PCT/US2018/058512 WO2019089796A1 (en) 2017-11-01 2018-10-31 Cas12c compositions and methods of use

Publications (2)

Publication Number Publication Date
JP2021501611A JP2021501611A (ja) 2021-01-21
JP2021501611A5 true JP2021501611A5 (https=) 2021-12-09

Family

ID=66332737

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020544351A Pending JP2021501611A (ja) 2017-11-01 2018-10-31 Cas12c組成物及び使用方法

Country Status (5)

Country Link
US (1) US20200339967A1 (https=)
EP (1) EP3704254A4 (https=)
JP (1) JP2021501611A (https=)
GB (1) GB2582100B (https=)
WO (1) WO2019089796A1 (https=)

Families Citing this family (25)

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Publication number Priority date Publication date Assignee Title
AU2015330699B2 (en) 2014-10-10 2021-12-02 Editas Medicine, Inc. Compositions and methods for promoting homology directed repair
US10337051B2 (en) 2016-06-16 2019-07-02 The Regents Of The University Of California Methods and compositions for detecting a target RNA
BR112019006388A2 (pt) 2016-09-30 2019-06-25 Univ California enzimas modificadoras de ácido nucleico guiadas por rna e métodos de uso das mesmas
MX2019003674A (es) 2016-09-30 2021-01-08 Univ California Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas.
EP3555297A1 (en) 2016-12-19 2019-10-23 Editas Medicine, Inc. Assessing nuclease cleavage
JP7229923B2 (ja) 2017-01-06 2023-02-28 エディタス・メディシン、インコーポレイテッド ヌクレアーゼ切断を評価する方法
US11499151B2 (en) 2017-04-28 2022-11-15 Editas Medicine, Inc. Methods and systems for analyzing guide RNA molecules
MX2019014640A (es) 2017-06-09 2020-10-05 Editas Medicine Inc Nucleasas de repeticiones palíndromicas agrupadas y regularmente interespaciadas de proteina asociada 9 (cas9) genomanipuladas.
US11866726B2 (en) 2017-07-14 2024-01-09 Editas Medicine, Inc. Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
AU2018358051B2 (en) 2017-11-01 2025-01-09 The Regents Of The University Of California CasZ compositions and methods of use
WO2019089804A1 (en) 2017-11-01 2019-05-09 The Regents Of The University Of California Casy compositions and methods of use
US11970719B2 (en) * 2017-11-01 2024-04-30 The Regents Of The University Of California Class 2 CRISPR/Cas compositions and methods of use
EP3823633A4 (en) 2018-06-29 2023-05-03 Editas Medicine, Inc. SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
EP3830301B1 (en) 2018-08-01 2024-05-22 Mammoth Biosciences, Inc. Programmable nuclease compositions and methods of use thereof
EP3931313A2 (en) 2019-01-04 2022-01-05 Mammoth Biosciences, Inc. Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection
EP4139447A4 (en) * 2020-04-20 2024-05-29 The Regents Of The University Of California CRISPR SYSTEMS IN PLANTS
AU2021353004A1 (en) 2020-09-30 2023-04-13 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
EP4347818A2 (en) 2021-06-01 2024-04-10 Arbor Biotechnologies, Inc. Gene editing systems comprising a crispr nuclease and uses thereof
US12435357B2 (en) 2022-12-22 2025-10-07 Kanso Diagnostics Ltd. Diagnostic device for detecting a target nucleic acid molecule in a biological sample
KR20250151430A (ko) 2023-02-15 2025-10-21 아버 바이오테크놀로지스, 인크. 스타스민 2(stmn2) 전사체에서 비정상적인 스플라이싱을 억제하는 유전자 편집 방법
WO2025171210A1 (en) 2024-02-09 2025-08-14 Arbor Biotechnologies, Inc. Compositions and methods for gene editing via homology-mediated end joining
WO2026015829A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Small reverse transcriptases and gene editing systems comprising such
WO2026015832A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Reverse transcriptases and gene editing systems comprising such

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3155116A4 (en) * 2014-06-10 2017-12-27 Massachusetts Institute Of Technology Method for gene editing
WO2016205749A1 (en) * 2015-06-18 2016-12-22 The Broad Institute Inc. Novel crispr enzymes and systems

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