JP2021501576A5 - - Google Patents

Download PDF

Info

Publication number
JP2021501576A5
JP2021501576A5 JP2020524113A JP2020524113A JP2021501576A5 JP 2021501576 A5 JP2021501576 A5 JP 2021501576A5 JP 2020524113 A JP2020524113 A JP 2020524113A JP 2020524113 A JP2020524113 A JP 2020524113A JP 2021501576 A5 JP2021501576 A5 JP 2021501576A5
Authority
JP
Japan
Prior art keywords
tag
binding
biological
binding substance
library
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020524113A
Other languages
English (en)
Japanese (ja)
Other versions
JP7253833B2 (ja
JP2021501576A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/058583 external-priority patent/WO2019089851A1/en
Publication of JP2021501576A publication Critical patent/JP2021501576A/ja
Publication of JP2021501576A5 publication Critical patent/JP2021501576A5/ja
Application granted granted Critical
Publication of JP7253833B2 publication Critical patent/JP7253833B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020524113A 2017-10-31 2018-10-31 核酸エンコーディングおよび/または標識を使用する方法およびキット Active JP7253833B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762579840P 2017-10-31 2017-10-31
US62/579,840 2017-10-31
US201762582916P 2017-11-07 2017-11-07
US62/582,916 2017-11-07
PCT/US2018/058583 WO2019089851A1 (en) 2017-10-31 2018-10-31 Methods and kits using nucleic acid encoding and/or label

Publications (3)

Publication Number Publication Date
JP2021501576A JP2021501576A (ja) 2021-01-21
JP2021501576A5 true JP2021501576A5 (https=) 2021-12-09
JP7253833B2 JP7253833B2 (ja) 2023-04-07

Family

ID=66332291

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020524113A Active JP7253833B2 (ja) 2017-10-31 2018-10-31 核酸エンコーディングおよび/または標識を使用する方法およびキット

Country Status (7)

Country Link
US (3) US20210355483A1 (https=)
EP (1) EP3704246A4 (https=)
JP (1) JP7253833B2 (https=)
AU (1) AU2018358247A1 (https=)
CA (1) CA3081451A1 (https=)
SG (1) SG11202003923PA (https=)
WO (1) WO2019089851A1 (https=)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
WO2016069124A1 (en) 2014-09-15 2016-05-06 Board Of Regents, The University Of Texas System Improved single molecule peptide sequencing
GB2510488B (en) 2011-06-23 2020-04-08 Univ Texas Identifying peptides at the single molecule level
AU2017259794B2 (en) 2016-05-02 2023-04-13 Encodia, Inc. Macromolecule analysis employing nucleic acid encoding
DK3548652T3 (da) 2016-12-01 2024-07-08 Nautilus Subsidiary Inc Fremgangsmåder til proteinanalyse
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
EP3704246A4 (en) 2017-10-31 2021-08-11 Encodia, Inc. PROCEDURES AND KITS USING NUCLEIC ACID ENCODING AND / OR MARKING
KR20250152680A (ko) 2017-12-29 2025-10-23 노틸러스 서브시디어리, 인크. 단백질 식별을 위한 디코딩 접근법
WO2019195633A1 (en) 2018-04-04 2019-10-10 Ignite Biosciences, Inc. Methods of generating nanoarrays and microarrays
US20210239705A1 (en) * 2018-06-06 2021-08-05 Nautilus Biotechnology, Inc. Methods and applications of protein identification
AU2019301750A1 (en) 2018-07-12 2021-01-28 Board Of Regents, The University Of Texas System Molecular neighborhood detection by oligonucleotides
WO2020051162A1 (en) * 2018-09-04 2020-03-12 Encodia, Inc. Proximity interaction analysis
GB2593091B (en) 2018-10-05 2023-12-20 Univ Texas Solid-phase N-terminal peptide capture and release
EP3884048A4 (en) 2018-11-20 2022-08-17 Nautilus Biotechnology, Inc. DESIGN AND SELECTION OF AFFINITY REAGENTS
CN114126476B (zh) 2019-04-23 2025-09-09 Encodia公司 用于蛋白质的空间分析的方法及相关试剂盒
CA3135206A1 (en) 2019-04-29 2020-11-05 Pierre Indermuhle Methods and systems for integrated on-chip single-molecule detection
EP3963070A4 (en) 2019-04-30 2023-02-22 Encodia, Inc. METHODS OF PREPARATION OF ANALYTES AND RELATED KITS
EP3973299A4 (en) * 2019-05-20 2023-04-19 Encodia, Inc. METHODS AND RELATED KITS FOR SPATIAL ANALYSIS
WO2021087402A1 (en) 2019-10-30 2021-05-06 Nautilus Biotechnology, Inc. Flow cell systems and methods
PH12021553295A1 (en) * 2019-12-23 2022-08-01 Illumina Cambridge Ltd Nanoparticle with single site for template polynucleotide attachment
WO2021141922A1 (en) * 2020-01-07 2021-07-15 Encodia, Inc. Methods for information transfer and related kits
WO2021141924A1 (en) 2020-01-07 2021-07-15 Encodia, Inc. Methods for stable complex formation and related kits
EP4073263A4 (en) 2020-01-07 2023-11-08 Encodia, Inc. METHOD FOR STABLE COMPLEX FORMATION AND CORRESPONDING KITS
EP4103741A4 (en) * 2020-02-12 2024-03-20 Universal Sequencing Technology Corporation INTRACELLULAR AND SPATIAL BAR CODING PROCESSES
US12571802B2 (en) * 2020-02-29 2026-03-10 President And Fellows Of Harvard College Nanoswitch caliper trains for high-throughput, high-resolution structural analysis of biomolecules
WO2022040098A1 (en) 2020-08-19 2022-02-24 Encodia, Inc. Sequential encoding methods and related kits
WO2022067019A1 (en) * 2020-09-26 2022-03-31 The Regents Of The University Of California Hybrid protocols and barcoding schemes for multiple sequencing technologies
US20230220589A1 (en) * 2020-09-30 2023-07-13 Encodia, Inc. Polypeptide terminal binders and uses thereof
CA3196729A1 (en) 2020-11-11 2022-05-19 Tural AKSEL Affinity reagents having enhanced binding and detection characteristics
US12497651B2 (en) 2020-11-23 2025-12-16 Pleno, Inc. Encoded dual-probe endonuclease assays
WO2023096675A1 (en) * 2021-11-23 2023-06-01 Pleno, Inc. Encoded endonuclease assays
JP2023551072A (ja) 2020-11-25 2023-12-06 アリダ・バイオサイエンシーズ・インコーポレイテッド Rnaおよびdna修飾の多重プロファイリング
EP4348267A2 (en) * 2021-05-26 2024-04-10 Board of Regents, The University of Texas System Compositions, methods, and utility of conjugated biomolecule barcodes
CN113908589B (zh) * 2021-10-08 2022-09-27 天津工业大学 一种表面印迹抗体的疏水电荷诱导模式膜层析介质及其制备方法
US12474346B2 (en) 2021-11-05 2025-11-18 Encodia, Inc. Methods and kits for multicycle encoding assay
WO2023097295A1 (en) 2021-11-24 2023-06-01 Alida Biosciences, Inc. Rna and dna analysis using engineered surfaces
WO2023122698A1 (en) * 2021-12-21 2023-06-29 Encodia, Inc. Methods for balancing encoding signals of analytes
EP4453244A4 (en) * 2021-12-23 2025-12-24 Takara Bio Usa Inc METHODS AND COMPOSITIONS FOR THE PRODUCTION OF IDENTIFIABLE NUCLEIC ACID COLLECTIONS FROM CELLULAR SOURCES
US12043862B2 (en) * 2021-12-28 2024-07-23 Encodia, Inc. High-throughput serotyping and antibody profiling assays
EP4565882A1 (en) 2022-08-02 2025-06-11 Glyphic Biotechnologies, Inc. Protein sequencing via coupling of polymerizable molecules
WO2024040236A2 (en) 2022-08-19 2024-02-22 Abrus Bio, Inc. Determination of protein information by recoding amino acid polymers into dna polymers
WO2024050553A1 (en) * 2022-09-01 2024-03-07 The Johns Hopkins University Methods for measuring telomere length
WO2024123807A1 (en) * 2022-12-06 2024-06-13 Shifeng Li Methods and apparatus for protein and peptide sequencing
CN115881218B (zh) * 2022-12-15 2023-06-09 哈尔滨星云医学检验所有限公司 用于全基因组关联分析的基因自动选择方法
WO2024138170A1 (en) * 2022-12-23 2024-06-27 Illumina, Inc. Spatial mrna/protein co-assays using aptamers
US20240327902A1 (en) * 2023-03-31 2024-10-03 Shifeng Li Methods for detecting and analysis of proteins
WO2025085861A1 (en) * 2023-10-20 2025-04-24 Spectral Therapeutics, Inc. Composite particles for use in generating spectrally encoded libraries of chemical compounds, and methods of making and using the same
US20250154584A1 (en) * 2023-11-09 2025-05-15 Encodia, Inc. Methods for identifying polypeptides
WO2025144972A1 (en) * 2023-12-29 2025-07-03 Illumina, Inc. Materials and methods for preparation of a spatial transcriptomics library

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US6875851B1 (en) 1999-03-05 2005-04-05 University Of Georgia Research Foundation, Inc. Prolyl tripeptidyl peptidases nucleic acid of Porphyromonas gingivalis
DE60029572T2 (de) 1999-03-23 2007-07-26 Biovation Ltd. Isolierung und analyse von proteinen
US7306904B2 (en) 2000-02-18 2007-12-11 Olink Ab Methods and kits for proximity probing
US6511809B2 (en) 2000-06-13 2003-01-28 E. I. Du Pont De Nemours And Company Method for the detection of an analyte by means of a nucleic acid reporter
EP1360490B1 (en) 2001-01-23 2011-12-21 President and Fellows of Harvard College Nucleic-acid programmable protein arrays
EP1401850A1 (en) 2001-06-20 2004-03-31 Nuevolution A/S Nucleoside derivatives for library preparation
US8013134B2 (en) 2001-11-23 2011-09-06 Olink Ab Kit for proximity probing with multivalent proximity probes
EP1578935A2 (en) 2002-10-10 2005-09-28 Diversa Corporation Proteases, nucleic acids encoding them and methods for making and using them
WO2005015239A2 (en) 2003-08-07 2005-02-17 Cornell Research Foundation, Inc. Method for n-terminal labeling of proteins
US7198900B2 (en) 2003-08-29 2007-04-03 Applera Corporation Multiplex detection compositions, methods, and kits
EP1670939B1 (en) * 2003-09-18 2009-11-04 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
US7579165B2 (en) 2003-10-16 2009-08-25 Shimadzu Corporation Methods for derivatizing protein or peptide with sulfonic acid groups
CN1898257B (zh) 2003-12-17 2010-06-23 普雷西斯药品公司 合成编码文库的方法
DE602005017370D1 (de) 2004-03-22 2009-12-10 Nuevolution As Ligationscodierung unter verwendung von oligonukleotidbausteinen
CA2563168A1 (en) 2004-04-14 2005-11-17 President And Fellows Of Harvard College Nucleic-acid programmable protein arrays
US20060199279A1 (en) 2005-03-07 2006-09-07 Viorica Lopez-Avila Methods for identifying post-translationally modified polypeptides
US7883848B2 (en) 2005-07-08 2011-02-08 Olink Ab Regulation analysis by cis reactivity, RACR
HUE056836T2 (hu) * 2005-12-01 2022-03-28 Nuevolution As Enzimatikus kódolási eljárások nagy könyvtárak hatékony szintéziséhez
WO2009050261A1 (en) 2007-10-19 2009-04-23 Pronota N.V. Preparation of samples for proteome analysis
WO2010065322A1 (en) 2008-12-01 2010-06-10 Research Triangle Institute Concurrent identification of multitudes of polypeptides
WO2010127186A1 (en) 2009-04-30 2010-11-04 Prognosys Biosciences, Inc. Nucleic acid constructs and methods of use
WO2011056185A2 (en) 2009-11-04 2011-05-12 President And Fellows Of Harvard College Reactivity-dependent and interaction-dependent pcr
US20120270748A1 (en) 2009-12-07 2012-10-25 Prognosys Biosciences, Inc. Peptide display arrays
US20110245101A1 (en) 2010-04-05 2011-10-06 Prognosys Biosciences, Inc. Co-localization affinity assays
GB201101621D0 (en) 2011-01-31 2011-03-16 Olink Ab Method and product
EP2694709B1 (en) 2011-04-08 2016-09-14 Prognosys Biosciences, Inc. Peptide constructs and assay systems
WO2016069124A1 (en) 2014-09-15 2016-05-06 Board Of Regents, The University Of Texas System Improved single molecule peptide sequencing
US20130052665A1 (en) 2011-08-25 2013-02-28 Bruce Xuefeng Ling Methods for diagnosis of systemic juvenile idiopathic arthritis
US9335292B2 (en) 2011-10-13 2016-05-10 Auburn University Electrochemical proximity assay
US9435810B2 (en) 2013-03-15 2016-09-06 Washington University Molecules and methods for iterative polypeptide analysis and processing
US10053725B2 (en) 2013-04-23 2018-08-21 President And Fellows Of Harvard College In situ interaction determination
WO2015070037A2 (en) * 2013-11-08 2015-05-14 Prognosys Biosciences, Inc. Polynucleotide conjugates and methods for analyte detection
US9834814B2 (en) * 2013-11-22 2017-12-05 Agilent Technologies, Inc. Spatial molecular barcoding of in situ nucleic acids
US10858698B2 (en) 2014-03-25 2020-12-08 President And Fellows Of Harvard College Barcoded protein array for multiplex single-molecule interaction profiling
WO2015176034A1 (en) 2014-05-15 2015-11-19 Two Pore Guys, Inc. Scaffold data storage and target detection in a sample using a nanopore
CN113249435B (zh) 2014-06-26 2024-09-03 10X基因组学有限公司 分析来自单个细胞或细胞群体的核酸的方法
US20170212101A1 (en) 2014-07-18 2017-07-27 Cdi Laboratories, Inc. Methods and compositions to identify, quantify, and characterize target analytes and binding moieties
CA2956925C (en) 2014-08-01 2024-02-13 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
NZ734644A (en) * 2015-02-24 2023-02-24 Hope City Chemically encoded spatially addressed library screening platforms
WO2016138496A1 (en) 2015-02-27 2016-09-01 Cellular Research, Inc. Spatially addressable molecular barcoding
WO2016145416A2 (en) 2015-03-11 2016-09-15 The Broad Institute, Inc. Proteomic analysis with nucleic acid identifiers
AU2017259794B2 (en) 2016-05-02 2023-04-13 Encodia, Inc. Macromolecule analysis employing nucleic acid encoding
WO2018005720A1 (en) 2016-06-30 2018-01-04 President And Fellows Of Harvard College Method of determining the molecular binding between libraries of molecules
CN109923216B (zh) 2016-08-31 2024-08-02 哈佛学院董事及会员团体 将生物分子的检测组合到使用荧光原位测序的单个试验的方法
CN110214186B (zh) 2017-01-30 2023-11-24 10X基因组学有限公司 用于基于微滴的单细胞条形编码的方法和系统
EP3583214B1 (en) 2017-02-02 2023-11-22 New York Genome Center, Inc. Methods and compositions for identifying or quantifying targets in a biological sample
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
EP3704246A4 (en) 2017-10-31 2021-08-11 Encodia, Inc. PROCEDURES AND KITS USING NUCLEIC ACID ENCODING AND / OR MARKING
WO2019089846A1 (en) 2017-10-31 2019-05-09 Encodia, Inc. Methods and compositions for polypeptide analysis
KR20250152680A (ko) 2017-12-29 2025-10-23 노틸러스 서브시디어리, 인크. 단백질 식별을 위한 디코딩 접근법

Similar Documents

Publication Publication Date Title
JP2021501576A5 (https=)
US11667956B2 (en) Methods of identifying multiple epitopes in cells
US20230081326A1 (en) Increasing dynamic range for identifying multiple epitopes in cells
US20220333096A1 (en) Methods for the production of long length clonal sequence verified nucleic acid constructs
US7901886B2 (en) Microfluidic extraction method
Uttamchandani et al. Protein and small molecule microarrays: powerful tools for high-throughput proteomics
JP2021501577A5 (https=)
Kodadek Development of protein-detecting microarrays and related devices
JP2019523635A5 (https=)
Breitling et al. High-density peptide arrays
US20220056515A1 (en) Methods of identifying multiple epitopes in cells
CN116024307A (zh) 一种含组织位置信息的单细胞文库构建方法及测序方法
US20200157603A1 (en) Methods of identifying multiple epitopes in cells
JP5733784B2 (ja) cDNA/mRNA−タンパク質連結体の効率的合成法
US20100256012A1 (en) Flexible extraction method for the production of sequence-specific molecule libraries
Weiner et al. Protein, antibody and small molecule microarrays