JP2021501576A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021501576A5 JP2021501576A5 JP2020524113A JP2020524113A JP2021501576A5 JP 2021501576 A5 JP2021501576 A5 JP 2021501576A5 JP 2020524113 A JP2020524113 A JP 2020524113A JP 2020524113 A JP2020524113 A JP 2020524113A JP 2021501576 A5 JP2021501576 A5 JP 2021501576A5
- Authority
- JP
- Japan
- Prior art keywords
- tag
- binding
- biological
- binding substance
- library
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762579840P | 2017-10-31 | 2017-10-31 | |
| US62/579,840 | 2017-10-31 | ||
| US201762582916P | 2017-11-07 | 2017-11-07 | |
| US62/582,916 | 2017-11-07 | ||
| PCT/US2018/058583 WO2019089851A1 (en) | 2017-10-31 | 2018-10-31 | Methods and kits using nucleic acid encoding and/or label |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021501576A JP2021501576A (ja) | 2021-01-21 |
| JP2021501576A5 true JP2021501576A5 (https=) | 2021-12-09 |
| JP7253833B2 JP7253833B2 (ja) | 2023-04-07 |
Family
ID=66332291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020524113A Active JP7253833B2 (ja) | 2017-10-31 | 2018-10-31 | 核酸エンコーディングおよび/または標識を使用する方法およびキット |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20210355483A1 (https=) |
| EP (1) | EP3704246A4 (https=) |
| JP (1) | JP7253833B2 (https=) |
| AU (1) | AU2018358247A1 (https=) |
| CA (1) | CA3081451A1 (https=) |
| SG (1) | SG11202003923PA (https=) |
| WO (1) | WO2019089851A1 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
| WO2016069124A1 (en) | 2014-09-15 | 2016-05-06 | Board Of Regents, The University Of Texas System | Improved single molecule peptide sequencing |
| GB2510488B (en) | 2011-06-23 | 2020-04-08 | Univ Texas | Identifying peptides at the single molecule level |
| AU2017259794B2 (en) | 2016-05-02 | 2023-04-13 | Encodia, Inc. | Macromolecule analysis employing nucleic acid encoding |
| DK3548652T3 (da) | 2016-12-01 | 2024-07-08 | Nautilus Subsidiary Inc | Fremgangsmåder til proteinanalyse |
| MX2020004559A (es) | 2017-10-31 | 2020-10-05 | Encodia Inc | Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico. |
| EP3704246A4 (en) | 2017-10-31 | 2021-08-11 | Encodia, Inc. | PROCEDURES AND KITS USING NUCLEIC ACID ENCODING AND / OR MARKING |
| KR20250152680A (ko) | 2017-12-29 | 2025-10-23 | 노틸러스 서브시디어리, 인크. | 단백질 식별을 위한 디코딩 접근법 |
| WO2019195633A1 (en) | 2018-04-04 | 2019-10-10 | Ignite Biosciences, Inc. | Methods of generating nanoarrays and microarrays |
| US20210239705A1 (en) * | 2018-06-06 | 2021-08-05 | Nautilus Biotechnology, Inc. | Methods and applications of protein identification |
| AU2019301750A1 (en) | 2018-07-12 | 2021-01-28 | Board Of Regents, The University Of Texas System | Molecular neighborhood detection by oligonucleotides |
| WO2020051162A1 (en) * | 2018-09-04 | 2020-03-12 | Encodia, Inc. | Proximity interaction analysis |
| GB2593091B (en) | 2018-10-05 | 2023-12-20 | Univ Texas | Solid-phase N-terminal peptide capture and release |
| EP3884048A4 (en) | 2018-11-20 | 2022-08-17 | Nautilus Biotechnology, Inc. | DESIGN AND SELECTION OF AFFINITY REAGENTS |
| CN114126476B (zh) | 2019-04-23 | 2025-09-09 | Encodia公司 | 用于蛋白质的空间分析的方法及相关试剂盒 |
| CA3135206A1 (en) | 2019-04-29 | 2020-11-05 | Pierre Indermuhle | Methods and systems for integrated on-chip single-molecule detection |
| EP3963070A4 (en) | 2019-04-30 | 2023-02-22 | Encodia, Inc. | METHODS OF PREPARATION OF ANALYTES AND RELATED KITS |
| EP3973299A4 (en) * | 2019-05-20 | 2023-04-19 | Encodia, Inc. | METHODS AND RELATED KITS FOR SPATIAL ANALYSIS |
| WO2021087402A1 (en) | 2019-10-30 | 2021-05-06 | Nautilus Biotechnology, Inc. | Flow cell systems and methods |
| PH12021553295A1 (en) * | 2019-12-23 | 2022-08-01 | Illumina Cambridge Ltd | Nanoparticle with single site for template polynucleotide attachment |
| WO2021141922A1 (en) * | 2020-01-07 | 2021-07-15 | Encodia, Inc. | Methods for information transfer and related kits |
| WO2021141924A1 (en) | 2020-01-07 | 2021-07-15 | Encodia, Inc. | Methods for stable complex formation and related kits |
| EP4073263A4 (en) | 2020-01-07 | 2023-11-08 | Encodia, Inc. | METHOD FOR STABLE COMPLEX FORMATION AND CORRESPONDING KITS |
| EP4103741A4 (en) * | 2020-02-12 | 2024-03-20 | Universal Sequencing Technology Corporation | INTRACELLULAR AND SPATIAL BAR CODING PROCESSES |
| US12571802B2 (en) * | 2020-02-29 | 2026-03-10 | President And Fellows Of Harvard College | Nanoswitch caliper trains for high-throughput, high-resolution structural analysis of biomolecules |
| WO2022040098A1 (en) | 2020-08-19 | 2022-02-24 | Encodia, Inc. | Sequential encoding methods and related kits |
| WO2022067019A1 (en) * | 2020-09-26 | 2022-03-31 | The Regents Of The University Of California | Hybrid protocols and barcoding schemes for multiple sequencing technologies |
| US20230220589A1 (en) * | 2020-09-30 | 2023-07-13 | Encodia, Inc. | Polypeptide terminal binders and uses thereof |
| CA3196729A1 (en) | 2020-11-11 | 2022-05-19 | Tural AKSEL | Affinity reagents having enhanced binding and detection characteristics |
| US12497651B2 (en) | 2020-11-23 | 2025-12-16 | Pleno, Inc. | Encoded dual-probe endonuclease assays |
| WO2023096675A1 (en) * | 2021-11-23 | 2023-06-01 | Pleno, Inc. | Encoded endonuclease assays |
| JP2023551072A (ja) | 2020-11-25 | 2023-12-06 | アリダ・バイオサイエンシーズ・インコーポレイテッド | Rnaおよびdna修飾の多重プロファイリング |
| EP4348267A2 (en) * | 2021-05-26 | 2024-04-10 | Board of Regents, The University of Texas System | Compositions, methods, and utility of conjugated biomolecule barcodes |
| CN113908589B (zh) * | 2021-10-08 | 2022-09-27 | 天津工业大学 | 一种表面印迹抗体的疏水电荷诱导模式膜层析介质及其制备方法 |
| US12474346B2 (en) | 2021-11-05 | 2025-11-18 | Encodia, Inc. | Methods and kits for multicycle encoding assay |
| WO2023097295A1 (en) | 2021-11-24 | 2023-06-01 | Alida Biosciences, Inc. | Rna and dna analysis using engineered surfaces |
| WO2023122698A1 (en) * | 2021-12-21 | 2023-06-29 | Encodia, Inc. | Methods for balancing encoding signals of analytes |
| EP4453244A4 (en) * | 2021-12-23 | 2025-12-24 | Takara Bio Usa Inc | METHODS AND COMPOSITIONS FOR THE PRODUCTION OF IDENTIFIABLE NUCLEIC ACID COLLECTIONS FROM CELLULAR SOURCES |
| US12043862B2 (en) * | 2021-12-28 | 2024-07-23 | Encodia, Inc. | High-throughput serotyping and antibody profiling assays |
| EP4565882A1 (en) | 2022-08-02 | 2025-06-11 | Glyphic Biotechnologies, Inc. | Protein sequencing via coupling of polymerizable molecules |
| WO2024040236A2 (en) | 2022-08-19 | 2024-02-22 | Abrus Bio, Inc. | Determination of protein information by recoding amino acid polymers into dna polymers |
| WO2024050553A1 (en) * | 2022-09-01 | 2024-03-07 | The Johns Hopkins University | Methods for measuring telomere length |
| WO2024123807A1 (en) * | 2022-12-06 | 2024-06-13 | Shifeng Li | Methods and apparatus for protein and peptide sequencing |
| CN115881218B (zh) * | 2022-12-15 | 2023-06-09 | 哈尔滨星云医学检验所有限公司 | 用于全基因组关联分析的基因自动选择方法 |
| WO2024138170A1 (en) * | 2022-12-23 | 2024-06-27 | Illumina, Inc. | Spatial mrna/protein co-assays using aptamers |
| US20240327902A1 (en) * | 2023-03-31 | 2024-10-03 | Shifeng Li | Methods for detecting and analysis of proteins |
| WO2025085861A1 (en) * | 2023-10-20 | 2025-04-24 | Spectral Therapeutics, Inc. | Composite particles for use in generating spectrally encoded libraries of chemical compounds, and methods of making and using the same |
| US20250154584A1 (en) * | 2023-11-09 | 2025-05-15 | Encodia, Inc. | Methods for identifying polypeptides |
| WO2025144972A1 (en) * | 2023-12-29 | 2025-07-03 | Illumina, Inc. | Materials and methods for preparation of a spatial transcriptomics library |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US6875851B1 (en) | 1999-03-05 | 2005-04-05 | University Of Georgia Research Foundation, Inc. | Prolyl tripeptidyl peptidases nucleic acid of Porphyromonas gingivalis |
| DE60029572T2 (de) | 1999-03-23 | 2007-07-26 | Biovation Ltd. | Isolierung und analyse von proteinen |
| US7306904B2 (en) | 2000-02-18 | 2007-12-11 | Olink Ab | Methods and kits for proximity probing |
| US6511809B2 (en) | 2000-06-13 | 2003-01-28 | E. I. Du Pont De Nemours And Company | Method for the detection of an analyte by means of a nucleic acid reporter |
| EP1360490B1 (en) | 2001-01-23 | 2011-12-21 | President and Fellows of Harvard College | Nucleic-acid programmable protein arrays |
| EP1401850A1 (en) | 2001-06-20 | 2004-03-31 | Nuevolution A/S | Nucleoside derivatives for library preparation |
| US8013134B2 (en) | 2001-11-23 | 2011-09-06 | Olink Ab | Kit for proximity probing with multivalent proximity probes |
| EP1578935A2 (en) | 2002-10-10 | 2005-09-28 | Diversa Corporation | Proteases, nucleic acids encoding them and methods for making and using them |
| WO2005015239A2 (en) | 2003-08-07 | 2005-02-17 | Cornell Research Foundation, Inc. | Method for n-terminal labeling of proteins |
| US7198900B2 (en) | 2003-08-29 | 2007-04-03 | Applera Corporation | Multiplex detection compositions, methods, and kits |
| EP1670939B1 (en) * | 2003-09-18 | 2009-11-04 | Nuevolution A/S | A method for obtaining structural information concerning an encoded molecule and method for selecting compounds |
| US7579165B2 (en) | 2003-10-16 | 2009-08-25 | Shimadzu Corporation | Methods for derivatizing protein or peptide with sulfonic acid groups |
| CN1898257B (zh) | 2003-12-17 | 2010-06-23 | 普雷西斯药品公司 | 合成编码文库的方法 |
| DE602005017370D1 (de) | 2004-03-22 | 2009-12-10 | Nuevolution As | Ligationscodierung unter verwendung von oligonukleotidbausteinen |
| CA2563168A1 (en) | 2004-04-14 | 2005-11-17 | President And Fellows Of Harvard College | Nucleic-acid programmable protein arrays |
| US20060199279A1 (en) | 2005-03-07 | 2006-09-07 | Viorica Lopez-Avila | Methods for identifying post-translationally modified polypeptides |
| US7883848B2 (en) | 2005-07-08 | 2011-02-08 | Olink Ab | Regulation analysis by cis reactivity, RACR |
| HUE056836T2 (hu) * | 2005-12-01 | 2022-03-28 | Nuevolution As | Enzimatikus kódolási eljárások nagy könyvtárak hatékony szintéziséhez |
| WO2009050261A1 (en) | 2007-10-19 | 2009-04-23 | Pronota N.V. | Preparation of samples for proteome analysis |
| WO2010065322A1 (en) | 2008-12-01 | 2010-06-10 | Research Triangle Institute | Concurrent identification of multitudes of polypeptides |
| WO2010127186A1 (en) | 2009-04-30 | 2010-11-04 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
| WO2011056185A2 (en) | 2009-11-04 | 2011-05-12 | President And Fellows Of Harvard College | Reactivity-dependent and interaction-dependent pcr |
| US20120270748A1 (en) | 2009-12-07 | 2012-10-25 | Prognosys Biosciences, Inc. | Peptide display arrays |
| US20110245101A1 (en) | 2010-04-05 | 2011-10-06 | Prognosys Biosciences, Inc. | Co-localization affinity assays |
| GB201101621D0 (en) | 2011-01-31 | 2011-03-16 | Olink Ab | Method and product |
| EP2694709B1 (en) | 2011-04-08 | 2016-09-14 | Prognosys Biosciences, Inc. | Peptide constructs and assay systems |
| WO2016069124A1 (en) | 2014-09-15 | 2016-05-06 | Board Of Regents, The University Of Texas System | Improved single molecule peptide sequencing |
| US20130052665A1 (en) | 2011-08-25 | 2013-02-28 | Bruce Xuefeng Ling | Methods for diagnosis of systemic juvenile idiopathic arthritis |
| US9335292B2 (en) | 2011-10-13 | 2016-05-10 | Auburn University | Electrochemical proximity assay |
| US9435810B2 (en) | 2013-03-15 | 2016-09-06 | Washington University | Molecules and methods for iterative polypeptide analysis and processing |
| US10053725B2 (en) | 2013-04-23 | 2018-08-21 | President And Fellows Of Harvard College | In situ interaction determination |
| WO2015070037A2 (en) * | 2013-11-08 | 2015-05-14 | Prognosys Biosciences, Inc. | Polynucleotide conjugates and methods for analyte detection |
| US9834814B2 (en) * | 2013-11-22 | 2017-12-05 | Agilent Technologies, Inc. | Spatial molecular barcoding of in situ nucleic acids |
| US10858698B2 (en) | 2014-03-25 | 2020-12-08 | President And Fellows Of Harvard College | Barcoded protein array for multiplex single-molecule interaction profiling |
| WO2015176034A1 (en) | 2014-05-15 | 2015-11-19 | Two Pore Guys, Inc. | Scaffold data storage and target detection in a sample using a nanopore |
| CN113249435B (zh) | 2014-06-26 | 2024-09-03 | 10X基因组学有限公司 | 分析来自单个细胞或细胞群体的核酸的方法 |
| US20170212101A1 (en) | 2014-07-18 | 2017-07-27 | Cdi Laboratories, Inc. | Methods and compositions to identify, quantify, and characterize target analytes and binding moieties |
| CA2956925C (en) | 2014-08-01 | 2024-02-13 | Dovetail Genomics, Llc | Tagging nucleic acids for sequence assembly |
| NZ734644A (en) * | 2015-02-24 | 2023-02-24 | Hope City | Chemically encoded spatially addressed library screening platforms |
| WO2016138496A1 (en) | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Spatially addressable molecular barcoding |
| WO2016145416A2 (en) | 2015-03-11 | 2016-09-15 | The Broad Institute, Inc. | Proteomic analysis with nucleic acid identifiers |
| AU2017259794B2 (en) | 2016-05-02 | 2023-04-13 | Encodia, Inc. | Macromolecule analysis employing nucleic acid encoding |
| WO2018005720A1 (en) | 2016-06-30 | 2018-01-04 | President And Fellows Of Harvard College | Method of determining the molecular binding between libraries of molecules |
| CN109923216B (zh) | 2016-08-31 | 2024-08-02 | 哈佛学院董事及会员团体 | 将生物分子的检测组合到使用荧光原位测序的单个试验的方法 |
| CN110214186B (zh) | 2017-01-30 | 2023-11-24 | 10X基因组学有限公司 | 用于基于微滴的单细胞条形编码的方法和系统 |
| EP3583214B1 (en) | 2017-02-02 | 2023-11-22 | New York Genome Center, Inc. | Methods and compositions for identifying or quantifying targets in a biological sample |
| MX2020004559A (es) | 2017-10-31 | 2020-10-05 | Encodia Inc | Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico. |
| EP3704246A4 (en) | 2017-10-31 | 2021-08-11 | Encodia, Inc. | PROCEDURES AND KITS USING NUCLEIC ACID ENCODING AND / OR MARKING |
| WO2019089846A1 (en) | 2017-10-31 | 2019-05-09 | Encodia, Inc. | Methods and compositions for polypeptide analysis |
| KR20250152680A (ko) | 2017-12-29 | 2025-10-23 | 노틸러스 서브시디어리, 인크. | 단백질 식별을 위한 디코딩 접근법 |
-
2018
- 2018-10-31 EP EP18872456.1A patent/EP3704246A4/en active Pending
- 2018-10-31 US US16/760,032 patent/US20210355483A1/en not_active Abandoned
- 2018-10-31 WO PCT/US2018/058583 patent/WO2019089851A1/en not_active Ceased
- 2018-10-31 SG SG11202003923PA patent/SG11202003923PA/en unknown
- 2018-10-31 JP JP2020524113A patent/JP7253833B2/ja active Active
- 2018-10-31 CA CA3081451A patent/CA3081451A1/en active Pending
- 2018-10-31 AU AU2018358247A patent/AU2018358247A1/en not_active Abandoned
-
2023
- 2023-03-22 US US18/125,075 patent/US12129463B2/en active Active
-
2024
- 2024-08-09 US US18/799,749 patent/US12467049B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021501576A5 (https=) | ||
| US11667956B2 (en) | Methods of identifying multiple epitopes in cells | |
| US20230081326A1 (en) | Increasing dynamic range for identifying multiple epitopes in cells | |
| US20220333096A1 (en) | Methods for the production of long length clonal sequence verified nucleic acid constructs | |
| US7901886B2 (en) | Microfluidic extraction method | |
| Uttamchandani et al. | Protein and small molecule microarrays: powerful tools for high-throughput proteomics | |
| JP2021501577A5 (https=) | ||
| Kodadek | Development of protein-detecting microarrays and related devices | |
| JP2019523635A5 (https=) | ||
| Breitling et al. | High-density peptide arrays | |
| US20220056515A1 (en) | Methods of identifying multiple epitopes in cells | |
| CN116024307A (zh) | 一种含组织位置信息的单细胞文库构建方法及测序方法 | |
| US20200157603A1 (en) | Methods of identifying multiple epitopes in cells | |
| JP5733784B2 (ja) | cDNA/mRNA−タンパク質連結体の効率的合成法 | |
| US20100256012A1 (en) | Flexible extraction method for the production of sequence-specific molecule libraries | |
| Weiner et al. | Protein, antibody and small molecule microarrays |