JP2021500349A5 - - Google Patents

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JP2021500349A5
JP2021500349A5 JP2020522016A JP2020522016A JP2021500349A5 JP 2021500349 A5 JP2021500349 A5 JP 2021500349A5 JP 2020522016 A JP2020522016 A JP 2020522016A JP 2020522016 A JP2020522016 A JP 2020522016A JP 2021500349 A5 JP2021500349 A5 JP 2021500349A5
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antibody
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composition according
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JP2020522016A
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JP2021500349A (ja
JP7308191B2 (ja
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Priority claimed from PCT/US2018/056441 external-priority patent/WO2019079548A1/en
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JP2020522016A 2017-10-18 2018-10-18 抗cd47剤ベースの卵巣癌療法 Active JP7308191B2 (ja)

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Application Number Priority Date Filing Date Title
JP2022186406A JP2023018062A (ja) 2017-10-18 2022-11-22 抗cd47剤ベースの卵巣癌療法

Applications Claiming Priority (3)

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US201762573835P 2017-10-18 2017-10-18
US62/573,835 2017-10-18
PCT/US2018/056441 WO2019079548A1 (en) 2017-10-18 2018-10-18 OVARIAN CANCER THERAPY BASED ON ANTI-CD47 AGENT

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JP2022186406A Division JP2023018062A (ja) 2017-10-18 2022-11-22 抗cd47剤ベースの卵巣癌療法

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JP2021500349A JP2021500349A (ja) 2021-01-07
JP2021500349A5 true JP2021500349A5 (https=) 2021-10-07
JP7308191B2 JP7308191B2 (ja) 2023-07-13

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JP2020522016A Active JP7308191B2 (ja) 2017-10-18 2018-10-18 抗cd47剤ベースの卵巣癌療法
JP2022186406A Pending JP2023018062A (ja) 2017-10-18 2022-11-22 抗cd47剤ベースの卵巣癌療法

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US (2) US11802153B2 (https=)
EP (2) EP3697817B1 (https=)
JP (2) JP7308191B2 (https=)
KR (1) KR102776457B1 (https=)
CN (2) CN117771364A (https=)
AU (1) AU2018351006B2 (https=)
CA (1) CA3078253A1 (https=)
ES (2) ES2932286T3 (https=)
PL (2) PL3697817T3 (https=)
PT (2) PT4177270T (https=)
SI (2) SI4177270T1 (https=)
WO (1) WO2019079548A1 (https=)

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EP3747906A1 (en) 2016-01-11 2020-12-09 Forty Seven, Inc. Humanized, mouse or chimeric anti-cd47 monoclonal antibodies
SI4177270T1 (sl) 2017-10-18 2024-10-30 Forty Seven, Inc. Terapija za raka jajčnikov na osnovi sredstva proti cd47
AU2019218271B2 (en) 2018-02-12 2024-12-12 Forty Seven, LLC Anti-cancer regimen using anti-CD47 and anti-CD20 antibodies
JP7557920B2 (ja) * 2018-09-04 2024-09-30 ファイザー・インク 疾患治療のためのparp阻害と組み合わせたcd47遮断
JP7369297B2 (ja) 2019-12-17 2023-10-25 ファイザー・インク Cd47、pd-l1に特異的な抗体、およびその使用
PE20230116A1 (es) * 2020-04-06 2023-01-27 Univ Leland Stanford Junior Formulacion de anticuerpos
US20230014026A1 (en) * 2020-06-22 2023-01-19 Morphosys Ag Anti-Tumor Combination Therapy comprising Anti-CD19 Antibody and Polypeptides Blocking the SIRPalpha-CD47 Innate Immune Checkpoint
WO2022171121A1 (zh) * 2021-02-10 2022-08-18 同润生物医药(上海)有限公司 治疗肿瘤的方法和组合
BR112023018450A2 (pt) * 2021-04-14 2023-11-07 Akeso Biopharma Inc Anticorpo monoclonal anti-cd47 e seu uso
US20240254226A1 (en) * 2021-06-10 2024-08-01 Ono Pharmaceutical Co., Ltd. Cancer treatment method by combined use of cd47 inhibitory substance, immune checkpoint inhibitory substance, and standard therapy
CN115245516A (zh) * 2021-12-31 2022-10-28 郑州大学第一附属医院 一种抗卵巢癌肿瘤药物联用方法、体外和体内验证方法
US20250228938A1 (en) * 2022-03-08 2025-07-17 Whitehead Institute For Biomedical Research The combination of macrophage-directed immunotherapy and targeted agents for treatment of cancer
TWI876305B (zh) * 2022-04-05 2025-03-11 美商基利科學股份有限公司 用於治療結腸直腸癌之組合療法

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AU2009205665B2 (en) 2008-01-15 2013-12-05 The Board Of Trustees Of The Leland Stanford Junior University Methods for manipulating phagocytosis mediated by CD47
EP2477648B1 (en) 2009-09-15 2022-07-20 The Board of Trustees of the Leland Stanford Junior University Synergistic anti-cd47 therapy for hematologic cancers
WO2011041453A1 (en) 2009-09-29 2011-04-07 The Board Of Trustees Of The Leland Stanford Junior University Isolation and use of melanoma cancer stem cells
HRP20221260T1 (hr) 2010-05-14 2023-03-03 The Board Of Trustees Of The Leland Stanford Junior University Humanizirana i kimerna monoklonska protutijela za cd47
WO2012088309A1 (en) 2010-12-21 2012-06-28 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic and diagnostic methods for manipulating phagocytosis through calreticulin and low density lipoprotein-related receptor
SI2804617T1 (sl) 2012-01-17 2020-10-30 The Board Of Trustees Of The Leland Stanford Junior University Visokoafinitetni SIRP-alfa reagenti
MX2015007446A (es) 2012-12-12 2015-12-07 Vasculox Inc Anticuerpos terapeuticos para cd47.
PT2970493T (pt) 2013-03-15 2019-06-27 Univ Leland Stanford Junior Métodos para obter doses terapeuticamente eficazes de agentes anti-cd47
ES2898627T3 (es) 2013-04-29 2022-03-08 Univ Leland Stanford Junior Uso de agentes anti-CD47 para mejorar la inmunización
WO2014186761A2 (en) 2013-05-17 2014-11-20 The Board Of Trustes Of The Leland Stanford Junior University Methods for determining responsiveness to an anti-cd47 agent
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EP3209769B1 (en) 2014-10-24 2020-08-05 The Board of Trustees of the Leland Stanford Junior University Compositions and methods for inducing phagocytosis of mhc class i positive cells and countering anti-cd47/sirpa resistance
TWI595006B (zh) 2014-12-09 2017-08-11 禮納特神經系統科學公司 抗pd-1抗體類和使用彼等之方法
EP3247464B1 (en) 2015-01-21 2019-09-18 The Board of Trustees of the Leland Stanford Junior University Use of tlr agonist and anti-cd47 agent to enhance phagocytosis of cancer cells
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WO2017019767A1 (en) 2015-07-27 2017-02-02 Myosotis, Llc Inhibition of CXCL12 in Cancer Immunotherapy
EP3341015B2 (en) 2015-08-26 2023-12-27 The Board of Trustees of the Leland Stanford Junior University Enhanced depletion of targeted cells with cd47 blockade and an immune costimulatory agonist
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AU2016365829B2 (en) * 2015-12-11 2020-02-06 The Board Of Trustees Of The Leland Stanford Junior University Treatment of cancer with dual targeting of CD47 and EGFR
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KR102878970B1 (ko) 2016-08-03 2025-10-30 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 항-SIRPalpha 항체 요법의 대식세포 증진 효능에서 Fc 수용체 참여의 붕괴
WO2018031419A1 (en) 2016-08-12 2018-02-15 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for enhancing immunogenic cross-presentation of tumor antigens
EP3532497B1 (en) 2016-10-26 2024-07-24 The Board of Trustees of the Leland Stanford Junior University Modified immunoglobulin hinge regions to reduce hemagglutination
US11078272B2 (en) 2017-03-09 2021-08-03 The Board Of Trustees Of The Leland Stanford Junior University Treatment of pediatric brain tumors with targeting of CD47 pathway
PL3697819T3 (pl) 2017-10-18 2023-03-06 Forty Seven, Inc. Leczenie nowotworu złośliwego jajnika anty-cd47 i anty-pd-l1
SI4177270T1 (sl) 2017-10-18 2024-10-30 Forty Seven, Inc. Terapija za raka jajčnikov na osnovi sredstva proti cd47
WO2019241403A1 (en) 2018-06-13 2019-12-19 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for inducing phagocytosis
WO2020068431A1 (en) 2018-09-28 2020-04-02 The Board Of Trustees Of The Leland Stanford Junior University Analysis of polymorphisms in sirp-alpha for evaluating response to immunotherapy
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WO2020163692A1 (en) 2019-02-08 2020-08-13 The Board Of Trustees Of The Leland Stanford Junior University Treatment of cutaneous t cell lymphoma with targeting of cd47 pathway

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