JP2021500055A5 - - Google Patents
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- JP2021500055A5 JP2021500055A5 JP2020523378A JP2020523378A JP2021500055A5 JP 2021500055 A5 JP2021500055 A5 JP 2021500055A5 JP 2020523378 A JP2020523378 A JP 2020523378A JP 2020523378 A JP2020523378 A JP 2020523378A JP 2021500055 A5 JP2021500055 A5 JP 2021500055A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cell
- lymphoma
- antibody
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023124386A JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2024173232A JP2024177330A (ja) | 2017-10-27 | 2024-10-02 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762577922P | 2017-10-27 | 2017-10-27 | |
| US62/577,922 | 2017-10-27 | ||
| PCT/IB2018/058013 WO2019082020A1 (en) | 2017-10-27 | 2018-10-16 | ANTIBODIES AND CONJUGATES CD123-SPECIFIC ANTIBODIES AND USES THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023124386A Division JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500055A JP2021500055A (ja) | 2021-01-07 |
| JP2021500055A5 true JP2021500055A5 (enExample) | 2021-11-25 |
| JP7324749B2 JP7324749B2 (ja) | 2023-08-10 |
Family
ID=64109968
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020523378A Active JP7324749B2 (ja) | 2017-10-27 | 2018-10-16 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2023124386A Pending JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2024173232A Pending JP2024177330A (ja) | 2017-10-27 | 2024-10-02 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023124386A Pending JP2023139267A (ja) | 2017-10-27 | 2023-07-31 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
| JP2024173232A Pending JP2024177330A (ja) | 2017-10-27 | 2024-10-02 | Ｃｄ１２３に特異的な抗体および抗体－薬物コンジュゲートならびにその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US11613581B2 (enExample) |
| EP (1) | EP3700929A1 (enExample) |
| JP (3) | JP7324749B2 (enExample) |
| KR (1) | KR102363746B1 (enExample) |
| CN (2) | CN111556876B (enExample) |
| AU (1) | AU2018357221B2 (enExample) |
| BR (1) | BR112020008127A2 (enExample) |
| CA (2) | CA3205442A1 (enExample) |
| CO (1) | CO2020005347A2 (enExample) |
| IL (1) | IL274095B2 (enExample) |
| MX (1) | MX2020004381A (enExample) |
| PE (1) | PE20201255A1 (enExample) |
| PH (1) | PH12020550596A1 (enExample) |
| SA (1) | SA520411849B1 (enExample) |
| SG (1) | SG11202003246WA (enExample) |
| TW (2) | TWI718427B (enExample) |
| WO (1) | WO2019082020A1 (enExample) |
| ZA (1) | ZA202002207B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6521959B2 (ja) * | 2013-07-31 | 2019-05-29 | ライナット ニューロサイエンス コーポレイション | 操作されたポリペプチドコンジュゲート |
| MA47106A (fr) | 2016-12-21 | 2019-10-30 | Amgen Inc | Formulations d'anticorps anti-tnf alpha |
| CN111163809B (zh) | 2017-09-19 | 2024-07-02 | 保罗·谢勒学院 | 转谷氨酰胺酶缀合方法和接头 |
| CA3205442A1 (en) | 2017-10-27 | 2019-05-02 | Pfizer, Inc. | Antibodies and antibody-drug conjugates specific for cd123 and uses thereof |
| SE544015C2 (en) * | 2019-06-18 | 2021-11-02 | Tx Medic Ab | Allogenic car-t cell therapy |
| EP4114852A1 (en) * | 2020-03-03 | 2023-01-11 | Sutro Biopharma, Inc. | Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use |
| CN113563470B (zh) * | 2020-04-29 | 2023-02-10 | 广州昂科免疫生物技术有限公司 | 结合tigit抗原的抗体及其制备方法与应用 |
| MX2023004606A (es) | 2020-10-25 | 2023-05-08 | Araris Biotech Ag | Medios y metodos para producir conjugados de ligador-anticuerpo. |
| WO2022248835A1 (en) * | 2021-05-26 | 2022-12-01 | Oxford Biotherapeutics Ltd | Pharmaceutical combination comprising an anti-cd205 antibody and an immune checkpoint inhibitor |
| WO2023019393A1 (en) * | 2021-08-16 | 2023-02-23 | Utc Therapeutics (Shanghai) Co., Ltd. | Cd123-targetting antibodies, chimeric antigen receptors, and uses thereof |
| EP4422695A1 (en) * | 2021-10-25 | 2024-09-04 | Araris Biotech AG | Methods for producing antibody-linker conjugates |
| TW202423485A (zh) * | 2022-12-08 | 2024-06-16 | 美商伊繆諾金股份有限公司 | 包含抗cd123抗體-藥物結合物及抗cd47抗體之治療組合 |
| WO2025227361A1 (en) * | 2024-04-30 | 2025-11-06 | Wuxi Xdc (Shanghai) Co., Ltd. | Process for preparing a composition of antibody-drug conjugates (adcs) with high d4 content |
| CN118416247A (zh) * | 2024-04-30 | 2024-08-02 | 上海药明合联生物技术有限公司 | 用于制备具有高d4含量的抗体-药物缀合物（adc）组合物的方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4754065A (en) | 1984-12-18 | 1988-06-28 | Cetus Corporation | Precursor to nucleic acid probe |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5663149A (en) | 1994-12-13 | 1997-09-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| CA2364484A1 (en) | 1999-03-09 | 2000-09-14 | University Of Southern California | Method of promoting myocyte proliferation and myocardial tissue repair |
| US8163279B2 (en) | 2007-04-13 | 2012-04-24 | Stemline Therapeutics, Inc. | IL3Rα antibody conjugates and uses thereof |
| WO2010126066A1 (ja) * | 2009-04-27 | 2010-11-04 | 協和発酵キリン株式会社 | 血液腫瘍治療を目的とした抗IL-3Rα抗体 |
| WO2012059882A2 (en) | 2010-11-05 | 2012-05-10 | Rinat Neuroscience Corporation | Engineered polypeptide conjugates and methods for making thereof using transglutaminase |
| MX338353B (es) | 2011-04-20 | 2016-04-13 | Medimmune Llc | Anticuerpos y otras moleculas que se unen a b7 - h1 y pd - 1. |
| MX352738B (es) | 2011-11-17 | 2017-12-06 | Pfizer | Peptidos citotoxicos y conjugados de anticuerpo-farmaco de los mismos. |
| JP6521959B2 (ja) | 2013-07-31 | 2019-05-29 | ライナット ニューロサイエンス コーポレイション | 操作されたポリペプチドコンジュゲート |
| MX371147B (es) * | 2014-01-27 | 2020-01-20 | Pfizer | Agentes citotoxicos bifuncionales. |
| KR20160145790A (ko) | 2014-04-25 | 2016-12-20 | 리나트 뉴로사이언스 코프. | 약물이 고도로 로딩된 항체-약물 접합체 |
| HRP20200745T1 (hr) * | 2014-09-05 | 2020-08-07 | Janssen Pharmaceutica Nv | Agensi koji vezuju cd123 i njihove upotrebe |
| TN2017000275A1 (en) * | 2015-01-23 | 2018-10-19 | Sanofi Sa | Anti-cd3 antibodies, anti-cd123 antibodies and bispecific antibodies specifically binding to cd3 and/or cd123 |
| TW201709932A (zh) * | 2015-06-12 | 2017-03-16 | 西雅圖遺傳學公司 | Ｃｄ１２３抗體及其共軛物 |
| CN107921146A (zh) * | 2015-06-23 | 2018-04-17 | 拜耳医药股份有限公司 | 纺锤体驱动蛋白(ksp)抑制剂与抗‑cd123的抗体的抗体药物缀合物(adc) |
| BR112017027254A2 (pt) * | 2015-06-29 | 2019-05-14 | Immunogen, Inc. | anticorpos anti-cd123 e conjugados e derivados dos mesmos |
| US11976121B2 (en) * | 2017-07-20 | 2024-05-07 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | CD123-binding chimeric antigen receptors |
| CA3205442A1 (en) | 2017-10-27 | 2019-05-02 | Pfizer, Inc. | Antibodies and antibody-drug conjugates specific for cd123 and uses thereof |
-
2018
- 2018-10-16 CA CA3205442A patent/CA3205442A1/en active Pending
- 2018-10-16 AU AU2018357221A patent/AU2018357221B2/en active Active
- 2018-10-16 KR KR1020207014653A patent/KR102363746B1/ko active Active
- 2018-10-16 EP EP18797140.3A patent/EP3700929A1/en active Pending
- 2018-10-16 SG SG11202003246WA patent/SG11202003246WA/en unknown
- 2018-10-16 PE PE2020000682A patent/PE20201255A1/es unknown
- 2018-10-16 IL IL274095A patent/IL274095B2/en unknown
- 2018-10-16 CN CN201880069901.2A patent/CN111556876B/zh active Active
- 2018-10-16 CA CA3079788A patent/CA3079788C/en active Active
- 2018-10-16 US US16/758,124 patent/US11613581B2/en active Active
- 2018-10-16 MX MX2020004381A patent/MX2020004381A/es unknown
- 2018-10-16 JP JP2020523378A patent/JP7324749B2/ja active Active
- 2018-10-16 WO PCT/IB2018/058013 patent/WO2019082020A1/en not_active Ceased
- 2018-10-16 CN CN202411219753.1A patent/CN119119272A/zh active Pending
- 2018-10-16 BR BR112020008127-2A patent/BR112020008127A2/pt unknown
- 2018-10-24 TW TW107137519A patent/TWI718427B/zh active
- 2018-10-24 TW TW110103347A patent/TWI793513B/zh active
-
2020
- 2020-04-27 SA SA520411849A patent/SA520411849B1/ar unknown
- 2020-04-28 CO CONC2020/0005347A patent/CO2020005347A2/es unknown
- 2020-04-29 PH PH12020550596A patent/PH12020550596A1/en unknown
- 2020-05-04 ZA ZA2020/02207A patent/ZA202002207B/en unknown
-
2023
- 2023-03-08 US US18/180,704 patent/US20230357417A1/en not_active Abandoned
- 2023-07-31 JP JP2023124386A patent/JP2023139267A/ja active Pending
-
2024
- 2024-10-02 JP JP2024173232A patent/JP2024177330A/ja active Pending
- 2024-12-03 US US18/967,173 patent/US20250154270A1/en active Pending
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