JP2021184731A5 - - Google Patents
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- Publication number
- JP2021184731A5 JP2021184731A5 JP2021128846A JP2021128846A JP2021184731A5 JP 2021184731 A5 JP2021184731 A5 JP 2021184731A5 JP 2021128846 A JP2021128846 A JP 2021128846A JP 2021128846 A JP2021128846 A JP 2021128846A JP 2021184731 A5 JP2021184731 A5 JP 2021184731A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antigen
- antibody
- binding
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462010117P | 2014-06-10 | 2014-06-10 | |
| US62/010,117 | 2014-06-10 | ||
| EP15305078.6 | 2015-01-23 | ||
| EP15305078.6A EP2955196A1 (en) | 2014-06-10 | 2015-01-23 | Antibodies directed against CD127 |
| JP2017517406A JP7324565B2 (ja) | 2014-06-10 | 2015-06-10 | Ｃｄ１２７に対する抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517406A Division JP7324565B2 (ja) | 2014-06-10 | 2015-06-10 | Ｃｄ１２７に対する抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021184731A JP2021184731A (ja) | 2021-12-09 |
| JP2021184731A5 true JP2021184731A5 (Direct) | 2022-03-03 |
Family
ID=52434718
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517406A Active JP7324565B2 (ja) | 2014-06-10 | 2015-06-10 | Ｃｄ１２７に対する抗体 |
| JP2021128846A Pending JP2021184731A (ja) | 2014-06-10 | 2021-08-05 | Ｃｄ１２７に対する抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517406A Active JP7324565B2 (ja) | 2014-06-10 | 2015-06-10 | Ｃｄ１２７に対する抗体 |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US10428152B2 (Direct) |
| EP (2) | EP2955196A1 (Direct) |
| JP (2) | JP7324565B2 (Direct) |
| KR (1) | KR102612930B1 (Direct) |
| CN (1) | CN106715471B (Direct) |
| AP (1) | AP2016009599A0 (Direct) |
| AU (1) | AU2015273532C1 (Direct) |
| BR (1) | BR112016028755B1 (Direct) |
| CA (1) | CA2950823A1 (Direct) |
| CL (1) | CL2016003172A1 (Direct) |
| CR (1) | CR20160576A (Direct) |
| EA (1) | EA039303B1 (Direct) |
| HK (1) | HK1231487A1 (Direct) |
| IL (1) | IL249449B (Direct) |
| MA (1) | MA40202A (Direct) |
| MX (1) | MX376066B (Direct) |
| MY (1) | MY190889A (Direct) |
| NZ (1) | NZ726932A (Direct) |
| PE (1) | PE20170324A1 (Direct) |
| PH (1) | PH12016502445A1 (Direct) |
| RU (1) | RU2734076C2 (Direct) |
| SA (1) | SA516380455B1 (Direct) |
| SG (1) | SG11201610036PA (Direct) |
| TN (1) | TN2016000528A1 (Direct) |
| UA (1) | UA125366C2 (Direct) |
| WO (1) | WO2015189302A1 (Direct) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| EP2955196A1 (en) * | 2014-06-10 | 2015-12-16 | Effimune | Antibodies directed against CD127 |
| EP3277713B1 (en) | 2015-03-31 | 2025-09-10 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
| CA2981098A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Peptide construct having a protease-cleavable linker |
| MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
| EP3405491A1 (en) | 2016-01-21 | 2018-11-28 | VHsquared Limited | Polypeptides |
| BR112018067479A2 (pt) * | 2016-02-29 | 2019-01-15 | Ose Immunotherapeutics | anticorpo, fragmento de ligação ao antígeno de um anticorpo, molécula quimérica, receptor de antígeno quimérico, polinucleotídeo, célula, métodos para preparação de receptor de antígeno quimérico, para fabricação de um anticorpo e para determinação da presença de células cd127+, composição farmacêutica, meio terapêutico de combinação, método de diagnóstico, e, uso de um anticorpo anti-cd127 ou um fragmento de ligação ao antígeno do mesmo |
| CA3042582C (en) * | 2016-12-09 | 2023-05-23 | Ose Immunotherapeutics | Antibodies and polypeptides directed against cd127 |
| US12258577B2 (en) | 2017-08-29 | 2025-03-25 | Ose Immunotherapeutics | Method effector cells using anti-CD127 antibodies for applications in cell therapy |
| CN110117325B (zh) * | 2018-03-09 | 2023-06-20 | 重庆市畜牧科学院 | 一种猪cd127多肽及其编码基因和应用 |
| CN118894938A (zh) | 2019-01-22 | 2024-11-05 | 百时美施贵宝公司 | 抗IL-7Rα亚基的抗体及其用途 |
| JOP20210298A1 (ar) | 2019-05-14 | 2023-01-30 | Provention Bio Inc | طرق وتركيبات للوقاية من مرض السكري من النوع الأول |
| JP7702363B2 (ja) | 2019-06-21 | 2025-07-03 | ソリッソ ファーマシューティカルズ，インク． | 組成物 |
| WO2020254826A1 (en) | 2019-06-21 | 2020-12-24 | Vhsquared Limited | Polypeptides |
| CN114466864B (zh) | 2019-06-21 | 2024-12-27 | 索瑞索制药公司 | 多肽 |
| CN110894237B (zh) * | 2019-12-05 | 2021-08-03 | 山东省分析测试中心 | 抗cd127的抗体、分泌该抗体的细胞株及其制备方法和应用 |
| CA3181394A1 (en) * | 2020-04-27 | 2021-11-04 | Memorial Sloan-Kettering Cancer Center | Chimeric antigen receptors targeting cd127 and use thereof |
| WO2021252917A2 (en) | 2020-06-11 | 2021-12-16 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| US20220389104A1 (en) * | 2021-05-28 | 2022-12-08 | Ose Immunotherapeutics | Method for Treating CD127-Positive Cancers by Administering an Anti-CD127 Agent |
| JP2025518164A (ja) | 2022-05-30 | 2025-06-12 | オセ イムノセラピューティクス | Ｉｌ７ｒモジュレーター活性のバイオマーカー |
| CN115925955B (zh) * | 2022-12-30 | 2025-09-26 | 浙江正熙生物技术有限公司 | 一种抗cd127抗体及其制备方法和应用 |
| CN121002069A (zh) | 2023-01-06 | 2025-11-21 | 泰温治疗私人有限公司 | 抗原结合分子 |
| EP4455308A1 (en) | 2023-04-24 | 2024-10-30 | Les Laboratoires Servier | Il-7r gene signatures |
| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| WO2025089399A1 (ja) * | 2023-10-26 | 2025-05-01 | 国立研究開発法人国立がん研究センター | インターロイキン７受容体（ｉｌ－７ｒ）に対する抗体および当該抗体を含む抗体薬物コンジュゲート（ａｄｃ） |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025202213A1 (en) | 2024-03-26 | 2025-10-02 | Institut National de la Santé et de la Recherche Médicale | Lipid nanoparticle loaded with antitumoral agent and functionnalized to target immosuppressive cells |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| CN118638236B (zh) * | 2024-07-09 | 2025-03-14 | 武汉爱博泰克生物科技有限公司 | 抗人cd127蛋白的抗体、抗体偶联物及其应用 |
| WO2026022216A1 (en) | 2024-07-23 | 2026-01-29 | Ose Immunotherapeutics | Uses of anti-cd127 antibodies in the treatment of inflammatory bowel diseases |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| US9012134B2 (en) | 2006-05-31 | 2015-04-21 | The Regents Of The University Of California | CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ Tregs |
| ATE542830T1 (de) | 2006-12-04 | 2012-02-15 | Pasteur Institut | Als gerüst verwendeter ob-fold zur entwicklung neuer spezifischer bindemittel |
| TW201018482A (en) * | 2008-08-08 | 2010-05-16 | Glaxo Wellcome Mfg Pte Ltd | Novel treatment |
| WO2010085643A1 (en) | 2009-01-22 | 2010-07-29 | University Of Miami | Targeting il-7 signaling as a therapy for multiple sclerosis and other il-7 signaling dependent disorders |
| WO2011094259A2 (en) * | 2010-01-28 | 2011-08-04 | Glaxo Group Limited | Cd127 binding proteins |
| US8298535B2 (en) | 2010-02-24 | 2012-10-30 | Rinat Neuroscience Corp. | Anti-IL-7 receptor antibodies |
| EP2583980A1 (en) | 2011-10-19 | 2013-04-24 | Effimune | Antibodies directed against the alpha chain of IL7 receptor - their use for the preparation of drug candidates |
| EP2955196A1 (en) * | 2014-06-10 | 2015-12-16 | Effimune | Antibodies directed against CD127 |
| BR112018067479A2 (pt) | 2016-02-29 | 2019-01-15 | Ose Immunotherapeutics | anticorpo, fragmento de ligação ao antígeno de um anticorpo, molécula quimérica, receptor de antígeno quimérico, polinucleotídeo, célula, métodos para preparação de receptor de antígeno quimérico, para fabricação de um anticorpo e para determinação da presença de células cd127+, composição farmacêutica, meio terapêutico de combinação, método de diagnóstico, e, uso de um anticorpo anti-cd127 ou um fragmento de ligação ao antígeno do mesmo |
-
2015
- 2015-01-23 EP EP15305078.6A patent/EP2955196A1/en not_active Withdrawn
- 2015-06-10 TN TN2016000528A patent/TN2016000528A1/en unknown
- 2015-06-10 UA UAA201613258A patent/UA125366C2/uk unknown
- 2015-06-10 WO PCT/EP2015/062993 patent/WO2015189302A1/en not_active Ceased
- 2015-06-10 AU AU2015273532A patent/AU2015273532C1/en active Active
- 2015-06-10 JP JP2017517406A patent/JP7324565B2/ja active Active
- 2015-06-10 EA EA201692460A patent/EA039303B1/ru unknown
- 2015-06-10 BR BR112016028755-0A patent/BR112016028755B1/pt active IP Right Grant
- 2015-06-10 NZ NZ726932A patent/NZ726932A/en unknown
- 2015-06-10 SG SG11201610036PA patent/SG11201610036PA/en unknown
- 2015-06-10 HK HK17104912.8A patent/HK1231487A1/zh unknown
- 2015-06-10 MA MA040202A patent/MA40202A/fr unknown
- 2015-06-10 EP EP15727989.4A patent/EP3155014A1/en active Pending
- 2015-06-10 US US15/317,355 patent/US10428152B2/en active Active
- 2015-06-10 KR KR1020177000724A patent/KR102612930B1/ko active Active
- 2015-06-10 CA CA2950823A patent/CA2950823A1/en active Pending
- 2015-06-10 MY MYPI2016002094A patent/MY190889A/en unknown
- 2015-06-10 AP AP2016009599A patent/AP2016009599A0/en unknown
- 2015-06-10 CR CR20160576A patent/CR20160576A/es unknown
- 2015-06-10 RU RU2016151265A patent/RU2734076C2/ru active
- 2015-06-10 CN CN201580043066.1A patent/CN106715471B/zh active Active
- 2015-06-10 MX MX2016016236A patent/MX376066B/es active IP Right Grant
- 2015-06-10 PE PE2016002699A patent/PE20170324A1/es unknown
-
2016
- 2016-12-06 PH PH12016502445A patent/PH12016502445A1/en unknown
- 2016-12-07 IL IL249449A patent/IL249449B/en active IP Right Grant
- 2016-12-08 SA SA516380455A patent/SA516380455B1/ar unknown
- 2016-12-09 CL CL2016003172A patent/CL2016003172A1/es unknown
-
2019
- 2019-08-05 US US16/532,000 patent/US11440964B2/en active Active
-
2021
- 2021-08-05 JP JP2021128846A patent/JP2021184731A/ja active Pending
-
2022
- 2022-09-09 US US17/941,885 patent/US12371502B2/en active Active
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