|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4801687A
(en)
|
1986-10-27 |
1989-01-31 |
Bioprobe International, Inc. |
Monoclonal antibody purification process using protein A
|
|
FI884924A7
(fi)
|
1987-10-28 |
1989-04-29 |
Oncogen |
Yhdistelmä-DNA-tekniikalla tuotettuja ihmisimmunoglobuliineja
|
|
US5476996A
(en)
|
1988-06-14 |
1995-12-19 |
Lidak Pharmaceuticals |
Human immune system in non-human animal
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5151504A
(en)
|
1989-11-17 |
1992-09-29 |
E. R. Squibb & Sons, Inc. |
Method for purification of monoclonal antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
EP1690934A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
ATE300615T1
(de)
|
1990-08-29 |
2005-08-15 |
Genpharm Int |
Transgene mäuse fähig zur produktion heterologer antikörper
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
GB9022543D0
(en)
|
1990-10-17 |
1990-11-28 |
Wellcome Found |
Antibody production
|
|
CA2111858A1
(en)
|
1991-07-15 |
1993-02-04 |
James S. Crowe |
Production of antibodies
|
|
ES2341666T3
(es)
|
1991-12-02 |
2010-06-24 |
Medimmune Limited |
Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
|
|
SE9400088D0
(sv)
|
1994-01-14 |
1994-01-14 |
Kabi Pharmacia Ab |
Bacterial receptor structures
|
|
FR2762840B1
(fr)
*
|
1997-05-02 |
1999-08-13 |
Corning Sa |
Compositions photochromiques, composes photochromes, matrices (co)polymeres et produits finis les incorporant
|
|
DE19742706B4
(de)
|
1997-09-26 |
2013-07-25 |
Pieris Proteolab Ag |
Lipocalinmuteine
|
|
GB9815909D0
(en)
|
1998-07-21 |
1998-09-16 |
Btg Int Ltd |
Antibody preparation
|
|
US6818418B1
(en)
|
1998-12-10 |
2004-11-16 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
|
CN100457914C
(zh)
|
1999-04-15 |
2009-02-04 |
荷兰克鲁塞尔公司 |
用编码腺病毒e1蛋白的序列在人体细胞中生产重组蛋白
|
|
SE9901379D0
(sv)
|
1999-04-19 |
1999-04-19 |
Pharmacia & Upjohn Ab |
Receptor structures
|
|
DE19932688B4
(de)
|
1999-07-13 |
2009-10-08 |
Scil Proteins Gmbh |
Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
|
|
CN1487996B
(zh)
|
2000-11-30 |
2010-06-16 |
米德列斯公司 |
用于生产人类抗体的转基因转染色体啮齿动物
|
|
WO2003011911A1
(fr)
|
2001-07-31 |
2003-02-13 |
Ono Pharmaceutical Co., Ltd. |
Substance specifique pour pd-1
|
|
GB2380127A
(en)
|
2001-09-26 |
2003-04-02 |
Isis Innovation |
Treatment of chronic joint inflammation
|
|
NZ537277A
(en)
|
2002-07-18 |
2008-04-30 |
Crucell Holland Bv |
Recombinant production of mixtures of antibodies
|
|
CN1753912B
(zh)
|
2002-12-23 |
2011-11-02 |
惠氏公司 |
抗pd-1抗体及其用途
|
|
US7563869B2
(en)
*
|
2003-01-23 |
2009-07-21 |
Ono Pharmaceutical Co., Ltd. |
Substance specific to human PD-1
|
|
KR100515798B1
(ko)
|
2003-02-10 |
2005-09-21 |
한국과학기술원 |
입 벌림 정도와 얼굴방향 인식방법 및 얼굴 제스처를이용한 로봇 구동방법
|
|
DE10324447A1
(de)
|
2003-05-28 |
2004-12-30 |
Scil Proteins Gmbh |
Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin
|
|
JP5139800B2
(ja)
|
2004-06-03 |
2013-02-06 |
ノビミューン エスアー |
抗ｃｄ３抗体およびその使用方法
|
|
RU2494107C2
(ru)
|
2005-05-09 |
2013-09-27 |
Оно Фармасьютикал Ко., Лтд. |
Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
|
|
AR057807A1
(es)
|
2005-09-12 |
2007-12-19 |
Novimmune Sa |
Formulaciones de anticuerpo anti-cd3
|
|
AU2006301492B2
(en)
|
2005-10-11 |
2011-06-09 |
Amgen Research (Munich) Gmbh |
Compositions comprising cross-species-specific antibodies and uses thereof
|
|
HRP20131167T1
(hr)
|
2007-06-18 |
2014-01-03 |
Merck Sharp & Dohme B.V. |
Antitijela za humani receptor programirane smrti pd-1
|
|
PL3456190T3
(pl)
*
|
2008-06-27 |
2022-06-06 |
Merus N.V. |
Wytwarzające przeciwciała transgeniczne zwierzę z gatunku myszy
|
|
JP5794917B2
(ja)
|
2008-09-12 |
2015-10-14 |
アイシス・イノベーション・リミテッドＩｓｉｓ Ｉｎｎｏｖａｔｉｏｎｌｉｍｉｔｅｄ |
Ｐｄ−１特異抗体およびその使用
|
|
US8927697B2
(en)
|
2008-09-12 |
2015-01-06 |
Isis Innovation Limited |
PD-1 specific antibodies and uses thereof
|
|
KR101814408B1
(ko)
|
2008-09-26 |
2018-01-04 |
다나-파버 캔서 인스티튜트 인크. |
인간 항-ｐｄ-１, ｐｄ-ｌ１, 및 ｐｄ-ｌ2 항체 및 그의 용도
|
|
NZ591087A
(en)
|
2008-10-01 |
2012-08-31 |
Micromet Ag |
Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
|
|
JP6126782B2
(ja)
|
2008-10-01 |
2017-05-10 |
アムゲン リサーチ （ミュンヘン） ゲーエムベーハー |
異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体
|
|
PT3330293T
(pt)
|
2008-11-07 |
2019-10-18 |
Amgen Res Munich Gmbh |
Tratamento da leucemia linfoblástica aguda pediátrica com anticorpos biespecíficos contra cd3xcd19
|
|
MX2012002428A
(es)
|
2009-08-27 |
2012-09-12 |
Covagen Ag |
Compuestos de union il-17 y usos medicos de los mismos.
|
|
TW201134488A
(en)
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
|
CN102892786B
(zh)
|
2010-03-11 |
2016-03-16 |
Ucb医药有限公司 |
Pd-1抗体
|
|
CN102219856B
(zh)
|
2011-05-18 |
2013-03-27 |
哈尔滨医科大学 |
一种抗血管内皮细胞生长因子受体2/抗cd3双特异单链抗体
|
|
EP2742953B1
(en)
|
2011-08-11 |
2021-09-22 |
ONO Pharmaceutical Co., Ltd. |
Therapeutic agent for autoimmune diseases comprising pd-1 agonist
|
|
KR20130022091A
(ko)
|
2011-08-24 |
2013-03-06 |
주식회사 케이티 |
클라우드 컴퓨팅 서버 시스템의 가상머신 제어 장치 및 방법
|
|
SI2838917T1
(sl)
|
2012-04-20 |
2019-11-29 |
Merus Nv |
Postopki in sredstva za produkcijo heterodimernih IG-podobnih molekul
|
|
EP2892924B1
(en)
|
2012-06-14 |
2020-11-25 |
Therapix Biosciences Ltd. |
Humanized antibodies to cluster of differentiation 3 (cd3)
|
|
AU2013302696B9
(en)
|
2012-08-14 |
2018-08-09 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
|
EP3470431A1
(en)
|
2012-09-27 |
2019-04-17 |
Merus N.V. |
Bispecific igg antibodies as t cell engagers
|
|
WO2014151438A1
(en)
|
2013-03-15 |
2014-09-25 |
Emergent Product Development Seattle, Llc |
Multispecific anti-cd37 antibodies and related compositions and methods
|
|
CN105431449B
(zh)
|
2013-04-05 |
2021-08-24 |
港大科桥有限公司 |
新的pd1同种型及其用于加强免疫应答的用途
|
|
CN104098698B
(zh)
|
2013-04-08 |
2019-04-05 |
中国人民解放军第二军医大学 |
一种抗cd3抗体及其制法和应用
|
|
KR20210094669A
(ko)
*
|
2013-04-29 |
2021-07-29 |
에프. 호프만-라 로슈 아게 |
인간 fcrn-결합 변형된 항체 및 사용 방법
|
|
JP6742903B2
(ja)
|
2013-05-02 |
2020-08-19 |
アナプティスバイオ インコーポレイティッド |
プログラム死−１（ｐｄ−１）に対する抗体
|
|
US9676853B2
(en)
|
2013-05-31 |
2017-06-13 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-1
|
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
|
US10077305B2
(en)
|
2013-09-10 |
2018-09-18 |
Medimmune Limited |
Antibodies against PD-1 and uses thereof
|
|
EA034666B1
(ru)
|
2013-09-13 |
2020-03-04 |
Бейджин Свитзерланд Гмбх |
Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
|
|
MY184154A
(en)
|
2013-12-12 |
2021-03-23 |
Shanghai hengrui pharmaceutical co ltd |
Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
|
UA129760C2
(uk)
|
2013-12-17 |
2025-07-30 |
Дженентек, Інк. |
Анти-cd3 антитіло та спосіб його застосування
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對ｐｄ-１的人類抗體
|
|
TWI754319B
(zh)
|
2014-03-19 |
2022-02-01 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
|
KR102524920B1
(ko)
|
2014-07-22 |
2023-04-25 |
아폴로믹스 인코포레이티드 |
항-pd-1 항체
|
|
JP7020909B2
(ja)
|
2014-07-25 |
2022-02-16 |
シトムクス セラピューティクス，インコーポレイティド |
抗－ｃｄ３抗体、活性化可能抗－ｃｄ３抗体、多重特異的抗－ｃｄ３抗体、多重特異的活性化可能抗－ｃｄ３抗体、及びそれらの使用方法
|
|
CN105330740B
(zh)
|
2014-07-30 |
2018-08-17 |
珠海市丽珠单抗生物技术有限公司 |
抗pd-1抗体及其应用
|
|
ES2743809T3
(es)
|
2014-07-31 |
2020-02-20 |
Amgen Res Munich Gmbh |
Constructos de anticuerpo monocatenarios biespecificos específicos de especies cruzadas optimizados
|
|
GB201419084D0
(en)
|
2014-10-27 |
2014-12-10 |
Agency Science Tech & Res |
Anti-PD-1 antibodies
|
|
EP3218409A2
(en)
|
2014-11-11 |
2017-09-20 |
Sutro Biopharma, Inc. |
Anti-pd-1 antibodies, compositions comprising anti-pd-1 antibodies and methods of using anti-pd-1 antibodies
|
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗ｐｄ－１抗體類和使用彼等之方法
|
|
EP3916017A1
(en)
|
2014-12-22 |
2021-12-01 |
PD-1 Acquisition Group, LLC |
Anti-pd-1 antibodies
|
|
EA201791768A1
(ru)
|
2015-02-06 |
2018-07-31 |
КАДМОН КОРПОРЕЙШН, ЭлЭлСи |
Иммуномодулирующие агенты
|
|
EP3778640A1
(en)
|
2015-05-01 |
2021-02-17 |
Genentech, Inc. |
Masked anti-cd3 antibodies and methods of use
|
|
CN105061597B
(zh)
|
2015-06-09 |
2016-04-27 |
北京东方百泰生物科技有限公司 |
一种抗pd-1的单克隆抗体及其获得方法
|
|
HK1254803A1
(zh)
|
2015-06-23 |
2019-07-26 |
Memorial Sloan Kettering Cancer Center |
新型pd -1的免疫调节剂
|
|
SI3115376T1
(sl)
*
|
2015-07-10 |
2018-12-31 |
Merus N.V. |
Humana protitelesa, ki vežejo CD3
|
|
CN114591433A
(zh)
|
2015-07-13 |
2022-06-07 |
西托姆克斯治疗公司 |
抗pd-1抗体、可活化抗pd-1抗体及其使用方法
|
|
CN106349391A
(zh)
|
2015-07-17 |
2017-01-25 |
中国科学院深圳先进技术研究院 |
Hbv特异性双靶向抗体及其制备方法和应用、含该双靶向抗体表达盒的微环dna及应用
|
|
CN106699888B
(zh)
|
2015-07-28 |
2020-11-06 |
上海昀怡健康科技发展有限公司 |
一种pd-1抗体及其制备方法和应用
|
|
WO2017019846A1
(en)
|
2015-07-30 |
2017-02-02 |
Macrogenics, Inc. |
Pd-1-binding molecules and methods use thereof
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究（慕尼黑）公司 |
Ｃｄ７０及ｃｄ３抗體構築體
|
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究（慕尼黑）公司 |
Ｄｌｌ３及ｃｄ３抗體構築體
|
|
WO2017024465A1
(en)
|
2015-08-10 |
2017-02-16 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
|
KR102055396B1
(ko)
|
2015-08-11 |
2019-12-12 |
우시 바이올로직스 (케이만) 인코포레이티드 |
신규한 항-pd-1 항체
|
|
WO2017024515A1
(en)
|
2015-08-11 |
2017-02-16 |
Wuxi Biologics (Cayman) Inc. |
Novel anti-pd-1 antibodies
|
|
CN114605548A
(zh)
|
2015-09-01 |
2022-06-10 |
艾吉纳斯公司 |
抗-pd-1抗体及其使用方法
|
|
LT3353212T
(lt)
|
2015-09-23 |
2021-12-27 |
Regeneron Pharmaceuticals, Inc. |
Optimizuoti anti-cd3 bispecifiniai antikūnai ir jų naudojimas
|
|
US10981991B2
(en)
|
2015-09-29 |
2021-04-20 |
Shanghai Zhangjiang Biotechnology Co., Ltd. |
PD-1 antibodies and uses thereof
|
|
EA201890790A1
(ru)
|
2015-09-29 |
2018-10-31 |
Селджин Корпорейшн |
Связывающие pd-1 белки и способы их применения
|
|
CR20180151A
(es)
|
2015-10-02 |
2018-05-25 |
Hoffmann La Roche |
Antcuierpos anti-pd1 y métodos de uso
|
|
PL3368572T3
(pl)
|
2015-10-02 |
2022-09-12 |
Symphogen A/S |
Przeciwciała anty-PD-1 oraz kompozycje
|
|
US10752686B2
(en)
|
2015-10-30 |
2020-08-25 |
Zonhon Biopharma Institute Inc. |
Bispecific antibody binding to human CD26 and human CD3, production method therefor and use thereof
|
|
EP3370768B9
(en)
|
2015-11-03 |
2022-03-16 |
Janssen Biotech, Inc. |
Antibodies specifically binding pd-1 and their uses
|
|
CN106699889A
(zh)
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技（上海）有限公司 |
抗pd-1抗体及其治疗用途
|
|
CN106810611A
(zh)
|
2015-11-30 |
2017-06-09 |
中国科学院深圳先进技术研究院 |
抗cMet和CD3特异性双靶向抗体及其制备方法和应用、含该双靶向抗体表达盒的微环DNA及应用
|
|
KR102809728B1
(ko)
|
2015-12-02 |
2025-05-21 |
주식회사 에스티큐브 |
글리코실화된 pd-1에 대해 특이적인 항체 및 이의 사용 방법
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
US20180291114A1
(en)
|
2015-12-17 |
2018-10-11 |
University Of Maryland, Baltimore County |
Recombinant bi-specific polypeptide for coordinately activating tumor-reactive t-cells and neutralizing immune suppression
|
|
JP7126941B2
(ja)
|
2015-12-22 |
2022-08-29 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
がんを治療するための抗ｐｄ－１抗体と二重特異性抗ｃｄ２０／抗ｃｄ３抗体の組合せ
|
|
CN105669864B
(zh)
|
2015-12-23 |
2018-10-16 |
杭州尚健生物技术有限公司 |
抗人程序性死亡受体1抗体及其制备方法和用途
|
|
US10759859B2
(en)
|
2016-01-14 |
2020-09-01 |
Bps Bioscience, Inc. |
Anti-PD-1 antibodies and uses thereof
|
|
WO2017125815A2
(en)
|
2016-01-22 |
2017-07-27 |
MabQuest SA |
Immunological reagents
|
|
WO2017132827A1
(en)
|
2016-02-02 |
2017-08-10 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
|
EP3411404B1
(en)
|
2016-02-03 |
2022-11-09 |
Amgen Research (Munich) GmbH |
Psma and cd3 bispecific t cell engaging antibody constructs
|
|
CN107286242B
(zh)
|
2016-04-01 |
2019-03-22 |
中山康方生物医药有限公司 |
抗pd-1的单克隆抗体
|
|
AU2017266298B2
(en)
|
2016-05-18 |
2024-01-04 |
Boehringer Ingelheim International Gmbh |
Anti PD-1 and anti-LAG3 antibodies for cancer treatment
|
|
CN106008714B
(zh)
|
2016-05-24 |
2019-03-15 |
瑞阳(苏州)生物科技有限公司 |
抗人pd-1人源化单克隆抗体及其应用
|
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
|
CN106084049A
(zh)
|
2016-06-17 |
2016-11-09 |
中山大学 |
抗cd3单域抗体
|
|
CN106146661A
(zh)
|
2016-06-17 |
2016-11-23 |
中山大学 |
抗cd3单域抗体
|
|
CN106084046A
(zh)
|
2016-06-17 |
2016-11-09 |
中山大学 |
抗cd3单域抗体
|
|
NL2017267B1
(en)
|
2016-07-29 |
2018-02-01 |
Aduro Biotech Holdings Europe B V |
Anti-pd-1 antibodies
|
|
WO2018026248A1
(ko)
|
2016-08-05 |
2018-02-08 |
주식회사 와이바이오로직스 |
프로그램화된 세포 사멸 단백질(pd-1)에 대한 신규 항체 및 이의 용도
|
|
JP6960635B2
(ja)
|
2016-08-15 |
2021-11-05 |
国立大学法人北海道大学 |
抗ｐｄ−１抗体
|
|
CN106977602B
(zh)
|
2016-08-23 |
2018-09-25 |
中山康方生物医药有限公司 |
一种抗pd1单克隆抗体、其药物组合物及其用途
|
|
KR102561356B1
(ko)
|
2016-09-14 |
2023-08-03 |
애브비 바이오테라퓨틱스 인크. |
항-pd-1 항체 및 이의 용도
|
|
WO2018052818A1
(en)
|
2016-09-16 |
2018-03-22 |
Henlix, Inc. |
Anti-pd-1 antibodies
|
|
BR112018013653B1
(pt)
|
2016-10-15 |
2020-12-15 |
Innovent Biologics (Suzhou) Co., Ltd |
Anticorpos anti-pd-1, processo para produção do mesmo e uso dos anticorpos
|
|
CA3041684C
(en)
|
2016-11-01 |
2023-09-26 |
Anaptysbio, Inc. |
Antibodies directed against programmed death- 1 (pd-1)
|
|
HUE057559T2
(hu)
|
2016-11-02 |
2022-06-28 |
Jounce Therapeutics Inc |
PD-1 elleni antitestek és alkalmazásaik
|
|
EA201990978A1
(ru)
|
2016-11-08 |
2019-12-30 |
Актиджен Лтд |
Антитела против pd-1
|
|
TWI780083B
(zh)
|
2016-11-18 |
2022-10-11 |
丹麥商賽門弗鎮公司 |
抗pd-1抗體及組成物
|
|
WO2018114754A1
(en)
|
2016-12-19 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Combination therapy with targeted 4-1bb (cd137) agonists
|
|
CN106519034B
(zh)
|
2016-12-22 |
2020-09-18 |
鲁南制药集团股份有限公司 |
抗pd-1抗体及其用途
|
|
RU2768404C2
(ru)
|
2016-12-23 |
2022-03-24 |
Ремд Биотерапьютикс, Инк. |
Иммунотерапия с применением антител, связывающих белок 1 программируемой смерти клеток (pd-1)
|
|
EP3589652B1
(en)
|
2017-03-04 |
2024-12-25 |
Xiangtan Tenghua Bioscience |
Recombinant antibodies to programmed death 1 (pd-1) and uses therefor
|
|
CN106939049B
(zh)
|
2017-04-20 |
2019-10-01 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用
|
|
CN110198739B
(zh)
|
2017-05-16 |
2023-04-04 |
江苏恒瑞医药股份有限公司 |
一种pd-l1抗体药物组合物及其用途
|
|
WO2018217227A1
(en)
|
2017-05-24 |
2018-11-29 |
Immunomedics, Inc. |
Novel anti-pd-1 checkpoint inhibitor antibodies that block binding of pd-l1 to pd-1
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
KR20200041834A
(ko)
|
2017-06-01 |
2020-04-22 |
젠코어 인코포레이티드 |
Cd123 및 cd3에 결합하는 이중특이성 항체
|
|
CR20190550A
(es)
|
2017-06-05 |
2020-04-05 |
Janssen Biotech Inc |
Anticuerpos que se unen específicamente a pd-1 y métodos de uso
|
|
WO2019005635A2
(en)
|
2017-06-25 |
2019-01-03 |
Systimmune, Inc. |
ANTI-PD-1 ANTIBODIES AND METHODS OF PREPARATION AND USE
|
|
CN118909118A
(zh)
|
2017-09-07 |
2024-11-08 |
奥古斯塔大学研究所公司 |
程序性细胞死亡蛋白1抗体
|
|
EP3693013A4
(en)
*
|
2017-10-06 |
2021-06-30 |
Ono Pharmaceutical Co., Ltd. |
BISPECIFIC ANTIBODY
|
|
CN107501412A
(zh)
|
2017-10-11 |
2017-12-22 |
深圳精准医疗科技有限公司 |
突变型双特异性抗体及其应用
|
|
TWI849895B
(zh)
*
|
2018-02-09 |
2024-07-21 |
日商小野藥品工業股份有限公司 |
雙特異性抗體
|
|
TWI862565B
(zh)
*
|
2019-04-04 |
2024-11-21 |
日商小野藥品工業股份有限公司 |
雙特異性抗體
|