JP2021075563A5 - - Google Patents
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- JP2021075563A5 JP2021075563A5 JP2021020446A JP2021020446A JP2021075563A5 JP 2021075563 A5 JP2021075563 A5 JP 2021075563A5 JP 2021020446 A JP2021020446 A JP 2021020446A JP 2021020446 A JP2021020446 A JP 2021020446A JP 2021075563 A5 JP2021075563 A5 JP 2021075563A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- oxo
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- fibrosis
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 206010016654 Fibrosis Diseases 0.000 claims 5
- 230000004761 fibrosis Effects 0.000 claims 5
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 claims 2
- JEGJFECBWADGJX-RHDCIPCHSA-N (8Z,11Z,13E)-15-oxoicosa-8,11,13-trienoic acid Chemical compound O=C(/C=C/C=C\C\C=C/CCCCCCC(=O)O)CCCCC JEGJFECBWADGJX-RHDCIPCHSA-N 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000005907 alkyl ester group Chemical group 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000019425 cirrhosis of liver Diseases 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 210000002216 heart Anatomy 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 210000001503 joint Anatomy 0.000 claims 1
- 208000017169 kidney disease Diseases 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 210000001370 mediastinum Anatomy 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000008085 renal dysfunction Effects 0.000 claims 1
- 210000000574 retroperitoneal space Anatomy 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 125000005457 triglyceride group Chemical group 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023020423A JP2023065454A (ja) | 2015-05-13 | 2023-02-14 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
| JP2025002652A JP2025061087A (ja) | 2015-05-13 | 2025-01-08 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562160863P | 2015-05-13 | 2015-05-13 | |
| US62/160,863 | 2015-05-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017559093A Division JP2018524274A (ja) | 2015-05-13 | 2016-05-12 | １５−オキソ−ｅｐａまたは１５−オキソ−ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023020423A Division JP2023065454A (ja) | 2015-05-13 | 2023-02-14 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021075563A JP2021075563A (ja) | 2021-05-20 |
| JP2021075563A5 true JP2021075563A5 (enExample) | 2022-01-11 |
| JP7229285B2 JP7229285B2 (ja) | 2023-02-27 |
Family
ID=56131573
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017559093A Pending JP2018524274A (ja) | 2015-05-13 | 2016-05-12 | １５−オキソ−ｅｐａまたは１５−オキソ−ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
| JP2021020446A Active JP7229285B2 (ja) | 2015-05-13 | 2021-02-12 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
| JP2023020423A Withdrawn JP2023065454A (ja) | 2015-05-13 | 2023-02-14 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
| JP2025002652A Pending JP2025061087A (ja) | 2015-05-13 | 2025-01-08 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017559093A Pending JP2018524274A (ja) | 2015-05-13 | 2016-05-12 | １５−オキソ−ｅｐａまたは１５−オキソ−ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023020423A Withdrawn JP2023065454A (ja) | 2015-05-13 | 2023-02-14 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
| JP2025002652A Pending JP2025061087A (ja) | 2015-05-13 | 2025-01-08 | １５－オキソ－ｅｐａまたは１５－オキソ－ｄｇｌａを含む組成物、ならびにその作製及び使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10047033B2 (enExample) |
| EP (1) | EP3294282A1 (enExample) |
| JP (4) | JP2018524274A (enExample) |
| CN (3) | CN117402059A (enExample) |
| HK (1) | HK1250345A1 (enExample) |
| MA (1) | MA47141A (enExample) |
| WO (1) | WO2016181221A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3151825B1 (en) | 2014-06-04 | 2020-03-25 | DS Biopharma Limited | Pharmaceutical compositions comprising dgla and use of same |
| HK1250345A1 (zh) * | 2015-05-13 | 2018-12-14 | Afimmune Limited | 包含15-氧代-epa或15-氧代-dgla的组合物及其制备和使用方法 |
| BR122023026625A2 (pt) | 2015-12-18 | 2024-01-16 | Afimmune Limited | Uso do ácido 15-hidroxieicosapentaenoico ou derivados farmaceuticamente aceitáveis do mesmo |
| WO2020079250A1 (en) * | 2018-10-18 | 2020-04-23 | Ds Biopharma Limited | Dgla and/or 15-hetre for treating inflammatory, fibrotic, and proliferative conditions |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE47777B1 (en) | 1978-01-23 | 1984-06-13 | Efamol Ltd | Pharmaceutical and dietary composition comprising gamma-linolenic acids |
| DE68924714T2 (de) | 1988-01-14 | 1996-05-02 | Anders Frithz | Verwendung von essentiellen fettsäuren zur herstellung eines medikaments zur behandlung von ekzemen. |
| CA1334002C (en) | 1988-09-28 | 1995-01-17 | Barry D. Sears | Essential fatty acid compositions and methods for the modulation of prostaglandin levels in mammals |
| GB9111900D0 (en) | 1991-06-03 | 1991-07-24 | Efamol Holdings | Fatty acid compositions |
| JPH05186342A (ja) * | 1992-01-10 | 1993-07-27 | Fujirebio Inc | 免疫調節作用を併せもつ抗炎症剤 |
| DE4238869C2 (de) | 1992-11-18 | 1994-09-08 | Wogepharm Gmbh | Mittel zur Behandlung des atopischen Ekzems und anderer entzündlicher Hautkrankheiten |
| GB9301446D0 (en) | 1993-01-26 | 1993-03-17 | Scotia Holdings Plc | Internal radiation damage |
| AU673700B2 (en) | 1993-01-27 | 1996-11-21 | Scotia Holdings Plc | Triglycerides |
| BR9405620A (pt) | 1993-10-01 | 1999-09-08 | Scherer Corp R P | Cápsula de gelatina contendo fragrncia, e, processo para sua preparação |
| GB9715444D0 (en) | 1997-07-22 | 1997-09-24 | Scotia Holdings Plc | Therapeutic and dietary compositions |
| JP2000191525A (ja) | 1998-12-25 | 2000-07-11 | Nof Corp | 皮膚外用剤組成物 |
| ATE344226T1 (de) | 2000-02-16 | 2006-11-15 | Brigham & Womens Hospital | Aspirin-ausgelöste lipidmediatoren |
| JP2002047176A (ja) | 2000-08-04 | 2002-02-12 | Idemitsu Technofine Co Ltd | ＩｇＥ産生抑制剤 |
| US20020188024A1 (en) | 2000-08-23 | 2002-12-12 | Chilton Floyd H. | Fatty acid-containing emulsion with increased bioavailability |
| US20040043013A1 (en) | 2000-12-28 | 2004-03-04 | Mccleary Edward Larry | Metabolic uncoupling therapy |
| DE10121252A1 (de) | 2001-04-30 | 2002-11-07 | Christos C Zouboulis | Behandlung der Akne |
| ES2238568T3 (es) | 2001-05-30 | 2005-09-01 | Laxdale Limited | Uso del coenzima q (ubiquinona) y acido eicosapentaenoico (epa) para el tratamiento del linfoma no hodgkin y trastornos psiquiatricos o neurologicos. |
| JP2003155233A (ja) | 2001-11-16 | 2003-05-27 | Idemitsu Technofine Co Ltd | 塗布剤 |
| JPWO2004048497A1 (ja) | 2002-11-22 | 2006-03-30 | 日本水産株式会社 | 高度不飽和脂肪酸、その塩、またはそのエステルを含有する外用組成物 |
| JP2005179211A (ja) | 2003-12-17 | 2005-07-07 | Idemitsu Kosan Co Ltd | 皮膚外用剤組成物 |
| GB2409644B (en) | 2003-12-31 | 2005-12-21 | Igennus Ltd | Formulation comprising eicosapentaenoic acid or an ester thereof and a triterpene or an ester thereof |
| CN101043884A (zh) | 2004-07-01 | 2007-09-26 | 谢彭斯眼科研究公司 | 用于治疗眼部疾病和病症的组合物和方法 |
| US7666447B2 (en) | 2004-10-08 | 2010-02-23 | Pharmanutrients | Compositions including Krill extracts and conjugated linoleic acid and methods of using same |
| US7893106B2 (en) | 2004-11-19 | 2011-02-22 | Martek Biosciences, Corporation | Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same |
| US9006287B2 (en) | 2005-02-14 | 2015-04-14 | Suntory Holdings Limited | Composition comprising dihomo-γ-linolenic acid (DGLA) as active ingredient |
| JP5101894B2 (ja) | 2007-01-15 | 2012-12-19 | サントリーホールディングス株式会社 | 高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
| PE20100156A1 (es) | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
| WO2009154230A1 (ja) | 2008-06-17 | 2009-12-23 | 持田製薬株式会社 | 非アルコール性脂肪肝炎の予防／改善・治療薬 |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| CA2690488C (en) | 2010-01-19 | 2013-06-11 | Accucaps Industries Limited | Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof |
| US20120264824A1 (en) | 2011-04-15 | 2012-10-18 | Mochida Pharmaceutical Co., Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
| US8658787B2 (en) | 2011-09-16 | 2014-02-25 | Galectin Therapeutics Inc. | Galacto-rhamnogalacturonate compositions for the treatment of non-alcoholic steatohepatitis and non-alcoholic fatty liver disease |
| US8293790B2 (en) | 2011-10-19 | 2012-10-23 | Dignity Sciences Limited | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof |
| JP6399655B2 (ja) | 2012-01-06 | 2018-10-03 | オムセラ・ファーマシューティカルズ・インコーポレイテッド | 遊離酸型のオメガ−３多価不飽和脂肪酸のｄｐａ濃縮組成物 |
| US20130267598A1 (en) * | 2012-02-23 | 2013-10-10 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same |
| DK2833740T3 (da) | 2012-04-04 | 2017-01-02 | Pronova Biopharma Norge As | Sammensætninger omfattende omega-3-fedtsyrer og D-vitamin til acne vulgaris og/eller eksem og fremgangsmåder og anvendelser deraf |
| PT2934505T (pt) * | 2012-12-24 | 2021-07-02 | Qualitas Health Inc | Formulação de ácido eicosapentaenoico (epa) |
| GB201301626D0 (en) | 2013-01-30 | 2013-03-13 | Dignity Sciences Ltd | Composition comprising 15-OHEPA and methods of using the same |
| SG11201507288UA (en) * | 2013-03-15 | 2015-10-29 | Mochida Pharm Co Ltd | Compositions and methods for treating non-alcoholic steatohepatitis |
| TWI742541B (zh) | 2013-03-15 | 2021-10-11 | 英商邊緣生物科技有限公司 | 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物 |
| EP3151825B1 (en) | 2014-06-04 | 2020-03-25 | DS Biopharma Limited | Pharmaceutical compositions comprising dgla and use of same |
| MA41120A (fr) | 2014-12-02 | 2017-10-10 | Afimmune Ltd | Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci |
| HK1250345A1 (zh) | 2015-05-13 | 2018-12-14 | Afimmune Limited | 包含15-氧代-epa或15-氧代-dgla的组合物及其制备和使用方法 |
| BR122023026625A2 (pt) | 2015-12-18 | 2024-01-16 | Afimmune Limited | Uso do ácido 15-hidroxieicosapentaenoico ou derivados farmaceuticamente aceitáveis do mesmo |
| WO2017118911A1 (en) | 2016-01-07 | 2017-07-13 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla and use of same |
-
2016
- 2016-05-12 HK HK18109827.0A patent/HK1250345A1/zh unknown
- 2016-05-12 CN CN202311320835.0A patent/CN117402059A/zh active Pending
- 2016-05-12 US US15/153,476 patent/US10047033B2/en active Active
- 2016-05-12 EP EP16729367.9A patent/EP3294282A1/en active Pending
- 2016-05-12 MA MA047141A patent/MA47141A/fr unknown
- 2016-05-12 CN CN202111198132.6A patent/CN113896628A/zh active Pending
- 2016-05-12 WO PCT/IB2016/000732 patent/WO2016181221A1/en not_active Ceased
- 2016-05-12 CN CN201680040919.0A patent/CN107847477A/zh active Pending
- 2016-05-12 JP JP2017559093A patent/JP2018524274A/ja active Pending
-
2018
- 2018-03-14 US US15/921,211 patent/US10570083B2/en active Active
-
2020
- 2020-01-13 US US16/741,015 patent/US20210230094A1/en not_active Abandoned
-
2021
- 2021-02-12 JP JP2021020446A patent/JP7229285B2/ja active Active
- 2021-11-16 US US17/527,440 patent/US12017986B2/en active Active
-
2023
- 2023-02-14 JP JP2023020423A patent/JP2023065454A/ja not_active Withdrawn
-
2025
- 2025-01-08 JP JP2025002652A patent/JP2025061087A/ja active Pending
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