JP2021017402A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021017402A5 JP2021017402A5 JP2019132196A JP2019132196A JP2021017402A5 JP 2021017402 A5 JP2021017402 A5 JP 2021017402A5 JP 2019132196 A JP2019132196 A JP 2019132196A JP 2019132196 A JP2019132196 A JP 2019132196A JP 2021017402 A5 JP2021017402 A5 JP 2021017402A5
- Authority
- JP
- Japan
- Prior art keywords
- cognitive impairment
- mild cognitive
- imidazole dipeptide
- improving mild
- improving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 18
- 108010016626 Dipeptides Proteins 0.000 claims 6
- 208000010877 cognitive disease Diseases 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 208000027061 mild cognitive impairment Diseases 0.000 claims 6
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 claims 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- 108010085443 Anserine Proteins 0.000 claims 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims 2
- 108010087806 Carnosine Proteins 0.000 claims 2
- 241000287828 Gallus gallus Species 0.000 claims 2
- SLRNWACWRVGMKD-UHFFFAOYSA-N L-anserine Natural products CN1C=NC(CC(NC(=O)CCN)C(O)=O)=C1 SLRNWACWRVGMKD-UHFFFAOYSA-N 0.000 claims 2
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims 2
- 241000210053 Potentilla elegans Species 0.000 claims 2
- MYYIAHXIVFADCU-QMMMGPOBSA-N anserine Chemical compound CN1C=NC=C1C[C@H](NC(=O)CC[NH3+])C([O-])=O MYYIAHXIVFADCU-QMMMGPOBSA-N 0.000 claims 2
- 229940044199 carnosine Drugs 0.000 claims 2
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims 2
- 229940109239 creatinine Drugs 0.000 claims 2
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 claims 1
- 241000972773 Aulopiformes Species 0.000 claims 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 229930003268 Vitamin C Natural products 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 235000001785 ferulic acid Nutrition 0.000 claims 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 claims 1
- 229940114124 ferulic acid Drugs 0.000 claims 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 235000019515 salmon Nutrition 0.000 claims 1
- 238000001308 synthesis method Methods 0.000 claims 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 claims 1
- 235000019154 vitamin C Nutrition 0.000 claims 1
- 239000011718 vitamin C Substances 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019132196A JP7321017B2 (ja) | 2019-07-17 | 2019-07-17 | 機能性食品 |
| TW109119147A TWI801737B (zh) | 2019-07-17 | 2020-06-08 | 輕度認知障礙改善用組成物及使用該組成物之輕度認知障礙的改善方法 |
| US16/931,979 US20210015886A1 (en) | 2019-07-17 | 2020-07-17 | Composition for improving mild cognitive impairment and method for improving mild cognitive impairment |
| JP2023064666A JP2023080213A (ja) | 2019-07-17 | 2023-04-12 | 軽度認知障害改善用組成物 |
| JP2023097266A JP2023113933A (ja) | 2019-07-17 | 2023-06-13 | 軽度認知障害改善用組成物 |
| US18/360,773 US20230364180A1 (en) | 2019-07-17 | 2023-07-27 | Composition for improving mild cognitive impairment and method for improving mild cognitive impairment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019132196A JP7321017B2 (ja) | 2019-07-17 | 2019-07-17 | 機能性食品 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023064666A Division JP2023080213A (ja) | 2019-07-17 | 2023-04-12 | 軽度認知障害改善用組成物 |
| JP2023097266A Division JP2023113933A (ja) | 2019-07-17 | 2023-06-13 | 軽度認知障害改善用組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021017402A JP2021017402A (ja) | 2021-02-15 |
| JP2021017402A5 true JP2021017402A5 (https=) | 2022-06-07 |
| JP7321017B2 JP7321017B2 (ja) | 2023-08-04 |
Family
ID=74343267
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019132196A Active JP7321017B2 (ja) | 2019-07-17 | 2019-07-17 | 機能性食品 |
| JP2023064666A Pending JP2023080213A (ja) | 2019-07-17 | 2023-04-12 | 軽度認知障害改善用組成物 |
| JP2023097266A Pending JP2023113933A (ja) | 2019-07-17 | 2023-06-13 | 軽度認知障害改善用組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023064666A Pending JP2023080213A (ja) | 2019-07-17 | 2023-04-12 | 軽度認知障害改善用組成物 |
| JP2023097266A Pending JP2023113933A (ja) | 2019-07-17 | 2023-06-13 | 軽度認知障害改善用組成物 |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US20210015886A1 (https=) |
| JP (3) | JP7321017B2 (https=) |
| TW (1) | TWI801737B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024179725A (ja) * | 2023-06-15 | 2024-12-26 | 日本予防医薬株式会社 | イミダゾールジペプチドおよび黒大豆種皮抽出物を含有する組成物 |
| JP7714085B1 (ja) | 2024-05-10 | 2025-07-28 | 森永乳業株式会社 | 密封容器入り飲食品及び密封容器入り飲食品の製造方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0920661A (ja) * | 1995-07-04 | 1997-01-21 | Suntory Ltd | 学習能力向上組成物 |
| JP4023648B2 (ja) * | 1999-01-13 | 2007-12-19 | 日本ハム株式会社 | 皮膚代謝促進物及び機能性食品 |
| ATE328596T1 (de) * | 2001-03-16 | 2006-06-15 | Suntory Ltd | Autonomsystem kontrollagentien und gesundheitsgetränke und -nahrungsmittel |
| WO2003013514A1 (en) | 2001-08-08 | 2003-02-20 | Carn-Aware Llc | Improving neurological functions |
| JP5089025B2 (ja) | 2004-04-30 | 2012-12-05 | 東海物産株式会社 | 抗酸化組成物 |
| JP2007070316A (ja) * | 2005-09-09 | 2007-03-22 | Nippon Meat Packers Inc | 経口用組成物及び栄養補助食品 |
| JP5142126B2 (ja) | 2007-08-22 | 2013-02-13 | 東海物産株式会社 | 抗酸化性ジペプチドの製造方法 |
| JP2013526518A (ja) | 2010-05-13 | 2013-06-24 | ザ ユニバーシティ オブ ケンタッキー リサーチ ファウンデーション | Ｍｃｉおよびアルツハイマー病の処置 |
| JP2014142910A (ja) * | 2012-12-28 | 2014-08-07 | Panasonic Corp | 制御装置、発電制御装置、太陽光発電システム、制御方法、及び発電制御方法 |
| JP2015193582A (ja) | 2014-03-28 | 2015-11-05 | 国立大学法人 東京大学 | イミダゾールジペプチドを含む剤 |
| KR101734645B1 (ko) | 2015-05-18 | 2017-05-11 | (주)에이엔티랩스 | 초기 알츠하이머 병 또는 경도 인지 장애 진단 방법 |
| JP6550357B2 (ja) | 2016-08-24 | 2019-07-24 | 日本ハム株式会社 | イミダゾールジペプチドを含有する、グリア細胞における神経栄養因子等の遺伝子の発現誘導剤 |
| JP6934774B2 (ja) | 2016-12-27 | 2021-09-15 | 東海物産株式会社 | イミダゾールジペプチド合成活性を有するタンパク質及びイミダゾールジペプチドの製造方法 |
-
2019
- 2019-07-17 JP JP2019132196A patent/JP7321017B2/ja active Active
-
2020
- 2020-06-08 TW TW109119147A patent/TWI801737B/zh active
- 2020-07-17 US US16/931,979 patent/US20210015886A1/en not_active Abandoned
-
2023
- 2023-04-12 JP JP2023064666A patent/JP2023080213A/ja active Pending
- 2023-06-13 JP JP2023097266A patent/JP2023113933A/ja active Pending
- 2023-07-27 US US18/360,773 patent/US20230364180A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SA521422625B1 (ar) | مركبات بنزوثيادايازيبين واستخدامها كمعدلات لحمض الصفراء | |
| Bourgonje et al. | N-acetylcysteine and hydrogen sulfide in coronavirus disease 2019 | |
| SA522432741B1 (ar) | مركبات بنزوثيا (داي) أزيبين واستخدامها كمعدِّلات للأحماض الصفراوية | |
| JOP20230302A1 (ar) | مركبات بنزوثيا(داي) أزيبين واستخدامها كمعدلات لحمض الصفراء | |
| Teixeira et al. | Safinamide: a new hope for Parkinson’s disease? | |
| WO2019055966A3 (en) | PYRIDAZINONES AND METHODS OF USE | |
| MA40111A1 (fr) | Dérivés du tétrahydronaphtalène inhibant la protéine mcl-1 | |
| WO2019133770A3 (en) | Glycolate oxidase inhibitors for the treatment of disease | |
| MA30766B1 (fr) | Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide | |
| MA40887B1 (fr) | Nouveaux dérivés de 4-méthoxy pyrrole ou leurs sels, et composition pharmaceutique les comprenant | |
| JP2021017402A5 (https=) | ||
| Gangula et al. | Polybacterial periodontal pathogens alter vascular and gut BH4/nNOS/NRF2-phase II enzyme expression | |
| WO2006034154A3 (en) | Salts of 5-azacytidine | |
| UA102254C2 (ru) | Жидкий состав для деферипрона с приятным вкусом | |
| WO2010076033A9 (en) | Toluidine sulfonamides and their use | |
| NO20071231L (no) | Nye anvendelser av 2-fenyl-substituerte imidazotriazinonderivater | |
| JP2015218140A (ja) | 抗酸化サプリメント | |
| MX2025000556A (es) | Composiciones agricolas y metodos | |
| MX2020009050A (es) | Productos y metodos de combinacion natural para la regulacion de la funcion del sistema renal y excretorio. | |
| Zainuddin et al. | Epigenetic modulations and nutrient interactions in Alzheimer's disease: unveiling potential therapeutic pathways | |
| Singh et al. | Genome-based multi-targeting of cancer: hype or hope? | |
| JP4949661B2 (ja) | ＨＭＧ−ＣｏＡリダクターゼ阻害剤とグルタチオンを含有する医薬組成物 | |
| WO2019039836A3 (ko) | 퇴행성 신경질환 치료용 복합 제형 조성물 | |
| Victoria Montesinos et al. | Polyphenols in mtDNA Repair, Mitochondrial Biogenesis, and Mitophagy: An Integrative Review | |
| TR2023017232A2 (tr) | 5 mg ve 10 mg melatoni̇n i̇çeren farmasöti̇k formülasyonlar |