MA30766B1 - Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide - Google Patents
Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioideInfo
- Publication number
- MA30766B1 MA30766B1 MA31733A MA31733A MA30766B1 MA 30766 B1 MA30766 B1 MA 30766B1 MA 31733 A MA31733 A MA 31733A MA 31733 A MA31733 A MA 31733A MA 30766 B1 MA30766 B1 MA 30766B1
- Authority
- MA
- Morocco
- Prior art keywords
- dosage forms
- pharmaceutical dosage
- opioid analgesic
- oral pharmaceutical
- forms anti
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/02—Mixing; Kneading non-continuous, with mechanical mixing or kneading devices, i.e. batch type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/80—Component parts, details or accessories; Auxiliary operations
- B29B7/88—Adding charges, i.e. additives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/04—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam
- B29C35/045—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam using gas or flames
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/16—Cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C37/00—Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
- B29C37/0025—Applying surface layers, e.g. coatings, decorative layers, printed layers, to articles during shaping, e.g. in-mould printing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/003—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/52—Heating or cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
- B29C71/009—After-treatment of articles without altering their shape; Apparatus therefor using gases without chemical reaction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/04—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam
- B29C35/045—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam using gas or flames
- B29C2035/046—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam using gas or flames dried air
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/16—Cooling
- B29C2035/1658—Cooling using gas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2071/00—Use of polyethers, e.g. PEEK, i.e. polyether-etherketone or PEK, i.e. polyetherketone or derivatives thereof, as moulding material
- B29K2071/02—Polyalkylene oxides, e.g. PEO, i.e. polyethylene oxide, or derivatives thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/25—Solid
- B29K2105/251—Particles, powder or granules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0088—Molecular weight
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
Abstract
L'INVENTION CONCERNE DES FORMES POSOLOGIQUES PHARMACEUTIQUES, PAR EXEMPLE UNE FORME POSOLOGIQUE INVIOLABLE COMPRENANT UN ANALGÉSIQUE OPIOÏDE, ET LEURS PROCÉDÉS DE FABRICATION, LEURS UTILISATIONS ET DES PROCÉDÉS DE TRAITEMENT PAR CES FORMES POSOLOGIQUES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84024406P | 2006-08-25 | 2006-08-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA30766B1 true MA30766B1 (fr) | 2009-10-01 |
Family
ID=38754532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA31733A MA30766B1 (fr) | 2006-08-25 | 2009-03-24 | Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide |
Country Status (42)
Families Citing this family (149)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
JP4865330B2 (ja) | 2002-12-13 | 2012-02-01 | デュレクト コーポレーション | 経口ドラッグデリバリーシステム |
ATE495732T1 (de) | 2003-03-26 | 2011-02-15 | Egalet As | Morphin-system mit kontrollierter freisetzung |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US20070048228A1 (en) * | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
EP3326617A1 (fr) | 2004-06-12 | 2018-05-30 | Collegium Pharmaceutical, Inc. | Formulations de médicaments empêchant |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
PT2767292T (pt) | 2004-09-17 | 2016-11-23 | Durect Corp | Composição anestésica local prolongada contendo aibs |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
AU2006254554B2 (en) * | 2005-06-03 | 2011-11-24 | Egalet Ltd | A solid pharmaceutical composition with a first fraction of a dispersion medium and a second fraction of a matrix, the latter being at least partially first exposed to gastrointestinal fluids |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
SA07280459B1 (ar) * | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
ES2388355T3 (es) | 2006-11-03 | 2012-10-11 | Durect Corporation | Sistemas de suministro transdémico que comprenden bupivacaína |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
US10512644B2 (en) | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
EP2155167A2 (fr) | 2007-06-04 | 2010-02-24 | Egalet A/S | Compositions pharmaceutiques à libération contrôlée pour un effet prolongé |
US20080318994A1 (en) * | 2007-06-21 | 2008-12-25 | Endo Pharmaceuticals, Inc. | Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instruction on Dosing for Renal Impairment |
CN101801350A (zh) | 2007-08-13 | 2010-08-11 | 阿巴斯迪特宁医药有限公司 | 抗滥用药物、使用方法和制备方法 |
WO2009088414A2 (fr) | 2007-12-06 | 2009-07-16 | Durect Corporation | Formes posologiques pharmaceutiques orales |
US8383152B2 (en) | 2008-01-25 | 2013-02-26 | Gruenenthal Gmbh | Pharmaceutical dosage form |
US8372432B2 (en) | 2008-03-11 | 2013-02-12 | Depomed, Inc. | Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic |
EP2262484B1 (fr) * | 2008-03-11 | 2013-01-23 | Depomed, Inc. | Formes médicamenteuses à libération étendue de rétention gastrique comprenant des combinaisons d'un analgésique non opioïde et d'un analgésique opioïde |
HUE030803T2 (en) | 2008-05-09 | 2017-06-28 | Gruenenthal Gmbh | Process for the preparation of an intermediate powder formulation and a final solid dosage form using a spraying step \ t |
US20110165248A1 (en) * | 2008-09-18 | 2011-07-07 | Meridith Lee Machonis | Pharmaceutical dosage forms comprising poly(e-caprolactone) |
US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
ES2414856T3 (es) | 2008-12-12 | 2013-07-23 | Paladin Labs Inc. | Formulaciones de fármaco narcótico con potencial de adicción disminuido |
WO2010088911A1 (fr) | 2009-02-06 | 2010-08-12 | Egalet A/S | Compositions pharmaceutiques résistant à une maltraitance |
NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
US20100280059A1 (en) * | 2009-05-01 | 2010-11-04 | Atley Pharmaceuticals, Inc. | Compositions comprising an antihistamine, antitussive and decongestant in extended release formulations |
JP2012525423A (ja) * | 2009-05-01 | 2012-10-22 | アトリー ファーマシューティカルズ インコーポレイテッド | 抗ヒスタミン剤と鎮咳剤と充血緩和剤とを徐放性製剤中に含む組成物 |
NZ603579A (en) | 2009-06-24 | 2014-02-28 | Egalet Ltd | Controlled release formulations |
RU2555531C2 (ru) | 2009-07-22 | 2015-07-10 | Грюненталь Гмбх | Защищенная от применения не по назначению лекарственная форма для чувствительных к окислению опиоидов |
KR101738369B1 (ko) | 2009-07-22 | 2017-05-22 | 그뤼넨탈 게엠베하 | 핫 멜트 압출된 제어 방출 투여형 |
WO2011026125A2 (fr) * | 2009-08-31 | 2011-03-03 | Depomed, Inc. | Compositions pharmaceutiques à rétention gastrique permettant une libération immédiate et prolongée d'acétaminophène |
EP3064064A1 (fr) | 2009-09-30 | 2016-09-07 | Acura Pharmaceuticals, Inc. | Procédés et compositions de dissuasion d'abus |
US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US8597681B2 (en) | 2009-12-22 | 2013-12-03 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
US9198861B2 (en) | 2009-12-22 | 2015-12-01 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
US9579285B2 (en) | 2010-02-03 | 2017-02-28 | Gruenenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of an extruder |
EP2568965A1 (fr) | 2010-05-10 | 2013-03-20 | Euro-Celtique S.A. | Combinaison de granules chargés de principe actif et de principes actifs supplémentaires |
NZ700732A (en) | 2010-05-10 | 2015-08-28 | Euro Celtique Sa | Pharmaceutical compositions comprising hydromorphone and naloxone |
WO2011141489A1 (fr) | 2010-05-10 | 2011-11-17 | Euro-Celtique S.A. | Fabrication de granules sans principe actif et comprimés les comprenant |
AR081931A1 (es) | 2010-06-15 | 2012-10-31 | Gruenenthal Gmbh | Combinacion farmaceutica |
EP2611426B1 (fr) | 2010-09-02 | 2014-06-25 | Grünenthal GmbH | Forme pharmaceutique inviolable comportant un sel inorganique |
AR082862A1 (es) | 2010-09-02 | 2013-01-16 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteracion que comprende un polimero anionico |
AU2011342893A1 (en) | 2010-12-13 | 2013-05-02 | Purdue Pharma L.P. | Controlled release dosage forms |
CN104856966A (zh) * | 2010-12-22 | 2015-08-26 | 普渡制药公司 | 包覆的抗篡改控制释放剂型 |
EP2826468A1 (fr) * | 2010-12-22 | 2015-01-21 | Purdue Pharma L.P. | Formes posologiques à libération contrôlée enchâssées et inviolables |
CN103327969A (zh) | 2010-12-23 | 2013-09-25 | 普渡制药公司 | 抗篡改固体口服剂型 |
HUE026981T2 (en) * | 2011-03-25 | 2016-08-29 | Purdue Pharma Lp | Regulated release dosage forms |
US8858963B1 (en) | 2011-05-17 | 2014-10-14 | Mallinckrodt Llc | Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia |
US8741885B1 (en) | 2011-05-17 | 2014-06-03 | Mallinckrodt Llc | Gastric retentive extended release pharmaceutical compositions |
US9050335B1 (en) | 2011-05-17 | 2015-06-09 | Mallinckrodt Llc | Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia |
AT511581A1 (de) | 2011-05-26 | 2012-12-15 | G L Pharma Gmbh | Orale retardierende formulierung |
EA201400172A1 (ru) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства |
AR087359A1 (es) | 2011-07-29 | 2014-03-19 | Gruenenthal Gmbh | Tableta a prueba de alteracion que proporciona liberacion inmediata del farmaco |
US20140341984A1 (en) * | 2011-09-16 | 2014-11-20 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
WO2013038268A1 (fr) * | 2011-09-16 | 2013-03-21 | Purdue Pharma L.P. | Formulations à libération immédiate résistant au détournement d'utilisation |
MX356210B (es) * | 2011-10-18 | 2018-05-18 | Purdue Pharma Lp | Formulaciones de polimero acrilico. |
EA201400590A1 (ru) | 2011-11-17 | 2014-11-28 | Грюненталь Гмбх | Устойчивая к разрушению пероральная фармацевтическая лекарственная форма, содержащая фармакологически активный ингредиент, опиоидный антагонист и/или средство, вызывающее отвращение, полиалкиленоксид и анионный полимер |
EP2782558A4 (fr) * | 2011-11-22 | 2015-03-18 | Watson Pharmaceuticals Inc | Comprimé anti-abus à libération immédiate |
TW201336529A (zh) * | 2011-12-09 | 2013-09-16 | Purdue Pharma Lp | 包含聚(ε-己內酯)和聚氧化乙烯之藥物劑量型 |
EP2819656A1 (fr) | 2012-02-28 | 2015-01-07 | Grünenthal GmbH | Forme pharmaceutique inviolable comprenant un composé pharmacologiquement actif et un polymère anionique |
MX362357B (es) | 2012-04-18 | 2019-01-14 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis. |
JP6067100B2 (ja) | 2012-04-18 | 2017-01-25 | マリンクロッド エルエルシー | 即放性乱用抑止医薬組成物 |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
CA2877183A1 (fr) | 2012-07-06 | 2014-01-09 | Egalet Ltd. | Compositions pharmaceutiques de dissuasion d'abus a liberation controlee |
CA2877774C (fr) | 2012-07-12 | 2017-07-18 | Mallinckrodt Llc | Compositions pharmaceutiques de dissuasion d'abus a liberation prolongee |
EP3446685A1 (fr) | 2012-11-30 | 2019-02-27 | Acura Pharmaceuticals, Inc. | Libération auto-régulée d'ingrédient pharmaceutique actif |
KR101840526B1 (ko) | 2013-02-05 | 2018-03-20 | 퍼듀 퍼머 엘피 | 내변조성 제약 제제 |
US9572885B2 (en) | 2013-03-15 | 2017-02-21 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
WO2014146093A2 (fr) | 2013-03-15 | 2014-09-18 | Inspirion Delivery Technologies, Llc | Compositions anti-abus et méthodes d'utilisation |
JP6255474B2 (ja) | 2013-03-15 | 2017-12-27 | マリンクロッド エルエルシー | 機能的割線を有する即時放出用の乱用抑止性固体剤形 |
US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
AR096439A1 (es) | 2013-05-29 | 2015-12-30 | Gruenenthal Gmbh | Forma de dosificación resistente al uso indebido que contiene una o más partículas |
JP6445537B2 (ja) | 2013-05-29 | 2018-12-26 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 1個または複数の粒子を含有する改変防止(tamper−resistant)剤形 |
EA032465B1 (ru) | 2013-07-12 | 2019-05-31 | Грюненталь Гмбх | Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления |
US10195153B2 (en) | 2013-08-12 | 2019-02-05 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
NZ719087A (en) | 2013-11-13 | 2017-12-22 | Euro Celtique Sa | Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome |
AU2014356581C1 (en) | 2013-11-26 | 2020-05-28 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US10632113B2 (en) | 2014-02-05 | 2020-04-28 | Kashiv Biosciences, Llc | Abuse-resistant drug formulations with built-in overdose protection |
CA2943728C (fr) | 2014-03-26 | 2020-03-24 | Sun Pharma Advanced Research Company Ltd. | Forme galenique solide de matrice biphasique a liberation immediate et dissuasive d'abus |
AU2015261060A1 (en) | 2014-05-12 | 2016-11-03 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising Tapentadol |
CA2949422A1 (fr) | 2014-05-26 | 2015-12-03 | Grunenthal Gmbh | Microparticules protegees contre une liberation massive dans l'ethanol |
ES2963078T3 (es) | 2014-07-03 | 2024-03-25 | SpecGx LLC | Formulaciones de liberación inmediata disuasorias del abuso que comprenden polisacáridos no celulósicos |
EP3169315B1 (fr) | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Forme posologique remplie de liquide anti-abus à libération immédiate |
US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
JP5888387B1 (ja) * | 2014-10-22 | 2016-03-22 | ミツミ電機株式会社 | 電池保護回路及び電池保護装置、並びに電池パック |
BR112017022856A2 (pt) | 2015-04-24 | 2018-07-17 | Gruenenthal Gmbh | combinação de dose fixa inviolável que proporciona rápida liberação de duas drogas a partir de partículas |
EP3285745A1 (fr) | 2015-04-24 | 2018-02-28 | Grünenthal GmbH | Forme galénique inviolable avec libération immédiate et résistance à l'extraction par solvant. |
US20160310428A1 (en) | 2015-04-24 | 2016-10-27 | Grunenthal Gmbh | Tamper-resistant fixed dose combination providing fast release of two drugs from different particles |
US20160310486A1 (en) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Tamper-resistant fixed dose combination providing fast release of two drugs from particles and a matrix |
US11103581B2 (en) | 2015-08-31 | 2021-08-31 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
WO2017059374A1 (fr) * | 2015-09-30 | 2017-04-06 | Kashiv Pharma Llc | Formulation de médicament à libération immédiate de dissuasion d'abus et anti-surdose |
US9861629B1 (en) | 2015-10-07 | 2018-01-09 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
US20180303757A1 (en) * | 2015-10-23 | 2018-10-25 | Kashiv Pharma Llc | Enhanced abuse-deterrent formulations of oxycodone |
WO2017139106A1 (fr) | 2016-02-08 | 2017-08-17 | Mallinckrodt Llc | Compositions pharmaceutiques contenant du glucomannane à libération prolongée et avec des propriétés de dissuasion d'abus |
JP6323846B2 (ja) * | 2016-04-07 | 2018-05-16 | 塩野義製薬株式会社 | オピオイドを含有する乱用防止製剤 |
US20170296476A1 (en) | 2016-04-15 | 2017-10-19 | Grünenthal GmbH | Modified release abuse deterrent dosage forms |
US10335405B1 (en) | 2016-05-04 | 2019-07-02 | Patheon Softgels, Inc. | Non-burst releasing pharmaceutical composition |
WO2017222575A1 (fr) | 2016-06-23 | 2017-12-28 | Collegium Pharmaceutical, Inc. | Procédé de préparation de formulations orales dissuasives d'abus plus stables |
US20180028670A1 (en) | 2016-08-01 | 2018-02-01 | Grünenthal GmbH | Tamper resistant dosage form comprising an anionic polysaccharide |
JP2019524761A (ja) | 2016-08-12 | 2019-09-05 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | エフェドリン及びその誘導体の改変防止製剤 |
DE202016105585U1 (de) * | 2016-10-06 | 2017-01-23 | L.B. Bohle Maschinen + Verfahren Gmbh | Anlage zur Herstellung pharmazeutischer Tabletten |
USD857156S1 (en) * | 2016-11-02 | 2019-08-20 | Innovative Water Care, Llc | Chemical tablet for aquatic systems |
EP3554548A4 (fr) | 2016-12-19 | 2020-08-19 | The Regents of The University of California | Formulations de pilules non broyables |
KR102051132B1 (ko) * | 2017-03-17 | 2019-12-02 | 주식회사 종근당 | 미라베그론 또는 이의 염을 포함하는 방출조절용 약제학적 조성물 |
US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
WO2019003062A1 (fr) * | 2017-06-29 | 2019-01-03 | Zenvision Pharma Llp | Forme galénique inviolable comprenant un agent pharmaceutiquement actif |
US10376471B2 (en) * | 2017-07-10 | 2019-08-13 | Gel Cap Technologies, LLC | Dual release dosage form capsule and methods, devices and systems for making same |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
WO2019073028A1 (fr) | 2017-10-13 | 2019-04-18 | Grünenthal GmbH | Formes posologiques à libération modifiée, dissuasives d'abus |
JP7293209B2 (ja) * | 2017-10-20 | 2023-06-19 | パーデュー、ファーマ、リミテッド、パートナーシップ | 医薬剤形 |
AU2018390826A1 (en) * | 2017-12-20 | 2020-03-12 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
US10624856B2 (en) | 2018-01-31 | 2020-04-21 | Dharma Laboratories LLC | Non-extractable oral solid dosage forms |
TW202002957A (zh) | 2018-02-09 | 2020-01-16 | 德商歌林達有限公司 | 包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物 |
CA3111353A1 (fr) * | 2018-09-06 | 2020-03-12 | Fachhochschule Nordwestschweiz | Formulation a liberation controlee de medicament |
CA3112030A1 (fr) | 2018-09-25 | 2020-04-02 | SpecGx LLC | Formes posologiques de capsules a liberation immediate anti-abus |
WO2020070547A1 (fr) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
EP3860579A1 (fr) | 2018-10-05 | 2021-08-11 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
WO2020070706A1 (fr) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
EP3863617A1 (fr) | 2018-10-11 | 2021-08-18 | Clexio Biosciences Ltd. | Eskétamine pour une utilisation dans le traitement d'un trouble dépressif majeur |
WO2020079699A1 (fr) * | 2018-10-16 | 2020-04-23 | M.O Advanced Technologies (Moat) Ltd | Appareil et procédé permettant de prédire une propension de défauts de comprimé |
CN111251521B (zh) * | 2018-12-03 | 2022-07-22 | 沈欣 | 液态珠丸的制造方法 |
EP3698776A1 (fr) | 2019-02-19 | 2020-08-26 | Grünenthal GmbH | Forme posologique inviolable à libération immédiate et résistance à l'extraction par solvant |
CA3138100A1 (fr) | 2019-04-17 | 2020-10-22 | Compass Pathfinder Limited | Traitement de la depression et de divers autres troubles au moyen de psilocybine |
CN110946086B (zh) * | 2019-12-04 | 2023-05-12 | 北京猫猫狗狗科技有限公司 | 一种下料装置以及下料控制方法 |
WO2021137147A1 (fr) | 2019-12-30 | 2021-07-08 | Clexio Biosciences Ltd. | Régime posologique à base d'eskétamine pour le traitement d'un trouble dépressif majeur |
WO2021137148A1 (fr) | 2019-12-30 | 2021-07-08 | Clexio Biosciences Ltd. | Régime posologique à base d'eskétamine pour le traitement de troubles neuropsychiatriques ou neurologiques |
CN115666621A (zh) | 2020-01-13 | 2023-01-31 | 度勒科特公司 | 具有减少的杂质的持续释放药物递送系统及相关方法 |
USD943706S1 (en) * | 2020-06-10 | 2022-02-15 | Emily Florence Johns | Shower steamer |
CN114659554B (zh) * | 2022-03-01 | 2023-04-25 | 安徽农业大学 | 一种生物质颗粒机故障诊断方法 |
Family Cites Families (297)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1485673A (en) * | 1924-03-04 | Ministrator | ||
US1468805A (en) | 1923-09-25 | Htabtin ereund | ||
US1479293A (en) | 1924-01-01 | Hiabtor fbettlid | ||
US636438A (en) | 1899-02-08 | 1899-11-07 | Charles H Lovejoy | Molder's chaplet. |
US2654756A (en) | 1949-10-20 | 1953-10-06 | Mallinckrodt Chemical Works | Process of preparing codeinone, dihydrocodeinone, and dihydromorphinone |
US2772270A (en) | 1954-10-21 | 1956-11-27 | M J Lewenstein | 14-hydroxymorphinone and 8, 14-dihydroxydihydromorphinone |
US3096248A (en) | 1959-04-06 | 1963-07-02 | Rexall Drug & Chemical Company | Method of making an encapsulated tablet |
US3097144A (en) | 1960-10-14 | 1963-07-09 | Upjohn Co | Heat-cured, polymeric, medicinal dosage film coatings containing a polyvinylpyrrolidone copolymer, polyethenoid acid, and polyethylene glycol |
US3806603A (en) * | 1969-10-13 | 1974-04-23 | W Gaunt | Pharmaceutical carriers of plasticized dried milled particles of hydrated cooked rice endosperm |
US3885027A (en) | 1971-04-12 | 1975-05-20 | West Laboratories Inc | Orally administered drug composition for therapy in the treatment of narcotic drug addiction |
US3966747A (en) * | 1972-10-26 | 1976-06-29 | Bristol-Myers Company | 9-Hydroxy-6,7-benzomorphans |
US3888027A (en) | 1973-07-30 | 1975-06-10 | Kennametal Inc | Arrangement for enhancing blade life |
US3980766A (en) | 1973-08-13 | 1976-09-14 | West Laboratories, Inc. | Orally administered drug composition for therapy in the treatment of narcotic drug addiction |
US3941865A (en) * | 1973-12-10 | 1976-03-02 | Union Carbide Corporation | Extrusion of ethylene oxide resins |
DE2530563C2 (de) * | 1975-07-09 | 1986-07-24 | Bayer Ag, 5090 Leverkusen | Analgetische Arzneimittel mit vermindertem Mißbrauchspotential |
GB1598458A (en) | 1977-04-01 | 1981-09-23 | Hoechst Uk Ltd | Tableting of microcapsules |
US4175119A (en) | 1978-01-11 | 1979-11-20 | Porter Garry L | Composition and method to prevent accidental and intentional overdosage with psychoactive drugs |
US4211681A (en) | 1978-08-16 | 1980-07-08 | Union Carbide Corporation | Poly(ethylene oxide) compositions |
CA1146866A (fr) | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Procede de production d'un compose pharmaceutique a liberation continue sous forme solide |
DE3002664C2 (de) | 1980-01-25 | 1989-05-18 | Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg | Weiche Kontaktlinse |
IL70071A (en) | 1982-11-01 | 1987-12-31 | Merrell Dow Pharma | Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient |
US4501828A (en) * | 1983-01-20 | 1985-02-26 | General Technology Applications,Inc. | Dissolving water soluble polymers |
US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
US4765989A (en) * | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
FR2557459B1 (fr) | 1984-01-02 | 1986-05-30 | Lhd Lab Hygiene Dietetique | Matrice inerte a base de polycaprolactone pour administration orale d'un medicament, et procede de preparation de la forme galenique comprenant cette matrice |
US4599342A (en) | 1984-01-16 | 1986-07-08 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
US4629621A (en) | 1984-07-23 | 1986-12-16 | Zetachron, Inc. | Erodible matrix for sustained release bioactive composition |
AU592065B2 (en) | 1984-10-09 | 1990-01-04 | Dow Chemical Company, The | Sustained release dosage form based on highly plasticized cellulose ether gels |
GB8507779D0 (en) | 1985-03-26 | 1985-05-01 | Fujisawa Pharmaceutical Co | Drug carrier |
US4616644A (en) | 1985-06-14 | 1986-10-14 | Johnson & Johnson Products, Inc. | Hemostatic adhesive bandage |
AU583639B2 (en) | 1985-06-24 | 1989-05-04 | Pitman-Moore Australia Limited | Ingestible capsules |
US4619988A (en) | 1985-06-26 | 1986-10-28 | Allied Corporation | High strength and high tensile modulus fibers or poly(ethylene oxide) |
EP0328775B1 (fr) | 1985-06-28 | 1993-10-20 | Carrington Laboratories, Inc. | Procédé de préparation de produits d'aloès, produits et compositions fabriqués selon lesdits procédés |
US4851521A (en) | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
DE3689650T2 (de) | 1985-12-17 | 1994-05-26 | United States Surgical Corp | Bioresorbierbare Polymere von hohem Molekulargewicht und Implantate davon. |
US4764378A (en) | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
US4713243A (en) | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
USRE33093E (en) | 1986-06-16 | 1989-10-17 | Johnson & Johnson Consumer Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
US4861598A (en) * | 1986-07-18 | 1989-08-29 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
US4970075A (en) | 1986-07-18 | 1990-11-13 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
EP0277289B8 (fr) | 1986-11-10 | 2003-05-21 | Biopure Corporation | Substitut du sang, semi-synthétique, extrêmement pur |
US4892778A (en) * | 1987-05-27 | 1990-01-09 | Alza Corporation | Juxtaposed laminated arrangement |
US5019397A (en) * | 1988-04-21 | 1991-05-28 | Alza Corporation | Aqueous emulsion for pharmaceutical dosage form |
US5160743A (en) | 1988-04-28 | 1992-11-03 | Alza Corporation | Annealed composition for pharmaceutically acceptable drug |
US5162504A (en) | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
US4960814A (en) | 1988-06-13 | 1990-10-02 | Eastman Kodak Company | Water-dispersible polymeric compositions |
US5350741A (en) | 1988-07-30 | 1994-09-27 | Kanji Takada | Enteric formulations of physiologically active peptides and proteins |
US5139790A (en) * | 1988-10-14 | 1992-08-18 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
US5004601A (en) * | 1988-10-14 | 1991-04-02 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
US5202128A (en) | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
US5330766A (en) | 1989-01-06 | 1994-07-19 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
US5051222A (en) | 1989-09-01 | 1991-09-24 | Air Products And Chemicals, Inc. | Method for making extrudable polyvinyl alcohol compositions |
EP0418596A3 (en) | 1989-09-21 | 1991-10-23 | American Cyanamid Company | Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form |
US5169645A (en) | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
US5200197A (en) * | 1989-11-16 | 1993-04-06 | Alza Corporation | Contraceptive pill |
GB8926612D0 (en) | 1989-11-24 | 1990-01-17 | Erba Farmitalia | Pharmaceutical compositions |
FR2664851B1 (fr) * | 1990-07-20 | 1992-10-16 | Oreal | Procede de compactage d'un melange pulverulent permettant d'obtenir un produit compact absorbant ou partiellement delitable et produit obtenu par ce procede. |
SE9003904D0 (sv) | 1990-12-07 | 1990-12-07 | Astra Ab | Method for the manufacture of a pharmaceutical dosage form |
US5273758A (en) * | 1991-03-18 | 1993-12-28 | Sandoz Ltd. | Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms |
WO1993006723A1 (fr) | 1991-10-04 | 1993-04-15 | Olin Corporation | Comprime fongicide |
US5405366A (en) * | 1991-11-12 | 1995-04-11 | Nepera, Inc. | Adhesive hydrogels having extended use lives and process for the preparation of same |
US5266331A (en) | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
US5656295A (en) * | 1991-11-27 | 1997-08-12 | Euro-Celtique, S.A. | Controlled release oxycodone compositions |
ATE140620T1 (de) | 1991-12-05 | 1996-08-15 | Mallinckrodt Veterinary Inc | Glasartige kohlenhydratenmatrize zur verabreichung von heilmitteln mit verzögerter wirkstoffabgabe |
EP0617612B1 (fr) | 1991-12-18 | 1997-09-10 | Warner-Lambert Company | Procede de preparation d'une dispersion solide |
US5968551A (en) | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5958459A (en) | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
US5286493A (en) * | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
US5478577A (en) | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
US5472712A (en) | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5273760A (en) | 1991-12-24 | 1993-12-28 | Euroceltigue, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
DE69216642T2 (de) | 1992-01-13 | 1997-05-07 | Pfizer | Verfahren zur herstellung von tabletten mit hoher festigkeit |
US5393528A (en) * | 1992-05-07 | 1995-02-28 | Staab; Robert J. | Dissolvable device for contraception or delivery of medication |
US5324351A (en) | 1992-08-13 | 1994-06-28 | Euroceltique | Aqueous dispersions of zein and preparation thereof |
DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
AU682827B2 (en) * | 1992-09-18 | 1997-10-23 | Astellas Pharma Inc. | Sustained-release hydrogel preparation |
FI101039B (fi) | 1992-10-09 | 1998-04-15 | Eeva Kristoffersson | Menetelmä lääkepellettien valmistamiseksi |
AU679937B2 (en) | 1992-11-18 | 1997-07-17 | Johnson & Johnson Consumer Products, Inc. | Extrudable compositions for topical or transdermal drug delivery |
FR2701152B1 (fr) | 1993-02-03 | 1995-03-10 | Digipress Sa | Procédé de fabrication d'un disque maître pour la réalisation d'une matrice de pressage notamment de disques optiques, matrice de pressage obtenue par ce procédé et disque optique obtenu à partir de cette matrice de pressage. |
DE4309528C2 (de) | 1993-03-24 | 1998-05-20 | Doxa Gmbh | Folie oder Folienschlauch aus Casein, Verfahren zu deren Herstellung und deren Verwendung |
IL119660A (en) | 1993-05-10 | 2002-09-12 | Euro Celtique Sa | Controlled release formulation comprising tramadol |
EP0647448A1 (fr) | 1993-10-07 | 1995-04-12 | Euroceltique S.A. | Compositions pharmaceutiques administrables par voie oral à base d'opioides analgésiques à action prolongée |
US5500227A (en) | 1993-11-23 | 1996-03-19 | Euro-Celtique, S.A. | Immediate release tablet cores of insoluble drugs having sustained-release coating |
KR100354702B1 (ko) | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
ES2168290T3 (es) | 1993-11-23 | 2002-06-16 | Euro Celtique Sa | Metodo para preparar una composicion de liberacion sostenida. |
GB9401894D0 (en) | 1994-02-01 | 1994-03-30 | Rhone Poulenc Rorer Ltd | New compositions of matter |
WO1995022318A1 (fr) | 1994-02-17 | 1995-08-24 | Pankaj Modi | Medicaments, vaccins et hormones incorpores dans des microspheres recouvertes de polylactides |
CA2182282C (fr) | 1994-02-16 | 2006-04-18 | Jacqueline E. Briskin | Mode de preparation de formulations pharmaceutiques a fines particules |
US5458887A (en) | 1994-03-02 | 1995-10-17 | Andrx Pharmaceuticals, Inc. | Controlled release tablet formulation |
JP2977907B2 (ja) | 1994-05-06 | 1999-11-15 | ファイザー・インコーポレーテッド | アジスロマイシンの放出調節された剤形 |
AT403988B (de) | 1994-05-18 | 1998-07-27 | Lannacher Heilmittel | Festes orales retardpräparat |
US5460826A (en) | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
US5914131A (en) * | 1994-07-07 | 1999-06-22 | Alza Corporation | Hydromorphone therapy |
DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
CA2130410C (fr) | 1994-08-18 | 2001-12-04 | Albert John Kerklaan | Plot de connexion retractable |
US6491945B1 (en) | 1994-09-16 | 2002-12-10 | Alza Corporation | Hydrocodone therapy |
US5516808A (en) | 1994-10-27 | 1996-05-14 | Sawaya; Assad S. | Topical cellulose pharmaceutical formulation |
US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
DE4446470A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von teilbaren Tabletten |
US5585115A (en) | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
US5945125A (en) * | 1995-02-28 | 1999-08-31 | Temple University | Controlled release tablet |
US5695781A (en) | 1995-03-01 | 1997-12-09 | Hallmark Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers |
US6348469B1 (en) | 1995-04-14 | 2002-02-19 | Pharma Pass Llc | Solid compositions containing glipizide and polyethylene oxide |
US6117453A (en) | 1995-04-14 | 2000-09-12 | Pharma Pass | Solid compositions containing polyethylene oxide and an active ingredient |
ATE214596T1 (de) | 1995-04-14 | 2002-04-15 | Pharma Pass | Feste zusammensetzungen mit einem nicht-amorphem wirkstoff und polyäthylenoxyd |
US5654005A (en) | 1995-06-07 | 1997-08-05 | Andrx Pharmaceuticals, Inc. | Controlled release formulation having a preformed passageway |
US5634702A (en) | 1995-09-27 | 1997-06-03 | Fistonich; Juraj | Hands free waste container having a closed cover that automatically opens when the container is moved outside its cabinet enclosure |
GB9523752D0 (en) * | 1995-11-21 | 1996-01-24 | Pfizer Ltd | Pharmaceutical formulations |
DE19547766A1 (de) | 1995-12-20 | 1997-06-26 | Gruenenthal Gmbh | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe |
US5783212A (en) | 1996-02-02 | 1998-07-21 | Temple University--of the Commonwealth System of Higher Education | Controlled release drug delivery system |
ES2168610T3 (es) | 1996-03-12 | 2002-06-16 | Alza Corp | Composicion y forma galenica que contiene un antagonista opioide. |
US6461644B1 (en) | 1996-03-25 | 2002-10-08 | Richard R. Jackson | Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods |
US20020114838A1 (en) * | 1996-04-05 | 2002-08-22 | Ayer Atul D. | Uniform drug delivery therapy |
US6096339A (en) * | 1997-04-04 | 2000-08-01 | Alza Corporation | Dosage form, process of making and using same |
DE69723248T2 (de) | 1996-04-10 | 2004-05-27 | Warner-Lambert Co. Llc | Vergällungsstoffe für sympathomimetische aminsalze |
US5886164A (en) * | 1996-04-15 | 1999-03-23 | Zeneca Limited | DNA encoding enzymes related to ethylene biosynthesis and ripening from banana |
US20040024006A1 (en) * | 1996-05-06 | 2004-02-05 | Simon David Lew | Opioid pharmaceutical compositions |
GB9611328D0 (en) | 1996-05-31 | 1996-08-07 | Zeneca Ltd | Pharmaceutical compositions |
WO1997045091A2 (fr) | 1996-05-31 | 1997-12-04 | Euro-Celtique, S.A. | Formulations d'oxycodone a liberation prolongee sans effet sur l'etat alimente/a jeun |
US5955096A (en) | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
DE09003265T1 (de) | 1996-06-26 | 2010-04-29 | Board of Regents, The University of Texas System, Austin | Extrudierbare pharmazeutische Schmelzklebstoffformulierung |
US5730564A (en) | 1996-07-24 | 1998-03-24 | Illinois Tool Works Inc. | Cargo load supporting air bag having inflation indicating means, and method of determining proper inflation for spaced loads |
DE19630236A1 (de) | 1996-07-26 | 1998-01-29 | Wolff Walsrode Ag | Biaxial gereckte, biologisch abbaubare und kompostierbare Wursthülle |
US5869669A (en) | 1996-07-26 | 1999-02-09 | Penick Corporation | Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates |
BE1010353A5 (fr) | 1996-08-14 | 1998-06-02 | Boss Pharmaceuticals Ag | Procede pour la fabrication de produits pharmaceutiques, dispositif pour un tel procede et produits pharmaceutiques ainsi obtenus. |
JP4034357B2 (ja) | 1996-11-05 | 2008-01-16 | ノバモント・ソシエタ・ペル・アチオニ | デンプンと熱可塑性ポリマーからなる生分解性ポリマー組成物 |
US6919373B1 (en) * | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
US5948787A (en) | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
FR2761605B1 (fr) | 1997-04-07 | 2001-02-23 | Prographarm Lab | Forme pharmaceutique multiparticulaire, ses particules constitutives, procede et installation pour leur fabrication |
US6635280B2 (en) | 1997-06-06 | 2003-10-21 | Depomed, Inc. | Extending the duration of drug release within the stomach during the fed mode |
EP0998271B3 (fr) * | 1997-06-06 | 2014-10-29 | Depomed, Inc. | Formes de dosage de medicaments administres par voie orale a retention gastrique pour liberation lente de medicaments hautement solubles |
IL121038A0 (en) | 1997-06-09 | 1997-11-20 | Technion Res & Dev Foundation | A pharmaceutical composition for lowering glucose level in blood |
DE19724181A1 (de) | 1997-06-09 | 1998-12-10 | Bayer Ag | Multiple-unit-retard-Zubereitungen und Verfahren zu ihrer Herstellung |
WO1998056359A2 (fr) | 1997-06-13 | 1998-12-17 | Roland Bodmeier | Compositions retardant la liberation de principes actifs |
GB9713703D0 (en) | 1997-06-30 | 1997-09-03 | Johnson Matthey Plc | Preparation of opiates |
DK1009387T3 (da) | 1997-07-02 | 2006-08-14 | Euro Celtique Sa | Stabiliserede tramadolformuleringer med langvarig frigivelse |
AU739974B2 (en) * | 1997-09-26 | 2001-10-25 | Magna Interior Systems Inc. | Fastener assembly for joining two interior panels |
US6066339A (en) | 1997-10-17 | 2000-05-23 | Elan Corporation, Plc | Oral morphine multiparticulate formulation |
DE19749724A1 (de) | 1997-11-11 | 1999-06-10 | Gruenenthal Gmbh | Verwendung einer Kombination aus Opioid und alpha-adrenergem Agonisten in Schmerzmitteln |
PT1033975E (pt) * | 1997-11-28 | 2002-07-31 | Knoll Ag | Processo para a preparacao de substancias biologicamente activas nao-cristalinas isentas de dissolventes |
DE19753534A1 (de) | 1997-12-03 | 1999-06-10 | Bayer Ag | Schnell kristallisierende, biologisch abbaubare Polyesteramide |
GB9726365D0 (en) | 1997-12-13 | 1998-02-11 | Ciba Sc Holding Ag | Compounds |
PT1685839E (pt) | 1997-12-22 | 2013-07-08 | Euro Celtique Sa | Forma de dosagem farmacêutica por via oral compreendendo uma combinação de um agonista opióide e de um antagonista opióide |
CA2314896C (fr) * | 1997-12-22 | 2005-09-13 | Euro-Celtique, S.A. | Procede prevenant l'abus des doses orales d'opioides |
NZ504834A (en) | 1997-12-22 | 2001-12-21 | Schering Corp | Tricyclic amide molecular dispersion composition with enhanced bioavailability |
US6375957B1 (en) * | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
DE19800698A1 (de) | 1998-01-10 | 1999-07-15 | Bayer Ag | Biologisch abbaubare Polyesteramide mit blockartig aufgebauten Polyester- und Polyamid-Segmenten |
US6251430B1 (en) * | 1998-02-04 | 2001-06-26 | Guohua Zhang | Water insoluble polymer based sustained release formulation |
EP0980894B1 (fr) | 1998-03-05 | 2004-06-23 | Mitsui Chemicals, Inc. | Composition a base d'acide polylactique et son film |
US6245357B1 (en) | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
DE19822979A1 (de) | 1998-05-25 | 1999-12-02 | Kalle Nalo Gmbh & Co Kg | Folie mit Stärke oder Stärkederivaten und Polyesterurethanen sowie Verfahren zu ihrer Herstellung |
EP0974343B1 (fr) | 1998-07-22 | 2004-09-29 | Pharma Pass II LLC | Procédé de préparation d'une composition solide contentant du metoprolol |
US6117452A (en) | 1998-08-12 | 2000-09-12 | Fuisz Technologies Ltd. | Fatty ester combinations |
DE19855440A1 (de) | 1998-12-01 | 2000-06-08 | Basf Ag | Verfahren zum Herstellen fester Darreichungsformen mittels Schmelzextrusion |
IE981008A1 (en) | 1998-12-02 | 2000-06-14 | Fuisz Internat Ltd | Microparticles Containing Water Insoluble Active Agents |
EP1005863A1 (fr) | 1998-12-04 | 2000-06-07 | Synthelabo | Formes galeniques a liberation controlee contenant un hypnotique a activite courte ou un sel de ce compose |
US6238697B1 (en) * | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
DE19901683B4 (de) | 1999-01-18 | 2005-07-21 | Grünenthal GmbH | Analgetikum mit kontrollierter Wirkstofffreisetzung |
US20030118641A1 (en) * | 2000-07-27 | 2003-06-26 | Roxane Laboratories, Inc. | Abuse-resistant sustained-release opioid formulation |
DE19940944B4 (de) * | 1999-08-31 | 2006-10-12 | Grünenthal GmbH | Retardierte, orale, pharmazeutische Darreichungsformen |
ATE279186T1 (de) | 1999-08-31 | 2004-10-15 | Gruenenthal Gmbh | Retardierte darreichungsform enthaltend tramadolsaccharinat |
US7807211B2 (en) | 1999-09-03 | 2010-10-05 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of an implantable medical device |
US6491683B1 (en) | 1999-09-07 | 2002-12-10 | Alza Corporation | Osmotic dosage form composed of an extruded polymer tube form |
US6177567B1 (en) * | 1999-10-15 | 2001-01-23 | Boehringer Ingelheim Chemicals, Inc. | Method for preparing oxycodone |
DE19960494A1 (de) * | 1999-12-15 | 2001-06-21 | Knoll Ag | Vorrichtung und Verfahren zum Herstellen von festen wirkstoffhaltigen Formen |
WO2001045644A2 (fr) | 1999-12-23 | 2001-06-28 | Combe International Ltd. | Dispositif a resine de scellement et procede de fabrication |
ECSP003314A (es) | 2000-01-11 | 2000-03-22 | Formulaciones medicamentosas retardadas que contienen una combinacion de un opioide y un - agonista | |
US6680070B1 (en) | 2000-01-18 | 2004-01-20 | Albemarle Corporation | Particulate blends and compacted products formed therefrom, and the preparation thereof |
HUP0204163A2 (hu) | 2000-02-08 | 2003-04-28 | Euro-Celtique S.A. | Opioid agonistát és antagonistát tartalmazó szabályozott leadású készítmény és eljárás az előállítására |
US6277409B1 (en) * | 2000-02-11 | 2001-08-21 | Mcneil-Ppc, Inc. | Protective coating for tablet |
DE10015479A1 (de) | 2000-03-29 | 2001-10-11 | Basf Ag | Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität |
US20010036943A1 (en) | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
DE10025947A1 (de) | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Wirkstoffkombination enthaltend Montirelin und eine Verbindung mit opioider Wirksamkeit |
DE10025948A1 (de) | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Wirkstoffkombination |
EP1285902A4 (fr) | 2000-05-29 | 2007-04-18 | Shionogi & Co | Procede de marquage au tritium |
US6488962B1 (en) | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
DE10036400A1 (de) | 2000-07-26 | 2002-06-06 | Mitsubishi Polyester Film Gmbh | Weiße, biaxial orientierte Polyesterfolie |
WO2002026928A1 (fr) | 2000-09-28 | 2002-04-04 | The Dow Chemical Company | Structures de composites polymeriques utilisees dans des systemes de liberation controlee |
AU2738302A (en) * | 2000-10-30 | 2002-05-15 | Euro Celtique Sa | Controlled release hydrocodone formulations |
US20020187192A1 (en) | 2001-04-30 | 2002-12-12 | Yatindra Joshi | Pharmaceutical composition which reduces or eliminates drug abuse potential |
UA81224C2 (uk) | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
US20030065002A1 (en) * | 2001-05-11 | 2003-04-03 | Endo Pharmaceuticals, Inc. | Abuse-resistant controlled-release opioid dosage form |
DE60216078T2 (de) * | 2001-05-11 | 2007-07-05 | Endo Pharmaceuticals Inc. | Opioid enthaltende arzneiform gegen missbrauch |
US20030064122A1 (en) | 2001-05-23 | 2003-04-03 | Endo Pharmaceuticals, Inc. | Abuse resistant pharmaceutical composition containing capsaicin |
CA2449519A1 (fr) | 2001-06-08 | 2002-12-19 | Endo Pharmaceuticals, Inc. | Formes posologiques a liberation controlee utilisant un polymere acrylique, et leur procede d'obtention |
US7968119B2 (en) | 2001-06-26 | 2011-06-28 | Farrell John J | Tamper-proof narcotic delivery system |
PL207748B1 (pl) * | 2001-07-06 | 2011-01-31 | Penwest Pharmaceuticals Company | Preparat o przedłużonym uwalnianiu zawierający oksymorfon oraz jego zastosowanie |
CA2456322A1 (fr) | 2001-08-06 | 2003-02-20 | Euro-Celtique, S.A. | Compositions et methodes destinees a prevenir l'abus d'opioides |
US7842307B2 (en) | 2001-08-06 | 2010-11-30 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent |
US7141250B2 (en) * | 2001-08-06 | 2006-11-28 | Euro-Celtique S.A. | Pharmaceutical formulation containing bittering agent |
US7157103B2 (en) * | 2001-08-06 | 2007-01-02 | Euro-Celtique S.A. | Pharmaceutical formulation containing irritant |
US20030068375A1 (en) * | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
US7144587B2 (en) * | 2001-08-06 | 2006-12-05 | Euro-Celtique S.A. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent |
US7332182B2 (en) * | 2001-08-06 | 2008-02-19 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant |
WO2003015531A2 (fr) | 2001-08-06 | 2003-02-27 | Thomas Gruber | Formulation pharmaceutique contenant un colorant |
CA2455420A1 (fr) | 2001-08-06 | 2003-02-20 | Euro-Celtique, S.A. | Compositions et procedes servant a empecher la surconsommation d'opioides |
US20030069318A1 (en) * | 2001-08-21 | 2003-04-10 | Wenbin Dang | Salts of analgesic substances in oil, and methods of making and using the same |
US6691698B2 (en) | 2001-09-14 | 2004-02-17 | Fmc Technologies Inc. | Cooking oven having curved heat exchanger |
US20030068276A1 (en) | 2001-09-17 | 2003-04-10 | Lyn Hughes | Dosage forms |
US20030092724A1 (en) | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
US20040253310A1 (en) * | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
EP1429735A2 (fr) | 2001-09-26 | 2004-06-23 | Klaus-Jürgen Steffens | Procede et dispositif de production de granules comprenant au moins un principe actif pharmaceutique |
JP2005508325A (ja) | 2001-09-28 | 2005-03-31 | マクニール−ピーピーシー・インコーポレイテッド | 内側コア及び外側シェルを有する投薬形態 |
US20030229158A1 (en) | 2001-09-28 | 2003-12-11 | Chen Jen Chi | Polymer composition and dosage forms comprising the same |
US6982094B2 (en) | 2001-09-28 | 2006-01-03 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
PE20030527A1 (es) | 2001-10-24 | 2003-07-26 | Gruenenthal Chemie | Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen |
US20030152622A1 (en) * | 2001-10-25 | 2003-08-14 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral diuretic |
US20030104052A1 (en) * | 2001-10-25 | 2003-06-05 | Bret Berner | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
US6723340B2 (en) * | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
CA2409552A1 (fr) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Forme posologique orale pouvant etre retenue dans l'estomac dont la liberation est limitee a la partie inferieure du tube digestif |
US20030091630A1 (en) * | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
US20040126428A1 (en) * | 2001-11-02 | 2004-07-01 | Lyn Hughes | Pharmaceutical formulation including a resinate and an aversive agent |
FR2833838B1 (fr) | 2001-12-21 | 2005-09-16 | Ellipse Pharmaceuticals | Procede de fabrication d'un comprime incluant un analgesique de type morphinique et comprime obtenu |
US20030161882A1 (en) * | 2002-02-01 | 2003-08-28 | Waterman Kenneth C. | Osmotic delivery system |
DK1476138T3 (da) | 2002-02-21 | 2012-02-20 | Valeant Internat Barbados Srl | Formuleringer med modificeret frigivelse af mindst én form af tramadol |
GB0204772D0 (en) | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Pharmaceutical dosage forms |
DE10217232B4 (de) * | 2002-04-18 | 2004-08-19 | Ticona Gmbh | Verfahren zur Herstellung gefüllter Granulate aus Polyethylenen hohen bzw. ultrahohen Molekulargewichts |
US20050106249A1 (en) * | 2002-04-29 | 2005-05-19 | Stephen Hwang | Once-a-day, oral, controlled-release, oxycodone dosage forms |
CN1665482A (zh) * | 2002-04-29 | 2005-09-07 | 阿尔扎公司 | 羟可待酮控制输送给药的方法和剂型 |
AU2003234395B2 (en) | 2002-05-13 | 2008-01-24 | Endo Pharmaceuticals Inc. | Abuse-resistant opioid solid dosage form |
WO2003097608A2 (fr) * | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Composes opioides et de type opioide et leurs utilisations |
WO2003101384A2 (fr) | 2002-05-31 | 2003-12-11 | Alza Corporation | Formes galeniques et compositions d'administration osmotique de diverses posologies de l'oxycodone |
US7776314B2 (en) * | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10250083A1 (de) | 2002-06-17 | 2003-12-24 | Gruenenthal Gmbh | Gegen Missbrauch gesicherte Darreichungsform |
CA2491572C (fr) * | 2002-07-05 | 2010-03-23 | Collegium Pharmaceutical, Inc. | Compositions pharmaceutiques empechant la consommation abusive d'opioides et d'autres drogues |
US20040011806A1 (en) * | 2002-07-17 | 2004-01-22 | Luciano Packaging Technologies, Inc. | Tablet filler device with star wheel |
JP2005538105A (ja) | 2002-07-25 | 2005-12-15 | ファルマシア・コーポレーション | 水不溶性ポリマーおよび水溶性の小孔形成物質からなる2層により被覆された固体剤形の製造方法 |
CA2495182A1 (fr) | 2002-08-15 | 2004-02-26 | Noramco, Inc. | Polymorhes d'oxycodone-hydrochlorure |
EP1539098B1 (fr) | 2002-09-20 | 2011-08-10 | Fmc Corporation | Composition cosmetique contenant de la cellulose microcristalline |
CA2499994C (fr) | 2002-09-23 | 2012-07-10 | Verion, Inc. | Compositions pharmaceutiques n'induisant pas l'abus |
BR0314787A (pt) * | 2002-09-28 | 2005-07-26 | Mcneil Ppc Inc | Forma de dosagem de liberação modificada |
DE10250088A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE10250084A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE10250087A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US8487002B2 (en) | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
US20040110781A1 (en) | 2002-12-05 | 2004-06-10 | Harmon Troy M. | Pharmaceutical compositions containing indistinguishable drug components |
US20040185097A1 (en) | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
CA2519556C (fr) | 2003-04-21 | 2011-01-18 | Benjamin Oshlack | Forme posologique inviolable contenant des particules co-extrudees d'agent repulsif contraire et procede de fabrication |
CL2004000927A1 (es) | 2003-04-30 | 2005-01-28 | Purdue Pharma Lp | Forma de dosificacion transdermica que comprende un agente activo, una superficie proxima y una superficie distal. |
US20060251724A1 (en) | 2003-05-06 | 2006-11-09 | Farrell Thomas P | Method for preparing thermoformed compositions containing acrylic polymer binders, pharmaceutical dosage forms and methods of preparing the same |
US20040241234A1 (en) | 2003-06-02 | 2004-12-02 | Alpharma, Inc. | Controlled release press-coated formulations of water-soluble active agents |
US6864370B1 (en) * | 2003-06-05 | 2005-03-08 | Zhaiwei Lin | Process for manufacturing oxycodone |
TWI357815B (en) | 2003-06-27 | 2012-02-11 | Euro Celtique Sa | Multiparticulates |
US20050031655A1 (en) | 2003-08-04 | 2005-02-10 | Schering Plough Healthcare Products, Inc. | Emulsion composition |
DE102004020220A1 (de) | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
CA2534925A1 (fr) * | 2003-08-06 | 2005-02-24 | Gruenenthal Gmbh | Forme de preparation securisee contre un emploi abusif |
DE10361596A1 (de) * | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE102004032051A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US20070048228A1 (en) * | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
US20050089570A1 (en) * | 2003-09-26 | 2005-04-28 | Evangeline Cruz | Oros push-stick for controlled delivery of active agents |
CA2541371C (fr) | 2003-10-03 | 2014-12-16 | Atul M. Mehta | Formulations d'opioides a liberation prolongee et methode d'utilisation des formulations |
EP1677798A2 (fr) | 2003-10-29 | 2006-07-12 | Alza Corporation | Formes posologiques orales d'oxycodone en dose quotidienne unique et a liberation controlee |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
WO2005070760A1 (fr) | 2004-01-23 | 2005-08-04 | Antoine Sakellarides | Systeme amortisseur pour dame de nage de bateau a rame |
WO2005079752A2 (fr) | 2004-02-11 | 2005-09-01 | Rubicon Research Private Limited | Compositions pharmaceutiques a liberation controlee presentant une meilleure biodisponibilite |
TWI350762B (en) | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
TW201509943A (zh) * | 2004-03-30 | 2015-03-16 | Euro Celtique Sa | 含有小於25ppm14-羥可待因酮之羥可酮鹽酸鹽之組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝 |
WO2005102286A1 (fr) * | 2004-04-22 | 2005-11-03 | Grünenthal GmbH | Procede de production d'une forme galenique solide protegee contre un usage detourne |
JP2006002886A (ja) * | 2004-06-18 | 2006-01-05 | Noriatsu Kojima | 排水管 |
JP2006002884A (ja) * | 2004-06-18 | 2006-01-05 | Mitsubishi Plastics Ind Ltd | 連結具 |
WO2006002286A1 (fr) * | 2004-06-22 | 2006-01-05 | Magna International Inc. | Moulage d'etancheite d'automobile |
PL1765303T5 (pl) | 2004-07-01 | 2023-05-22 | Grünenthal GmbH | Tabletka doustna zabezpieczona przed nadużywaniem |
AR049839A1 (es) | 2004-07-01 | 2006-09-06 | Gruenenthal Gmbh | Procedimiento para la produccion deuna forma farmaceutica solida, protegida frente al abuso |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
AR053304A1 (es) | 2004-07-01 | 2007-05-02 | Gruenenthal Gmbh | Formas farmaceuticas orales protegidas frente al abuso con liberacion controlada de (1r,2r)-3-(3 dimetilamino-1-etil-2metil-propil)fenol y procedimiento para su produccion. |
GB0421149D0 (en) | 2004-09-23 | 2004-10-27 | Johnson Matthey Plc | Preparation of oxycodone |
MX2007009162A (es) | 2005-01-28 | 2007-10-23 | Euro Celtique Sa | Formas de dosis rsistente al alcohol. |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US20080274183A1 (en) | 2005-02-04 | 2008-11-06 | Phillip Michael Cook | Thermoplastic articles containing a medicament |
US7732427B2 (en) | 2005-03-31 | 2010-06-08 | University Of Delaware | Multifunctional and biologically active matrices from multicomponent polymeric solutions |
BRPI0612802A2 (pt) * | 2005-07-07 | 2010-11-30 | Farnam Co Inc | composições farmacêuticas de liberação sustentada para medicamentos extremamente hidrossolúveis |
US20070092573A1 (en) | 2005-10-24 | 2007-04-26 | Laxminarayan Joshi | Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist |
PL116330U1 (en) | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
US20070117826A1 (en) * | 2005-11-23 | 2007-05-24 | Forest Laboratories, Inc. | Pharmaceutical formulations comprising ibuprofen, oxycodone, and 14-hydroxycodeinone |
US20090022798A1 (en) | 2007-07-20 | 2009-01-22 | Abbott Gmbh & Co. Kg | Formulations of nonopioid and confined opioid analgesics |
US20070212414A1 (en) | 2006-03-08 | 2007-09-13 | Penwest Pharmaceuticals Co. | Ethanol-resistant sustained release formulations |
US7778314B2 (en) | 2006-05-04 | 2010-08-17 | Texas Instruments Incorporated | Apparatus for and method of far-end crosstalk (FEXT) detection and estimation |
SA07280459B1 (ar) * | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
EP2121699B1 (fr) | 2006-12-04 | 2012-09-19 | Noramco, Inc. | Procédé de préparation d'oxycodone présentant des taux réduits de 14-hydroxycodéinone |
PE20081632A1 (es) | 2007-01-12 | 2008-12-10 | Wyeth Corp | Composiciones de tableta en tableta |
EP2104493A2 (fr) | 2007-01-16 | 2009-09-30 | Egalet A/S | Utilisation (i) d'un polyglycol et (ii) d'une substance médicamenteuse active dans la préparation d'une composition pharmaceutique destinée (i) à réduire le risque de libération massive induite par l'alcool et/ou (ii) à réduire le risque de toxicomanie médicamenteuse |
GB2450691A (en) | 2007-07-02 | 2009-01-07 | Alpharma Aps | One-pot preparation of oxycodone from thebaine |
EP2262484B1 (fr) | 2008-03-11 | 2013-01-23 | Depomed, Inc. | Formes médicamenteuses à libération étendue de rétention gastrique comprenant des combinaisons d'un analgésique non opioïde et d'un analgésique opioïde |
US8671872B2 (en) | 2009-02-16 | 2014-03-18 | Thomas Engineering Inc. | Production coater with exchangeable drums |
KR101738369B1 (ko) * | 2009-07-22 | 2017-05-22 | 그뤼넨탈 게엠베하 | 핫 멜트 압출된 제어 방출 투여형 |
US9492492B2 (en) * | 2010-12-17 | 2016-11-15 | Johnson & Johnson Consumer Inc. | Compositions comprising Lilium martagon extracts and uses thereof |
EP2826468A1 (fr) * | 2010-12-22 | 2015-01-21 | Purdue Pharma L.P. | Formes posologiques à libération contrôlée enchâssées et inviolables |
US9846413B2 (en) * | 2011-09-08 | 2017-12-19 | Fire Avert, Llc. | Safety shut-off device and method of use |
US10764498B2 (en) * | 2017-03-22 | 2020-09-01 | Canon Kabushiki Kaisha | Image processing apparatus, method of controlling the same, and storage medium |
US10764499B2 (en) * | 2017-06-16 | 2020-09-01 | Microsoft Technology Licensing, Llc | Motion blur detection |
-
2007
- 2007-08-22 SA SA7280459A patent/SA07280459B1/ar unknown
- 2007-08-23 JO JO2007345A patent/JO2858B1/en active
- 2007-08-24 PT PT10192644T patent/PT2292230E/pt unknown
- 2007-08-24 PT PT111569976T patent/PT2343071E/pt unknown
- 2007-08-24 DE DE602007002596T patent/DE602007002596D1/de active Active
- 2007-08-24 KR KR1020177029318A patent/KR20170118249A/ko not_active Application Discontinuation
- 2007-08-24 ES ES11157006T patent/ES2417334T3/es active Active
- 2007-08-24 PL PL09156843T patent/PL2082742T3/pl unknown
- 2007-08-24 SI SI200731010T patent/SI2311459T1/sl unknown
- 2007-08-24 ES ES10192627T patent/ES2390419T3/es active Active
- 2007-08-24 ES ES11156997T patent/ES2411695T3/es active Active
- 2007-08-24 ME MEP-2011-27A patent/ME01339B/fr unknown
- 2007-08-24 ES ES10192644T patent/ES2388615T3/es active Active
- 2007-08-24 ME MEP-2009-348A patent/ME01064B/fr unknown
- 2007-08-24 SI SI200731241T patent/SI2399580T1/sl unknown
- 2007-08-24 EP EP09156832A patent/EP2070538B1/fr active Active
- 2007-08-24 ES ES10192641T patent/ES2388591T3/es active Active
- 2007-08-24 DE DE602007010974T patent/DE602007010974D1/de active Active
- 2007-08-24 SI SI200731243T patent/SI2343071T1/sl unknown
- 2007-08-24 AT AT09156832T patent/ATE489953T1/de active
- 2007-08-24 CN CN2012101965722A patent/CN102688213A/zh active Pending
- 2007-08-24 PT PT111570131T patent/PT2399580E/pt unknown
- 2007-08-24 DK DK09156838.6T patent/DK2080514T3/da active
- 2007-08-24 CN CN201710126802.0A patent/CN107412179B/zh active Active
- 2007-08-24 AR ARP070103759A patent/AR062511A1/es not_active Application Discontinuation
- 2007-08-24 ES ES07114982T patent/ES2334466T3/es active Active
- 2007-08-24 PE PE2015000012A patent/PE20150340A1/es active IP Right Grant
- 2007-08-24 PT PT111570065T patent/PT2399579E/pt unknown
- 2007-08-24 PL PL11156997T patent/PL2343071T3/pl unknown
- 2007-08-24 SI SI200730513T patent/SI2070538T1/sl unknown
- 2007-08-24 SI SI200730120T patent/SI1897545T1/sl unknown
- 2007-08-24 RS RS20130244A patent/RS52798B/en unknown
- 2007-08-24 NZ NZ574447A patent/NZ574447A/en unknown
- 2007-08-24 DK DK10192641.8T patent/DK2292229T3/da active
- 2007-08-24 PL PL09156838T patent/PL2080514T3/pl unknown
- 2007-08-24 EP EP11156997A patent/EP2343071B1/fr active Active
- 2007-08-24 CN CN201210135209.XA patent/CN102657630B/zh not_active Ceased
- 2007-08-24 DK DK11156997.6T patent/DK2343071T3/da active
- 2007-08-24 SI SI200730982T patent/SI2292229T1/sl unknown
- 2007-08-24 EP EP11157013A patent/EP2399580B1/fr active Active
- 2007-08-24 DK DK11157013.1T patent/DK2399580T3/da active
- 2007-08-24 PL PL09156832T patent/PL2070538T3/pl unknown
- 2007-08-24 PL PL11157006T patent/PL2399579T3/pl unknown
- 2007-08-24 KR KR1020147008575A patent/KR101568100B1/ko active IP Right Grant
- 2007-08-24 AP AP2009004770A patent/AP2009004770A0/xx unknown
- 2007-08-24 WO PCT/IB2007/002515 patent/WO2008023261A1/fr active Application Filing
- 2007-08-24 SI SI200731242T patent/SI2399579T1/sl unknown
- 2007-08-24 EP EP09156838A patent/EP2080514B1/fr active Active
- 2007-08-24 ME MEP-2013-58A patent/ME01550B/me unknown
- 2007-08-24 CN CN201510599504.4A patent/CN105213345B/zh active Active
- 2007-08-24 RS RS20110058A patent/RS51591B/en unknown
- 2007-08-24 UA UAA201107825A patent/UA104745C2/ru unknown
- 2007-08-24 JP JP2009525126A patent/JP5069300B2/ja active Active
- 2007-08-24 RS RS20130223A patent/RS52793B/en unknown
- 2007-08-24 PE PE2007001153A patent/PE20080765A1/es active IP Right Grant
- 2007-08-24 DK DK09156832.9T patent/DK2070538T3/da active
- 2007-08-24 RS RS20110171A patent/RS51664B/en unknown
- 2007-08-24 AU AU2007287341A patent/AU2007287341B2/en active Active
- 2007-08-24 PE PE2009000362A patent/PE20091184A1/es active IP Right Grant
- 2007-08-24 PT PT07114982T patent/PT1897545E/pt unknown
- 2007-08-24 DK DK07114982.7T patent/DK1897545T3/da active
- 2007-08-24 ME MEP-2012-105A patent/ME01482B/me unknown
- 2007-08-24 KR KR1020127021463A patent/KR101455914B1/ko active IP Right Grant
- 2007-08-24 BR BRPI0714539A patent/BRPI0714539B8/pt active IP Right Grant
- 2007-08-24 CA CA2661573A patent/CA2661573C/fr active Active
- 2007-08-24 EA EA201171403A patent/EA023807B1/ru not_active IP Right Cessation
- 2007-08-24 PL PL10192641T patent/PL2292229T3/pl unknown
- 2007-08-24 KR KR1020167022072A patent/KR101787605B1/ko active IP Right Grant
- 2007-08-24 DK DK10192644.2T patent/DK2292230T3/da active
- 2007-08-24 ME MEP-2011-26A patent/ME01255B/fr unknown
- 2007-08-24 EP EP07114982A patent/EP1897545B1/fr active Active
- 2007-08-24 MX MX2013014243A patent/MX360849B/es unknown
- 2007-08-24 DE DE602007012747T patent/DE602007012747D1/de active Active
- 2007-08-24 ES ES11157013T patent/ES2417335T3/es active Active
- 2007-08-24 MY MYPI2012004970A patent/MY161079A/en unknown
- 2007-08-24 PL PL11157003T patent/PL2384754T3/pl unknown
- 2007-08-24 RS RSP-2009/0536A patent/RS51162B/sr unknown
- 2007-08-24 PT PT10192641T patent/PT2292229E/pt unknown
- 2007-08-24 CL CL2007002485A patent/CL2007002485A1/es unknown
- 2007-08-24 RS RS20120328A patent/RS52402B/en unknown
- 2007-08-24 CN CN201510599477.0A patent/CN105267170B/zh not_active Ceased
- 2007-08-24 ES ES11157003T patent/ES2411696T3/es active Active
- 2007-08-24 PE PE2019000935A patent/PE20191048A1/es unknown
- 2007-08-24 PL PL07114982T patent/PL1897545T3/pl unknown
- 2007-08-24 KR KR1020157017047A patent/KR101649838B1/ko active Application Filing
- 2007-08-24 RS RS20120394A patent/RS52463B/en unknown
- 2007-08-24 DE DE202007011825U patent/DE202007011825U1/de not_active Expired - Lifetime
- 2007-08-24 ES ES09156843T patent/ES2358066T3/es active Active
- 2007-08-24 BR BR122016004010A patent/BR122016004010B8/pt active IP Right Grant
- 2007-08-24 ME MEP-2013-67A patent/ME01580B/me unknown
- 2007-08-24 RS RS20130200A patent/RS52779B/en unknown
- 2007-08-24 CN CN201210196662.1A patent/CN102743355B/zh active Active
- 2007-08-24 CN CN200780031610.6A patent/CN101583360B/zh active Active
- 2007-08-24 MY MYPI20090749A patent/MY146650A/en unknown
- 2007-08-24 TW TW096131511A patent/TWI341213B/zh active
- 2007-08-24 EA EA200900343A patent/EA018311B1/ru not_active IP Right Cessation
- 2007-08-24 DK DK11157006.5T patent/DK2399579T3/da active
- 2007-08-24 PL PL11157013T patent/PL2399580T3/pl unknown
- 2007-08-24 PL PL10192627T patent/PL2311459T3/pl unknown
- 2007-08-24 PT PT09156843T patent/PT2082742E/pt unknown
- 2007-08-24 PT PT111570032T patent/PT2384754E/pt unknown
- 2007-08-24 EP EP10192644A patent/EP2292230B1/fr active Active
- 2007-08-24 NZ NZ597760A patent/NZ597760A/xx unknown
- 2007-08-24 ES ES09156838T patent/ES2361721T3/es active Active
- 2007-08-24 ME MEP-2011-79A patent/ME01187B/fr unknown
- 2007-08-24 DE DE602007010963T patent/DE602007010963D1/de active Active
- 2007-08-24 PT PT09156832T patent/PT2070538E/pt unknown
- 2007-08-24 EP EP10192641A patent/EP2292229B1/fr active Active
- 2007-08-24 DK DK09156843.6T patent/DK2082742T3/da active
- 2007-08-24 CA CA2707204A patent/CA2707204C/fr active Active
- 2007-08-24 SI SI200730563T patent/SI2080514T1/sl unknown
- 2007-08-24 AT AT09156838T patent/ATE499101T1/de active
- 2007-08-24 AT AT07114982T patent/ATE444070T1/de active
- 2007-08-24 RS RS20110056A patent/RS51678B/en unknown
- 2007-08-24 RS RS20130265A patent/RS52813B/en unknown
- 2007-08-24 IN IN1813DEN2015 patent/IN2015DN01813A/en unknown
- 2007-08-24 EP EP11157003A patent/EP2384754B1/fr active Active
- 2007-08-24 MX MX2009002023A patent/MX2009002023A/es active IP Right Grant
- 2007-08-24 EA EA201300465A patent/EA031873B1/ru not_active IP Right Cessation
- 2007-08-24 PE PE2014000147A patent/PE20140854A1/es active IP Right Grant
- 2007-08-24 CN CN201410024630.2A patent/CN103861111B/zh active Active
- 2007-08-24 EP EP10192627A patent/EP2311459B1/fr active Active
- 2007-08-24 KR KR1020097006064A patent/KR101205579B1/ko active IP Right Grant
- 2007-08-24 KR KR1020117024787A patent/KR101496510B1/ko active IP Right Grant
- 2007-08-24 ES ES09156832T patent/ES2357376T3/es active Active
- 2007-08-24 NZ NZ608651A patent/NZ608651A/en unknown
- 2007-08-24 MY MYPI20124957 patent/MY153092A/en unknown
- 2007-08-24 DK DK11157003.2T patent/DK2384754T3/da active
- 2007-08-24 EP EP11157006.5A patent/EP2399579B9/fr active Active
- 2007-08-24 SI SI200730989T patent/SI2292230T1/sl unknown
- 2007-08-24 US US11/844,872 patent/US8894987B2/en active Active
- 2007-08-24 DK DK10192627.7T patent/DK2311459T3/da active
- 2007-08-24 RS RS20120320A patent/RS52401B/en unknown
- 2007-08-24 KR KR1020127021462A patent/KR101514388B1/ko active IP Right Grant
- 2007-08-24 PT PT10192627T patent/PT2311459E/pt unknown
- 2007-08-24 UA UAA200902798A patent/UA96306C2/ru unknown
- 2007-08-24 EP EP09156843A patent/EP2082742B1/fr active Active
- 2007-08-24 AT AT09156843T patent/ATE489954T1/de active
- 2007-08-24 PT PT09156838T patent/PT2080514E/pt unknown
- 2007-08-24 PL PL10192644T patent/PL2292230T3/pl unknown
- 2007-08-24 SI SI200730512T patent/SI2082742T1/sl unknown
- 2007-08-24 SI SI200731244T patent/SI2384754T1/sl unknown
- 2007-08-24 CN CN201210196551.0A patent/CN102688241B/zh active Active
-
2008
- 2008-09-03 HK HK09111397.7A patent/HK1133192A1/xx unknown
- 2008-09-03 HK HK09112030.8A patent/HK1132189A1/xx unknown
- 2008-09-03 HK HK08109790.5A patent/HK1118225A1/xx unknown
- 2008-09-03 HK HK09112034.4A patent/HK1138498A1/xx unknown
-
2009
- 2009-02-02 ZA ZA200900755A patent/ZA200900755B/xx unknown
- 2009-02-05 GT GT200900023BA patent/GT200900023BA/es unknown
- 2009-02-05 GT GT200900023A patent/GT200900023A/es unknown
- 2009-02-24 IL IL197214A patent/IL197214A/en active IP Right Grant
- 2009-02-24 DO DO2009000026A patent/DOP2009000026A/es unknown
- 2009-02-25 TN TN2009000059A patent/TN2009000059A1/fr unknown
- 2009-03-19 CO CO09028553A patent/CO6160317A2/es unknown
- 2009-03-24 MA MA31733A patent/MA30766B1/fr unknown
- 2009-03-25 CR CR10691A patent/CR10691A/es unknown
- 2009-08-14 AT AT0050909U patent/AT11571U1/de not_active IP Right Cessation
- 2009-12-11 CY CY20091101293T patent/CY1110573T1/el unknown
- 2009-12-28 HR HR20090688T patent/HRP20090688T1/hr unknown
-
2011
- 2011-02-23 CY CY20111100220T patent/CY1111897T1/el unknown
- 2011-02-23 HR HR20110130T patent/HRP20110130T1/hr unknown
- 2011-02-23 CY CY20111100217T patent/CY1111887T1/el unknown
- 2011-02-28 HR HR20110147T patent/HRP20110147T1/hr unknown
- 2011-05-17 CY CY20111100472T patent/CY1111896T1/el unknown
- 2011-05-20 HR HR20110375T patent/HRP20110375T1/hr unknown
- 2011-08-05 DO DO2011000255A patent/DOP2011000255A/es unknown
- 2011-08-16 HK HK11108648.6A patent/HK1154491A1/xx unknown
- 2011-08-26 HK HK11109019.5A patent/HK1154788A1/xx unknown
- 2011-08-26 HK HK11109020.2A patent/HK1154789A1/xx unknown
- 2011-10-18 HK HK12106233.0A patent/HK1165317A1/xx unknown
- 2011-10-18 HK HK11111131.4A patent/HK1156845A1/xx unknown
- 2011-10-18 HK HK12106234.9A patent/HK1165318A1/xx unknown
- 2011-10-18 HK HK12106232.1A patent/HK1165316A1/xx unknown
-
2012
- 2012-01-26 IL IL217788A patent/IL217788A0/en active IP Right Grant
- 2012-01-26 IL IL217787A patent/IL217787A0/en active IP Right Grant
- 2012-01-26 IL IL217792A patent/IL217792A/en active IP Right Grant
- 2012-01-26 IL IL217794A patent/IL217794A/en active IP Right Grant
- 2012-01-26 IL IL217790A patent/IL217790A0/en active IP Right Grant
- 2012-01-26 IL IL217791A patent/IL217791A/en active IP Right Grant
- 2012-01-26 IL IL217789A patent/IL217789A0/en active IP Right Grant
- 2012-03-01 JP JP2012045261A patent/JP5373133B2/ja active Active
- 2012-04-19 JP JP2012096011A patent/JP2012167102A/ja not_active Withdrawn
- 2012-07-13 JP JP2012157159A patent/JP2012229250A/ja not_active Withdrawn
- 2012-07-13 JP JP2012157158A patent/JP2012229249A/ja not_active Withdrawn
- 2012-07-13 JP JP2012157157A patent/JP5642736B2/ja active Active
- 2012-07-25 HR HRP20120613TT patent/HRP20120613T1/hr unknown
- 2012-08-07 HR HRP20120641TT patent/HRP20120641T1/hr unknown
- 2012-08-20 HR HRP20120670TT patent/HRP20120670T1/hr unknown
- 2012-08-22 CY CY20121100749T patent/CY1113220T1/el unknown
- 2012-08-22 CY CY20121100750T patent/CY1113231T1/el unknown
- 2012-09-25 CY CY20121100874T patent/CY1113141T1/el unknown
-
2013
- 2013-03-14 US US13/803,132 patent/US20140030327A1/en not_active Abandoned
- 2013-05-17 HR HRP20130433TT patent/HRP20130433T1/hr unknown
- 2013-05-17 HR HRP20130434TT patent/HRP20130434T1/hr unknown
- 2013-05-22 HR HRP20130444TT patent/HRP20130444T1/hr unknown
- 2013-05-23 US US13/901,199 patent/US20130251801A1/en not_active Abandoned
- 2013-05-23 US US13/901,078 patent/US8815289B2/en active Active
- 2013-05-23 US US13/901,047 patent/US8846086B2/en active Active
- 2013-05-23 US US13/900,873 patent/US8821929B2/en active Active
- 2013-05-23 US US13/901,218 patent/US8911719B2/en active Active
- 2013-05-23 US US13/901,142 patent/US20130251800A1/en not_active Abandoned
- 2013-05-23 US US13/901,174 patent/US20130251797A1/en not_active Abandoned
- 2013-05-23 US US13/901,027 patent/US20130251796A1/en not_active Abandoned
- 2013-05-23 US US13/901,122 patent/US8834925B2/en active Active
- 2013-05-23 US US13/900,963 patent/US8894988B2/en active Active
- 2013-05-23 US US13/900,933 patent/US20130259938A1/en not_active Abandoned
- 2013-06-13 HR HRP20130539TT patent/HRP20130539T1/hr unknown
- 2013-09-26 US US14/038,209 patent/US20140024669A1/en not_active Abandoned
- 2013-09-27 US US14/040,535 patent/US8808741B2/en active Active
-
2014
- 2014-04-22 CL CL2014001029A patent/CL2014001029A1/es unknown
- 2014-07-16 CR CR20140340A patent/CR20140340A/es unknown
- 2014-10-16 US US14/515,924 patent/US9084816B2/en active Active
- 2014-10-16 US US14/515,921 patent/US9095615B2/en active Active
- 2014-10-16 US US14/515,857 patent/US9101661B2/en active Active
- 2014-10-16 US US14/515,855 patent/US9095614B2/en active Active
- 2014-10-23 JO JOP/2014/0306A patent/JO3323B1/ar active
- 2014-10-29 JP JP2014220816A patent/JP5980881B2/ja active Active
-
2015
- 2015-06-03 US US14/729,660 patent/US9492393B2/en active Active
- 2015-06-03 US US14/729,565 patent/US9492389B2/en active Active
- 2015-06-03 US US14/729,634 patent/US9492392B2/en active Active
- 2015-06-03 US US14/729,601 patent/US9492390B2/en active Active
- 2015-06-03 US US14/729,593 patent/US9486412B2/en active Active
- 2015-06-03 US US14/729,626 patent/US9492391B2/en active Active
- 2015-06-03 US US14/729,675 patent/US9486413B2/en active Active
- 2015-06-03 US US14/729,688 patent/US9545380B2/en active Active
- 2015-09-03 IL IL241121A patent/IL241121A/en active IP Right Grant
- 2015-09-03 IL IL241122A patent/IL241122B/en active IP Right Grant
-
2016
- 2016-01-21 AR ARP160100147A patent/AR103463A2/es not_active Application Discontinuation
- 2016-07-27 JP JP2016146843A patent/JP6286491B2/ja active Active
- 2016-09-13 US US15/263,932 patent/US9775812B2/en active Active
-
2017
- 2017-01-24 US US15/413,678 patent/US9770416B2/en active Active
- 2017-01-24 US US15/413,656 patent/US9775809B2/en active Active
- 2017-01-24 US US15/413,505 patent/US9763886B2/en active Active
- 2017-01-24 US US15/413,554 patent/US9775811B2/en active Active
- 2017-01-24 US US15/413,635 patent/US9775808B2/en active Active
- 2017-01-24 US US15/413,614 patent/US9763933B2/en active Active
- 2017-01-24 US US15/413,530 patent/US9775810B2/en active Active
- 2017-01-24 US US15/413,580 patent/US9770417B2/en active Active
- 2017-03-20 CL CL2017000669A patent/CL2017000669A1/es unknown
- 2017-05-17 US US15/597,885 patent/US20170246116A1/en not_active Abandoned
- 2017-07-24 US US15/657,643 patent/US20170319491A1/en not_active Abandoned
- 2017-07-24 US US15/657,424 patent/US20170319488A1/en not_active Abandoned
- 2017-07-24 US US15/657,793 patent/US20170319494A1/en not_active Abandoned
- 2017-07-24 US US15/657,895 patent/US20170319497A1/en not_active Abandoned
- 2017-07-24 US US15/657,521 patent/US20170319490A1/en not_active Abandoned
- 2017-07-24 US US15/657,852 patent/US20170319496A1/en not_active Abandoned
- 2017-07-24 US US15/657,916 patent/US20170319498A1/en not_active Abandoned
- 2017-07-24 US US15/657,491 patent/US20170319489A1/en not_active Abandoned
- 2017-07-24 US US15/657,818 patent/US20170319495A1/en not_active Abandoned
- 2017-07-24 US US15/657,599 patent/US20170354607A1/en not_active Abandoned
- 2017-07-24 US US15/657,761 patent/US20170319493A1/en not_active Abandoned
- 2017-07-24 US US15/657,717 patent/US20170319492A1/en not_active Abandoned
- 2017-08-22 US US15/683,472 patent/US20170348241A1/en not_active Abandoned
- 2017-08-22 US US15/683,436 patent/US20170348240A1/en not_active Abandoned
- 2017-10-04 AR ARP170102763A patent/AR109797A2/es not_active Application Discontinuation
- 2017-10-04 AR ARP170102762A patent/AR109796A2/es not_active Application Discontinuation
-
2018
- 2018-01-31 US US15/885,074 patent/US20180369150A1/en not_active Abandoned
- 2018-01-31 US US15/885,254 patent/US10076498B2/en active Active
- 2018-01-31 US US15/885,413 patent/US10076499B2/en active Active
- 2018-05-03 HK HK18105698.4A patent/HK1246175A1/zh unknown
- 2018-08-28 US US16/115,024 patent/US20190000767A1/en not_active Abandoned
-
2020
- 2020-07-17 US US16/931,803 patent/US20210169810A1/en not_active Abandoned
- 2020-09-21 US US17/027,088 patent/US11298322B2/en active Active
- 2020-09-21 US US17/027,222 patent/US11304908B2/en active Active
- 2020-09-21 US US17/027,307 patent/US11304909B2/en active Active
-
2022
- 2022-08-22 US US17/892,553 patent/US11904055B2/en active Active
-
2023
- 2023-05-05 US US18/143,927 patent/US11826472B2/en active Active
- 2023-06-05 US US18/205,786 patent/US11938225B2/en active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA30766B1 (fr) | Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide | |
MA51204B1 (fr) | Formes pharmaceutiques comprenant un inhibiteur de la kallicréine plasmatique | |
HRP20120004T1 (en) | Dipeptidyl peptidase inhibitors for treating diabetes | |
TW200833370A (en) | Pharmaceutical composition containing low substituted hydroxypropylcellulose | |
EA200900023A1 (ru) | Применение замещенных 2-аминотетралинов для изготовления лекарственного средства для предупреждения, облегчения и/или лечения разных видов боли | |
MA29734B1 (fr) | Formes posologiques solides de valsartan et d'amlodipine et procede de preparation afferent | |
MA30807B1 (fr) | Compositions pharmaceutiques. | |
MA35513B1 (fr) | Compositions pharmaceutiques comprenant 40 - o - ( 2 - hydroxy) éthyl - rapamycine | |
BRPI0509184A (pt) | composições farmacêuticas | |
IL193252A0 (en) | N-hydroxyacrylamide compounds | |
PL415001A1 (pl) | Kompozycje farmaceutyczne zawierające kwas mykofenolowy lub sól mykofenolanową | |
BRPI0519198A2 (pt) | moduladores de delta-opiàide tricÍclicos | |
MA33679B1 (fr) | Derives de 2-oxo-1-pyrrolidinyle imidazothiadiazole | |
EA201001108A1 (ru) | Диспергируемые во рту таблетки, содержащие основание эсциталопрама, и способ их получения | |
BRPI0509014A (pt) | comprimidos desintegráveis que compreendem licarbazepina | |
BRPI0410044A (pt) | forma de dosagem contendo pantoprazol como ingrediente ativo | |
ATE451385T1 (de) | Verbindungen zur inhibierung von apoptose | |
EP2101742B8 (fr) | Composition pharmaceutique contenant de l'hydrogénosulfate de clopidogrel de forme polymorphe 1 | |
FR2898059B1 (fr) | Composition phytohormonale contenant de la sauge | |
NO20044900L (no) | Progestagene doseringsenheter | |
MA31950B1 (fr) | Composition pharmaceutique | |
EA201000118A1 (ru) | Сублингвальные или трансбуккальные композиции, содержащие янтарную кислоту и предназначенные для лечения болезни альцгеймера | |
RU2008132511A (ru) | Способ лечения гипертензивных внутримозговых кровоизлияний | |
MA30482B1 (fr) | Sels et leurs modification cristallines | |
ECSP024344A (es) | Composiciones farmaceuticas |