JP2021006028A5 - - Google Patents
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- JP2021006028A5 JP2021006028A5 JP2020135592A JP2020135592A JP2021006028A5 JP 2021006028 A5 JP2021006028 A5 JP 2021006028A5 JP 2020135592 A JP2020135592 A JP 2020135592A JP 2020135592 A JP2020135592 A JP 2020135592A JP 2021006028 A5 JP2021006028 A5 JP 2021006028A5
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1321196.6 | 2013-12-02 | ||
| GB1321196.6A GB2520765A (en) | 2013-12-02 | 2013-12-02 | Multiplex detection of nucleic acids |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535001A Division JP6749236B2 (ja) | 2013-12-02 | 2014-11-26 | 核酸の多重検出 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021006028A JP2021006028A (ja) | 2021-01-21 |
| JP2021006028A5 true JP2021006028A5 (https=) | 2021-04-22 |
| JP7091400B2 JP7091400B2 (ja) | 2022-06-27 |
Family
ID=49979622
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535001A Active JP6749236B2 (ja) | 2013-12-02 | 2014-11-26 | 核酸の多重検出 |
| JP2020135592A Active JP7091400B2 (ja) | 2013-12-02 | 2020-08-11 | 核酸の多重検出 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535001A Active JP6749236B2 (ja) | 2013-12-02 | 2014-11-26 | 核酸の多重検出 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10526643B2 (https=) |
| EP (2) | EP3757228B1 (https=) |
| JP (2) | JP6749236B2 (https=) |
| KR (2) | KR102451174B1 (https=) |
| CN (1) | CN105934523B (https=) |
| AU (1) | AU2014358862B2 (https=) |
| BR (1) | BR112016012319B1 (https=) |
| CA (1) | CA2931015C (https=) |
| ES (2) | ES2987069T3 (https=) |
| GB (1) | GB2520765A (https=) |
| RU (1) | RU2733887C2 (https=) |
| WO (1) | WO2015083002A2 (https=) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3013983B1 (en) | 2013-06-25 | 2023-02-15 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| GB2520763A (en) | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Nucleic acid probe and method of detecting genomic fragments |
| GB2520765A (en) | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Multiplex detection of nucleic acids |
| KR102535489B1 (ko) | 2014-06-13 | 2023-05-22 | 큐-리네아 에이비 | 미생물 검출 방법 및 특성 규명 방법 |
| US10774374B2 (en) | 2015-04-10 | 2020-09-15 | Spatial Transcriptomics AB and Illumina, Inc. | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| GB201507026D0 (en) | 2015-04-24 | 2015-06-10 | Linea Ab Q | Medical sample transportation container |
| GB201507376D0 (en) | 2015-04-30 | 2015-06-17 | Vanadis Diagnostics Ab | Use of a porous transparent capillary membrane for counting rolling circle amplification products |
| KR102753113B1 (ko) | 2015-09-18 | 2025-01-09 | 바나디스 다이아그노스틱스 | Dna 샘플의 분석을 위한 프로브 세트 및 이의 사용 방법 |
| GB2554767A (en) | 2016-04-21 | 2018-04-11 | Q Linea Ab | Detecting and characterising a microorganism |
| CN110023505B (zh) | 2016-10-27 | 2023-04-04 | 瓦纳迪斯诊断公司 | 用于处理滚环扩增产物的方法 |
| GB201621514D0 (en) | 2016-12-16 | 2017-02-01 | Q-Linea Ab | Padlock probe detection method |
| CN106929593B (zh) * | 2017-04-27 | 2021-04-30 | 华侨大学 | 一种原位核酸检测方法 |
| CN109252224A (zh) * | 2017-07-14 | 2019-01-22 | 深圳华大基因股份有限公司 | 一种环状探针和基于环状探针捕获的测序文库构建方法 |
| US11117128B2 (en) | 2017-08-25 | 2021-09-14 | Vanadis Diagnostics Ab | Filtration device |
| WO2019195346A1 (en) | 2018-04-02 | 2019-10-10 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
| US12203129B2 (en) * | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| US12497649B2 (en) | 2018-12-05 | 2025-12-16 | Qingdao MGI Tech Co., Ltd | Rolling circle amplification method, method for preparing sequencing library, and DNA nanosphere prepared therefrom |
| EP3894590B1 (en) | 2018-12-10 | 2025-10-22 | 10X Genomics, Inc. | Methods of using master / copy arrays for spatial detection |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| EP3947718A4 (en) | 2019-04-02 | 2022-12-21 | Enumera Molecular, Inc. | METHODS, SYSTEMS AND COMPOSITIONS FOR COUNTING NUCLEIC ACID MOLECULES |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| US11639521B2 (en) * | 2019-06-03 | 2023-05-02 | The Chinese University Of Hong Kong | Method for determining the copy number of a tandem repeat sequence |
| WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| WO2021133849A1 (en) | 2019-12-23 | 2021-07-01 | 10X Genomics, Inc. | Methods for spatial analysis using rna-templated ligation |
| CN115135984B (zh) | 2019-12-23 | 2025-12-23 | 10X基因组学有限公司 | 可逆固定试剂及其使用方法 |
| EP4081656A1 (en) | 2019-12-23 | 2022-11-02 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| WO2021158925A1 (en) | 2020-02-07 | 2021-08-12 | 10X Genomics, Inc. | Quantitative and automated permeabilization performance evaluation for spatial transcriptomics |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| ES2965354T3 (es) | 2020-04-22 | 2024-04-12 | 10X Genomics Inc | Métodos para análisis espacial que usan eliminación de ARN elegido como diana |
| EP4153775B1 (en) | 2020-05-22 | 2024-07-24 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| EP4553168A3 (en) | 2020-05-22 | 2025-08-27 | 10x Genomics, Inc. | Spatial analysis to detect sequence variants |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| WO2021252733A2 (en) * | 2020-06-10 | 2021-12-16 | Bonadea Diagnostics, Llc | Sequence conversion reaction |
| EP4172362B1 (en) | 2020-06-25 | 2024-09-18 | 10X Genomics, Inc. | Spatial analysis of dna methylation |
| US12209280B1 (en) | 2020-07-06 | 2025-01-28 | 10X Genomics, Inc. | Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| CN116438454A (zh) | 2020-09-21 | 2023-07-14 | 普罗根尼蒂公司 | 用于分离细胞游离dna的组合物和方法 |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| EP4697281A3 (en) | 2020-12-11 | 2026-04-22 | Enumera Molecular, Inc. | Methods and systems for image processing |
| EP4729631A2 (en) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| EP4428246B1 (en) | 2021-04-14 | 2025-12-24 | 10X Genomics, Inc. | Methods of measuring mislocalization of an analyte |
| EP4320271B1 (en) | 2021-05-06 | 2025-03-19 | 10X Genomics, Inc. | Methods for increasing resolution of spatial analysis |
| EP4582555A3 (en) | 2021-06-03 | 2025-10-22 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| EP4352252B1 (en) * | 2021-07-13 | 2026-01-28 | 10X Genomics, Inc. | Methods for spatial analysis using targeted probe silencing |
| ES3011462T3 (en) | 2021-09-01 | 2025-04-07 | 10X Genomics Inc | Methods for blocking a capture probe on a spatial array |
| CN113801923A (zh) * | 2021-10-20 | 2021-12-17 | 南京鼓楼医院 | 一种可直接用于血清标志物检测的数字滚环扩增检测方法 |
| WO2023086880A1 (en) | 2021-11-10 | 2023-05-19 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of an analyte in a biological sample |
| EP4305195A2 (en) | 2021-12-01 | 2024-01-17 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
| WO2024102809A1 (en) | 2022-11-09 | 2024-05-16 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of multiple analytes in a biological sample |
| CN116625999B (zh) * | 2023-05-17 | 2023-11-28 | 中国科学院苏州生物医学工程技术研究所 | 一种评估零模波导孔有效载样的方法及其应用 |
| WO2025194315A1 (zh) * | 2024-03-18 | 2025-09-25 | 深圳华大智造科技股份有限公司 | 核酸检测方法及其应用 |
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| SE9400522D0 (sv) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| EP1985714B1 (en) | 1998-03-25 | 2012-02-29 | Olink AB | Method and kit for detecting a target molecule employing at least two affinity probes and rolling circle replication of padlock probes |
| WO2000004193A1 (en) * | 1998-07-20 | 2000-01-27 | Yale University | Method for detecting nucleic acids using target-mediated ligation of bipartite primers |
| AU2001267191A1 (en) | 2000-06-06 | 2001-12-17 | Tm Bioscience Corporation | Capture moieties for nucleic acids and uses thereof |
| DE60131903T2 (de) | 2000-10-24 | 2008-11-27 | The Board of Trustees of the Leland S. Stanford Junior University, Palo Alto | Direkte multiplex charakterisierung von genomischer dna |
| GB2378245A (en) | 2001-08-03 | 2003-02-05 | Mats Nilsson | Nucleic acid amplification method |
| AU2002366098A1 (en) | 2001-11-19 | 2003-06-10 | Parallele Bioscience Inc | Multiplex pcr |
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| US20070087355A1 (en) * | 2005-10-14 | 2007-04-19 | Barrett Michael T | Comparative genomic hybridization assays and compositions for practicing the same |
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| WO2008033442A2 (en) | 2006-09-12 | 2008-03-20 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for performing low background multiplex nucleic acid amplification reactions |
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| GB0921264D0 (en) | 2009-12-03 | 2010-01-20 | Olink Genomics Ab | Method for amplification of target nucleic acid |
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| JP2016513461A (ja) | 2013-03-12 | 2016-05-16 | カウンシル，インコーポレーテッド | 出生前遺伝子分析システム及び方法 |
| GB2520765A (en) | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Multiplex detection of nucleic acids |
| GB2520763A (en) | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Nucleic acid probe and method of detecting genomic fragments |
| US10174383B2 (en) * | 2014-08-13 | 2019-01-08 | Vanadis Diagnostics | Method of estimating the amount of a methylated locus in a sample |
-
2013
- 2013-12-02 GB GB1321196.6A patent/GB2520765A/en not_active Withdrawn
-
2014
- 2014-11-26 RU RU2016126375A patent/RU2733887C2/ru active
- 2014-11-26 BR BR112016012319-0A patent/BR112016012319B1/pt active IP Right Grant
- 2014-11-26 JP JP2016535001A patent/JP6749236B2/ja active Active
- 2014-11-26 WO PCT/IB2014/003062 patent/WO2015083002A2/en not_active Ceased
- 2014-11-26 ES ES20176773T patent/ES2987069T3/es active Active
- 2014-11-26 KR KR1020217030684A patent/KR102451174B1/ko active Active
- 2014-11-26 CN CN201480070068.5A patent/CN105934523B/zh active Active
- 2014-11-26 EP EP20176773.8A patent/EP3757228B1/en active Active
- 2014-11-26 ES ES14863081T patent/ES2807614T3/es active Active
- 2014-11-26 AU AU2014358862A patent/AU2014358862B2/en active Active
- 2014-11-26 CA CA2931015A patent/CA2931015C/en active Active
- 2014-11-26 EP EP14863081.7A patent/EP3077541B1/en active Active
- 2014-11-26 US US15/036,778 patent/US10526643B2/en active Active
- 2014-11-26 KR KR1020167017427A patent/KR102307230B1/ko active Active
-
2019
- 2019-11-14 US US16/683,763 patent/US20200140922A1/en active Pending
-
2020
- 2020-08-11 JP JP2020135592A patent/JP7091400B2/ja active Active
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