JP2020504709A5 - - Google Patents
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- Publication number
- JP2020504709A5 JP2020504709A5 JP2019525959A JP2019525959A JP2020504709A5 JP 2020504709 A5 JP2020504709 A5 JP 2020504709A5 JP 2019525959 A JP2019525959 A JP 2019525959A JP 2019525959 A JP2019525959 A JP 2019525959A JP 2020504709 A5 JP2020504709 A5 JP 2020504709A5
- Authority
- JP
- Japan
- Prior art keywords
- polynucleotide library
- polynucleotides
- percent
- genomic fragment
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091033319 polynucleotide Proteins 0.000 claims 74
- 102000040430 polynucleotide Human genes 0.000 claims 74
- 239000002157 polynucleotide Substances 0.000 claims 74
- 239000012634 fragment Substances 0.000 claims 20
- 238000000034 method Methods 0.000 claims 6
- 238000012163 sequencing technique Methods 0.000 claims 5
- 238000009396 hybridization Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 108700024394 Exon Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 230000003252 repetitive effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000002194 synthesizing effect Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022173718A JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2024192262A JP2025028854A (ja) | 2016-11-18 | 2024-10-31 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662424302P | 2016-11-18 | 2016-11-18 | |
| US62/424,302 | 2016-11-18 | ||
| US201762548307P | 2017-08-21 | 2017-08-21 | |
| US62/548,307 | 2017-08-21 | ||
| US201762558666P | 2017-09-14 | 2017-09-14 | |
| US62/558,666 | 2017-09-14 | ||
| PCT/US2017/062391 WO2018094263A1 (en) | 2016-11-18 | 2017-11-17 | Polynucleotide libraries having controlled stoichiometry and synthesis thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022173718A Division JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020504709A JP2020504709A (ja) | 2020-02-13 |
| JP2020504709A5 true JP2020504709A5 (https=) | 2020-12-24 |
Family
ID=62144787
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019525959A Pending JP2020504709A (ja) | 2016-11-18 | 2017-11-17 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2022173718A Pending JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2024192262A Pending JP2025028854A (ja) | 2016-11-18 | 2024-10-31 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022173718A Pending JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2024192262A Pending JP2025028854A (ja) | 2016-11-18 | 2024-10-31 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20180142289A1 (https=) |
| EP (1) | EP3541973B1 (https=) |
| JP (3) | JP2020504709A (https=) |
| KR (1) | KR102569164B1 (https=) |
| CN (1) | CN110382752A (https=) |
| AU (2) | AU2017363204B2 (https=) |
| CA (1) | CA3044057A1 (https=) |
| GB (1) | GB2572877A (https=) |
| IL (2) | IL266681B2 (https=) |
| WO (1) | WO2018094263A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI707038B (zh) | 2013-08-05 | 2020-10-11 | 美商扭轉生物科技有限公司 | 重新合成之基因庫 |
| WO2016126882A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| KR20180050411A (ko) | 2015-09-18 | 2018-05-14 | 트위스트 바이오사이언스 코포레이션 | 올리고핵산 변이체 라이브러리 및 그의 합성 |
| KR102794025B1 (ko) | 2015-09-22 | 2025-04-09 | 트위스트 바이오사이언스 코포레이션 | 핵산 합성을 위한 가요성 기판 |
| CN115920796A (zh) | 2015-12-01 | 2023-04-07 | 特韦斯特生物科学公司 | 功能化表面及其制备 |
| ES2956757T3 (es) | 2016-05-02 | 2023-12-27 | Becton Dickinson Co | Codificación con códigos de barras moleculares precisa |
| JP6854340B2 (ja) | 2016-08-22 | 2021-04-07 | ツイスト バイオサイエンス コーポレーション | デノボ合成された核酸ライブラリ |
| US10417457B2 (en) | 2016-09-21 | 2019-09-17 | Twist Bioscience Corporation | Nucleic acid based data storage |
| JP2020504709A (ja) * | 2016-11-18 | 2020-02-13 | ツイスト バイオサイエンス コーポレーション | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| KR102514213B1 (ko) | 2016-12-16 | 2023-03-27 | 트위스트 바이오사이언스 코포레이션 | 면역 시냅스의 변이체 라이브러리 및 그의 합성 |
| CN110892485B (zh) | 2017-02-22 | 2024-03-22 | 特韦斯特生物科学公司 | 基于核酸的数据存储 |
| WO2018170169A1 (en) | 2017-03-15 | 2018-09-20 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| US10696965B2 (en) | 2017-06-12 | 2020-06-30 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| CN111566125A (zh) | 2017-09-11 | 2020-08-21 | 特韦斯特生物科学公司 | Gpcr结合蛋白及其合成 |
| CN111565834B (zh) | 2017-10-20 | 2022-08-26 | 特韦斯特生物科学公司 | 用于多核苷酸合成的加热的纳米孔 |
| KR102804057B1 (ko) | 2018-01-04 | 2025-05-07 | 트위스트 바이오사이언스 코포레이션 | Dna 기반 디지털 정보 저장 |
| CA3100739A1 (en) | 2018-05-18 | 2019-11-21 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| US12357959B2 (en) | 2018-12-26 | 2025-07-15 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
| CA3131691A1 (en) | 2019-02-26 | 2020-09-03 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| CN113766930B (zh) | 2019-02-26 | 2025-07-22 | 特韦斯特生物科学公司 | Glp1受体的变异核酸文库 |
| AU2020298294A1 (en) | 2019-06-21 | 2022-02-17 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| WO2021061842A1 (en) | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for single domain antibodies |
| JP2022548309A (ja) | 2019-09-23 | 2022-11-17 | ツイスト バイオサイエンス コーポレーション | Ｃｒｔｈ２のバリアント核酸ライブラリー |
| US11708605B2 (en) | 2019-11-06 | 2023-07-25 | Adaptive Biotechnologies Corporation | Synthetic strands for nucleic acid sequencing and related methods and systems |
| CN110853708B (zh) * | 2019-11-13 | 2022-03-08 | 上海仁东医学检验所有限公司 | 用于hla分型的核酸捕获探针的设计方法 |
| IL293670A (en) | 2019-12-09 | 2022-08-01 | Twist Bioscience Corp | Variable nucleic acid libraries for adenosine receptors |
| MX2022013499A (es) | 2020-04-27 | 2023-01-16 | Twist Bioscience Corp | Bibliotecas de ácidos nucleicos variantes para coronavirus. |
| US11655503B2 (en) | 2020-05-11 | 2023-05-23 | Personal Genome Diagnostics Inc. | Selective capture of target DNA sequences |
| KR20230034941A (ko) * | 2020-05-28 | 2023-03-10 | 일루미나, 인코포레이티드 | 상이한 특징을 갖는 폴리뉴클레오티드 사본 비교 |
| US12391762B2 (en) | 2020-08-26 | 2025-08-19 | Twist Bioscience Corporation | Methods and compositions relating to GLP1R variants |
| CA3190917A1 (en) | 2020-08-28 | 2022-03-03 | Andres Fernandez | Devices and methods for synthesis |
| WO2022086866A1 (en) | 2020-10-19 | 2022-04-28 | Twist Bioscience Corporation | Methods of synthesizing oligonucleotides using tethered nucleotides |
| WO2022159620A1 (en) | 2021-01-21 | 2022-07-28 | Twist Bioscience Corporation | Methods and compositions relating to adenosine receptors |
| BE1029144B1 (fr) * | 2021-02-25 | 2022-09-20 | Oncodna | Méthode de caracterisation d'une tumeur à l'aide d'un séquençage ciblé |
| EP4314075A4 (en) | 2021-03-24 | 2025-04-09 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CD3 |
| WO2022235584A1 (en) | 2021-05-03 | 2022-11-10 | Twist Bioscience Corporation | Variant nucleic acid libraries for glycans |
| WO2022271884A2 (en) | 2021-06-22 | 2022-12-29 | Twist Bioscience Corporation | Methods and compositions relating to covid antibody epitopes |
| EP4388118A4 (en) | 2021-08-19 | 2025-05-21 | Twist Bioscience Corporation | METHODS AND COMPOSITIONS IN COMPOSITION WITH COVALENTLY CLOSED NUCLEIC ACIDS |
| IL312714A (en) | 2021-11-18 | 2024-07-01 | Twist Bioscience Corp | DICKKOPF-1 variant antibodies and methods of use |
| US12325739B2 (en) | 2022-01-03 | 2025-06-10 | Twist Bioscience Corporation | Bispecific SARS-CoV-2 antibodies and methods of use |
| CN116417071B (zh) * | 2023-04-07 | 2026-04-03 | 祥符实验室 | 一种dna数据存储的选择性访问方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5474796A (en) | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| JP2005535283A (ja) * | 2001-11-13 | 2005-11-24 | ルビコン ゲノミクス インコーポレイテッド | ランダムフラグメント化により生成されたｄｎａ分子を用いたｄｎａ増幅および配列決定 |
| US9598737B2 (en) * | 2012-05-09 | 2017-03-21 | Longhorn Vaccines And Diagnostics, Llc | Next generation genomic sequencing methods |
| EP2334802A4 (en) * | 2008-09-09 | 2012-01-25 | Life Technologies Corp | METHODS OF GENERATING SPECIFIC LIBRARIES OF GENES |
| US8828688B2 (en) * | 2010-05-27 | 2014-09-09 | Affymetrix, Inc. | Multiplex amplification methods |
| US10457936B2 (en) * | 2011-02-02 | 2019-10-29 | University Of Washington Through Its Center For Commercialization | Massively parallel contiguity mapping |
| CN111876409A (zh) * | 2012-04-24 | 2020-11-03 | Gen9股份有限公司 | 在体外克隆中分选核酸和多重制备物的方法 |
| US20150197787A1 (en) * | 2012-08-02 | 2015-07-16 | Qiagen Gmbh | Recombinase mediated targeted dna enrichment for next generation sequencing |
| CN113337604A (zh) * | 2013-03-15 | 2021-09-03 | 莱兰斯坦福初级大学评议会 | 循环核酸肿瘤标志物的鉴别和用途 |
| TWI707038B (zh) * | 2013-08-05 | 2020-10-11 | 美商扭轉生物科技有限公司 | 重新合成之基因庫 |
| WO2015031689A1 (en) * | 2013-08-30 | 2015-03-05 | Personalis, Inc. | Methods and systems for genomic analysis |
| CN106170560A (zh) * | 2013-10-29 | 2016-11-30 | 长角牛疫苗和诊断有限责任公司 | 下一代基因组测序方法 |
| JP2020504709A (ja) * | 2016-11-18 | 2020-02-13 | ツイスト バイオサイエンス コーポレーション | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
-
2017
- 2017-11-17 JP JP2019525959A patent/JP2020504709A/ja active Pending
- 2017-11-17 GB GB1908719.6A patent/GB2572877A/en not_active Withdrawn
- 2017-11-17 WO PCT/US2017/062391 patent/WO2018094263A1/en not_active Ceased
- 2017-11-17 CA CA3044057A patent/CA3044057A1/en active Pending
- 2017-11-17 KR KR1020197017281A patent/KR102569164B1/ko active Active
- 2017-11-17 CN CN201780084031.1A patent/CN110382752A/zh active Pending
- 2017-11-17 IL IL266681A patent/IL266681B2/en unknown
- 2017-11-17 AU AU2017363204A patent/AU2017363204B2/en not_active Ceased
- 2017-11-17 IL IL314890A patent/IL314890A/en unknown
- 2017-11-17 EP EP17872347.4A patent/EP3541973B1/en active Active
- 2017-11-17 US US15/816,995 patent/US20180142289A1/en not_active Abandoned
-
2021
- 2021-06-17 US US17/350,750 patent/US20210348220A1/en not_active Abandoned
-
2022
- 2022-10-28 JP JP2022173718A patent/JP2023017863A/ja active Pending
-
2023
- 2023-02-15 AU AU2023200850A patent/AU2023200850A1/en not_active Abandoned
-
2024
- 2024-10-31 JP JP2024192262A patent/JP2025028854A/ja active Pending
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