JP2020504709A5 - - Google Patents
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- Publication number
- JP2020504709A5 JP2020504709A5 JP2019525959A JP2019525959A JP2020504709A5 JP 2020504709 A5 JP2020504709 A5 JP 2020504709A5 JP 2019525959 A JP2019525959 A JP 2019525959A JP 2019525959 A JP2019525959 A JP 2019525959A JP 2020504709 A5 JP2020504709 A5 JP 2020504709A5
- Authority
- JP
- Japan
- Prior art keywords
- polynucleotide library
- polynucleotides
- percent
- genomic fragment
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091033319 polynucleotide Proteins 0.000 claims 74
- 102000040430 polynucleotide Human genes 0.000 claims 74
- 239000002157 polynucleotide Substances 0.000 claims 74
- 239000012634 fragment Substances 0.000 claims 20
- 238000000034 method Methods 0.000 claims 6
- 238000012163 sequencing technique Methods 0.000 claims 5
- 238000009396 hybridization Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 108700024394 Exon Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 230000003252 repetitive effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000002194 synthesizing effect Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022173718A JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2024192262A JP2025028854A (ja) | 2016-11-18 | 2024-10-31 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662424302P | 2016-11-18 | 2016-11-18 | |
| US62/424,302 | 2016-11-18 | ||
| US201762548307P | 2017-08-21 | 2017-08-21 | |
| US62/548,307 | 2017-08-21 | ||
| US201762558666P | 2017-09-14 | 2017-09-14 | |
| US62/558,666 | 2017-09-14 | ||
| PCT/US2017/062391 WO2018094263A1 (en) | 2016-11-18 | 2017-11-17 | Polynucleotide libraries having controlled stoichiometry and synthesis thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022173718A Division JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020504709A JP2020504709A (ja) | 2020-02-13 |
| JP2020504709A5 true JP2020504709A5 (https=) | 2020-12-24 |
Family
ID=62144787
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019525959A Pending JP2020504709A (ja) | 2016-11-18 | 2017-11-17 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2022173718A Pending JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2024192262A Pending JP2025028854A (ja) | 2016-11-18 | 2024-10-31 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022173718A Pending JP2023017863A (ja) | 2016-11-18 | 2022-10-28 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
| JP2024192262A Pending JP2025028854A (ja) | 2016-11-18 | 2024-10-31 | 制御された化学量論を有するポリヌクレオチドライブラリおよびその合成 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20180142289A1 (https=) |
| EP (1) | EP3541973B1 (https=) |
| JP (3) | JP2020504709A (https=) |
| KR (1) | KR102569164B1 (https=) |
| CN (1) | CN110382752A (https=) |
| AU (2) | AU2017363204B2 (https=) |
| CA (1) | CA3044057A1 (https=) |
| GB (1) | GB2572877A (https=) |
| IL (2) | IL266681B2 (https=) |
| WO (1) | WO2018094263A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201600853UA (en) | 2013-08-05 | 2016-03-30 | Twist Bioscience Corp | De novo synthesized gene libraries |
| US10669304B2 (en) | 2015-02-04 | 2020-06-02 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| EP3350314A4 (en) | 2015-09-18 | 2019-02-06 | Twist Bioscience Corporation | OLIGONUCLEIC ACID VARIANT LIBRARIES VARIANT AND SYNTHESIS THEREOF |
| KR102794025B1 (ko) | 2015-09-22 | 2025-04-09 | 트위스트 바이오사이언스 코포레이션 | 핵산 합성을 위한 가요성 기판 |
| CN115920796A (zh) | 2015-12-01 | 2023-04-07 | 特韦斯特生物科学公司 | 功能化表面及其制备 |
| JP7129343B2 (ja) * | 2016-05-02 | 2022-09-01 | ベクトン・ディキンソン・アンド・カンパニー | 正確な分子バーコーディング |
| EP3500672A4 (en) | 2016-08-22 | 2020-05-20 | Twist Bioscience Corporation | DE NOVO SYNTHETIZED NUCLEIC ACID LIBRARIES |
| US10417457B2 (en) | 2016-09-21 | 2019-09-17 | Twist Bioscience Corporation | Nucleic acid based data storage |
| IL266681B2 (en) * | 2016-11-18 | 2025-01-01 | Twist Bioscience Corp | Polynucleotide libraries with controlled stoichiometry and their synthesis |
| GB2573069A (en) | 2016-12-16 | 2019-10-23 | Twist Bioscience Corp | Variant libraries of the immunological synapse and synthesis thereof |
| EP4556433A3 (en) | 2017-02-22 | 2025-08-06 | Twist Bioscience Corporation | Nucleic acid based data storage |
| WO2018170169A1 (en) | 2017-03-15 | 2018-09-20 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2018231872A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
| CN111565834B (zh) | 2017-10-20 | 2022-08-26 | 特韦斯特生物科学公司 | 用于多核苷酸合成的加热的纳米孔 |
| KR102804057B1 (ko) | 2018-01-04 | 2025-05-07 | 트위스트 바이오사이언스 코포레이션 | Dna 기반 디지털 정보 저장 |
| CA3100739A1 (en) | 2018-05-18 | 2019-11-21 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| WO2020139871A1 (en) | 2018-12-26 | 2020-07-02 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
| CN113766930B (zh) | 2019-02-26 | 2025-07-22 | 特韦斯特生物科学公司 | Glp1受体的变异核酸文库 |
| JP2022522668A (ja) | 2019-02-26 | 2022-04-20 | ツイスト バイオサイエンス コーポレーション | 抗体を最適化するための変異体核酸ライブラリ |
| US11332738B2 (en) | 2019-06-21 | 2022-05-17 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| EP4034566A4 (en) | 2019-09-23 | 2024-01-24 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CRTH2 |
| JP2022548783A (ja) | 2019-09-23 | 2022-11-21 | ツイスト バイオサイエンス コーポレーション | 単一ドメイン抗体のバリアント核酸ライブラリー |
| EP4055159A4 (en) | 2019-11-06 | 2024-04-17 | Adaptive Biotechnologies Corporation | SYNTHETIC STRANDS FOR NUCLEIC ACID SEQUENCING AND RELATED METHODS AND SYSTEMS |
| CN110853708B (zh) * | 2019-11-13 | 2022-03-08 | 上海仁东医学检验所有限公司 | 用于hla分型的核酸捕获探针的设计方法 |
| BR112022011235A2 (pt) | 2019-12-09 | 2022-12-13 | Twist Bioscience Corp | Bibliotecas de variantes de ácido nucleico para receptores de adenosina |
| MX2022013499A (es) | 2020-04-27 | 2023-01-16 | Twist Bioscience Corp | Bibliotecas de ácidos nucleicos variantes para coronavirus. |
| KR20230034950A (ko) * | 2020-05-11 | 2023-03-10 | 퍼스널 게놈 다이아그노스틱스 인코포레이티드 | 표적 dna 서열의 선택적 포획 |
| US20210371908A1 (en) * | 2020-05-28 | 2021-12-02 | Illumina, Inc. | Comparing copies of polynucleotides with different features |
| EP4204460A4 (en) | 2020-08-26 | 2024-09-25 | Twist Bioscience Corporation | METHODS AND COMPOSITIONS RELATING TO GLP1R VARIANTS |
| CN117043171A (zh) | 2020-08-28 | 2023-11-10 | 特韦斯特生物科学公司 | 用于合成的装置和方法 |
| EP4229210A4 (en) | 2020-10-19 | 2025-01-08 | Twist Bioscience Corporation | METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDES USING BOUND NUCLEOTIDES |
| KR20230147617A (ko) | 2021-01-21 | 2023-10-23 | 트위스트 바이오사이언스 코포레이션 | 아데노신 수용체에 관한 방법 및 조성물 |
| BE1029144B1 (fr) * | 2021-02-25 | 2022-09-20 | Oncodna | Méthode de caracterisation d'une tumeur à l'aide d'un séquençage ciblé |
| EP4314075A4 (en) | 2021-03-24 | 2025-04-09 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CD3 |
| WO2022235584A1 (en) | 2021-05-03 | 2022-11-10 | Twist Bioscience Corporation | Variant nucleic acid libraries for glycans |
| US12201857B2 (en) | 2021-06-22 | 2025-01-21 | Twist Bioscience Corporation | Methods and compositions relating to covid antibody epitopes |
| WO2023023285A2 (en) | 2021-08-19 | 2023-02-23 | Twist Bioscience Corporation | Methods and compositions relating to covalently closed nucleic acids |
| US12134656B2 (en) | 2021-11-18 | 2024-11-05 | Twist Bioscience Corporation | Dickkopf-1 variant antibodies and methods of use |
| EP4460516A2 (en) | 2022-01-03 | 2024-11-13 | Twist Bioscience Corporation | Bispecific sars-cov-2 antibodies and methods of use |
| CN116417071B (zh) * | 2023-04-07 | 2026-04-03 | 祥符实验室 | 一种dna数据存储的选择性访问方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5474796A (en) | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| JP2005535283A (ja) * | 2001-11-13 | 2005-11-24 | ルビコン ゲノミクス インコーポレイテッド | ランダムフラグメント化により生成されたｄｎａ分子を用いたｄｎａ増幅および配列決定 |
| US9598737B2 (en) * | 2012-05-09 | 2017-03-21 | Longhorn Vaccines And Diagnostics, Llc | Next generation genomic sequencing methods |
| EP2334802A4 (en) * | 2008-09-09 | 2012-01-25 | Life Technologies Corp | METHODS OF GENERATING SPECIFIC LIBRARIES OF GENES |
| US8828688B2 (en) * | 2010-05-27 | 2014-09-09 | Affymetrix, Inc. | Multiplex amplification methods |
| CN103443338B (zh) * | 2011-02-02 | 2017-09-22 | 华盛顿大学商业化中心 | 大规模平行邻接作图 |
| CA2871505C (en) * | 2012-04-24 | 2021-10-12 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
| WO2014020137A1 (en) * | 2012-08-02 | 2014-02-06 | Qiagen Gmbh | Recombinase mediated targeted dna enrichment for next generation sequencing |
| WO2014151117A1 (en) * | 2013-03-15 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Identification and use of circulating nucleic acid tumor markers |
| SG11201600853UA (en) * | 2013-08-05 | 2016-03-30 | Twist Bioscience Corp | De novo synthesized gene libraries |
| WO2015031689A1 (en) * | 2013-08-30 | 2015-03-05 | Personalis, Inc. | Methods and systems for genomic analysis |
| CN106170560A (zh) * | 2013-10-29 | 2016-11-30 | 长角牛疫苗和诊断有限责任公司 | 下一代基因组测序方法 |
| IL266681B2 (en) * | 2016-11-18 | 2025-01-01 | Twist Bioscience Corp | Polynucleotide libraries with controlled stoichiometry and their synthesis |
-
2017
- 2017-11-17 IL IL266681A patent/IL266681B2/en unknown
- 2017-11-17 WO PCT/US2017/062391 patent/WO2018094263A1/en not_active Ceased
- 2017-11-17 IL IL314890A patent/IL314890A/en unknown
- 2017-11-17 US US15/816,995 patent/US20180142289A1/en not_active Abandoned
- 2017-11-17 CA CA3044057A patent/CA3044057A1/en active Pending
- 2017-11-17 KR KR1020197017281A patent/KR102569164B1/ko active Active
- 2017-11-17 AU AU2017363204A patent/AU2017363204B2/en not_active Ceased
- 2017-11-17 GB GB1908719.6A patent/GB2572877A/en not_active Withdrawn
- 2017-11-17 EP EP17872347.4A patent/EP3541973B1/en active Active
- 2017-11-17 CN CN201780084031.1A patent/CN110382752A/zh active Pending
- 2017-11-17 JP JP2019525959A patent/JP2020504709A/ja active Pending
-
2021
- 2021-06-17 US US17/350,750 patent/US20210348220A1/en not_active Abandoned
-
2022
- 2022-10-28 JP JP2022173718A patent/JP2023017863A/ja active Pending
-
2023
- 2023-02-15 AU AU2023200850A patent/AU2023200850A1/en not_active Abandoned
-
2024
- 2024-10-31 JP JP2024192262A patent/JP2025028854A/ja active Pending
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