JP2020536953A - デキストロメトルファン経皮送達デバイス - Google Patents

デキストロメトルファン経皮送達デバイス Download PDF

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Publication number
JP2020536953A
JP2020536953A JP2020540680A JP2020540680A JP2020536953A JP 2020536953 A JP2020536953 A JP 2020536953A JP 2020540680 A JP2020540680 A JP 2020540680A JP 2020540680 A JP2020540680 A JP 2020540680A JP 2020536953 A JP2020536953 A JP 2020536953A
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Prior art keywords
dextromethorphan
application
day
average
transdermal delivery
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JP2020540680A
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Japanese (ja)
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JP2020536953A5 (https=
Inventor
スレシュ ボルサディア
スレシュ ボルサディア
Original Assignee
シンケイ セラピューティクス リミテッド ライアビリティ カンパニー
シンケイ セラピューティクス リミテッド ライアビリティ カンパニー
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Application filed by シンケイ セラピューティクス リミテッド ライアビリティ カンパニー, シンケイ セラピューティクス リミテッド ライアビリティ カンパニー filed Critical シンケイ セラピューティクス リミテッド ライアビリティ カンパニー
Publication of JP2020536953A publication Critical patent/JP2020536953A/ja
Publication of JP2020536953A5 publication Critical patent/JP2020536953A5/ja
Priority to JP2023136898A priority Critical patent/JP7609943B2/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020540680A 2017-10-04 2018-10-03 デキストロメトルファン経皮送達デバイス Pending JP2020536953A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023136898A JP7609943B2 (ja) 2017-10-04 2023-08-25 デキストロメトルファン経皮送達デバイス

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762568028P 2017-10-04 2017-10-04
US62/568,028 2017-10-04
US201862680182P 2018-06-04 2018-06-04
US62/680,182 2018-06-04
PCT/US2018/054178 WO2019070864A1 (en) 2017-10-04 2018-10-03 DEVICE FOR TRANSDERMAL DEXTROMETHORPHAN DELIVERY

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023136898A Division JP7609943B2 (ja) 2017-10-04 2023-08-25 デキストロメトルファン経皮送達デバイス

Publications (2)

Publication Number Publication Date
JP2020536953A true JP2020536953A (ja) 2020-12-17
JP2020536953A5 JP2020536953A5 (https=) 2021-11-04

Family

ID=65994772

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020540680A Pending JP2020536953A (ja) 2017-10-04 2018-10-03 デキストロメトルファン経皮送達デバイス
JP2023136898A Active JP7609943B2 (ja) 2017-10-04 2023-08-25 デキストロメトルファン経皮送達デバイス

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023136898A Active JP7609943B2 (ja) 2017-10-04 2023-08-25 デキストロメトルファン経皮送達デバイス

Country Status (13)

Country Link
US (3) US11382869B2 (https=)
EP (1) EP3691641A4 (https=)
JP (2) JP2020536953A (https=)
KR (1) KR20200062254A (https=)
CN (1) CN111343980B (https=)
AU (1) AU2018345723B2 (https=)
BR (1) BR112020006723A2 (https=)
CA (1) CA3078369A1 (https=)
IL (1) IL273735B2 (https=)
MX (1) MX2020003044A (https=)
TW (1) TWI795446B (https=)
WO (1) WO2019070864A1 (https=)
ZA (1) ZA202001834B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024503114A (ja) * 2021-01-18 2024-01-24 アンテシップ バイオベンチャーズ トゥー エルエルシー 神経精神疾患に対する抗うつ剤とデキストロメトルファンとの組み合わせ

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI795446B (zh) * 2017-10-04 2023-03-11 美商神經治療股份有限公司 右旋美索芬(dextromethorphan)經皮輸送裝置
EP4125902A4 (en) * 2020-03-30 2024-05-22 Shinkei Therapeutics, Inc. TRANSDERMAL ADMINISTRATION OF DEXTROMETHORPHAN
EP4183391A4 (en) * 2020-07-20 2024-04-17 Shenzhen Salubris Pharmaceuticals Co., Ltd. PHARMACEUTICAL COMPOSITION AND ITS USE
CN113720944B (zh) * 2021-09-30 2023-04-28 珠海润都制药股份有限公司 一种氢溴酸右美沙芬硫酸奎尼丁胶囊含量的检测方法
TW202430177A (zh) * 2022-10-06 2024-08-01 美商神經治療股份有限公司 右旋美索芬之經皮輸送

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04297415A (ja) * 1991-03-27 1992-10-21 Mitsui Petrochem Ind Ltd 薬物投与用粘着剤
JP2000509037A (ja) * 1996-04-23 2000-07-18 フアーマシア・アンド・アツプジヨン・アー・ベー 鎮咳剤として経皮投与されるデキストロメトルファン
JP2009525343A (ja) * 2006-02-03 2009-07-09 アバニール・ファーマシューティカルズ 鬱病、不安および神経変性疾患を治療するためのデキストロメトルファンおよびキニジンを含む薬剤組成物
US20160038464A1 (en) * 2012-04-16 2016-02-11 Antecip Bioventures Ii Llc Compositions and Methods Comprising Celecoxib or Related Compounds and Dextromethorphan
JP2016535786A (ja) * 2013-11-05 2016-11-17 アンテシップ バイオベンチャーズ トゥー エルエルシー ブプロピオンまたは関連組成物およびデキストロメトルファンを含む組成物および方法

Family Cites Families (13)

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US5206248A (en) 1992-03-27 1993-04-27 Smith Richard A Method for reducing emotional lability
JP3021661B2 (ja) * 1994-03-07 2000-03-15 セラテック・インコーポレーテッド 薬剤含有接着複合体の経皮放出デバイス
TWI326214B (en) 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
SI1530469T1 (sl) * 2002-08-20 2009-06-30 Euro Celtique Sa Transdermalna odmerna oblika, ki obsega aktivno sredstvo in antagonist v obliki soli in v obliki proste baze
KR20060126701A (ko) * 2003-12-10 2006-12-08 애크럭스 디디에스 피티와이 리미티드 경피 또는 국소 약물 전달에 따른 원치않는 효과의치료방법
US20060223786A1 (en) 2005-04-01 2006-10-05 Smith David J Transdermal pain control method and device
ATE481096T1 (de) * 2005-04-06 2010-10-15 Adamas Pharmaceuticals Inc Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen
US20070248657A1 (en) * 2006-04-25 2007-10-25 Smith David J Multi-compartment transdermal pain control device
CA2676133A1 (en) * 2006-10-09 2008-04-17 Smithkline Beecham Corporation Compositions for reducing nicotine withdrawal symptoms and/or tobacco usage
WO2009021058A2 (en) 2007-08-06 2009-02-12 Trinity Labortories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
WO2010062690A1 (en) 2008-10-30 2010-06-03 Concert Pharmaceuticals Inc. Combination of morphinan compounds and antidepressant for the treatment of pseudobulbar affect, neurological diseases, intractable and chronic pain and brain injury
RU2544702C2 (ru) * 2009-04-24 2015-03-20 Хенкель Корпорейшн Клеи на основе силикон-акрилового гибридного полимера
TWI795446B (zh) * 2017-10-04 2023-03-11 美商神經治療股份有限公司 右旋美索芬(dextromethorphan)經皮輸送裝置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04297415A (ja) * 1991-03-27 1992-10-21 Mitsui Petrochem Ind Ltd 薬物投与用粘着剤
JP2000509037A (ja) * 1996-04-23 2000-07-18 フアーマシア・アンド・アツプジヨン・アー・ベー 鎮咳剤として経皮投与されるデキストロメトルファン
JP2009525343A (ja) * 2006-02-03 2009-07-09 アバニール・ファーマシューティカルズ 鬱病、不安および神経変性疾患を治療するためのデキストロメトルファンおよびキニジンを含む薬剤組成物
US20160038464A1 (en) * 2012-04-16 2016-02-11 Antecip Bioventures Ii Llc Compositions and Methods Comprising Celecoxib or Related Compounds and Dextromethorphan
JP2016535786A (ja) * 2013-11-05 2016-11-17 アンテシップ バイオベンチャーズ トゥー エルエルシー ブプロピオンまたは関連組成物およびデキストロメトルファンを含む組成物および方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024503114A (ja) * 2021-01-18 2024-01-24 アンテシップ バイオベンチャーズ トゥー エルエルシー 神経精神疾患に対する抗うつ剤とデキストロメトルファンとの組み合わせ

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Publication number Publication date
CA3078369A1 (en) 2019-04-11
US20240189252A1 (en) 2024-06-13
EP3691641A4 (en) 2021-04-07
MX2020003044A (es) 2020-08-13
ZA202001834B (en) 2024-10-30
IL273735B1 (en) 2024-04-01
IL273735B2 (en) 2024-08-01
CN111343980A (zh) 2020-06-26
AU2018345723A8 (en) 2020-04-23
JP7609943B2 (ja) 2025-01-07
BR112020006723A2 (pt) 2020-10-06
WO2019070864A1 (en) 2019-04-11
EP3691641A1 (en) 2020-08-12
US20220331264A1 (en) 2022-10-20
AU2018345723A1 (en) 2020-04-16
RU2020115169A3 (https=) 2022-02-16
US11382869B2 (en) 2022-07-12
US20200323788A1 (en) 2020-10-15
IL273735A (en) 2020-05-31
TW201922232A (zh) 2019-06-16
RU2020115169A (ru) 2021-11-08
CN111343980B (zh) 2024-02-27
AU2018345723B2 (en) 2024-09-19
JP2023159366A (ja) 2023-10-31
KR20200062254A (ko) 2020-06-03
TWI795446B (zh) 2023-03-11

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