JP2020536098A - グリシン脳症を治療するためのベンゾエート含有組成物の使用 - Google Patents

グリシン脳症を治療するためのベンゾエート含有組成物の使用 Download PDF

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Publication number
JP2020536098A
JP2020536098A JP2020519254A JP2020519254A JP2020536098A JP 2020536098 A JP2020536098 A JP 2020536098A JP 2020519254 A JP2020519254 A JP 2020519254A JP 2020519254 A JP2020519254 A JP 2020519254A JP 2020536098 A JP2020536098 A JP 2020536098A
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patient
glyceryl
pharmaceutical composition
formulation
effective amount
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JP2020519254A
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Japanese (ja)
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JP2020536098A5 (enExample
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パハン，カリパダ
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ラッシュ・ユニバーシティ・メディカル・センター
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Publication of JP2020536098A publication Critical patent/JP2020536098A/ja
Publication of JP2020536098A5 publication Critical patent/JP2020536098A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020519254A 2017-10-06 2018-09-26 グリシン脳症を治療するためのベンゾエート含有組成物の使用 Pending JP2020536098A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762569251P 2017-10-06 2017-10-06
US62/569,251 2017-10-06
PCT/US2018/052879 WO2019070478A1 (en) 2017-10-06 2018-09-26 USE OF A BENZOATE-CONTAINING COMPOSITION FOR TREATING GLYCINIC ENCEPHALOPATHY

Publications (2)

Publication Number Publication Date
JP2020536098A true JP2020536098A (ja) 2020-12-10
JP2020536098A5 JP2020536098A5 (enExample) 2021-08-12

Family

ID=65994915

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020519254A Pending JP2020536098A (ja) 2017-10-06 2018-09-26 グリシン脳症を治療するためのベンゾエート含有組成物の使用

Country Status (10)

Country Link
US (1) US11304923B2 (enExample)
EP (1) EP3691630A4 (enExample)
JP (1) JP2020536098A (enExample)
KR (1) KR20200065012A (enExample)
CN (1) CN111212637A (enExample)
AU (2) AU2018345244A1 (enExample)
BR (1) BR112020005856A2 (enExample)
CA (1) CA3078609A1 (enExample)
EA (1) EA202090666A1 (enExample)
WO (1) WO2019070478A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020229316A1 (en) * 2019-02-25 2021-09-16 Rush University Medical Center Compositions including cinnamic acid and methods of use thereof
JP2022541021A (ja) * 2019-07-16 2022-09-21 ラッシュ・ユニバーシティ・メディカル・センター 神経変性障害を治療するためのベンゾエート含有組成物の使用
EP4262781A4 (en) * 2020-12-16 2025-02-12 Rush University Medical Center Administration of glycerol tribenzoate and glycerol phenylbutyrate for treatment of neurodegenerative and urea cycle disorders

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015509489A (ja) * 2012-02-10 2015-03-30 ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ がんの処置のためのグリシン開裂系の阻害
JP2017505811A (ja) * 2014-01-17 2017-02-23 ラッシュ・ユニバーシティ・メディカル・センター 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015509489A (ja) * 2012-02-10 2015-03-30 ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ がんの処置のためのグリシン開裂系の阻害
JP2017505811A (ja) * 2014-01-17 2017-02-23 ラッシュ・ユニバーシティ・メディカル・センター 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, vol. 16, JPN6022029402, 2017, pages 868 - 880, ISSN: 0004995495 *
J. INHERIT. METAB. DIS., vol. 28, JPN6022029400, 2005, pages 651 - 663, ISSN: 0004995496 *

Also Published As

Publication number Publication date
KR20200065012A (ko) 2020-06-08
CA3078609A1 (en) 2019-04-11
EP3691630A1 (en) 2020-08-12
EA202090666A1 (ru) 2020-08-05
US20200281884A1 (en) 2020-09-10
BR112020005856A2 (pt) 2020-09-29
AU2022200277A1 (en) 2022-02-03
WO2019070478A1 (en) 2019-04-11
EP3691630A4 (en) 2021-10-27
US11304923B2 (en) 2022-04-19
CN111212637A (zh) 2020-05-29
AU2018345244A1 (en) 2020-04-02

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